• GPx-1, SOD-1, and catalase mRNA expression were lower in TA muscles of aged supplemented animals. (cdc.gov)
  • A significant increase in the activities and mRNA expression levels of SOD, CAT, GPx and GRD was shown. (uwi.edu)
  • Genetic analysis revealed the presence of an ecotropic proviral insertion within rhe first intron of the gene encoding apoptosis-inducing factor (AIF) that results in a dramatic reduction in expression. (the-scientist.com)
  • IL-1β secreted by TAMs activates SOD2 and inhibits CAT to modulate intracellular ROS levels, thereby inducing ICAM1 expression. (jci.org)
  • Three-dimensional protein structures of the peroxidated catalase intermediates are available at the Protein Data Bank. (wikipedia.org)
  • Recombinant expression of proteins of interest in Escherichia coli is an important tool in the determination of protein structure. (iucr.org)
  • These data indicate that this eukaryotic cell-free expression system has a high success rate and that the addition of specific reagents can increase the yield of soluble protein. (iucr.org)
  • Protein aggregation remains a significant problem in E. coli expression systems. (iucr.org)
  • Conversely, HRS decreased Bcl2-associated X protein expression, cleaved caspase-3, and oxidant-stress product malondialdehyde (MDA) in a Sirt1-dependent manner. (arvojournals.org)
  • The mRNA and protein expression levels of FOXA2 were determined by reverse transcription‑quantitative PCR and western blotting, respectively. (spandidos-publications.com)
  • Western blotting was performed to examine the protein expression levels of endoplasmic reticulum stress (ERS)‑associated factors. (spandidos-publications.com)
  • investigated the fungus at the level of gene expression, and performed proteome-level studies ( Yajima and Kav, 2006 ). (frontiersin.org)
  • One important strategy for studying these dynamic but highly regulated host defenses is to observe gene expression patterns in the host 5 . (nature.com)
  • Our results suggest that the association of low/moderate intake of alcohol beverages, with nutraceutical-proven effectiveness, and ethanol, in association with a Mediterranean diet, could determine a reduction of atherosclerosis risk onset through a positive modulation of antioxidant gene expression helping in the prevention of inflammatory and oxidative damages. (whiterose.ac.uk)
  • Gene expression data reported significantly upregulation of apoptotic genes. (edu.sa)
  • The data show that endogenous levels of H2S and ABA in maize seedlings could be mutually induced by regulating their metabolic enzyme activity and gene expression under non-heat stress (non-HS) and HS conditions. (bvsalud.org)
  • In this study root-irrigation with 0.15 mM sodium nitroprusside (SNP, NO donor) up-regulated gene expression of L-CYSTEINE DESULFHYDRASE1 (LCD1), activities of L-cysteine desulfhydrase (LCD) and D-cysteine desulfhydrase (DCD), as well as an endogenous H2S level, compared to control seedlings. (bvsalud.org)
  • NaHS had no significant effect on gene expression and activity of nitrate reductase (NR, a NO candidate producing enzyme). (bvsalud.org)
  • catalase functional activity in lysates was determined using a H 2 O 2 activity assay. (bmj.com)
  • Catalase is a common enzyme found in nearly all living organisms exposed to oxygen (such as bacteria, plants, and animals) which catalyzes the decomposition of hydrogen peroxide to water and oxygen. (wikipedia.org)
  • While the complete mechanism of catalase is not currently known, the reaction is believed to occur in two stages: H2O2 + Fe(III)-E → H2O + O=Fe(IV)-E(.+) H2O2 + O=Fe(IV)-E(.+) → H2O + Fe(III)-E + O2 Here Fe()-E represents the iron center of the heme group attached to the enzyme. (wikipedia.org)
  • Therefore, we concluded that arbuscular mycorrhizal fungi (especially P. indica ) mainly induced the expression of antioxidant enzyme genes, depending on the fungal species, and thus mitigated oxidative damage for higher cold resistance in inoculated plants. (techscience.com)
  • Furthermore, CagA-positive strains are known to induce the expression of a DNA-editing enzyme, which leads to accumulation of mutations in the tumor suppressor p53. (medscape.com)
  • The expression levels of LoCAT 1 in roots and stems of L. olgensis after the treatment of NaCl were down-regulated, with the lowest expression at 12 h. (nefu.edu.cn)
  • The expression levels of LoCAT 1 in roots and stems of L. olgensis after the treatment of PEG 6000 were significantly inhibited in the early stage and then up-regulated. (nefu.edu.cn)
  • Some humans have very low levels of catalase (acatalasia), yet show few ill effects. (wikipedia.org)
  • In contrast, the levels of SOD, and catalase activities significantly decreased after treatment. (edu.sa)
  • In addition, inoculation of two mycorrhizal fungi under cold stress significantly increased the relative expression levels of PtPOD and PtF-SOD in leaves, P. indica up-regulated the expression levels of PtCu/Zn-SOD in leaves, and D. versiformis also induced the expression levels of PtMn-SOD and PtCAT1 in leaves. (techscience.com)
  • Cloning, expression, purification and ch. (agu.edu.tr)
  • Cloning and Expression Analysis of Catalase Gene( LoCAT 1) from Larix olgensis [J]. Bulletin of Botanical Research, 2019, 39(4): 539-546. (nefu.edu.cn)
  • To examine the morphological effects of catalase gene transfer in modulation of H 2 O 2 induced injury, transduced corneas were maintained in ex vivo culture and challenged with H 2 O 2 . (bmj.com)
  • 2007). Modulation of Frankia alni ACN14a oxidative stress response: Activity, expression and phylogeny of catalases . (up.pt)
  • However, "Copper deficiency can lead to a reduction in catalase activity in tissues, such as heart and liver. (wikipedia.org)
  • The present study was performed to compare the expression of Foxo3a in periapical granulomas and healthy gingival tissues. (go.jp)
  • In order to know about genes of Larix olgensis catalase and determine the expression characteristics in different organs of L. olgensis under different stresses, a CAT 1 gene was cloned based on specific primers designed according to the CAT 1 gene sequences from transcriptome database of L. olgensis , named LoCAT 1. (nefu.edu.cn)
  • In light-damaged retinas, 5 days of HRS treatment increased Sirt1 expression, mitigated a- and b-wave amplitude reduction, and decreased the reduction of outer nuclear cell layers. (arvojournals.org)
  • Characterization of miRNA expression profile provided support for AR , PPAR, retinoic acid signaling and inflammation in miniaturized hair. (nature.com)
  • However, lack of expression and insolubility remain significant challenges to the expression and crystallization of these proteins. (iucr.org)
  • Significant upregulation of catalase (CAT) was observed only after RW. (whiterose.ac.uk)
  • Foxo3a was expressed in 82.1%, 78.3%, and 77.5% of neutrophils, T lymphocytes, and B lymphocytes, respectively, and statistical analysis using the Kruskal-Wallis test followed by the Steel-Dwass test showed no significant difference of Foxo3a expression among the three cell types. (go.jp)
  • Catalase activity increased with supplementation in the YA and aged animals. (cdc.gov)
  • There is extensive literature on the variables leading to insoluble recombinant expression of proteins. (iucr.org)
  • A recombinant adenovirus vector (AdCL) was used to transfer human catalase cDNA into EC of whole thickness rabbit corneas ex vivo. (bmj.com)
  • APX activities and the relative expression of APX were also stimulated in grafted seedlings, although their changes were not completely consistent. (tubitak.gov.tr)
  • Macrophage secretion of IL-1β was found to induce tumor expression of ICAM1. (nih.gov)
  • The pH optimum for other catalases varies between 4 and 11 depending on the species. (wikipedia.org)
  • The optimum pH for human catalase is approximately 7, and has a fairly broad maximum: the rate of reaction does not change appreciably between pH 6.8 and 7.5. (wikipedia.org)
  • Human catalase forms a tetramer composed of four subunits, each of which can be conceptually divided into four domains. (wikipedia.org)
  • In an anagen human hair follicle PPARγ expression is detected in the mesenchymal DP cells, epithelial cells of the outer root sheath (ORS), inner root sheath and matrix 16 . (nature.com)
  • These in vitro, and their expression in these human tumour virus. (who.int)
  • Expression of vacuolating cytotoxin, which induces inflammatory cytokines, may be associated with more pronounced inflammation and increased propensity to cause disease. (medscape.com)
  • Ex vivo catalase gene transfer can protect EC from death mediated by H 2 O 2 . (bmj.com)
  • In 1937 catalase from beef liver was crystallized by James B. Sumner and Alexander Dounce and the molecular weight was measured in 1938. (wikipedia.org)
  • However, catalase deficiency in mice may increase the likelihood of developing obesity, fatty liver, and type 2 diabetes. (wikipedia.org)
  • In liver, the diet KEECC significantly increased catalase expression compared with diet 0. (stir.ac.uk)
  • Cells co-transfected with an estrogen response element (ERE)-driven luciferase (Luc) reporter gene and an ERalpha- or ERbeta-expression vector were exposed to graded concentrations of ellagic acid. (nutrimedical.com)
  • Yu D L,Wang C L. Progresses in the research of catalase[J]. Chinese Journal of Histochemistry and Cytochemistry,2016,25(2):189-194. (nefu.edu.cn)
  • Enhanced drought and photooxidation tolerance of transgenic tobacco plants overexpressingpea catalase in chloroplasts[J]. Acta Ecologica Sinica,2011,31(4):1058-1063. (nefu.edu.cn)
  • The expression patterns of LoCAT 1 were not exactly similarity among these treatments. (nefu.edu.cn)
  • In 1900, Oscar Loew was the first to give it the name catalase, and found it in many plants and animals. (wikipedia.org)
  • Because of an inherent limitation (extremely low expression), Cys at position 34 of the 3r germ line was replaced by Tyr reaching a good expression yield. (osti.gov)
  • Following incubation with AdCL, catalase expression reached maximum at 5-7 days. (bmj.com)
  • While expression level in leaves was significantly inhibited at 24 h, and then up-regulated, with the highest expression at 96 h. (nefu.edu.cn)