Expression identifies. Medical search. Frequent questions

A human genome microarray identified 9109 genes after removing uniformly expressed genes and excluding samples with many outliers. (medscape.com)
Previous transcriptomic studies have identified individual differential y expressed genes between smokers and non- smokers. (nih.gov)
WGCA), an unsupervised network analysis approach, was applied to identify gene expression clusters and to test the relationship between co-expressed genes and smoking. (nih.gov)
Purpose: We identified differentially expressed genes associated with response to pegylated interferon-α treatment in patients with renal cell carcinoma. (elsevierpure.com)

Using samples heterozygous for transcribed single nucleotide polymorphisms (SNPs), allelic expression profiling is a powerful technique for identifying cis -regulatory variants controlling gene expression. (diabetesjournals.org)
They were able to identify several candidate genes, however, by conducting a less stringent analysis, looking for variants shared among subsets of the patients. (nih.gov)
Candidate avirulence genes were identified by correlating virulence profiles with small variants (SNP and InDel) and CNV, and RNA-seq data of an additional three Pt isolates to validate expression of genes encoding secreted proteins (SPs). (bvsalud.org)
NEW YORK - Researchers at the University of Manchester and the University of Cambridge in the UK have identified 24 genetic variants significantly associated with predisposition to endometrial cancer. (genomeweb.com)
Here, we demonstrate that LSCs, HSCs, and pre-leukemic stem cells can be identified and molecularly profiled by combining single-cell transcriptomics with lineage tracing using both nuclear and mitochondrial somatic variants. (nature.com)

Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer. (nih.gov)
Expression profiling was carried out on samples of 7 benign, 7 LMP and 28 invasive (moderate and poorly differentiated) serous tumors and four whole normal ovaries using oligonucleotide microarrays representing over 21,000 genes. (nih.gov)
In search for subgroups of diffuse large B-cell lymphoma (DLBCL) with different histogenetic origin and prognosis, as has been described by gene expression profiling, we examined tumor specimens from 125 patients with DLBCL, uniformly treated by either cyclophosphamideAdriamycin-vincristine-prednisone or methotrexate, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin in a multicenter trial set by the Nordic Lymphoma Group 1989-1994. (aacrjournals.org)
In a nested case-control study, we evaluated the expression of 56 mRNA molecules from at-arrival blood samples of 234 cattle across seven populations via NanoString nCounter gene expression profiling. (researchsquare.com)
Materials and Methods: We performed expression profiling on renal cell carcinoma specimens isolated from 23 patients with metastatic disease who were subsequently treated with interferon. (elsevierpure.com)

This approach aggregates genes that participate in the same pathways and accounts for the fact that degree of expression of a gene does not necessarily correlate to the strength of its effect. (medscape.com)
These signatures will help identify changes in cellular processes and pathways that are causative of or result from malignant transformation. (nih.gov)
In this study, we performed a pathway analysis by integrating GWAS and gene expression analysis to detect the RA-related pathways. (oncotarget.com)
The integrative analysis identified 28 pathways associated with RA. (oncotarget.com)
Among these pathways, 18 pathways were also found by both GWAS and gene expression analysis, 7 pathways are novel RA-related pathways, such as B cell receptor signaling pathway, Toll-like receptor signaling pathway, Fc gamma R-mediated phagocytosis and so on. (oncotarget.com)
Overall, these findings advance our knowledge on dystonia, linking translational control pathways and calcium physiology to dystonia pathogenesis and identifying potential new pharmacological targets. (jneurosci.org)
OxLDL exposure up-regulated C/EBP-beta expression and increased genomic binding events, most prominently around genes involved in inflammatory response pathways. (ox.ac.uk)

Signatures" derived from host gene expression patterns can distinguish individuals infected with influenza or Staphylococcus aureus from noninfected individuals, according to 2 reports published online January 9, 2013, in PLOS One . (medscape.com)
Given the uncertainty about the relationship between these different forms, we compared their patterns of gene expression. (nih.gov)
Increased expression of complement factor B, pro-inflammatory, and type I interferon-associated mRNA hallmark the at-arrival expression patterns of cattle that develop severe clinical BRD. (researchsquare.com)
Further research is necessary to evaluate these expression patterns in a prospective manner. (researchsquare.com)
2008 However discrepancies between pri-miRNA and mature miRNA abundance suggest that widespread posttranscriptional events also shape miRNA expression patterns in human lymphoma cell lines and mouse main lymphocytes (Thomson et al. (sciencepop.org)
allows display of expression patterns for candidate genes in defined gene linkage loci. (nih.gov)
We identified distinct gene expression programming patterns in endodormancy and ecodormancy that reproducibly occur between different genotypes and species. (frontiersin.org)
Scholars@Duke publication: Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation. (duke.edu)
The team analyzed the patients' blood samples to assess gene signatures, which are patterns that show which genes are switched on and off - information that can be used to identify whether a person has a bacterial or viral infection. (medicalnewstoday.com)

They then categorized the functional impact of each newly identified genetic variant. (nih.gov)
Small variant comparisons between the isolates identified 27-40 candidates and CNV analysis identified 14-31 candidates for each Avr gene , which when combined, yielded the final 40, 64, and 69 candidates for AvrLr1, AvrLr15, and AvrLr24, respectively. (bvsalud.org)
Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding. (ox.ac.uk)

Moreover, gene expression analysis of gastric cancer identified a collection of genes (ITGB5, TYMS, MYB, APOC1, CBX5, PLA2G2A, and KIF20A) whose expression was elevated in gastric tumor tissue and downregulated more than 2-fold by vorinostat treatment in gastric cancer cell lines. (nih.gov)
Identifying tumor antigen specific T cells from cancer patients has been a goal of tumor immunologists for several decades. (bepress.com)
Here we identified a subset of tumor‐infiltrating CD8 T cells (CD8 TIL) characterized by co‐expression of CD103 and CD39 in human solid tumors. (bepress.com)
Using this approach, we identified Dlg7, the homolog of the Drosophila Dlg1 tumor suppressor gene, as downregulated at the early stages of KG1 differentiation. (nih.gov)
Molecular profiles should also aid physicians in identifying the primary tumor sites for cancers of unknown origin at the time of diagnosis. (nih.gov)
Past research indicated a possible role for antigen in the pathogenesis of CLL and identified numerous interactions between tumor cells and the tissue microenvironment. (nih.gov)

In a study published on Monday in the Journal of Medical Genetics , the researchers reported that they identified SNPs in HNF1B, KLF, EIF2AK, CYP19A1, SOX4, and MYC, which are all genes involved in cell survival, estrogen metabolism, and transcriptional control. (genomeweb.com)

The results of this study support the hypothesis that changes to cis -regulation of gene expression are involved in a large proportion of SNP associations with type 2 diabetes susceptibility. (diabetesjournals.org)
Naive T cells with reduced Ago2 and miRNA expression differentiated more readily into cytokine-producing helper T cells suggesting that activation-induced Pamidronate Disodium miRNA down-regulation promotes acquisition of helper T cell effector functions by calming the repression of genes that direct T cell differentiation. (sciencepop.org)
2004 Lineage-restricted transcription Pamidronate Disodium factors chromatin remodeling and posttranscriptional regulation all contribute to the major changes in gene expression that characterize T cell activation and differentiation (Ansel et al. (sciencepop.org)
A set of 63 genes was identified (the AhR gene expression biomarker) that was dependent on AhR for regulation after exposure to TCDD or benzo[a]pyrene and includes the known AhR targets Cyp1a1 and Cyp1b1. (nih.gov)
The use of these alternative promoters enables the regulation of isoform expression pre-transcriptionally. (bioconductor.org)
Here we characterize expression and chromatin state dynamics across three tissues-liver, lung, and kidney-in 47 strains of the Collaborative Cross (CC) mouse population, examining the regulation of these dynamics by expression quantitative trait loci (eQTL) and chromatin QTL (cQTL). (duke.edu)
This analysis demonstrates the complexity of transcriptional and chromatin dynamics and their regulation over multiple tissues, as well as the value of the CC and related genetic resource populations for identifying specific regulatory mechanisms within cells and tissues. (duke.edu)

Therefore, we aimed to selectively analyze and corroborate at-arrival mRNA expression from multiple independent populations of beef cattle. (researchsquare.com)
Subsequent analysis showed that EGFR inhibitor could also lead to both decreased PD-L1 and B3GNT3 mRNA expression. (elsevierpure.com)

A second group of individuals were shown photos and videos of the facial expressions generated in response to the scenarios and asked to match the facial expressions back to the original selection of scenarios. (kcl.ac.uk)
Hence, in addition to the support of the evolutionary hypothesis of the female superiority in detecting facial expressions of emotions, recognition of facial expressions also depend on the time available to correctly identify an expression. (bvsalud.org)
Motors within the skull selectively tug and release cables attached to various locations on the underside of the face, in the same way that muscles beneath the skin of our own faces allow us to switch between different facial expressions. (newatlas.com)
When the computer that controls the robot subsequently analyzed the hours of footage, it utilized an integrated neural network to learn which combinations of "muscle movement" resulted in which facial expressions. (newatlas.com)
See if you can identify the facial expressions that quickly flash across these faces. (paulekman.com)

The purpose of this study was to identify and validate a therapeutic agent which might improve the outcomes for gastric cancer patients in the future. (nih.gov)
We used this profile in the Broad Institute's Connectivity Map analysis to identify candidate therapeutic compounds for gastric cancer. (nih.gov)
We showed that analysis of gene expression signature may represent an emerging approach to discover therapeutic agents for gastric cancer, such as vorinostat. (nih.gov)
Potential targets for therapeutic intervention have been identified. (nih.gov)

To identify inhibitors of Leishmania major and Trypanosoma cruzi PTR1, we combined a rapid-screening strategy using a folate-based library with structure-based design. (rcsb.org)

JSONPath WG S. Gössner, Ed. Internet-Draft Fachhochschule Dortmund Intended status: Standards Track G. Normington, Ed. Expires: 17 October 2023 C. Bormann, Ed. Universität Bremen TZI 15 April 2023 JSONPath: Query expressions for JSON draft-ietf-jsonpath-base-13 Abstract JSONPath defines a string syntax for selecting and extracting JSON (RFC 8259) values from a JSON value. (ietf.org)

We examined genetic nteractions between Delta elp3 and two other HAT mutants, Delta mst2 nd Delta gcn5 and used whole genome microarray analysis to analyze heir effects on gene expression. (diva-portal.org)
EyeBrowse , an eye-centric whole genome browser that integrates all the data on cDNA and expression data as well as disease genes and candidate disease gene regions available for human, mouse, rat, chicken, zebrafish and several other species. (nih.gov)
Plyusnin A , Vapalahti O , Vaheri A . Hantaviruses: genome structure, expression and evolution. (cdc.gov)
Methods: B3GNT3 was identified through transcriptome sequencing and The Cancer Genome Atlas Lung Adenocarcinoma (TCGA-LUAD) database. (elsevierpure.com)
Genome-wide association studies (GWAS) have identified over 40 loci that affect risk of coronary artery disease (CAD) and the causal mechanisms at the majority of loci are unknown. (ox.ac.uk)

Here, we corroborate at-arrival mRNA markers identified in previous transcriptome studies and generate a prediction model to be evaluated in future studies. (researchsquare.com)

In this study, exonic SNPs, suitable for measuring mature mRNA levels and in high linkage disequilibrium with 65 lead type 2 diabetes GWAS SNPs, were identified and allelic expression determined by real-time PCR using RNA and DNA isolated from islets of 36 white nondiabetic donors. (diabetesjournals.org)
A significant allelic expression imbalance (AEI) was identified for 7/14 (50%) genes tested ( ANPEP , CAMK2B , HMG20A , KCNJ11 , NOTCH2 , SLC30A8 , and WFS1 ), with significant AEI confirmed for five of these genes using other linked exonic SNPs. (diabetesjournals.org)

Applicants should propose to employ high-throughput, automated genomics technologies or proteomics technologies to detect, quantitate, and identify alterations of DNA, mRNA, or proteins in tissue specimens or body fluids of cancer patients. (nih.gov)

Lastly, results of a targeted islet expression quantitative trait loci experiment support the AEI findings for ANPEP , further implicating ANPEP as the causative gene at its locus. (diabetesjournals.org)
It is this hypothesis that has led many to conduct expression quantitative trait loci (eQTL) studies, where the disease-associated genotype is correlated with expression of cis -linked transcripts. (diabetesjournals.org)

Conclusions: Our results indicate that the B3GNT3 expression is tightly correlated with PD-L1 expression and EGFR mutation status. (elsevierpure.com)
Conclusions: We have identified 4 genes (3 uncharacterized and 1 known) that may prove useful in predicting response to interferon-α treatment in patients with renal cell carcinoma. (elsevierpure.com)
Whitehead Institute researchers report that common assumptions employed in the generation and interpretation of data from global gene expression analyses can lead to seriously flawed conclusions about gene activity and cell behavior in a wide range of current biological research. (labmanager.com)

Gudmundsson KO, Thorsteinsson L, Sigurjonsson OE, Keller JR, Olafsson K, Egeland T, Gudmundsson S, Rafnar T. Gene expression analysis of hematopoietic progenitor cells identifies Dlg7 as a potential stem cell gene. (nih.gov)
When analyzed in different types of stem cells, Dlg7 expression was detected in purified human bone marrow-derived CD133+ progenitor cells, human mesenchymal stem cells, and mouse embryonic stem (ES) cells. (nih.gov)
While mutational status discriminates between healthy and cancerous cells, gene expression distinguishes stem cells and progenitor cell populations. (nature.com)

This study is the first to develop and apply an integrated framework of gene expression , single nucleotide polymorphism (SNP), insertion/deletion (InDel), and copy number variation (CNV) analysis in a rust fungus and identify candidate avirulence genes . (bvsalud.org)

Identifying signatures of molecular alterations that occur during the initiation, progression, treatment, and recurrence of cancer may provide information that allows physicians to make improved clinical decisions for individual cancer patients. (nih.gov)
RESEARCH OBJECTIVES Background The ultimate goal of identifying molecular signatures of tumors is to develop more effective strategies for management of individual cancer patients. (nih.gov)
These multi-disciplinary teams should propose projects to identify molecular signatures that correlate with clinical parameters or specific stages of the cancer development, or that address questions or needs in clinical cancer research. (nih.gov)
They did, however, identify time-dependent gene-expression signatures associated with certain clusters of genes. (genengnews.com)
By measuring patients' gene expression profiles from blood samples, the team found they could use the previously identified gene signatures to correctly identify patients with flu viruses, rhinovirus, various strep bacteria and other common infections with 87% accuracy. (medicalnewstoday.com)

In disciplines including archaeology, forensic anthropology, bioarchaeology, osteoarchaeology and zooarchaeology, the number of identified specimens (also number of individual specimens or number of individual species), or NISP, is defined as the number of identified specimens for a specific site or skeleton. (wikipedia.org)

Sequence and expression data for human eye tissues and for a wide range of important animal models including mouse and zebrafish. (nih.gov)
This can help identify major differences or similarities among tissues. (nih.gov)
Leveraging overlapping measurements of gene expression and chromatin accessibility on the same mice from multiple tissues, we used mediation analysis to identify chromatin and gene expression intermediates of eQTL effects. (duke.edu)

This article focuses on referring expressions in hierarchically structured domains, exploring the hypothesis that referring expressions can be improved by including logically redundant information in them if this leads to a significant reduction in the amount of search that is needed to identify the referent. (mit.edu)
Generation algorithms are presented that implement this idea by including logically redundant information into the generated expression, in certain well-circumscribed situations. (mit.edu)
The first experiment confirms that human judges have a preference for logically redundant expressions in the cases where our model predicts this to be the case. (mit.edu)

Our work provides a toolkit for investigating taste functions of IRs, defines a subset of these receptors required for carbonation sensing, and illustrates how the gustatory system uses combinatorial expression of sensory molecules in distinct neurons to coordinate behaviour. (nature.com)
Healthy and Treated_1 cattle were similar in terms of gene expression, while Treated_2+ cattle were the most distinct. (researchsquare.com)
Extending these observations we recently employed single cell sequencing to identify a distinct minor subpopulation of activated and proliferating CLL cells in the lymph node microenvironment that interface with the immune milieu, and promote disease progression. (nih.gov)
Most human genes have multiple promoters that control the expression of distinct isoforms. (bioconductor.org)

The observation of altered gene expression after vorinostat treatment may provide the clue to identify the molecular mechanism of vorinostat and those patients likely to benefit from vorinostat treatment. (nih.gov)

Researchers from the Institute of Psychiatry (IoP) at King's College London have, for the first time, identified the facial expression of anxiety. (kcl.ac.uk)
SAGE gene expression data for human retina and RPE through EyeSAGE, a collaboration with researchers at Duke University. (nih.gov)
The researchers found wide expression of GALNT1 in lower and upper respiratory tract cells that are susceptible to SARS-CoV-2 infection, indicating that the enzyme could influence infection in humans. (nih.gov)
The gene responsible for food-triggered Cushing syndrome has been identified by an international team that includes researchers from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. (nih.gov)
Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans. (bio-peptide.com)
But in a new study, researchers reveal how they are a step closer to developing a blood test that can identify whether a respiratory illness is caused by a viral or bacterial infection, allowing more accurate antibiotic prescribing. (medicalnewstoday.com)

Analytical approaches were developed to identify biosets in a genomic database in which AhR activity was altered. (nih.gov)
Compared with pathway analyses using only one type genomic data, we found integrative analysis can increase the power to identify the real associations and provided more stable and accurate results. (oncotarget.com)

Model inputs included clinical data and RNA-Seq based gene expression data. (nih.gov)
In this study, we have generated a specific kinome gene signature, named Kinome-27, which is able to identify a subset of HR-NBL tumors, named ultra-HR NBL, with highly aggressive clinical behavior that not adequately respond to standard treatments. (uni-koeln.de)
The use of our signature in clinical practice will allow identifying patients with negative outcome, which would benefit from new and more personalized treatments. (uni-koeln.de)
Investigating mechanisms of resistance to ibrutinib, we identified mutations in BTK and PLCG2 in most patients with CLL progressing on ibrutinib, showed that these mutations are often detectable long before the diagnosis of clinical relapse, and identified emergence of multiple subclones carrying different mutations. (nih.gov)
More than ever identifying each level of HER2 expression is critical for clinical decision making. (videomarketingplatform.co)

Facial expression images were correctly matched in 89% of emotive scenario presentations on average. (kcl.ac.uk)
The facial expression generated in response to an ambiguous threat scenario was correctly matched to ambiguously threatening scenarios in 90% of scenario presentations. (kcl.ac.uk)
See if you can correctly identify the emotional expression displayed in each of the samples below. (paulekman.com)

One of the largest GWAS, involving DNA taken from individuals of European descent and conducted by the DIAGRAM (DIAbetes Genetics Replication And Meta-analysis) consortium, identified 65 loci associated with type 2 diabetes risk ( 1 ). (diabetesjournals.org)
Therefore, the integrative analysis method combining multiple levels of evidence can more precisely and comprehensively identify the pathway associations. (oncotarget.com)
Finally, an unbiased proteomic analysis identified relevant changes in the neuronal protein landscape suggesting abnormal ER protein metabolism and calcium dysregulation. (jneurosci.org)
Then, B3GNT3 and PD-L1 expression were evaluated by immunohistochemical analysis in 145 surgically resected primary lung adenocarcinomas. (elsevierpure.com)
Significance Analysis for Microarrays software was used to identify genes that were differentially expressed between patients with partial response compared to those with disease progression. (elsevierpure.com)
A global analysis of approximately 54,000 probe sets identified 4 genes that had expression correlated with response. (elsevierpure.com)

Therefore, the evaluation of gene expression and associated mechanisms of beef cattle at arrival may lead to the development of rapid diagnostics which accurately predict BRD development and severity. (researchsquare.com)
2011 Therefore it is important to understand the mechanisms by which miRNA expression is usually regulated during T cell activation. (sciencepop.org)
Identifying such Avr genes is a crucial step to understand the mechanisms of wheat -rust interactions. (bvsalud.org)
I am pursuing three major goals: First, identify pathogenic mechanisms to assist the development of targeted therapy. (nih.gov)

Activation induces extensive changes in the gene expression program of naive CD4+ T cells promoting their differentiation into helper T cells that coordinate immune responses. (sciencepop.org)
Altering Ago2 expression in T cells revealed that Ago proteins are limiting factors that determine miRNA large quantity. (sciencepop.org)
Dlg7 expression was not detected in differentiated cells obtained from hematopoietic colonies, nor was expression detected in purified T-cells, B-cells, and monocytes. (nih.gov)
In the identifying cell types section we identified B Cells with marker genes and in the exploring substructure section we further segmented B Cells in t-SNE space by lassoing. (10xgenomics.com)
Now that you've segmented the B cells in this dataset, you can choose to run differential expression between these subtypes like we did in exploring substructure . (10xgenomics.com)
To see if this process might also occur in people, the team analyzed RNA expression in cells from healthy volunteers. (nih.gov)
Here, we propose that by measuring mutational status and gene expression in single cells simultaneously, cancer stem cells can be uniquely distinguished from both mature cancer cells (based on gene expression) and healthy stem cells (based on mutational status) (Fig. 1a ). (nature.com)
In addition, expression of the PPAP2B protein product LPP3 was present in foam cells in human atherosclerotic plaques and oxLDL exposure up-regulated LPP3 in macrophages resulting in increased degradation of pro-inflammatory mediators. (ox.ac.uk)
As input the ccRemover package expects a normalized, log-transformed and centered matrix of gene expression measurements for single cells obtained from single-cell RNA-Seq (scRNA-Seq) or another high-throughput sequencing experiment. (r-project.org)
2014) This data set contains normalized and log transformed gene expression measurements for 81 cells and 14,147 genes. (r-project.org)

In this study, we used in vitro and in vivo models to further evaluate chemicals identified through Tox21 in vitro screens as FXR agonists and antagonists. (nih.gov)

We sought to evaluate Diversity Outbred (DO) mice as a tool for exposure threshold assessment and to identify genetic factors that influence benzene-induced genotoxicity. (nih.gov)
Using nonobese mice predisposed to type 1 diabetes and healthy counterparts, the team was surprised to notice that most genes in any given tissue of the diabetes-prone mice at any given time showed about the same expression levels as their disease-free controls. (genengnews.com)
The investigators used microarrays to compare the expression of 35,000 genes in each of the NOD mice with that of the NOD.B10 animals. (genengnews.com)

While there have been some successes when using such an approach ( 5 , 6 ), the presence of multiple known and unknown confounding factors that can affect gene expression means few disease-associated loci are robustly associated. (diabetesjournals.org)
Results: A candidate gene approach looking at VHL and known target genes did not identify any genes whose expression correlated with patient response. (elsevierpure.com)
Our approach enables the identification of LSC-specific gene expression programs and the characterization of differentiation blocks induced by leukemic mutations. (nature.com)

The EBSeqHMM package provides functions to identify genes and isoforms that have non-constant expression profile over the time points/positions, and cluster them into expression paths. (rdrr.io)

Using microarray technology, we generated a gene expression profile of human gastric cancer-specific genes from human gastric cancer tissue samples. (nih.gov)
Here, gene expression was studied in the inducible human CD34+ acute myelogenous leukemia cell line KG1 using oligonucleotide arrays and suppression subtractive cloning. (nih.gov)
Recognizing emotional expressions is enabled by a fundamental sociocognitive mechanism of human nature. (bvsalud.org)
The ability to recognize emotional expressions enables individuals to interpret the feelings of others, comprising a fundamental cognitive mechanism of human social life (Cacioppo, Cacioppo, Dulawa, & Palmer, 2014). (bvsalud.org)
Although the engineers admit that simple mimicry of human expressions may have limited applications, they believe that it could nonetheless help advance the manner in which we interact with assistive technologies. (newatlas.com)

The 2 studies used a Bayesian sparse factor model to combine differences in the expression of many genes into factors that serve as independent variables in a binary regression model to distinguish infected from noninfected individuals. (medscape.com)

Co-expression and functional analyses revealed that distinctive metabolic processes distinguish dormancy stages, with genes expressed during endodormancy involved in chromatin remodeling and reproduction, while the genes induced at ecodormancy were mainly related to pollen development and cell wall biosynthesis. (frontiersin.org)
OxLDL-induced foam cell formation was associated with changes in a subset of open chromatin and active enhancer sites that strongly correlated with expression changes of nearby genes. (ox.ac.uk)

Over-expression of WNT7A in an ovarian cancer cell line led to increased migration and invasive capacity. (nih.gov)
2010 Among the many miRNAs that switch expression there are several that regulate T cell clonal growth or differentiation (Monticelli et al. (sciencepop.org)
To identify known immature and mature B Cell types in the dataset. (10xgenomics.com)
Let's build on the work we've done in the identifying cell types and exploring substructure sections. (10xgenomics.com)
I lead work in my group that identified the lymph node microenvironment as a key site of CLL cell activation through B-cell receptor and NF-ĸB signaling. (nih.gov)
Results: We found that EGFR activation induced PD-L1 expression, and EGFR tyrosine kinase inhibitor (TKI) could reduce PD-L1 protein in EGFR-TKI-sensitive HCC827 and PC9 cell lines. (elsevierpure.com)
We will compare samples from 2 different cell lines (A549 and HepG2) to identify alternative promoters. (bioconductor.org)
Measurements of expression in single-cell RNA-Sequencing often suffer from a large systematic bias. (r-project.org)
A major source of this bias is the cell-cycle which introduces within-cell-type heterogeneity that can obscure the differences in expression between cell-types. (r-project.org)
The package ccRemover provides a method for identifying and removing the effects of the cell-cycle from single-cell RNA-Seq data. (r-project.org)
ccRemover uses the set of genes which are not annotated to the cell-cycle to identify the main effects that are present in the data. (r-project.org)
It then uses the cell-cycle annotated genes to identify which of the effects are related to the cell-cycle before removing them. (r-project.org)
These genes can be identified using your own methods or using ccRemover's built-in cell-cycle gene identifier. (r-project.org)

The scientists theorized that individual differences in GALNT1 expression could affect virus spread. (nih.gov)
Characterizing gene expression differences between HSCs, pre-LSCs and LSCs would be a valuable step towards that goal. (nature.com)

Out of the annotated 29,043 genes , 2392 genes were selected as SP genes with detectable expression levels. (bvsalud.org)

These results suggest that the anxious facial expression in humans serves to increase information gathering and knowledge of the potentially threatening environment through expanding the individual's visual and auditory fields. (kcl.ac.uk)
When a connected camera subsequently imaged the face of a person interacting with the robot, a second neural network was utilized to identify that individual's present expression, and visually match it to one that the robot was capable of making. (newatlas.com)

In addition, expression of the apoptotic regulators bcl -2 and bax was analyzed. (aacrjournals.org)

Gene expression homogeneity of variance, receiver operator characteristic (ROC) curve, and decision tree analyses were performed between severity cohorts. (researchsquare.com)
Gene expression analyses between two Prunus species highlighted the conserved transcriptional control of physiological activities in endodormancy and ecodormancy and revealed genes that may be involved in the transition between the two stages. (frontiersin.org)

This study describes a novel screening strategy for identifying factors in mouse liver that perturb AhR in a gene expression compendium. (nih.gov)

By integrating these data sets into machine learning models and interaction networks, we identified the anatomical, adaptive, neural, hemodynamic, endocrine, and humoral processes predictive of HTN, and its treatment-resistant and controlled subphenotypes. (nih.gov)
In general, most tracing studies use two types of quantification: one used to identify and explain the anatomical part of the group, and one used to determine the frequency of cutting the anatomical part described above. (wikipedia.org)

We demonstrated to on-target effects of ibrutinib on BCR and NF-ĸB signaling in blood and lymph node in vivo, revealed the impact of ibrutinib on platelet aggregation, and identified improvements in both humoral and cellular immunity on treatment. (nih.gov)

Particularly, methylation of the hub gene, RNF13 , was inversely correlated with expression, indicating that DNA methylation regulates gene co- expression of this smoking-associated module. (nih.gov)

Expressed genes4

Variants5

Profiling5

Pathways7

Patterns9

Variant3

Tumor6

Genes involved1

Regulation7

MRNA expression2

Facial expressions5

Therapeutic4

Inhibitors1

Abstract1

Genome5

Transcriptome1

Exonic2

Proteomics1

Quantitative trai2

Conclusions3

Progenitor3

Single nucleotide p1

Signatures5

Specimens1

Tissues3

Redundant3

Distinct4

Molecular1

Researchers6

Genomic2

Clinical5

Correctly3

Analysis6

Mechanisms4

Cells10

Vitro and in vivo1

Mice3

Approach3

Isoforms1

Human5

Bayesian1

Chromatin2

Cell13

Differences2

Detectable1

Individual's2

Regulators1

Analyses2

Screening1

Anatomical2

Humoral1

Regulates1