Exposure oxidative stress. Medical search. Frequent questions

Key mechanisms are noise-triggered vascular inflammation and oxidative stress with subsequent endothelial dysfunction. (vendys2.com)
Assessment of gene expression demonstrated variable up-regulation in cellular mechanisms related to metal transport and storage, inflammation, and oxidative stress based upon aerosol composition. (cdc.gov)
Recent experimental studies reported the occurrence of lung inflammation and oxidative stress following acute and subacute exposure to WPS. (who.int)
Here, we wanted to verify the extent of inflammation and oxidative stress in mice chronically-exposed to WPS and to evaluate, for the first time, its effect on alveolar injury and DNA damage and their association with impairment of lung function. (who.int)
CONCLUSION: We show the persistence of lung inflammation and oxidative stress in mice chronically-exposed to WPS and demonstrate, for the first time, the occurrence of DNA damage and enlargement of alveolar spaces and ducts associated with impairment of lung function. (who.int)

This study aimed to investigate if gestational and lactational exposure to human-relevant doses of PAR could alter behavioural and brain oxidative stress parameters in the rat`s offspring. (physiciansweekly.com)
Effects of 900-MHz electromagnetic field emitted from cellular phone on brain oxidative stress http://omega.twoday .net/stories/5730284/ Dan gers of cell phone wi-fi radiation http://omega.two day.net/stories/5732829/ Parents. (twoday.net)

These data suggest that use of resveratrol as postremission therapy for acute promyelocytic leukemia as well as adjunctive therapy in patients with exposure to arsenic may decrease arsenic nephrotoxicity. (springer.com)
In a meta-analysis, psychological stress was shown to promote acute proinflammatory responses with elevations in interleukin (IL)-6, IL-1 β , and tumor necrosis factor alpha (TNF- α ) levels [ 15 ]. (hindawi.com)
Chronic exposure to carbon tetrachloride - and sometimes acute exposure to very high concentrations - produces liver and kidney damage [EPA 2000]. (cdc.gov)
The immediate effect of acute CCl 4 exposure by all routes is CNS depression [Laine and Riihimaki 1986]. (cdc.gov)
Acute hepatic injury usually manifests after CNS effects have subsided, typically 1 to 4 days after acute exposure. (cdc.gov)
Acute exposure to CCl 4 causes a hepatocellular pattern of injury, with elevated AST and ALT and primarily centrilobular (zone 3) damage. (cdc.gov)
On the basis of the results was assessed the effect on the hematological profile, oxidative stress parameters, and antioxidants biomarkers in tissues, in another acute test. (nel.edu)
Oxidative damage was not detected in the experimental common carp, however there were significant differences from control in superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR) in tissue after acute exposure to 13.8 μg.l-1 Fury 10 EW. (nel.edu)

Arsenic exposure was assessed in urine as the sum of inorganic arsenic metabolite concentrations (U-As) measured by HPLC-HG-ICP-MS, and in whole blood as total arsenic (B-As) measured by ICP-MS. Efficiency of arsenic metabolism was evaluated by a polymorphism (rs3740393) in the main arsenic methylating gene AS3MT measured by TaqMan allelic discrimination, and by the relative fractions of urinary inorganic arsenic metabolites. (lu.se)
The association of arsenic exposure with telomere length and mtDNAcn was only present in Bolivian women with a less efficient metabolism. (lu.se)
These results demonstrate that resveratrol could significantly scavenge reactive oxygen species, inhibit As 2 O 3 -induced oxidative damage, and significantly attenuate the accumulation of arsenic in renal tissues by facilitating As 2 O 3 metabolism. (springer.com)
For this purpose, two different drugs were used: (1) Sodium thiosulfate (STS), a CN antidote commonly used in humans in case of CN poisoning and (2) 4-methylpyrazole (4MP) which blocks ACN metabolism through the oxidative pathway, preventing CN formation. (cdc.gov)
Aβ-mediated oxidative stress results in mitochondrial dysfunction, impairment of glucose metabolism, loss of proteostasis and synaptic plasticity, altered signal transduction, neuroinflammation, and progressive loss of neurons 9 . (nature.com)

As a consequence, oxidative stress arises from an imbalance between oxidant and antioxidant compounds in favor of excessive free radical generation. (hindawi.com)
The exposure to cigarette smoke can increase this imbalance. (bvsalud.org)
On the basis of their evidence review, Dr Thomas Münzel (Johannes Gutenberg University, Mainz, Germany) and colleagues say it's becoming clear that transportation noise is associated with oxidative stress, vascular dysfunction, autonomic imbalance and metabolic abnormalities-potentially contributing to the development of cardiovascular risk factors, such as arterial hypertension and diabetes, as well as progression of atherosclerosis and increased susceptibility to cardiovascular events. (medscape.com)

Arsenic exposure was hypothesized to be positively associated with all four toxicity biomarkers, particularly in individuals with a less. (lu.se)
The production of ROS is strongly influenced by stress factor responses in plants, these factors that increase ROS production include drought, salinity, chilling, defense of pathogens, nutrient deficiency, metal toxicity and UV-B radiation. (wikipedia.org)
The question as to what causes the destruction of the dopamine-producing cells has puzzled researchers for years but a consensus is now emerging that Parkinson's disease is caused by oxidative stress and metal toxicity. (diagnose-me.com)
Carbon Tetrachloride Toxicity: What Are the Toxicological Effects of Carbon Tetrachloride Exposure? (cdc.gov)

Here, we test for adaptation or tolerance mechanisms in mice in response to chronic noise exposure. (vendys2.com)
Oxidative stress and inflammation in the vascular wall are essential mechanisms of atherosclerosis and vascular dysfunctions associated with risk factors such as metabolic diseases, aging, hypertension, etc. (frontiersin.org)
This review article will summarize the most recent findings on the functional roles of arginases in vascular diseases and/or dysfunctions and the underlying mechanisms in relation to oxidative stress and inflammations. (frontiersin.org)
Mechanisms of pathogenesis of atherosclerosis are complex interplay between bloodstream cells and arterial wall components that leads to a chronic state of vascular oxidative stress and inflammation ( Hansson and Hermansson, 2011 ). (frontiersin.org)
In the past decades, unambiguous evidence has been provided that heightened oxidative stress and vascular wall inflammation are the key mechanisms for initiation and progression of atherosclerosis and vascular diseases associated with the risk factors ( Hansson and Hermansson, 2011 ). (frontiersin.org)
Therefore, elucidation of mechanisms underlying oxidative stress and inflammations in the vascular wall will have important impact in understanding atherosclerosis and vascular diseases associated with cardiovascular risk factors and will eventually lead to novel and effective therapeutic modalities. (frontiersin.org)
Mechanisms of oxidative stress in the potentiation of noise -induced hearing loss by acrylonitrile. (cdc.gov)
The attenuation of metal/peroxide oxidative chemistry, as well as lipid peroxidation, appears to be the major chemical mechanisms by which NO may limit oxidative injury to mammalian cells. (researchgate.net)
[7] [8] The possible mechanisms of action of antioxidants were first explored when it was recognized that a substance with anti-oxidative activity is likely to be one that is itself readily oxidized. (wikipedia.org)
MAINZ, GERMANY - An updated evidence review strengthens the concept that exposure to environmental noise from road traffic and aircraft may increase the risk for heart disease and gets at the potential underlying pathophysiologic mechanisms. (medscape.com)
This paper makes an important contribution to our understanding of the mechanisms of cardiovascular damage resulting from noise exposure. (medscape.com)

Two prominent welding fume particulate metal components are nanosized iron (Fe) and manganese (Mn) which might induce oxidative stress and inflammation resulting in pulmonary injury. (cdc.gov)
H2O2 can induce hMSCs to produce oxidative stress response. (researchsquare.com)
Future studies should also assess the effect of paracetamol exposure on lung function outcomes given that paracetamol is proposed to induce oxidative stress on the airway. (medscape.com)

These spermatozoa also experienced increased mitochondrial generation of reactive oxygen species after 1 week of exposure, with elevated DNA oxidation and fragmentation across all exposure periods. (nature.com)
Human alveolar lung A459 epithelial cells were exposed to freshly generated metal NP mixtures at a target concentration of 100?µg/m3 for 6?hr and then harvested for assessment of cytotoxicity, generation of reactive oxygen species (ROS), and alterations in the expression of genes and proteins involved in metal regulation, inflammatory responses, and oxidative stress. (cdc.gov)
Exposure to reactive oxygen species (ROS) combined with proteasomal inhibition increased aggregates formation. (unboundmedicine.com)
[9] Research into how vitamin E prevents the process of lipid peroxidation led to the identification of antioxidants as reducing agents that prevent oxidative reactions, often by scavenging reactive oxygen species before they can damage cells. (wikipedia.org)
In lung tissue, lipid peroxidation, reactive oxygen species, superoxide dismutase activity and reduced glutathione were all increased by WPS exposure. (who.int)

Results suggested that supplementation with seabuckthorn extract helps to reduce oxidative stress in liver and muscle of rats during C-H-R exposure and post-stress recovery. (nih.gov)
Melatonin inhibits cholesterol secretion from the gallbladder, helps convert cholesterol to bile, and as an antioxidant can reduce oxidative stress on the gallbladder. (diagnose-me.com)
Furthermore, gene overexpression is also frequently associated to antifungal resistance as well as an increase in the activity of proteins that reduce oxidative damage. (intechopen.com)

Radio frequency electromagnetic radiation (RF-EMR) from GSM (0.9/1.8GHz) mobile phones induces oxidative stress and reduces sperm motility in rats http://omega.twoday.n et/stories/5818592/ Some Facts about. (twoday.net)

The effect of the extract was studied on lipid peroxidation and antioxidant parameters in liver and gastrocnemius muscle of rats on attaining the rectal temperature (T(rec)) of 23 degrees C during C-H-R exposure and after recovery (T(rec)37 degrees C) from C-H-R-induced hypothermia. (nih.gov)
Effect of maternal exposure of fluoride on biometals and oxidative stress parameters in developing CNS of rat. (fluoridealert.org)
The hematological profile well oxidative stress parameters and antioxidant defensive systems provide important information about the internal environment of organisms. (nel.edu)
Oxidative stress parameters in early developmental stages of common carp (Cyprinus carpio L.) after subchronic exposure to terbuthylazine and metribuzin. (nel.edu)
Hostovsky M, Blahova J, Plhalova L, Stepanova S, Praskova E, Marsalek P, Svobodova Z. Oxidative stress parameters in early developmental stages of common carp (Cyprinus carpio L.) after subchronic exposure to terbuthylazine and metribuzin. (nel.edu)
At the end of the exposure period, several respiratory parameters were assessed. (who.int)

Preclinical research has demonstrated many pathological symptoms in MDD patients, including deficiencies of neurogenesis, inflammatory responses, oxidative stress, and abnormal cytokine secretion [ 8 ]. (hindawi.com)
Evidence has been provided that activation of the vascular endothelial cells in the presence of the risk factors promotes oxidative stress and vascular inflammatory responses, leading to acceleration of atherosclerotic vascular disease. (frontiersin.org)
Recent research provides emerging evidence supporting an essential role of increased activity of arginases including arginase-I and arginase-II in causing eNOS-uncoupling, which results in vascular oxidative stress and inflammatory responses, and ultimately leading to vascular diseases. (frontiersin.org)
Interleukin-8 has been determined to serve as a primary cytokine mediating inflammatory responses induced by welding fume exposures in alveolar epithelial cells. (cdc.gov)

This study was conducted to evaluate the effect of radiofrequency wave (RFW)-induced oxidative stress in the eye and the prophylactic effect of vitamin C on this organ by measuring the antioxidant enzymes activity including: glutathione peroxidase (GPx), superoxide dismutase (SOD) and catalase (CAT), and malondialdehyde (MDA). (nih.gov)
reduced glutathione (GSH), on recovery of T(rec)37 degrees C, increased superoxide dismutase (SOD) during exposure and recovery, normalized CAT activity in liver during C-H-R exposure and an increase on recovery of T(rec)37 degrees C. The decreasing pattern of liver and muscle GST levels both in single-dose and five-dose extract treated rats was similar to that in untreated rats. (nih.gov)
Increased superoxide formation in the brain was mirrored by a downregulation of neuronal nitric oxide synthase (Nos3) and transcription factor Foxo3 genes, whereas Vcam1 mRNA, a marker for inflammation was upregulated in all noise exposure groups. (vendys2.com)
Chen SC, Chen CC, Kuo CY, Huang CH, Lin CH, Lu ZY, Chen YY, Lee HS, Wong RH (2012) Elevated risk of hypertension induced by arsenic exposure in Taiwanese rural residents: possible effects of manganese superoxide dismutase (MnSOD) and 8-oxoguanine DNA glycosylase (OGG1) genes. (springer.com)
However, supplementation with 100 and 400 mg/kg of BBR significantly lowered the antioxidant activities, and glutathione peroxidase (gpx) and superoxide dismutase (sod) expression levels, as well as reduced malondialdehyde (MDA) content caused by Cu2+ exposure (P (bvsalud.org)
In cells , antioxidants such as glutathione , mycothiol or bacillithiol , and enzyme systems like superoxide dismutase , can prevent damage from oxidative stress . (wikipedia.org)

Thirty-two adult male Sprague-Dawley rats were randomly divided into four experimental groups and treated daily for 45 days as follows: Control, vitamin C (L-ascorbic acid 200 mg/kg of body weight/day by gavage), test (exposed to 900 MHz RFW) and the treated group (received vitamin C in addition to exposure to RFW). (nih.gov)
This study was carried out to examine the antioxidative potential, if any, of seabuckthorn leaf aqueous extract, administered orally in rats at a dose of 100 mg kg(-1) both in single and five doses, 30 min before cold (5 degrees C)-hypoxia (428 mm Hg)-restraint (C-H-R) exposure. (nih.gov)
Intrauterine and Postnatal Exposure to High Levels of Fluoride Is Associated with Motor Impairments, Oxidative Stress, and Morphological Damage in the Cerebellum of Offspring Rats. (fluoridealert.org)
Systematic impacts of fluoride exposure on the metabolomics of rats. (fluoridealert.org)
Changes to ovary cells have been associated with radiofrequency radiation exposure in laboratory rats. (ewg.org)
Prenatal exposure to radiofrequency radiation in laboratory rats was associated with follicle degeneration and structural changes of ovary cells that produce estrogen. (ewg.org)
Exposure to radiofrequency radiation from cell phones was associated with the death of the uterine lining in laboratory rats. (ewg.org)
This study investigated the effect of the trans-resveratrol supplementation on the cardiac oxidative stress in rats exposed to cigarette smoke. (bvsalud.org)
Male Wistar rats were randomized into four groups: Control Group (CG), Exposure to Smoke Group (ESG), Antioxidant Group (AG) and Exposure to Smoke plus Antioxidant Group (ESAG). (bvsalud.org)

Sperm cells are particularly susceptible to damage from free radicals that can be generated from radiofrequency radiation exposure, since they lack the protective antioxidants typical of other cells in the body. (ewg.org)
We used an environmental justice framework to assess the role of dietary antioxidants in modifying the adverse effects of exposure to PM2.5 on blood pressure (BP) and to consider implications for health inequities. (confex.com)
Recent studies have demonstrated that antioxidants present in natural products protect cells by reducing H 2 O 2 -induced oxidative stress in vitro and in vivo ( 5 - 7 ). (spandidos-publications.com)

The process of ATP production in the mitochondria, called oxidative phosphorylation, involves the transport of protons (hydrogen ions) across the inner mitochondrial membrane by means of the electron transport chain. (wikipedia.org)
Lycopene prevents Di-(2-ethylhexyl) phthalate-induced mitophagy and oxidative stress in mice heart via modulating mitochondrial homeostasis. (cabi.org)

Previous in vitro and in vivo studies revealed that oxidative stress caused by the accumulation of Aβ contributed to the initiation of AD 8 . (nature.com)

Co-exposure to carbon black and Fe2O3 particles causes a synergistic oxidative effect that is significantly greater than the additive effects of exposures to either particle type alone. (rti.org)
The intracellular redox reaction between carbon black and Fe3+ is likely responsible for the synergistic oxidative effect. (rti.org)
The results confirm that the fluoride provoked oxidative stress and biometal deformations are synergistic that successively governs the neuronal damage and developing CNS no longer prevents exacerbations of fluoride. (fluoridealert.org)

The mechanism by which ACN renders the cochlea more vulnerable to noise damage is still unknown, but we hypothesize that the decrease of GSH and/or the inhibition of SOD reduce the cochlear intrinsic anti-oxidant defenses and ultimately create oxidative stress. (cdc.gov)

Trans-resveratrol is a polyphenol with great antioxidant action that reduces the oxidative stress. (bvsalud.org)
4G is much more efficient than 2G in data transmission, which reduces exposure time," Rahban explained. (msdmanuals.com)

Protein oxidation, lipid peroxidation, and cellular uptake of Fe in these cells were measured after 25 hours of exposure. (rti.org)
No significant difference in cellular iron uptake was found between single exposure and co-exposure, when the Fe2O3 dosing concentration was the same in each case. (rti.org)
Activation of this receptor leads to increased oxidative stress that may result in cellular damage. (diagnose-me.com)
In addition to these chemical and biochemical properties, NO can modulate cellular and physiological processes to limit oxidative injury, limiting processes such as leukocyte adhesion. (researchgate.net)

Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis https://omeg a.twoday.net/stories/60120 53/ The effect of electromagnetic radiation in the mobile phone range on the behaviour. (twoday.net)
Pathophysiology of cell phone radiation: oxidative stress and carcinogenesis with focus on male reproductive system. (twoday.net)

In addition, co-exposure induced significant lipid peroxidation, although exposure to either particle type alone did not. (rti.org)

Oxidative stress and proteasomal dysfunction are implicated in the pathogenesis of PD but their interactions as well as their effect on aggregates formation are not yet clear. (unboundmedicine.com)

In this study, we examined the cytoprotective effects of cyanidin-3-glucoside (C3G) isolated from mulberry fruit against pancreatic β-cell apoptosis caused by hydrogen peroxide (H2O2)-induced oxidative stress. (spandidos-publications.com)
However, the excessive generation of ROS, such as super oxide anions (O 2 − ) and hydrogen peroxide (H 2 O 2 ) due to environmental stress results in significant oxidative damage to cell structures, such as DNA, the mitochondria and cell membranes ( 3 , 4 ). (spandidos-publications.com)

C57BL/6J mice were exposed to aircraft noise for 0, 4, 7, 14 and 28d at a mean sound pressure level of 72 dB(A) and peak levels of 85 dB(A). Chronic aircraft noise exposure up to 28d caused persistent endothelial dysfunction and elevation of blood pressure. (vendys2.com)
Endothelial dysfunction and inflammation were present during the entire 28d of aircraft noise exposure. (vendys2.com)
New, in particular, are studies demonstrating that even one night of aircraft noise exposure can cause vascular (endothelial) dysfunction in healthy subjects," said Münzel. (medscape.com)

To observe the effect of H2O2 induced oxidative stress on autophagy and apoptosis of human bone marrow mesenchymal stem cells (hBMSCs). (researchsquare.com)
This experiment intends to activate the oxidative stress response by H2O2, regulate the autophagy level of human bone mesenchymal stem cells (hBMSCs), and observe the effect of autophagy on the proliferation and apoptosis of hMSCs under oxidative stress. (researchsquare.com)

These data further illustrate health side effects of long-term noise exposure and further strengthen a consequent implementation of the WHO noise guidelines in order to prevent the development of noise-related future cardiovascular disease. (vendys2.com)
Air pollution exposure results in increased oxidative stress, linked to poor cardiovascular outcomes. (confex.com)
Excessive daily exposure of it may lead to an increased risk of cardiovascular disease (CVD). (cabi.org)

It can be concluded that RFW causes oxidative stress in the eyes and vitamin C improves the antioxidant enzymes activity and decreases MDA. (nih.gov)

Mobile phone devices receive and emit radiofrequency-electromagnetic energy (RF-EME) to transfer information, and accordingly our exposure to this form of energy is now unprecedented. (nature.com)
In both human and animal studies, exposure to radiofrequency radiation emitted from wireless devices is absorbed by the body and can harm the reproductive system. (ewg.org)
Exposure to radiofrequency radiation during pregnancy is associated with increased fetal and newborn heart rate and decreased fetal cardiac output. (ewg.org)
Prenatal exposure to radiofrequency radiation in laboratory mice was associated with lower levels of testosterone and behavioral anomalies. (ewg.org)
Exposure to radiofrequency radiation is associated in human studies with lower sperm concentration, viability, and motility. (ewg.org)
Evidence of the effects of radiofrequency radiation exposure on sperm quality has also been observed in animal studies. (ewg.org)
In animal studies, changes in the concentration of testosterone, luteinizing hormone and follicle-stimulating hormone in serum or in testicular samples have also been linked to exposure to radiofrequency radiation. (ewg.org)
ABSTRACT: Hazardous health effects stemming from exposure to radiofrequency electromagnetic. (twoday.net)

Results showed that in cultured human-derived retinal pigment epithelial ARPE-19 cells , the extract of Chlorella zofingiensis and its nutritional ingredient astaxanthin exhibited significant inhibitory effects on the formation of endogenous N ε -carboxymethyllysine (CML), a key AGE representative, through the suppression of intracellular oxidative stress. (rsc.org)

We used behavior, growth, photochemical efficiency, Symbiodiniaceae (symbiont) cell density, and total chlorophyll cell content to characterize thermal resilience and examined Symbiodiniaceae community composition responses at 1 and 13 days of exposure, and post-bleaching. (frontiersin.org)

The potential for this mechanism of biophysical interaction provides the impetus for well-designed studies to ascertain the effect of RF-EME following whole-body irradiation regimens that more accurately mimic human exposure. (nature.com)

Under oxidative stress conditions, hMSCs can promote protective autophagy and reduce cell apoptosis or the level of apoptosis caused by excessive autophagy. (researchsquare.com)
Autophagy is the process of maintaining cell homeostasis under oxidative stress conditions. (researchsquare.com)

[17] Exposure to ultraviolet (UV) radiation can cause direct photooxidation and decompose peroxides and carbonyl molecules. (wikipedia.org)
Novel and encouraging signs have recently been associated with olive oil aiding in wound healing and protecting against the damage incurred from ultraviolet radiation exposure. (researchgate.net)
In general, newer generations of mobile technology, like 4G and 5G, aim to reduce radiation exposure while offering improved data speeds and capabilities. (msdmanuals.com)

Cadenas S, Barja G (1999) Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO 3 . (springer.com)

Our study identified 9 key genes associated with oxidative stress and immune reaction in AD pathogenesis. (nature.com)
RÉSUMÉ Nous avons évalué la prévalence de la thyroïdite auto-immune dans un échantillon aléatoire de 1 188 élèves âgés de 8 à 13 ans recevant un apport d'iode standard en République islamique d'Iran. (who.int)

Taken together, our results demonstrated an antidepressant effect of THSG in a mouse model of MDD for the first time, and oxidative stress and inflammatory pathways were determined to play roles in this effect. (hindawi.com)
Role of oxidative stress-mediated cell death and signaling pathways in experimental fluorosis. (fluoridealert.org)
Pathways to Colorectal Cancer: Do excess energy consumption and the processes of oxidative stress interact and are they modulated by increased colonic permeability, inflammation, endotoxin exposure and toxic by-products of excess energy consumption? (who.int)

Additionally, continual oxidative stress from CCl 3 causes DNA damage, protein malfunction, and disrupted calcium homeostasis. (cdc.gov)
Oxidative stress is involved in the modulation of gene expression patterns and metabolic activities, characterized by the disruption of redox homeostasis 7 . (nature.com)

The CNS effects of chronic exposure are open to question. (cdc.gov)
In the case of chronic exposure, ongoing subclinical cell death promotes activation of stellate cells and collagen deposition. (cdc.gov)
Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L. (nel.edu)

Along with oxidative stress, WPS exposure significantly increased lung DNA damage index. (who.int)
Interestingly, we found dilated alveolar spaces and alveolar ducts with damaged interalveolar septae, and impairment of lung function following WPS exposure. (who.int)

In cases of lethal exposures, this histologic variation in injury is lost, and pronounced diffuse hepatic steatosis and frank liver necrosis can occur. (cdc.gov)
Aflatoxin exposure contributes to the development of primary liver cancer in patients with chronic hepatitis. (greenmedinfo.com)
ABSTRACT Currently no reports are available from Egypt regarding occupational exposure to nickel and its effects on the liver. (who.int)

In this study, the current exposure metric and two additional metrics, the surface area and the total number concentration, were evaluated by conducting simultaneous measurements of diesel ultrafine aerosols in a laboratory setting. (cdc.gov)

These findings call for additional efforts to evaluate and reduce arsenic exposure in Bolivia. (lu.se)
These findings suggest that CHOP is a fundamental factor that links protein misfolding in the ER to oxidative stress and apoptosis in β cells under conditions of increased insulin demand. (jci.org)

Oxidative stress and neuroinflammation play important roles in the pathogenesis of AD. (nature.com)

Aerosol exposures decreased cell viability and induced increased ROS production. (cdc.gov)
However, clinical practice and experiments have shown that ischemia, hypoxia, and inflammatory cell infiltration at the injured site will produce a large amount of ROS, forming an oxidative stress microenvironment. (researchsquare.com)
Taken together, our results suggest that C3G isolated from mulberry fruit has potential for use as a phytotherapeutic agent for the prevention of diabetes by preventing oxidative stress-induced β-cell apoptosis. (spandidos-publications.com)

However, the exposure of these cells to excessive levels of oxidative stress by too high levels of ROS or too low levels of antioxidative protection will render these cells dysfunctional thereby failing the fertilization process and causing couples to be infertile. (hindawi.com)

Specifically, interleukin-8 (IL-8) demonstrated the most robust changes in both transcriptional and protein levels after exposure. (cdc.gov)
We therefore examined the roles of oxidative stress and proteasomal inhibition on protein aggregates induction in naïve and neuronally differentiated neuroblastoma SH-SY5Y cells. (unboundmedicine.com)
Chronic ER stress promotes apoptosis, at least in part through the UPR-induced transcription factor C/EBP homologous protein (CHOP). (jci.org)

This review will address these aspects of the chemical biology of this multifaceted free radical and explore the beneficial effect of NO against oxidative stress. (researchgate.net)
We use Generalized Estimating Equations (GEE) to test simultaneously for the effect of ambient exposure PM2.5 and dietary antioxidant intake. (confex.com)
Results Dietary antioxidant intake was negatively associated with systolic BP (beta=-1.6, p-value=0.02) and pulse pressure (beta=-0.7, p-value=0.08), after accounting for the effect of ambient exposure of PM2.5. (confex.com)
We did not identify a significant modulating effect of dietary antioxidant on ambient exposure. (confex.com)
Although prenatal acetaminophen exposure (PAcE) can cause nervous and reproductive abnormalities in offspring, its effect on cartilage is uninvestigated. (cabi.org)

On 21st postnatal day, the concentration of fluoride, biometals, and oxidative stress markers were determined in discrete regions of CNS. (fluoridealert.org)
Arsenic and fluoride co-exposure through drinking water and their impacts on intelligence and oxidative stress among rural school-aged children of Lahore and Kasur districts, Pakistan. (fluoridealert.org)

The effects of subchronic exposure to terbuthylazine on zebrafish. (nel.edu)

Increased free radical activity ( oxidative stress ) appears to fuel Alzheimer's pathology - acting simultaneously as a mediator, product, and trigger for this "clogging" process and its related neural damage. (diagnose-me.com)

Exposure to air pollution, especially fine particulate matter, is a leading risk factor for noncommunicable diseases, in particular: ischaemia, myocardial infarction, stroke, chronic obstructive pulmonary disease and cancers. (who.int)

In plants, ROS are involved in metabolic processes related to photoprotection and tolerance to various types of stress. (wikipedia.org)
and how oxidative stress is associated with the biological processes underlying human ageing. (otago.ac.nz)

There is insufficient evidence of a link between early life exposure to acetaminophen (paracetamol) and asthma to warrant changing guidelines on early life paracetamol exposure, according to a systematic review and meta-analysis published online November 25 in the Arc hives of Diseases of Childhood . (medscape.com)
To better understand the possible risk, Cheelo and colleagues reviewed longitudinal studies of the association between paracetamol exposure in utero or during pregnancy and the development of childhood asthma at age 5 years or older. (medscape.com)

Effects of prenatal acetaminophen exposure at different stages, doses and courses on articular cartilage of offspring mice. (cabi.org)
The authors note several limitations of the study include only a small number of studies for each exposure period, limited statistical power, inability to quantitate publication bias, and marked heterogeneity among studies looking at prenatal exposure. (medscape.com)

I think there is no doubt anymore that chronic noise exposure, in particular nighttime noise, can cause coronary disease, heart failure, stroke, and arterial hypertension. (medscape.com)

OBJECTIVE AND HYPOTHESIS: To evaluate associations between arsenic exposure and telomere length, mtDNAcn, 8-oxo-dG, and 4-HNE-MA in Bolivians. (lu.se)

ROS formation gradually increases with ongoing exposure without significant adaptation or tolerance in mice in response to chronic noise stress at moderate levels. (vendys2.com)
The wood smoke exposure was associated with decreased serum levels of sICAM-1, and a tendency to decreased sVCAM-1 levels. (ku.dk)
UV or heat exposure), ROS levels can increase dramatically. (wikipedia.org)
In addition, we found that isolated islets from Chop -/- mice displayed increased expression of UPR and oxidative stress response genes and reduced levels of oxidative damage. (jci.org)
Nighttime noise has also been shown to decrease sleep quality and increase stress hormone levels. (medscape.com)

The supplementation of Trans-resveratrol attenuated the cardiac oxidative stress and increased the activity of catalase. (bvsalud.org)

Dietary berberine against intestinal oxidative stress, inflammation response, and microbiota disturbance caused by chronic copper exposure in freshwater grouper (Acrossocheilus fasciatus). (bvsalud.org)
Describe patterns of PM2.5 air pollution exposure, high blood pressure and dietary antioxidant intake in relation to racial, ethnic and socioeconomic characteristics of neighborhoods, in Detroit, MI. (confex.com)

Anatomy21

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