• In recent years, bioinformatics analysis and the microarray technology have been used to identify transcriptomic alterations and differentially expressed genes (DEGs), as well as their physiological functions, in many diseases. (hindawi.com)
  • In this study, a suppression subtractive hybridization cDNA library approach was used for the identification of pathogen and plant genes that were differentially expressed during infection of the susceptible cultivar BRS Pérola of Phaseolus vulgaris L. A total of 979 unigenes (430 contigs and 549 singletons) were obtained and classified according to their functional categories. (frontiersin.org)
  • We describe the first report of RNA sequencing of 5' capped (Pol II) RNAs isolated from acutely hepatitis C virus (HCV) infected Huh 7.5 cells that provides a general approach to identifying differentially expressed annotated and unannotated genes that participate in viral-host interactions. (mdpi.com)
  • Liu C, Pan Y, Li Q, Zhang Y. Bioinformatics analysis identified shared differentially expressed genes as potential biomarkers for Hashimoto's thyroiditis-related papillary thyroid cancer. (medsci.org)
  • Bioinformatics approaches can identify differentially expressed genes (DEGs) and analyze DEG functions in diseases. (medsci.org)
  • Summary of top hits from Gene Set Enrichment Analysis (GSEA) of ERβ ligand-responsive differentially expressed genes commonly regulated by E2 and LY treatments identified in RNAseq study. (figshare.com)
  • In silico identification and characterisation of putative differentially expressed genes involved in common bean (Phaseolus vulgaris L.) seed development. (wallonie.be)
  • The differentially expressed genes (DEGs) in AD were screened in GSE48350 dataset. (nature.com)
  • The differentially expressed oxidative stress genes (DEOSGs) were analyzed by intersection of DEGs and oxidative stress-related genes. (nature.com)
  • Differentially expressed genes were identified via microarray analysis. (cdc.gov)
  • You can easily see a differentially expressed gene. (lu.se)
  • To do this: create a selection with two groups, confirm your selection and press the "Calculate differentially expressed genes" button on the menu. (lu.se)
  • Where DNA was available from unaffected parents, we discovered de novo mutations, implicating genes, including CHD3, SETD1A and WDR5. (mpi.nl)
  • Mutations in the X-linked Plp gene lead to dysmyelinating phenotypes and oligodendrocyte cell death. (rupress.org)
  • It is unclear how mutations in the TPM2 and MYBPC1 genes lead to the joint abnormalities characteristic of distal arthrogryposis type 1. (medlineplus.gov)
  • [ 2 , 3 , 4 ] A full list of the described mutations is available at the TBX5 Gene Mutation Database , an online locus-specific database that contains germline and somatic mutations of the TBX5 gene. (medscape.com)
  • Mutations of this gene introduce a premature stop codon and result in truncated protein versions. (medscape.com)
  • To date, more than 70 different FALDH gene mutations have been found in patients with Sjögren-Larsson syndrome. (medscape.com)
  • This syndrome is a result of mutations in the gene that codes for fatty aldehyde dehydrogenase. (medscape.com)
  • Hereditary hemochromatosis (HH) attributable to mutations in the HFE gene is the most common autosomal recessive disorder among adults of northern European origin. (cdc.gov)
  • A similar study in rats revealed that approximately the same sample size was required for rat brain mRNA expression studies.The mRNA levels of several genes were studied in 55 schizophrenia and 55 control prefrontal brain autopsies, using a novel and more powerful statistical analysis. (avhandlingar.se)
  • The mRNA expression of diagnostic genes was determined by qRT-PCR analysis. (nature.com)
  • R software was used in this study to identify DEGs in HT and PTC using data in Gene Expression Omnibus (GEO). (medsci.org)
  • According to the PPI network, PTPN6 , HLA-A , C3AR1 , LCK and ITGB2 are hub genes among HT-DEGs, whereas FN1 , CDH2 , SERPINA1 , and CYR61 are PTC-DEG hub genes. (medsci.org)
  • We downloaded the GSE75010 and GSE10588 datasets from the GEO database and performed weighted gene coexpression network analysis (WGCNA) as well as Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses. (hindawi.com)
  • Analysis of gene ontology using the best matched Arabidopsis locus showed that the Thellungiella unigenes represented all biological processes and all cellular components, with the highest number of sequences attributed to the chloroplast and mitochondria. (mcmaster.ca)
  • Enrichment analysis was performed by Gene Ontology and Kyoto Encyclopedia of Genes and Genomes. (nature.com)
  • The team of José A. Mercado of Universidad de Málaga in Spain developed transgenic strawberry plants expressing the glucanase gene bgn13.1 from T. harzianum . (isaaa.org)
  • Transgenic N. benthamiana plants expressing the CP gene of WMV II or ZYMV showed protection against symptom development when inoculated with WMV II and six other potyviruses: bean yellow mosaic (BYMV), potato Y (PVY), pea mosaic (PeaMV), clover yellow vein (CYVV), pepper mottle (PeMV), and tobacco etch (TEV). (apsnet.org)
  • Transgenic plants expressing the WMV II CP gene generally showed better protection against these potyviruses than those expressing the ZYMV CP gene. (apsnet.org)
  • Given this and other reports, it appears that transgenic plants that express a potyvirus CP gene will show at least a noticeable level of protection against symptom development when challenged by other potyviruses. (apsnet.org)
  • Enhanced oxidative-stress defence in transgenic potato expressing tomato Cu/Zn superoxide dismutases. (scielo.org.za)
  • Transgenic potato lines expressing hairpin RNAi construct of molting-associated EcR gene exhibit enhanced resistance against Colorado potato beetle (Leptinotarsa decemlineata, Say). (potatobeetle.org)
  • Furthermore, CPB larvae fed on transgenic plants exhibited reduced EcR transcripts, indicating the functionality of dsRNA EcR in silencing EcR gene expression. (potatobeetle.org)
  • To identify the photoreceptive molecule that regulates photoperiodic responses, in the present study, we have cloned and characterized the cDNA encoding an opsin gene expressed in the ayu brain, a putative site of the photoreceptor for photoperiodism. (bioone.org)
  • Using the DTS method, we have successfully identified an 1812-bp additional GUS gene from the complicated Arabidopsis seedling cDNA library. (nih.gov)
  • We produced 6578 ESTs, which represented 3628 unique genes (unigenes), from cDNA libraries of cold-, drought-, and salinity-stressed plants from the Yukon ecotype of Thellungiella. (mcmaster.ca)
  • The partial cDNA of EcR gene of CPB was amplified using specific primers in sense and anti-sense orientations, and cloned in pRNAi-GG vector flanked by an intronic sequence (pdk). (potatobeetle.org)
  • KEGG and GO analyses further indicated the involvement of these genes in bioprocesses, such as gonadotropin secretion, immune cell infiltration, and the SMAD and MAPK pathways. (hindawi.com)
  • 80%) and biological pathways (such as adipocytokine, Notch, Hedgehog and NOD-like receptor signaling) were not identified by previous gene array studies. (mdpi.com)
  • This study highlights gene regulatory pathways in the developing brain that may contribute to acquisition of proficient speech. (mpi.nl)
  • Targeting one single gene can lead to the development of escape mutants or may be insufficient to silence redundant pathways. (ejbiotechnology.info)
  • Intriguingly, some of the top-ranked transcripts are noncoding splicing isoforms, which imply diverse gene regulation mechanisms. (nature.com)
  • gene loci structures and their regulation. (nature.com)
  • Overexpression of GSK3 in cells antagonizes insulin regulation of these genes. (portlandpress.com)
  • In the present study we demonstrate that regulation of these three genes by feeding is normal in mice that express insulin-insensitive GSK3. (portlandpress.com)
  • The rat HMGCS2 gene contains elements that control its multihormonal regulation and tissue specificity ( 11 - 14 ). (aacrjournals.org)
  • Regulation of gene expression in Plasmodium falciparum (Pf) remains poorly understood. (biomedcentral.com)
  • The transcriptome of the Pf asexual intraerythrocytic developmental cycle (IDC) has been analysed and transcriptional regulation has been shown to orchestrate a continuous cascade of gene expression, with genes being induced once per cycle, in a "just-in-time" manner, only when the gene product is required by the cell [ 3 ]. (biomedcentral.com)
  • The question then arises as to how such fine-tuned regulation of gene expression is achieved in this extreme parasite. (biomedcentral.com)
  • Our study identified 9 key genes associated with oxidative stress and immune reaction in AD pathogenesis. (nature.com)
  • Oxidative stress is involved in the modulation of gene expression patterns and metabolic activities, characterized by the disruption of redox homeostasis 7 . (nature.com)
  • It is essential to exhaustively interrogate complex mRNA isoforms of protein-coding genes with an unified data resource. (nature.com)
  • In order to investigate representative mRNA transcript isoforms to be utilized as transcriptome analysis references, we utilized GTEx data to establish a top-ranked transcript isoform expression data resource for human protein-coding genes. (nature.com)
  • Distinctive tissue specific expression profiles and modulations could be observed for individual top-ranked transcripts of protein-coding genes. (nature.com)
  • One major difficulty confronted is complex alternatively spliced transcript isoforms in human protein-coding genes. (nature.com)
  • Therefore, information regarding reference annotated mRNA transcripts of respective human protein-coding genes would be beneficial for biomedical researches and pathological sequence variation analyses. (nature.com)
  • These studies provided us more information on the spliced transcript isoforms of protein-coding genes as well as more understanding on their expression profiles and translated protein products in human tissues and diseases. (nature.com)
  • Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice. (jax.org)
  • Synergistic effects of co-administration of suicide gene expressing mesenchymal stem cells and prodrug-encapsulated liposome on aggressive lung melanoma metastases in mice. (stembook.org)
  • Because of the huge size of the common wheat ( Triticum aestivum L., 2n = 6x = 42, AABBDD) genome of 17,300 Mb, sequencing and mapping of the expressed portion is a logical first step for gene discovery . (bvsalud.org)
  • Genome sequencing is the largest genetic test and looks at all of a person's DNA, not just the genes. (cdc.gov)
  • Of these unique sequences, over 35% had significant similarities to known genes by BLASTX searches, which allowed the identification of 14,776 unique genes in the catfish. (auburn.edu)
  • The study seeks to identify putative regulatory motifs in the upstream regions of 13 functional groups of genes expressed in the intraerythrocytic developmental cycle of Pf . (biomedcentral.com)
  • A total of 100 and 212 differently expressed genes were identified in the GSE75010 and GSE10588 datasets, respectively, and after overlapping with WGCNA results, 17 genes were identified. (hindawi.com)
  • A chromosome bin map of 16,000 expressed sequence tag loci and distribution of genes among the three genomes of polyploid wheat. (bvsalud.org)
  • Southern and Northern blots and reverse-transcription PCR analyses indicate that the same rhodopsin gene is expressed in the retina and the brain but not in the pineal organ of ayu. (bioone.org)
  • In the vertebrate CNS, HB9/MNR2 transcription factors are specifically expressed in all somatic motoneurons and are necessary to distinguish motoneurons from interneurons, in part by repressing interneuron-specific gene expression. (jneurosci.org)
  • Together, vertebrate HB9/MNR2 transcription factors are expressed in all somatic motoneurons and excluded from interneurons. (jneurosci.org)
  • The transcriptional profile of 11 fungal genes related to pathogenicity and virulence were evaluated by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). (frontiersin.org)
  • While over half the genes are estimated to be regulated at the transcriptional level, few regulatory motifs and transcription regulators have been found. (biomedcentral.com)
  • TFBMs act as binding sites for transcription factors and coordinate the expression of the genes in whose promoter regions they appear. (biomedcentral.com)
  • They are about 6-8 nucleotides (nt) in length and occur upstream of the gene transcription start site (TSS). (biomedcentral.com)
  • Finally, we constructed the drug, transcription factors (TFs), and microRNA network of the diagnostic genes. (nature.com)
  • The responsible gene has been mapped to band 12q24.1, which encodes the human transcription factor TBX5. (medscape.com)
  • In compound heterozygotes expressing rumpshaker and jimpy alleles, oligodendrocytes expressing the former predominated and were more abundant than when the rumpshaker and null alleles were in competition. (rupress.org)
  • It is not wise to use the normalized expression dataset you mentioned (RPKM - normalized to gene length), find the raw count matrix and then run the mentioned tools. (biostars.org)
  • The parallel analysis of ESTs from the two closely related ictalurid catfishes should also provide powerful means for the evaluation of ancient and recent gene duplications, and for the development of high-density microarrays in catfish. (auburn.edu)
  • Here, we identify and characterize the single Drosophila ortholog of the HB9/MNR2 gene family. (jneurosci.org)
  • Drosophila genes expressed specifically in all motoneurons have not been described, although a growing number of genes are known to be expressed in subsets of motoneurons. (jneurosci.org)
  • Drosophila HB9 differs from its vertebrate orthologs in several ways: it is not expressed in all somatic motoneurons, it is expressed in a subset of interneurons, and it is required for the proper development of both interneurons and motoneurons. (jneurosci.org)
  • Background: Gene expression measurements during the development of the fly Drosophila melanogaster are routinely used to find functional modules of temporally co-expressed genes. (sciweavers.org)
  • Expressed Sequence Tag (EST) sequencing is one of the most efficient means for gene discovery and gene expression profiling. (auburn.edu)
  • Molecular cloning and analysis of novel cDNAs specifically expressed in adult mouse testes. (jax.org)
  • In this study, we used bioinformatics analysis to identify hub genes, establish a logistic model, and study immune cell infiltration to clarify the physiopathogenesis of PE. (hindawi.com)
  • Additionally, protein-protein interaction network analysis identified 10 hub genes, six ( FLT1 , FLNB , FSTL3 , INHA , TREM1 , and SLCO4A1 ) of which were used to establish a logistic model for PE. (hindawi.com)
  • RT-PCR analysis also confirmed that, except FSTL3 , these genes were upregulated in PE. (hindawi.com)
  • Conclusion: Spatial information contributes to a detailed, biological meaningful analysis of temporal gene expression data. (sciweavers.org)
  • Liu H, Chen L, Giffen KP, Stringham ST, Li Y, Judge PD, Beisel KW, He DZZ (2018) Cell-specific transcriptome analysis shows that adult pillar and deiters' cells express genes encoding machinery for specializations of cochlear hair cells. (atsbio.com)
  • I would suggest using EdgeR, Limma, DESeq2 for differential gene expression analysis. (biostars.org)
  • Based on analysis of phylogenetic trees and exon/intron structure of Dok family members, DOK4 and DOK5 define a subfamily within dok genes distinct from DOK1, DOK2 and DOK3. (ox.ac.uk)
  • The immune-related DEOSGs and hub genes were identified by weighted gene co-expression network analysis (WGCNA) and protein-protein interaction (PPI) analysis, respectively. (nature.com)
  • The diagnostic value of hub genes was assessed by receiver operating characteristic analysis and validated in GSE1297. (nature.com)
  • We obtained 66 immune-related DEOSGs by intersecting turquoise module with the DEOSGs and identified 15 hub genes through PPI analysis. (nature.com)
  • Analysis of the relative rates of synonymous (dS) and nonsynonymous (dN) substitutions revealed that the RNA helicase genes were subjected to strong negative (purifying) selection. (syr.edu)
  • Meta-analysis was conducted to determine expression of the RNA helicase genes during the critical period (90-110 days post-fertilization, dpf) of male gonad differentiation. (syr.edu)
  • Subsequent differentiation allows for rear- analysis of a set of mouse B lineage cell lines rep- rangements of the Ig light-chain (IgL) genes that replace the resenting defined stages of B cell development us- surrogate light-chain genes on the surface of the B cell [8]. (lu.se)
  • Sjögren-Larsson syndrome (SLS) is diagnosed by demonstrating the enzyme deficiency or by mutation analysis of the FALDH gene. (medscape.com)
  • Here we report mapping of 7104 expressed sequence tag (EST) unigenes by Southern hybridization into a chromosome bin map using a set of wheat aneuploids and deletion stocks. (bvsalud.org)
  • Blue cells = expressed in wild-type. (jax.org)
  • A friend is interested in isolating genes that are expressed solely in liver cells but only has access to skin cells. (pearson.com)
  • In CaCo-2 colonic epithelial cells, the expression of this gene increases with cell differentiation. (aacrjournals.org)
  • Accordingly, immunohistochemistry with specific antibodies shows that HMGCS2 is expressed mainly in differentiated cells of human colonic epithelium. (aacrjournals.org)
  • Using lentiviral constructs, stable gene silencing is established both in dividing and non-dividing cells. (ejbiotechnology.info)
  • A new Northwestern Medicine study, published June 5 in the journal Frontiers in Immunology, provides data about immune cells and biological changes (gene expression) in pregnant people at multiple timepoints before and during pregnancy. (northwestern.edu)
  • This invention relates to a method for selectively separating live cells which have expressed a specific gene. (justia.com)
  • In the case that the translation products of a gene are cell surface molecules, a method for selectively separating cells which have expressed the specific gene, while being viable, is to make fluorescence labeled antibodies bind to the surface molecules for labeling the cells fluorescently, to identify fluorescing cells by flow cytometry, and to separate the identified cells with a cell sorter (Fluorescence Activated Cell Sorter, FACS). (justia.com)
  • In the case that the translation products of a gene are not cell surface molecules but localize in the cells (in the cytoplasm or in organella), the method described above cannot be adopted. (justia.com)
  • In this case, it is theoretically possible to fluorescently label the gene-expressing cells by introduction of fluorescence-labeled antibodies that are specific to the molecules localized in the cells into the cells, through microinjection and to separate the objective gene-expressing cells with the cell sorter described above based on the difference in fluorescence intensity of the cells with irradiation of laser beam or the like. (justia.com)
  • In the case that the translation products of the gene are not cell surface molecules, but molecules that are liberated into the extracellular fluid and that do not remain in the cell or near the cell membrane, it is very difficult to selectively trap the molecules to separate the cells expressing the specific gene, from other molecules with the approaches described above. (justia.com)
  • We used compound heterozygote mice to study the long-term fate of oligodendrocytes expressing either the jimpy or rumpshaker allele against a background of cells expressing a Plp -null allele. (rupress.org)
  • Although mutant and null oligodendrocytes were generated in equal numbers, the proportion expressing the mutant allele subsequently declined, but whereas those expressing the rumpshaker allele formed a reduced but stable population, the number of jimpy cells fell progressively. (rupress.org)
  • DOK4 and DOK5: new Dok-related genes expressed in human T cells. (ox.ac.uk)
  • Here, we describe the two new human dok-related genes DOK4 and DOK5 and present data showing the expression of DOK4 and DOK5 genes in T cells. (ox.ac.uk)
  • Genes are expressed, or turned on, at different levels in different types of cells. (cdc.gov)
  • immature cell is then subjected to negative selection to delete grouped based on their previously defined pheno- self-reactive cells before it leaves the BM to enter peripheral typic features, and a gene expression pattern for lymphoid organs, where it becomes a mature B cell [9]. (lu.se)
  • With considerable accumulation of RNA-Seq transcriptome data, we have extended our understanding about protein-coding gene transcript compositions. (nature.com)
  • Placenta expressed transcript 1 is a protein that in humans is encoded by the PLET1 gene. (wikipedia.org)
  • Gene expression differences between patients and controls can be used to find susceptibility genes and drug targets for a disease. (avhandlingar.se)
  • Pmca2 may be the first gene with a known mutated protein product that confers increased susceptibility to NIHL. (cdc.gov)
  • Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (nih.gov)
  • The subtraction method is a quick and economical technique to scan differential gene expression. (nih.gov)
  • 27 gene modules were obtained through WGCNA and turquoise module was the most relevant module. (nature.com)
  • Approximately 80-90% of HH cases are due to homozygosity for the C282Y allele in the HFE gene. (cdc.gov)
  • The expression of antifungal genes from Trichoderma harzianum has been used to confer plant resistance to fungal diseases. (isaaa.org)
  • Gain of short arm of chromosome 5 (5p) is the most frequent karyotypic change in CC. Methods: To examine the role of 5p gain, we performed a combination of single nucleotide polymorphism (SNP) array, fluorescence in situ hybridization (FISH), and gene expression analyses on invasive cancer and in various stages of CC progression. (columbia.edu)
  • myod1 (myogenic differentiation 1) gene expression in Xenopus tropicalis, assayed by in situ hybridization, NF stage 23 embryo, dorsal view, anterior left. (xenbase.org)
  • This study identified 10 hub genes in PE and used 6 of them to establish a logistic model and also analyzed immune cell infiltration. (hindawi.com)
  • One of the candidates identified was Drosha (RNASEN), a gene that is required in the first step of microRNA (miRNA) processing in the nucleus. (columbia.edu)
  • Genomic polymerase chain reaction (PCR) demonstrated that the ayu rhodopsin gene is intron-less. (bioone.org)
  • We integrated chromosome 5 genomic copy number and gene expression data to identify key target over expressed genes as a consequence of 5p gain. (columbia.edu)
  • In the study reported here, the potato cultivar Aviva was transformed with a cytosolic Cu/Zn superoxide dismutase gene from Arabidopsis thaliana using Agrobacterium-mediated gene transformation. (scielo.org.za)
  • Identification of 5p gene targets in CC denotes an important step towards biomarker development and forms a framework for testing as molecular therapeutic targets. (columbia.edu)
  • Therefore inactivation of GSK3 is not a prerequisite for insulin repression of these genes, despite the previous finding that GSK3 activity is absolutely required for maintaining their expression. (portlandpress.com)
  • Based on these findings, we propose that ketogenesis is an undesirable metabolic characteristic of the proliferating cell, which is down-regulated through c-Myc-mediated repression of the key metabolic gene HMGCS2 . (aacrjournals.org)
  • Results: Using a semi-supervised approach, constrained clustering with mixture models, we can find clusters of genes exhibiting spatio-temporal similarities in expression, or syn-expression. (sciweavers.org)
  • GSK3 inhibition in liver reduces expression of the gluconeogenic genes PEPCK (phosphoenolpyruvate carboxykinase), G6Pase (glucose-6-phosphatase), as well as IGFBP1 (insulin-like growth factor binding protein-1). (portlandpress.com)
  • Interestingly, insulin injection of wild-type mice, which activates PKB (protein kinase B) and inhibits GSK3 to a greater degree than feeding (50% versus 25%), does not repress these genes. (portlandpress.com)
  • We suggest for the first time that although pharmacological inhibition of GSK3 reduces hepatic glucose production even in insulin-resistant states, feeding can repress the gluconeogenic genes without inhibiting GSK3. (portlandpress.com)
  • Not all genes are expressed at the same time: For example, when you eat, your insulin gene turns on for a time to process food. (northwestern.edu)
  • The ability to inhibit two or more genes simultaneously from one single expression vector further widens the application spectrum of RNAi, both in functional studies and therapeutic strategies. (ejbiotechnology.info)
  • The 'CACA motif' was absent in functional groups expressed during the ring to early trophozoite transition. (biomedcentral.com)
  • For functional groups expressed in each transition, the motifs tended to be similar. (biomedcentral.com)
  • HMGCS2 , the gene that regulates ketone body production, is expressed in liver and several extrahepatic tissues, such as the colon. (aacrjournals.org)
  • Temporal changes in rat liver gene expression after cadmium and chromium exposure. (cdc.gov)
  • In this study, a total of 54 DExD/H-box RNA helicase genes including 37 DDX (DEAD-box) and 17 DHX (DEAH-box) genes were characterized in channel catfish (Ictalurus punctatus), and annotated through phylogenetic and syntenic analyses. (syr.edu)
  • hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (nih.gov)
  • However, alternatively compounded patterns of human protein-coding gene transcripts would complicate gene expression data processing and interpretation. (nature.com)
  • Moreover, they show significant clustering within a single co-expression module of genes highly expressed during early human brain development. (mpi.nl)
  • al 2006 "Regional and cellular gene expression changes in human Huntington's disease brain" This workflow loads the two necessary files (gene expression data & phenotype data), and creates the expression set object to be used by the R package limma, to test for DE. (myexperiment.org)
  • The T-box gene family is a group of related genes that play a critical role in human embryonic development. (medscape.com)
  • other 127 genes not found in the expression libraries were obtained from the ovary normalized library. (nih.gov)
  • The scientists looked at gene expression - rather than genes themselves - to gain a global understanding of biological changes. (northwestern.edu)
  • Investigation of hub genes for the development of potential therapeutic targets and candidate biomarkers is warranted. (nature.com)
  • On the basis of recent vertebrate studies, the HB9/MNR2 gene family is a prime candidate for a general determinant of somatic motoneuron cell type. (jneurosci.org)
  • Thus, vertebrate HB9/MNR2 genes are expressed specifically in somatic motoneurons and are essential for distinguishing motoneuron/interneuron cell types. (jneurosci.org)
  • The temporal gene expression measurements are taken as primary data for which pairwise constraints are computed in an automated fashion from raw in situ images without the need for manual annotation. (sciweavers.org)
  • To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)