GenesRegulationProteinsZic1RegulateDlx1EmbryosPolyclonalDifferentiationPhosphorylationPromoterChromatinNucleusCellsFibroblast growthDevelopmentalMRNA expressionEctopic expressionTranscriptional factorsRegulators of gene expressionPatternsEmbryoEctodermKnockdownPolymeraseXfoxi1aColorectal CancerCoordinateNeural plateReceptorGene expression profilesSuperfamilyPluripotencyDistinct expressionEctodermalCellEmbryonicSignalingProtein expressionToothSox2
Genes28
- Underlying the development of neural crest is a gene regulatory network, described as a set of interacting signals, transcription factors, and downstream effector genes that confer cell characteristics such as multipotency and migratory capabilities. (wikipedia.org)
- In coherence with this observation, the promoter region of slug (a neural crest specific gene) contains a binding site for transcription factors involved in the activation of Wnt-dependent target genes, suggestive of a direct role of Wnt signaling in neural crest specification. (wikipedia.org)
- [ 4 ] The Hox genes, well described as the master regulators of development, encode a set of transcription factors that specify the identity of particular segments during embryogenesis. (medscape.com)
- showed that knocking out Mage-D1 can induce the expression of autophagy-related genes by enhancing the activity and differentiation of osteoclasts, thereby accelerating the process of periodontitis 23 . (researchsquare.com)
- This plethora of Hox protein-protein interactions clearly points to a Hox-driven transcription process in which every Hox homeoprotein could selectively recruit GTFs to achieve specificity and activate or repress target genes during Drosophila development, although the precise molecular mechanisms remain elusive [ 25 ]. (biomedcentral.com)
- Background: HOX genes encode a family of homeodomain-containing transcription factors involved in the determination of cell fate and identity during embryonic development. (123dok.net)
- 25 The downstream target genes of MAPK signaling cascades comprise of the differentiation related transcription aspects Jun ATF2/AP1, C/EBPB and Egr one, which are known to get necessary for myeloid differentiation. (chk1inhibitor.com)
- We established at mRNA level the expression of 84 genes partici pating inside the MAPK signaling network and cell cycle regulation employing Human MAP kinase RT2 Profile PCR Array. (chk1inhibitor.com)
- The main ity of genes studied enhanced their expression in 40AF cells, and the 27 genes upregulated more than 2 fold, 10 with statistical significance, are listed in Table one. (chk1inhibitor.com)
- In this review, we centered on some immune linked genes and analyzed their expressions while in the different developmental phases and sexes. (chk1inhibitor.com)
- N. lugens PGRP and GRP genes showed much higher expression levels in male adults than in female grownups. (chk1inhibitor.com)
- These genes also had relatively large expression ranges in 2nd instar and/or 5th instar nymphs, even though extremely minimal levels were found in eggs. (chk1inhibitor.com)
- Similarly, N. lugens CLIP genes also had substantially high expression levels in male grownups when when compared with the female adults. (chk1inhibitor.com)
- A number of immune re sponsive effector genes exhibited distinctive expression patterns. (chk1inhibitor.com)
- Using single-cell RNA-sequencing data, we examined the expression profiles of Sox genes in the mouse incisor dental pulp. (ehu.eus)
- We found that in several MSCs, Sox genes co-expressed with regulatory genes such as Sp7 , Satb2 , Msx1 , Snai2 , Dlx1 , Twist2 , and Tfap2a . (ehu.eus)
- We also show that Dlx and Smad proteins localize to promoters/enhancers of a number of common telencephalic genes in vivo and that Smad proteins co-activate transcription with Dlx family members, except with certain mutated human DLX proteins identified in autistic individuals. (biomedcentral.com)
- Within this region, their expression overlaps with that of Gad65 and Gad67 , genes encoding different forms of the rate-limiting enzyme required for production of GABA from glutamate. (biomedcentral.com)
- Although the etiology of dental agenesis The association between AXIN2 and CRC involves defects in the involved genetic and environmental factors, the genes more canonical WNT signaling pathway, which regulates and coordi- frequently associated with hypodontia in different populations are nates the AXIN complex for the degradation of β-catenin under 2,3 AXIN2, MSX1, PAX9, EDA, and WNT10. (sagepub.com)
- regulating the expression of target genes. (sagepub.com)
- Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. (cusabio.cn)
- Dr MacKenzie graduated from Strathclyde University with a 2.1 degree in Molecular and Cell Biology in 1988 and went on to do a PhD in molecular embryology under the supervision of Prof Paul Sharpe at the Unversity of Manchester where he studied the expression of the Msx1 and Msx2 genes in the craniofacial region and dentition of the developing mouse embryo. (elsevierpure.com)
- Dr MacKenzie obtained his PhD in 1992 and went on to do his first post-doc at the MRC Human Genome Unit at the Western General Hospital in Edinburgh under the leadership of Prof Robert Hill where he undertook the development of gene knockout models of the Msx1 and Msx2 genes in mice. (elsevierpure.com)
- My research interests focus around the effects of non-coding disease associated polymorphisms on the activity of highly conserved enhancer elements that control the tissue specific expression of genes known to be important in health. (elsevierpure.com)
- Instead, my lab has relied on the hypothesis that because the cell specific expression of genes in regions of the brain such as the hypothalamus has been so highly conserved between species so too have the enhancer regions which support this expression. (elsevierpure.com)
- Proteína homeótica y factor de transcripción que se localiza en el núcleo celular donde activa la expresión de genes tiroideos específicos como el de la TIROGLOBULINA y el RECEPTOR DE TIROTROPINA. (bvsalud.org)
- A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. (bvsalud.org)
- Dentro de esta revisión se describe la fuerte asociación entre las fisuras orales y las mutaciones de genes Msx1, sonic hedgehog, proteínas morfogenéticas óseas y factor de crecimiento fibroblástico durante la migración de las células de la cresta neural y la modelación y formación del paladar. (bvsalud.org)
Regulation9
- Further studies confirmed that p75NTR participates in the regulation of tooth development maybe by changing the activity of the key factor distal-less homeobox/msh homeobox (Dlx/Msx), and melanoma-associated antigen D1 (Mage-D1) seems to be play a role in the differentiation and mineralization of EMSCs 5 , 6 . (researchsquare.com)
- There has been one previous report showing that overexpression of Sirt6 in aged human dermal fibroblasts could improve iPS generation via regulation of miR-766 transcription [ 19 ]. (biomedcentral.com)
- Taken jointly, our information indicated that the actual regulation of Msx1 through BMP4/pSmad1/5 signaling is mediated through importin7 within mouse button dental care mesenchymal tissue.Cytokines communicate carefully with each other and also enjoy a crucial role in the continuing development of sepsis. (microtubule-signal.com)
- data indicate that linc00598 plays an important role in cell cycle regulation and proliferation through its ability to regulate the transcription of CCND2. (cusabio.cn)
- Regulation of Xfoxi1a expression by Bmp and Wnt signals. (xenbase.org)
- However, Dr MacKenzie then went on to develop an understanding of the tissue-specific regulation of the Msx1 gene using transgenic mouse embryos. (elsevierpure.com)
- We will focus particularly on the roles of a tumor suppressor, neurofibromin 2 (NF2), whose expression is not only dependent on compartment-specific transcription factors, but is also subject to regulation by a Hippo-Yap feedback signaling circuit. (molcells.org)
- Successful differentiation is guided in large part by epigenetic reprogramming and regulation of critical gene expression patterns. (biomedcentral.com)
- Proteins transcribed from the E1B region of ADENOVIRUSES which are involved in regulation of the levels of early and late viral gene expression. (nih.gov)
Proteins12
- As master transcriptional regulators, Hox proteins recognize DNA through the homeodomain (HD) and interact with a multitude of proteins, including general transcription factors and other cofactors. (biomedcentral.com)
- Of particular interest are the protein interactions that occur between Hox proteins and general transcription factors (GTF) from the RNA Pol II basal transcription machinery. (biomedcentral.com)
- Here, we focused on the interplay between Antp and the basal transcription machinery and show the direct interaction of Antp with TBP through the poly-glutamine (PolyQ) regions of both proteins. (biomedcentral.com)
- Polycomb group (PcG) proteins are key regulators of gene expression and developmental programs via covalent modification of histones, but the factors that interpret histone modification marks to regulate embryogenesis are less studied. (bvsalud.org)
- Bone morphogenetic proteins (BMPs) are highly conserved signaling molecules that are part of the transforming growth factor (TGF)-beta superfamily, and function in the patterning and morphogenesis of many organs including development of the dentition. (edu.au)
- Furthermore, Smad proteins, transcriptional effectors of TGF-β signaling, are co-expressed and physically interact in the basal ganglia with Dlx homeodomain transcription factors, which are critical regulators of the differentiation, migration and survival of telencephalic GABAergic neurons. (biomedcentral.com)
- In that regard, recent studies in non-neural cells have suggested the existence of functional interactions between Dlx proteins and Smad transcription factors, which are critical mediators of transforming growth factor-β (TGF-β) superfamily signaling pathways (Chiba et al. (biomedcentral.com)
- In cells receive the WNT signal, β-catenin is stabilized and joins the addition, AXIN2 has also been independently associated with DNA-bound T-cell factor family of transcription proteins for tooth agenesis and non-syndromic cleft lip palate (NSCLP). (sagepub.com)
- Both CCND1- and CCND2-expressing MM cells arrested in S/G2/M, and did not differ in other cell-cycle proteins or sensitivity to IR.Differential expression of D-cyclin does not appear to affect cell-cycle response to IR, and is unlikely to underlie differential sensitivity to DNA damage. (cusabio.cn)
- To check this hypothesis, we overexpressed inducible types of HES-1 and MSX-1 proteins in mouse ESCs and examined differentiation into Azlocillin sodium salt NC derivatives, including neural, soft muscle tissue, and chondrocyte-like cells, after activation of the transcription elements. (globaltechbiz.com)
- MSY3 (MSY4, YB-2, CSDA, dbpA, ZONAB) is a member of the cold shock domain (CSD) family of proteins also known as Y-box proteins, which are evolutionarily conserved proteins that function as transcription factors and regulators of RNA metabolism and protein synthesis. (biomedcentral.com)
- This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. (cancer-genetics.org)
Zic12
- Morphorgens such as Wnt, fibroblast growth factor (FGF), retinoic acid (RA) and bone morphogenetic protein (BMP) secreted from the paraxial mesoderm and epidermis regulates the expression of a group of transcription factors ( Pax3, Zic1, Msx1 ) whereby defines the boarder of neural crest. (biomedcentral.com)
- Ectopic expression of either Pax3/Zic1 or Snai2/Wnt8 made gastrula explants qualified to produce myogenic differentiation 1 (MyoD) and Endodermin. (globaltechbiz.com)
Regulate5
- Signaling mechanisms mediated by the Transforming Growth Factor-β (TGF-β) superfamily regulate a variety of developmental processes. (biomedcentral.com)
- Mouse somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) by defined factors known to regulate pluripotency, including Oct4, Sox2, Klf4, and c-Myc. (biomedcentral.com)
- Differentiated somatic cells can be reprogrammed into a pluripotent-like state through four defined factors known to regulate pluripotency, including Oct4, Sox2, Klf4, and c-Myc (OSKM) [ 1 , 2 ]. (biomedcentral.com)
- Nonetheless, the precise co-factors which help pSmad1/5 going into the particular nucleus to regulate Msx1 in dental mesenchymal cells remain unknown. (microtubule-signal.com)
- My primary focus has been on the regulatory elements that support the expression of neuropeptides such as Substance-P and Galanin in regions of the nervous system that include the dorsal root ganglia, the hypothalamus and the amygdala where these peptides are known to regulate the inflammatory response, nutrient selection and mood respectively. (elsevierpure.com)
Dlx14
- In vitro, Mage-D1 not only binds to p75 neurotrophin receptor (p75NTR) but also to distal-less homeobox 1(Dlx1) and msh homeobox 1 (Msx1). (researchsquare.com)
- p75NTR, Dlx1, and Msx1 seem to be closely related to the underlying mechanism of Mage-D1 action. (researchsquare.com)
- In agreement with these observations, expression of dominant-negative Smads in the developing basal ganglia phenocopies the cell migration defects observed in Dlx1/2 -deficient mice. (biomedcentral.com)
- Four members of the mouse Dlx protein family (Dlx1, 2, 5 and 6), part of the Antennapedia class of non-Hox homeodomain transcription factors, are expressed in the embryonic subpallium (Panganiban and Rubenstein 2002 ). (biomedcentral.com)
Embryos5
- Ectodermal marker expression in tailbud stage embryos (albino) that had received neural plate grafts (pigmented and/or mycGFP-labeled) into belly ectoderm at stage 13. (xenbase.org)
- After grafting mycGFP-labeled or pigmented ectoderm from various locations and stages into the lateral neural plate border (NB) of stage 12-13 hosts (A,H), expression of panplacodal ( Six1 ), neural crest ( FoxD3 ) or neural ( Sox3 ) markers was analyzed in tailbud stage embryos (B-K). (B′-K′) Sections through grafts. (xenbase.org)
- A-J) Effects of Bmp or Wnt signals on Xfoxi1a expression in the gastrula and neurula were analyzed by injecting pCS2- BMP4 (2.5 pg DNA/cell) (B,G), Chd (50 pg RNA /cell) (C,H), pCS2- Wnt1 (2.5 pg DNA/cell) (D,I) or Dkk1 (125 pg RNA/cell) (E,J) into all the animal blastomeres of eight-cell embryos. (xenbase.org)
- Control embryos are shown in A and F. (K) Gene expression in animal caps injected with RNAs encoding Chd (200 pg) or Chd (200 pg) +Bmp4 (20 pg) was analyzed by RT-PCR. (xenbase.org)
- eph dsRNA was injected into syncytial stage embryos to perturb eph expression at the larval time points relevant to axon targeting in the adult visual system. (sdbonline.org)
Polyclonal1
- Nevertheless, many experimental techniques are designed inside a nonregulated style, precluding evaluation at different period factors during NC Rabbit Polyclonal to C-RAF induction. (globaltechbiz.com)
Differentiation5
- SOX transcription factors play key roles in cell differentiation and cell fate determination during development. (ehu.eus)
- Here we show that components of both bone morphogenetic protein/growth differentiation factor and TGF-β/activin/Nodal branches of TGF-β superfamily signaling are expressed in the developing subpallium. (biomedcentral.com)
- Manifestation of Hes1 and Msx1 in Wild-type Sera Cells in Pluripotent Circumstances and after NC Differentiation To investigate the part of and in the differentiation of mESCs into neural crest cells, we utilized the stromal cell-inducing activity of Pre-adipose 6 (PA6) cells for 5 times [17], accompanied by the addition of BMP4, which commits cells to differentiate into NC derivatives [6]. (globaltechbiz.com)
- Knocking down Akt expression increased the amount of dephosphorylated MSY3 and reduced myogenin expression and muscle differentiation. (biomedcentral.com)
- This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. (cancer-genetics.org)
Phosphorylation3
- BMP signaling in the rudimentary maxillary incisor, assessed by expressions of Msx1 and Dlx2 and the phosphorylation of Smad protein, was significantly enhanced. (edu.au)
- Skeletal muscle and myogenic C2C12 cells were used to study the effects of MSY3 phosphorylation in vivo and in vitro on its sub-cellular localization and activity, by blocking the IGF1/PI3K/Akt pathway, by Akt depletion and over-expression, and by mutating potential MSY3 phosphorylation sites. (biomedcentral.com)
- Furthermore, forced expression of Akt in adult skeletal muscle induced MSY3 phosphorylation and myogenin derepression. (biomedcentral.com)
Promoter3
- These novel interactions open the possibility to analyze promoter function and gene expression to measure transcription factor binding dynamics at target sites throughout the genome. (biomedcentral.com)
- Finally, ChIP along with Re-ChIP analysis revealed IPO7 helped the particular employment of pSmad1/5 for the Msx1 promoter. (microtubule-signal.com)
- The Y-box protein MSY3/Csda represses myogenin transcription in skeletal muscle by binding a highly conserved cis-acting DNA element located just upstream of the myogenin minimal promoter (myogHCE). (biomedcentral.com)
Chromatin2
- Histone post-translational modifications (PTMs) modulate the chromatin landscape by changing overall charge and by recruiting chromatin modifier enzymes, thereby facilitating gene expression/repression and DNA repair. (biomedcentral.com)
- As a pluripotent and dynamic cell population, the cranial neural crest undergoes vast transcriptional and epigenomic alterations throughout the formation of facial structures pointing to an essential role of factors regulating chromatin state or transcription levels. (bvsalud.org)
Nucleus2
- Once activated, R-Smads accumulate in the nucleus where they associate with Smad4, a common partner for all R-Smads, to form transcription complexes. (biomedcentral.com)
- While Akt over-expression rescued myogenin expression in MSY3 overexpressing myogenic cells, ablation of the Akt substrate, (Ser126 located in the MSY3 cold shock domain) promoted MSY3 accumulation in the nucleus and abolished this rescue. (biomedcentral.com)
Cells8
- The purpose of this study was to investigate the expression pattern of Mage-D1 in rat tooth germ development and its differential mineralization ability to ectomesenchymal stem cells (EMSCs), and to explore its potential mechanism. (researchsquare.com)
- Finally, we cultured human glioma cancer stem cells (GCSCs) from patient specimens found with high expression of HOXD9 in GCSCs compared with normal astrocyte cells and neural stem/progenitor cells (NSPCs). (123dok.net)
- Conclusions: Our results suggest that HOXD9 may be a novel marker of GCSCs and cell proliferation and/or survival factor in gliomas and glioma cancer stem-like cells, and a potential therapeutic target. (123dok.net)
- My approach to identifying and characterising enhancer regions is different to the "mainstream methods" currently favoured which utilise large scale whole genome analysis to detect enhancers using ChIP-seq (H3K4me, H3K27ac, transcription factor binding etc) and DNAse hypersensitivity analysis in cancer cells. (elsevierpure.com)
- We found that transcripts were increased in MGR cells, whereas coactivation of HGR+MGR caused a significant increase in (-found that some of the transcription factors associated with the development of the NC are coexpressed with pluripotency factors at the blastula and gastrula stages. (globaltechbiz.com)
- This study highlights a previously undescribed Akt-mediated signaling pathway involved in the repression of myogenin expression in myogenic cells and in mature muscle. (biomedcentral.com)
- The growth of individual tissue compartments is mainly related to the proliferation of the cells that comprise that compartment, whereas intercellular communication mediated by various morphogens and growth factors is responsible for coordination of growth between neighboring tissue compartments. (molcells.org)
- IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression. (harvard.edu)
Fibroblast growth1
- Families of molecules such as those of Wnt, Hh (hedgehog), FGFs (Fibroblast Growth Factor) and BMPs (Bone Morphogenetic Protein, of TGFßs - Transforming Growth Factor family) have been identified, in different proportions and sites, with tissue-specific and stage-specific functions 1-2 . (bvsalud.org)
Developmental1
- This essay recommends a new brain stem nomenclature based on developmental gene expression, progeny analysis, and fate mapping. (edu.au)
MRNA expression6
- Die erste mRNA-Expression, die sich unter dem PDLLA-BMP-2-Einfluss gegenüber der Kontrollgruppe abhob, war die des Rezeptors TGFβR1. (fu-berlin.de)
- The present in vitro study aimed to analyse the effect of PDLLA-BMP-2-coated titanium Kirschner wires on mRNA expression patterns of human primary osteoblasts. (fu-berlin.de)
- The stimulating effect of PDLLA coated titanium Kirschner wires on mRNA expression levels was observed as from investigation day 10, whereas this effect occurred in the PDLLA-BMP-2 group as from day five. (fu-berlin.de)
- The first instance of mRNA expression observed under the influence of PDLLA-BMP-2 was on the TGFβR1 receptor. (fu-berlin.de)
- An intense stimulation of mRNA-expression was detectable at day 10 in both experimental groups. (fu-berlin.de)
- Substantially increased mRNA expression levels in the PDLLA group were observed for the transcription factor MSX1, ECM protein COLL12A1, biglycan, MMP2 proteinase and growth factor FGF2. (fu-berlin.de)
Ectopic expression2
- We further show that Dlx3 and GATA2 are required cell-autonomously for panplacodal and epidermal marker expression in the non-neural ectoderm , while ectopic expression of Dlx3 or GATA2 in the neural plate suppresses neural plate , border and crest markers. (xenbase.org)
- Disruption of this graded pattern of Eph activity by double-stranded RNA interference or by ectopic expression of wild-type or dominant-negative transgenes perturbs the establishment of medulla cortical axon topography. (sdbonline.org)
Transcriptional factors1
- Particularly, by performing transcriptome analysis, we observed that several pluripotent transcriptional factors increase in knockout cell line, which explains the underlying loss of pluripotency in Sirt6-null iPS-like cell line. (biomedcentral.com)
Regulators of gene expression1
- Epigenetic mechanisms are one of the essential regulators of gene expression which do not involve altering the primary nucleotide sequence. (ehu.eus)
Patterns1
- Collectively, the distinct expression patterns of the SOX transcription factors suggest that they play essential regulatory roles in directing. (ehu.eus)
Embryo2
- Following knockdown of Dnmt1 and Dnmt3a in zygotes, expression levels of Cdx2 in the trophectoderm and Nanog in the inner cell mass were measured, as well as p62 levels, reactive oxygen species (ROS) production, and apoptosis levels after 96 hours in embryo culture. (ehu.eus)
- In the embryo, zygotic transcription of Eph is confined to the nervous system. (sdbonline.org)
Ectoderm3
- Researchers have demonstrated that the expression of dominate-negative Fgf receptor in ectoderm explants blocks neural crest induction when recombined with paraxial mesoderm. (wikipedia.org)
- Interestingly, before the establishment of the preplacodal region, Xfoxi1a expression is detected in the entire cephalic non-neural ectoderm at the mid- and late gastrula stages. (biologists.com)
- The early Xfoxi1a expression in the anteroventral ectoderm is dependent on Bmp signals and suppressed by Wnt signals. (biologists.com)
Knockdown1
- Next, knockdown involving IPO7 canceled your upregulation associated with Msx1 caused by simply BMP4, whilst overexpression associated with Smad1 could recovery the particular Msx1 expression. (microtubule-signal.com)
Polymerase1
- The expression of circ-JA760602 in AC16 cardiomyocytes subjected to hypoxia was measured by quantitative real-time polymerase chain reaction (qRT-PCR). (ehu.eus)
Xfoxi1a3
- The winged-helix transcription factor Xfoxi1a is one of the earliest markers for the preplacodal region at the mid-neurula stage. (biologists.com)
- Inhibition of Xfoxi1a activities by injection of antisense oligonucleotides leads to suppression of non-CNS ectodermal markers (e.g. keratin ) and expansion of the anterior expression domain of the CNS marker Sox2 . (biologists.com)
- Temporal and spatial expression of Xfoxi1a /b. (xenbase.org)
Colorectal Cancer1
- High CCND2 expression is associated with Metastasis of Colorectal Cancer. (cusabio.cn)
Coordinate1
- Basic helix-loop-helix (bHLH) myogenic regulatory factors coordinate the correct function and organization of many skeletal muscle functions. (biomedcentral.com)
Neural plate1
- Signaling events that establish the neural plate border lead to the expression of a set of transcription factors delineated here as neural plate border specifiers. (wikipedia.org)
Receptor1
- EphA1 mis-expression did not cause neurodegeneration, shorten lifespan or affect memory but flies mis-expressing the wild-type or mutant receptor were hyper-aroused, had reduced sleep , a stronger circadian rhythm and increased clock neuron activity and excitability. (sdbonline.org)
Gene expression profiles1
- Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. (cancer-genetics.org)
Superfamily2
- Together, these results suggest that TGF-β superfamily signaling plays a role in telencephalic GABAergic neuron development through functional interactions with Dlx transcription factors. (biomedcentral.com)
- Importin7 (IPO7) is amongst the critical members of importin β-superfamily, generally responsible for nucleocytoplasmic driving regarding RNAs and meats, which include transcription aspects. (microtubule-signal.com)
Pluripotency1
- The authors propose that the NC factors can also be viewed as pluripotency maintenance factors [21]. (globaltechbiz.com)
Distinct expression1
- The reeler gene showed a distinct expression pattern, together with the maximum transcript amounts staying detected from the 5th instar nymphs followed through the 2nd instar nymphs. (chk1inhibitor.com)
Ectodermal1
- In ectodermal explants, high Activin concentrations induced the expression of Azlocillin sodium salt mesodermal and endodermal markers in the blastula but not gastrula stage. (globaltechbiz.com)
Cell1
- Results: In this study, we found high expression of the HOXD9 gene transcript in glioma cell lines and human glioma tissues by quantitative real-time PCR. (123dok.net)
Embryonic1
- Mouse embryonic fibroblasts isolated from transgenic Oct4-GFP reporter mice with or without Sirt6 were used for reprogramming by Yamanaka factors. (biomedcentral.com)
Signaling1
- When we reviewed pretransplantation factorHD, individual aspects including HCT-CI as well as Ps3 had been from the progression of candidemia, which implies which significantly not well patients together with transplantation-associated complications will build candidemia.Msx1 is vital for your upkeep of the actual odontogenic fate regarding dentistry mesenchymal cellular material, which is regulated simply by BMP/Smad1/5 signaling in a Smad4-independent way. (microtubule-signal.com)
Protein expression2
- Using immunohistochemistry, we observed HOXD9 protein expression in human brain tumor tissues, including astrocytomas and glioblastomas. (123dok.net)
- Scope includes mutations and abnormal protein expression. (cancer-genetics.org)
Tooth1
- Results showed that the expression of Mage-D1 during rat tooth germ development was temporally and spatially specific. (researchsquare.com)
Sox21
- In glioma CSC (GCSC), the expression of some neural stem markers, such as SOX2 and Musa-shi-1, has been reported[6,7]. (123dok.net)