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  • cDNA
  • Aim of study: Analysis of in vitro and in vivo growth properties, differential chromosomal aberrations and differential gene expression patterns of non-tumorigenic hybrid cells compared to tumorigenic segregants and tumorigenic parental HeLa cells by cDNA microarray analysis. (aacrjournals.org)
  • phospholipase
  • Bollag WB, Xie D, Zheng X, Zhong X (2007) A potential role for the phospholipase D2-aquaporin-3 signaling module in early keratinocyte differentiation: production of a phosphatidylglycerol signaling lipid. (springer.com)
  • In addition, our group was the first to propose that aquaporin 3 cooperates with the lipid metabolizing enzyme phospholipase D, and forms a new lipid signal that regulates early differentiation of keratinocytes 2 . (licor.com)
  • They are also investigating the elevation of very low-density lipoprotein (VLDL), and a corresponding stimulation in aldosterone production involving phospholipase D, in obesity 3 . (licor.com)
  • homeostasis
  • Moreover, HSEE increased the expression of genes involved in skin hydration and homeostasis. (hindawi.com)
  • These findings suggest that the intra-endolymphatic sac steroids could make regulatory effects on the inner ear AQP-3 expression via vestibular aqueduct and modulate the homeostasis of endolymphatic fluids, encouraging the possibility that the endolymphatic sac could be a therapeutic window for the inner ear disease. (nii.ac.jp)
  • Here, I will summarize our current knowledge of the involvement of aquaporin-formed pores and tight junctions in epidermal water homeostasis - as well as in other functions - and their putative roles in skin dryness. (springer.com)
  • Bladder Cancer
  • A multicenter round robin test of PD-L1 expression assessment in urothelial bladder cancer by immunohistochemistry and RT-qPCR with emphasis on prognosis prediction after radical cystectomy. (caritasstjosef.de)
  • High PDL1 mRNA expression predicts better survival of stage pT1 non-muscle-invasive bladder cancer (NMIBC) patients. (caritasstjosef.de)
  • In stage pT1 non-muscle-invasive bladder cancer (NMIBC), high KRT20 and low KRT5 mRNA expression identify the luminal subtype and predict recurrence and survival. (caritasstjosef.de)
  • membrane
  • Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). (abcam.com)
  • salivary
  • They are involved in (1) nephrogenic diabetes insipidus, (2) brain water balance and hearing and (3) salivary secretion ( Li and Verkman, 2001 ). (tcdb.org)
  • keratinocytes
  • To investigate the potential of GA to regulate the expression of MMPs and collagen, GA was topically applied onto human keratinocytes and the C57BL/6J mice dorsal skin. (biochemj.org)
  • quantitative
  • We examined effects of a single insertion of dexamethasone into the rat unilateral endolymphatic sac on mRNA expression of the inner ear AQP family, transmembrane water transporters and putative endolymphatic fluid modulators, by means of real-time quantitative PCR. (nii.ac.jp)