• Furthermore, dual in situ hybridization detected positive signals for itr1 and cox2 at the same site, implying that ITR1 may regulate cox2 gene expression. (frontiersin.org)
  • To understand the molecular-genetic basis of functional specialization and identify potential drug targets specific to each neuron subtype, we performed a genome wide assessment of both gene expression and splicing across EXC, PV, SST and VIP neurons from male and female mouse brains. (jneurosci.org)
  • These results reveal numerous examples where neuron subtype-specific gene expression, as well as splice-isoform usage, can explain functional differences between neuron subtypes, including in presynaptic plasticity, postsynaptic receptor function, and synaptic connectivity specification. (jneurosci.org)
  • This resource, combining a unique new dataset and novel application of analysis methods to multiple relevant datasets, identifies numerous potential drug targets for manipulating circuit function, reveals neuron subtype-specific roles for disease-linked genes, and is useful for understanding gene expression changes observed in human patient brains. (jneurosci.org)
  • We used a genome-wide analysis which not only examined differential gene expression levels but could also detect differences in splice isoform usage. (jneurosci.org)
  • Our data have provided evidence for a comparable prediction of clinical outcome in CMF-treated breast cancer patients using conventional clinical variables and gene expression based markers. (lu.se)
  • The intensive exposure of the liver cells to any type of noxae, such as viruses , drugs , alcohols , and xenobiotics could induce hepatic inflammation through the upregulation of gene expression of several fibrotic and inflammatory mediators. (bvsalud.org)
  • The presence of BDNF and GDNF mRNA was determined by RT-PCR and protein expression was evaluated by Western Blot. (sld.cu)
  • Results Strong hypoxia-inducible factor-2 protein expression was detected in CD138 + multiple myeloma plasma cells in patients' biopsy specimens. (haematologica.org)
  • We provide a searchable web resource for exploring differential mRNA expression and splice form usage between excitatory, PV, SST, and VIP neurons ( http://research-pub.gene.com/NeuronSubtypeTranscriptomes ). (jneurosci.org)
  • We sorted excitatory neurons and key inhibitory neuron subtypes from mouse brains and assessed differential mRNA expression. (jneurosci.org)
  • Differential expression of zinc-dependent matrix metalloproteinases (MMPs) is largely responsible for collagen remodeling. (sages.org)
  • Ge S.X., Son EW, Yao RN, iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data, BMC Bioinformatics 19:124, 2018. (sdstate.edu)
  • Although data from multiple studies suggest that HFE genetic mutations are common, the frequency of phenotypic expression and therefore the clinical consequences of the mutation remain unclear. (medscape.com)
  • qPCR-based methods for expression analysis of miRNAs. (nih.gov)
  • In most cases, expressions are used to express boolean values. (apache.org)
  • Proof obligations are Syntheto boolean expressions universally quantified over its explicitly typed free variables. (utexas.edu)
  • In addition to the entities mentioned above, since we need to generate proof obligations, the context also includes conditions (boolean expressions) collected as expressions are traversed. (utexas.edu)
  • Kv2.1 expression is consistently high throughout all cortical layers, especially in layer (L) 5b pyramidal neurons, whereas Kv2.2 expression is primarily limited to neurons in L2 and L5a. (jneurosci.org)
  • Immunocytochemistry and voltage-clamp recordings from outside-out macropatches reveal distinct cellular expression patterns for Kv2.1 and Kv2.2 in intratelencephalic and pyramidal tract neurons of L5, indicating circuit-specific requirements for these Kv2 paralogs. (jneurosci.org)
  • The role of hypoxia-inducible factors-1 and -2 in the regulation of CXCL12 expression was examined using over-expression and short hairpin RNA knockdown constructs, electrophoretic mobility shift assays and chromatin immunoprecipitation. (haematologica.org)
  • Kv2.1 exhibits robust expression across many neuron types and is unique in its conditional role in modulating intrinsic excitability through changes in its phosphorylation state, which affect Kv2.1 expression, localization, and function. (jneurosci.org)
  • This freedom includes the right to express points of view on the widest range of public and private concerns and to engage in the robust expression of ideas. (thefire.org)
  • FCM analysis found that human NP cells with increased FasL expression resulted in significantly increased apoptosis ratio of macrophages and CD8 + T cells. (medsci.org)
  • Nuclear factor erythroid 2-related factor 2 (Nrf2) and HO-1 expression significantly increased in IMI rats and IMI rats that received PN. (hindawi.com)
  • and rapidly determine all the DNA sequences in the genome that regulate the expression of a specific gene. (finchannel.com)
  • Multi-walled carbon nanotube s induce proinflammatory cytokine expression by activating NF-kB signaling in mouse lungs. (cdc.gov)
  • Since 'X comprehensions' are advertised as and intended to be functionally equivalent to `X(generator expression)', I use just 'generator expressions' to refer to all. (python.org)
  • These studies have confirmed that facial and body expressions increase perceived safety during human-robot interaction. (springer.com)
  • Social awareness refers to how people behave, their facial expressions, where they're looking, their articulated pose and how they interact with each other. (ge.com)
  • Learning person-specific models for facial expression and action unit recognition. (ge.com)
  • The expression pattern of these proteins in BMSC has not been well characterized. (sld.cu)
  • At each maturation stage, expression of proteins affects the commitment to move to the next stage. (lu.se)
  • Presented by FIRE and College Pulse, the 2024 College Free Speech Rankings is the largest survey of campus free expression ever performed. (thefire.org)
  • Be sure to sign up for a free Gaia Goddess Membership! (gaiagoddesslifestyle.com)
  • 12 It is well established that hypoxia is an important selective force in the evolution of tumor cells, 13 and elevated expression of the hypoxia-inducible transcription factors HIF-1 and HIF-2 has been documented in several human cancers. (haematologica.org)
  • The term is entrenched in multiple languages by now (e.g. https://en.wikipedia.org/wiki/List_comprehension ). (python.org)
  • Regarding 'list builder' one could argue that it would just add more confusion, since there's already an unrelated Builder Pattern ( https://en.wikipedia.org/wiki/Builder_pattern ) commonly used in Java. (python.org)
  • According to https://en.wikipedia.org/wiki/List_comprehension#History , the term's known from at least 1977 and comes from such influential languages as NPL, Miranda and Haskell. (python.org)
  • GE researchers, scientists and engineers are widely published in academic journals. (ge.com)
  • Conclusions Hypoxia-inducible factor-2 is a newly identified regulator of CXCL12 expression in multiple myeloma plasma cells and a major contributor to multiple myeloma plasma cell-induced angiogenesis. (haematologica.org)
  • Thus, the expression a += b is equivalent to a = a +b. (adobe.com)
  • Historically, there are several syntax variants for expressions used to express a condition in the different modules of the Apache HTTP Server. (apache.org)
  • That's accurate because the common part with the distinctive syntax -- which is the thing referred to when addressing them all -- effectively _is_ a generator expression (the syntax differences in the leading term are insignificant), what wraps it is of no concern. (python.org)
  • Design and Methods The expression of hypoxia-inducible factor protein was examined in patients' bone marrow biopsy specimens using immunohistochemistry. (haematologica.org)
  • This page covers the very basics of understanding, creating and using regular expressions ('regexes') in Perl. (metacpan.org)
  • Check if a product update expression is statically well-formed. (utexas.edu)
  • Check if a strict binary expression is well-formed. (utexas.edu)
  • Check if an ordering expression is well-formed. (utexas.edu)
  • Check if a division or remainder expression is well-formed. (utexas.edu)
  • Check if an addition, substraction, or multiplication expression is well-formed. (utexas.edu)
  • Check if a less-than expression is well-formed. (utexas.edu)
  • Check if a less-than-or-equal-to expression is well-formed. (utexas.edu)
  • Targeted restoration of CREB expression selectively into the LA of CREB-deficient mice is sufficient to fully restore auditory fear conditioning. (nature.com)
  • The restricted pattern of Kv2.2 expression persists in Kv2.1-KO mice, suggesting distinct cell- and layer-specific functions for these two highly related Kv2 subunits. (jneurosci.org)
  • Join Maria Marshall and Megwyn White as they discuss embodiment and haptic body influence in human expression. (gaiagoddesslifestyle.com)
  • We aimed for addressing the role of FasL expression in human intervertebral disc degeneration (IDD) and immune privilege in terms of the interaction between NP cells and immunocytes via the FasL-Fas machinery. (medsci.org)
  • Our study demonstrated that FasL expression tends to decrease in degenerated discs and FasL plays an important role in human disc immune privilege, which might provide a novel target for the treatment strategies for IDD. (medsci.org)
  • The team at GE Research is actively working on video analytics for hospital room monitoring, activity analysis for streets and the inference of social behavior such as rapport and trust for groups of individuals. (ge.com)
  • Many lessons can be learned from the Gaia mission where DPAC (the Data Processing and Analysis Consortium) was responsible for the processing of Gaia's data and producing the Gaia Catalogue. (lu.se)
  • Effect of silymarin on the relative gene expressions of some inflammatory cytokines in the liver of CCl 4 -intoxicated male rats. (bvsalud.org)
  • It is envisioned that similar structures to DPACE will be used and, to begin with, there will be an overlap with people from Gaia. (lu.se)
  • How to split_and_pad string to n-th chars pieces with one regular expression? (perlmonks.org)
  • Yes - stop trying to do this in a single regular expression. (perlmonks.org)
  • We are looking into our implementation of the Speech and Expression policy and relevant guidelines on tabling in the weeks ahead," said Olson. (thefire.org)
  • The purpose of this study was to survey metalloproteinase expression in the supporting ligaments of the GE junction. (sages.org)
  • The aim of this study is to learn if rat BMSC express brain-derived neurotrophic factor (BDNF) and glia-derived nerve factor (GDNF) and determine if this expression varies according to the number of culture passages. (sld.cu)
  • In both cases, the value of i becomes 8.These operators cannot be used with expressions that involve functions, as in f().a. (adobe.com)
  • Here we collect science cases and expressions of interest in GaiaNIR. (lu.se)
  • Match the type(s) of an expression to some optional target type(s). (utexas.edu)
  • The GE doesn't 'build' generators, it's a generator itself. (python.org)
  • Using these variables may cause the header name to be added to the Vary header of the HTTP response, except where otherwise noted for the directive accepting the expression. (apache.org)
  • Align bound variables to their expressions. (utexas.edu)
  • The variety of skills from across GE Research that have been leveraged for this project include computer vision, machine learning, statistics, software design and optical system engineering. (ge.com)
  • The team at GE Research has had a number of breakthroughs in video analytics. (ge.com)
  • While the mechanisms responsible for aberrant plasma cell expression of CXCL12 remain to be determined, studies in other systems suggest a role for hypoxia and hypoxia-inducible transcription factors. (haematologica.org)
  • Prolonged exposure to hypoxia strongly up-regulated CXCL12 expression in multiple myeloma plasma cells and hypoxia-inducible factor-2 was found to play a key role in this response. (haematologica.org)
  • We are the first group to demonstrate the ability to infer group social states such as trust and rapport - this was using the GE Sherlock system funded by DARPA. (ge.com)
  • Various levels of the expression of FasL have been noted in both degenerative and non-degenerative NP [ 21 - 23 ]. (medsci.org)
  • Complex expressions have multiple operators and operands. (adobe.com)
  • Over-expression of hypoxia-inducible factor in multiple myeloma plasma cells strongly induced in vivo angiogenesis, and administration of a CXCL12 antagonist decreased hypoxia-inducible factor-induced angiogenesis. (haematologica.org)
  • Inadequate hepcidin expression signals for excessive iron absorption from the diet and iron deposition in tissues, causing multiple organ damage and failure. (medscape.com)
  • The simplest expression consists of a single operand with no operators. (adobe.com)
  • Tungsten carbide-cobalt nanoparticle induced miR-21 expression and PDCD4 inhibition in JB6 cells involves a ROS-mediated ERK pathway. (cdc.gov)
  • However, any expression that equates to an imaginary number, such -1^.5 results in the string '-1. (adobe.com)