• This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology. (hindawi.com)
  • This notion has been challenged by the discovery of new membrane transport functions, especially those exerted by aquaporins (AQPs), a family of membrane channel proteins widespread in nature [ 10 , 11 ]. (hindawi.com)
  • One of the main traits underlying salt tolerance is the presence of aquaporins (AQPs), a family of proteins that facilitate the movement of water across cell membranes. (botany.one)
  • Aquaporins (AQPs) facilitate transport of water and small solutes across cell membranes and play an important role in different physiological processes in plants. (biomedcentral.com)
  • The present study reports the identification and structural and expression analysis of the AQPs found in the diploid progenitor genomes of A. hypogea i.e. (biomedcentral.com)
  • The global expression profile of AQPs in A. hypogea revealed a similar pattern of AQP expression regardless of the subfamilies or the genomes. (biomedcentral.com)
  • The tissue-specific expression of AQPs suggests an important role in the development and function of the respective organs. (biomedcentral.com)
  • Aquaporins (AQPs) are small (21-34 kD) integral membrane proteins, which form channels facilitating movement of water and other small solutes across the cell membrane. (biomedcentral.com)
  • Intro The flux of water across biological Chlorpheniramine maleate membranes is definitely facilitated by transmembrane protein channels called aquaporins (AQPs). (idplink.net)
  • Constructions of gated AQPs have exposed the molecular details of AQP gating by phosphorylation, pH and Ca2+ for the spinach aquaporin SoPIP2;1 [4] and mechanosensitivity for the candida aquaporin AQY1 [5]. (idplink.net)
  • Aquaporins/major intrinsic proteins (MIP) are a family of water-selective membrane channels. (wikipedia.org)
  • Aquaporins (AQP) are water channel proteins that enable fluid fluxes across cell membranes, important for homeostasis of the tissue environment and for cell migration. (biomedcentral.com)
  • Mammalian aquaporins are a family of 13 classes of intrinsic membrane proteins that assemble as tetramers (~30 kDa per subunit) and are known for their role in fluid homeostasis and trans-membrane transport of water and other small solutes [ 6 , 7 ]. (biomedcentral.com)
  • Dr. King's research focus early in his tenure was the biology of aquaporin water channel proteins in the respiratory tract as well as other tissues. (hopkinsmedicine.org)
  • Takata K, Matsuzaki T, Tajika Y. Aquaporins: water channel proteins of the cell membrane. (benthamscience.com)
  • The main aim of our research is to understand the molecular details and physiological roles of the multitude of water channel-like proteins present in plants and animals. (lu.se)
  • Characterization of RAGE and CK2 Expressions in Human Fetal Membranes. (igred.fr)
  • Purification and characterization of two protein kinases acting on the aquaporin SoPIP2;1. (lu.se)
  • Genomic organization and developmental expression of aquaporin-5 in lung. (hopkinsmedicine.org)
  • Structure and Stability of the Spinach Aquaporin SoPIP2;1 in Detergent Micelles and Lipid Membranes. (lu.se)
  • Aquaporin-7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. (wikipedia.org)
  • Aquaporin-7 (AQP-7) is a protein that in humans is encoded by the AQP7 gene. (wikipedia.org)
  • Protein expression and purification 44 2.3.4. (fu-berlin.de)
  • Protein kinase A type II activation is sufficient to control the cellular localization of the water channel aquaporin-2 in the kidney 72 3.3.1. (fu-berlin.de)
  • In addition, basal expression levels of tight junction protein-1 encoding ZO1 were lower in R91W;Nrl −/− than in wt retinas. (nature.com)
  • Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat. (hopkinsmedicine.org)
  • Expression of Aquaporin-1 water channel protein in mouse erythro-leukemia cells: genetic regulation of corticosteroid and chemical induction. (hopkinsmedicine.org)
  • Quantitative proteomic analysis of the rice genotypes 93-11and Nipponbare after F. fujikuroi infection revealed that the aquaporin protein PIP2-2 might execute bakanae disease resistance. (biomedcentral.com)
  • Overall, the protein regulation trends observed under bakanae disease stress are highly contrasting, and the molecular mechanisms of disease defense are obviously different between 93 and 11 and Nipponbare. (biomedcentral.com)
  • DTL small interference RNAs were used to knock down DTL protein expression. (transhumanist.ru)
  • Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice. (lu.se)
  • Aharon R, Shahak Y, Wininger S, Bendov R, Kapulnik Y, Galili G (2003) Overexpression of a plasma membrane aquaporins in transgenic tobacco improves plant vigour under favourable growth conditions but not under drought or salt stress. (usal.es)
  • Aroca R, Porcel R, Ruiz-Lozano JM (2007) How does arbuscular mycorrhizal symbiosis regulate root hydraulic properties and plasma membrane aquaporins in Phaseolus vulgaris under drought, cold or salinity stresses? (usal.es)
  • Molecular Membrane Biology 2013, 30 (3):246-260. (lu.se)
  • The authors conclude by recommending the GhPIP1;1 and GhTIP2;1 aquaporins located on the plasma and vacuolar membranes, respectively, as reliable markers for identification of cotton genotypes tolerant to salt stress. (botany.one)
  • Aquaporins and Fetal Membranes From Diabetic Parturient Women: Expression Abnormalities and Regulation by Insulin. (igred.fr)
  • and 3) show that the mutual exclusivity of localization is maintained even into end-stage ADPKD. (transhumanist.ru)
  • In the present review, molecular and physiological mechanisms explaining the observed beneficial effects plant derive from the Si supplementations, more particularly in horticultural species have been discussed. (researchsquare.com)
  • In the last 10 years, Roseane has been dedicated to research in transgenic cotton and the prospects of using useful molecular tags as markers in selection procedures for drought and salinity tolerance. (botany.one)
  • Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin-5 (AQP5). (hopkinsmedicine.org)
  • Structural mechanism of plant aquaporin gating. (lu.se)
  • Biochimica et Biophysica Acta (BBA) - Biomembranes 2012, 1818 (3):839-850. (lu.se)
  • To gain a better understanding of the molecular mechanisms of rice bakanae disease resistance, we employed a 6-plex tandem mass tag approach for relative quantitative proteomic comparison of infected and uninfected rice seedlings 7 days post-inoculation with two genotypes: the resistant genotype 93-11 and the susceptible genotype Nipponbare. (biomedcentral.com)
  • Roseane C Santos is an agronomist with an MsC in plant breeding from Rural Federal University of Pernambuco (UFRPE) and a PhD in molecular biology from University of Brasilia (UNB), both in Brazil. (botany.one)
  • Molecular mechanism of contractility 17 1.6.3. (fu-berlin.de)
  • Here, molecular mechanism involved in the Si uptake by root and subsequent transport to areal tissues is also illustrated. (researchsquare.com)
  • However, Si uptake mechanism at molecular level poorly studied in horticulture crops. (researchsquare.com)
  • In humans, thirteen members of the AQP family (AQP0-12), with delicate functional differences, are indicated with different tissue-specific and time-dependent profiles [3]. (idplink.net)
  • Aquaporins are multifunctional water and solute transporters highly divergent in living organisms. (benthamscience.com)
  • 2002). "Human aquaporin adipose (AQPap) gene. (wikipedia.org)
  • Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris. (lu.se)
  • Unexpected complexity of the Aquaporin gene family in the moss Physcomitrella patens. (lu.se)
  • Aquaporins in complex tissues: I. Developmental patterns in respiratory tract and glandular tissue of rat. (hopkinsmedicine.org)
  • Aquaporins in complex tissues: II. (hopkinsmedicine.org)
  • Molecular cloning of a mercurial-insensitive water channel expressed in selected water-transporting tissues. (benthamscience.com)
  • AQP2, PKA types I and II reside on the same intracellular vesicles 74 3.3.3. (fu-berlin.de)
  • 2000. Hypertonic induction of AQP5 expression through an ERK dependent pathway. (hopkinsmedicine.org)
  • The AM symbiosis also improves root hydraulic conductivity under saline conditions, and this may be due to enhanced symplastic and apoplastic radial water flow in rice roots, mediated by the induction of specific aquaporin isoforms and also by the additional water-absorbing surface of AM fungal hyphae. (usal.es)
  • Expression of aquaporins-1 and -2 during nephrogenesis and in autosomal dominant polycystic kidney disease. (transhumanist.ru)
  • Using antibodies against AQP1 and AQP2 , we here show expression of AQP1 and AQP2 in normal human developing and adult kidneys and in autosomal dominant polycystic kidney disease (ADPKD). (transhumanist.ru)
  • Consistent down regulation of AQP expression was found in salt tolerant genotypes, i.e. those that were able to maintain photosynthetic rates under salt stress. (botany.one)
  • Molecular regulation of the PLB-SERCA system 20 1.6.5. (fu-berlin.de)
  • Transcriptional regulation of aquaporins in accessions of Arabidopsis in response to drought stress. (lu.se)
  • AQP1 knockout mouse models of human cancers showed marked inhibition of tumor-induced angiogenesis, and in pre-clinical studies of colon adenocarcinomas, forced over-expression of AQP1 was shown to increase angiogenesis, invasion and metastasis. (biomedcentral.com)
  • Expression of AQP1 in cell lines was assessed by quantitative (q) PCR, western blot and immunofluorescence, while expression of AQP1 in human colon tumour tissue was assessed by immunohistochemistry. (biomedcentral.com)
  • 0.0001) treated with 160 or 320 μM AqB013 respectively, whereas there was no effect on migration of HCT-116 cells with low AQP1 expression. (biomedcentral.com)
  • Aquaporin-1 ( AQP1 ), located in proximal tubules (PT) and descending thin limbs of Henle ( DTL ), and aquaporin-2 ( AQP2 ), located in collecting ducts (CD), are channels involved in water transport across renal tubule epithelia. (transhumanist.ru)
  • Western blot analysis showed maximal expression of AQP1 and AQP2 in normal adult kidneys, lower levels in fetal kidneys, and decreases associated with degree of cystic progression in ADPKD. (transhumanist.ru)
  • Reconstitution of water channel function and 2D-crystallization of human aquaporin 8. (lu.se)
  • High-resolution x-ray structure of human aquaporin 5. (lu.se)
  • Frontiers in Plant Science 2012, 3 . (lu.se)
  • The TIP3s showed seed-specific expression while the NIP1s' expression was confined to roots and root nodules. (biomedcentral.com)
  • Screening programs have helped with early diagnosis and intervention, but for those not participating in such programs some 12-25 % of CRC patients still present with advanced (stage IV) disease [ 3 ]. (biomedcentral.com)
  • Professor, Dept of Molecular Genetics, University of Toronto. (lu.se)
  • In addition we have recently started to explore the structure and molecular function of pain receptors from animals, i.e. transient receptor potential (TRP) ion channels, and their activation by temperature and various ligands. (lu.se)
  • Aquaporin-7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. (wikipedia.org)
  • Analysis of RNA-seq data from A. hypogea revealed a similar expression pattern for the different AQP paralogs of AA and BB genomes. (biomedcentral.com)
  • Further analysis showed that a noticeable aquaporin, PIP2-2, was sharply upregulated with a fold change (FC) of 109.2 in 93-11, which might be related to pathogen defense and the execution of bakanae disease resistance. (biomedcentral.com)
  • Blue light exposure of the R91W;Nrl −/− mouse could therefore be used to study molecular events preceding edema formation in a cone-rich environment, and thus potentially help to develop treatment strategies for edema-based complications in macular degenerations. (nature.com)
  • In our previous study, the upregulation of DTL expression in aggressive HCC correlated positively with tumor grade and poor patient survival. (transhumanist.ru)
  • He was elected to the American Society for Clinical Investigation in 2006 for work on aquaporin water channels. (hopkinsmedicine.org)
  • After the stress treatment, the authors conducted measurements of leaf gas exchange and collected samples for molecular analyses. (botany.one)
  • Substances for treatment of IMCD cells 47 2.5.3. (fu-berlin.de)