• EtOH has been linked to a number of neurotoxic effects on the fetus, which are dependent upon the extent and the magnitude of the maternal exposure to EtOH and for which very little is known with regard to the exact mechanism(s) involved. (gla.ac.uk)
  • The implemented experimental setting has provided a comparative view of the neurotoxic effects of maternal exposure to EtOH between gestation alone and a wider exposure timeframe that better covers the human third trimester-matching CNS neurodevelopment period (gestation and lactation), and has revealed a CNS region-specific susceptibility of the examined crucial neurochemical parameters to the EtOH exposure schemes attempted. (gla.ac.uk)
  • The extensive body of scientific research now available consistently indicates that Gulf War illness is real, that it is a result of neurotoxic exposures during Gulf War deployment, and that few veterans have recovered or substantially improved with time. (91outcomes.com)
  • Nerve agent protective pills administered to about 250,000 U.S. Gulf War troops (and other Coalition troops -- pyridostigmine bromide (PB) -- have also been implicated by medical researchers in Gulf War neurotoxic exposures. (91outcomes.com)
  • Mustard gas, prominent in the Iraqi chemical munitions arsenal at the time of the 1991 Gulf War including in the Khamisiyah detonations, has also been implicated in Gulf War Illness, including in a 2012 relook at Gulf War neurotoxic exposures funded by the chemical defense arm of the U.S. Department of Defense. (91outcomes.com)
  • Exposures to anesthetics in early life can also cause genomic and epigenomic changes, including reduced levels of proteins that regulate the development and function of neurons, such as BDNF and immediate early genes. (wikipedia.org)
  • Endocannabinoids are chemicals produced within the brain that modulate the overactivity of neurons such as GABA and are involved in circuitry regulation associated with many brain functions. (nih.gov)
  • The study, published last Wednesday in the online edition of the journal Environmental Heath Perspectives, is said to represent the first time researchers have found damage to neurons in rat brains exposed to radiation from mobile phones. (buergerwelle.de)
  • Now scientists have evidence that a group of neurons in a bow-shaped portion of the brain become hyperactive after chronic exposure to stress. (staycured.com)
  • The POMC neurons are in the arcuate nucleus, or ARC, of the hypothalamus, a bow-shaped brain region already thought to be important to how chronic stress affects behavior. (staycured.com)
  • The study also found that maternal exposure to plasticizers during pregnancy is associated with lower child IQ at age 14, which confirmed the results of two previous study on the topic. (neurosciencenews.com)
  • The current study has examined the effects of moderate maternal exposure to EtOH (10 % v/v in the drinking water) throughout gestation, or gestation and lactation, on crucial 21-day-old offspring Wistar rat brain parameters, such as the activities of acetylcholinesterase (AChE) and two adenosine triphosphatases (Na(+),K(+)-ATPase and Mg(2+)-ATPase), in major offspring CNS regions (frontal cortex, hippocampus, hypothalamus, cerebellum and pons). (gla.ac.uk)
  • We know that alcohol exposure is toxic to the developing fetus and can result in lifelong brain, cognitive, and behavioral problems," said Elizabeth Sowell, PhD, of the University of California, Los Angeles, who led the research team. (sciencedaily.com)
  • Detailed data about vulnerable brain structures may eventually be used to diagnose children with cognitive or behavioral problems but without well-documented histories of drug exposure. (sciencedaily.com)
  • Ultimately, the goal would be to come up with strategies to first, minimize brain damage in the womb, and second, to improve the child's cognitive performance," Beaulieu said. (sciencedaily.com)
  • A new study published in the Proceedings of the National Academy of Sciences explores how a pathway in the prefrontal cortex , a part of the brain associated with cognitive and emotional functioning, may play a role in this. (medicalnewstoday.com)
  • According to the study, "These findings offer a functional link between light exposure and [prefrontal cortex]-mediated cognitive and affective phenomena. (medicalnewstoday.com)
  • The research included tests designed to measure cognitive flexibility and working memory, which is the ability to hold and manipulate items in the brain for short periods of time. (scienceblog.com)
  • and Lovinger, D.M. Gestational alcohol exposure disrupts cognitive function and striatal circuits in adult offspring. (nih.gov)
  • BACKGROUND: Increasing evidence links higher particulate matter (PM) air pollution exposure to late-life cognitive impairment. (rti.org)
  • Excessive occupational exposure to Manganese (Mn) has been associated with clinical symptoms resembling idiopathic Parkinson's disease (IPD), impairing cognitive and motor functions. (cdc.gov)
  • While researchers have long known that drug abuse during pregnancy can alter fetal brain development, this finding shows the potential impact of meth. (sciencedaily.com)
  • The researchers were also able to predict a child's past exposure to drugs based on brain images and IQ information. (sciencedaily.com)
  • Christian Beaulieu, PhD, of the University of Alberta in Canada, who was unaffiliated with the study, said this finding will help researchers understand which brain areas are most sensitive to injury during development. (sciencedaily.com)
  • The researchers exposed their participants to varying levels of light to see if the light would activate certain regions of the brain. (medicalnewstoday.com)
  • Researchers from Brown University in Providence, RI, and from the Hebrew University of Jerusalem used functional MRI scans to determine how light intensity affects the brain. (medicalnewstoday.com)
  • The researchers viewed functional MRI scans to check which areas of the brain were activated during the light exposure. (medicalnewstoday.com)
  • The researchers found that moderate ultraviolet exposure in mice elevated levels of a molecule called urocanic acid in the brain, where it is not usually found. (nature.com)
  • Researchers found that in utero opioid exposure resulted in seven out of 14 2D biometric measurements of the fetal brain being smaller on magnetic resonance imaging (MRI) scans in comparison to fetuses without opioid exposure. (diagnosticimaging.com)
  • 1,2 With the data coming from single MRI scans obtained during the third trimester, the researchers said they could not assess the potential impact of opioid exposure on longitudinal brain development or during earlier time periods of pregnancy. (diagnosticimaging.com)
  • Drawing on the world-class UCLA Brain Mapping Center's experience in processing and analysing challenging brain data, such as these very young brains represented, the researchers could see the brain's anatomy and which areas of the brain were active during specific times. (uclahealth.org)
  • Structural MRI allows researchers to see the physical connections between brain cells, while functional MRI reveals which regions of the brain are active during a task. (uclahealth.org)
  • The researchers went on to measure electrical activity in the dorsal striatum-a brain region involved in learning and habit formation-as the offspring engaged in the decision-making tasks. (nih.gov)
  • Researchers said radiation from GSM mobile phones, which are prevalent around the world, was associated with leakage in the blood-brain barrier. (buergerwelle.de)
  • The situation of the growing brain might deserve special attention since biological and maturational processes are particularly vulnerable,' the researchers stated. (buergerwelle.de)
  • The memory and attention problems plaguing thousands of veterans from the first Gulf War might be caused by low-level exposure to insecticides and nerve gas, said researchers at Georgia Health Sciences University. (91outcomes.com)
  • In the latest review, the researchers reviewed 104 studies that analyzed exposure to pesticides and solvents that kill weeds, fungus, rodents and bugs, and the risk of Parkinson's disease. (time.com)
  • Then, six months after the end of the radiation dosing, researchers killed the mice and decapitated them, harvesting their tiny brains for study. (astronomy.com)
  • Researchers found both physical and chemical changes in the brains they examined, in addition to the behavioral changes they observed in the living mice. (astronomy.com)
  • Researchers establish connections between Alzheimer's-linked genetic alterations and the functioning of brain cells. (medindia.net)
  • These university researchers exposed mice to PBO during the period in their pregnancies that matches the early pregnancy period so critical in a baby's brain development. (birthdefectsvictims.com)
  • In-utero opioid exposure may lead to smaller fetal brain size and increased risk for breech presentations, according to a new prospective, multicenter, magnetic resonance imaging (MRI) study. (diagnosticimaging.com)
  • After performing 14 two-dimensional biometric fetal brain measurements, the study authors found that seven of the measurements were smaller in fetuses with opioid exposure in comparison to those without opioid exposure. (diagnosticimaging.com)
  • Nicotine may thus selectively disrupt central nervous system development by stimulating nicotinic receptors which are present in fetal brain, prematurely eliciting the events ordinarily triggered postnatally by cholinergic projections. (rti.org)
  • If it's replicated as a study it may indicate an insufficiency in our current standard,' said Robert Curtis, a scientist at the Occupational Safety and Health Agency and a member of a panel of the Institute of Electrical and Electronics Engineers that is crafting updated radiation exposure guidelines for mobile phones and communications transmitters. (buergerwelle.de)
  • long-term-radiation-exposure-from-space-travel-harms-memory-mood https://www.astronomy.com/space-exploration/long-term-radiation-exposure-from-space-travel-harms-memory-mood/ Long-term radiation exposure from space travel harms memory, mood The new research found irradiated mice were overly anxious, avoided light transitions, couldn't easily learn and remember, and showed behaviors linked to PTSD. (astronomy.com)
  • A general limitation of CT is radiation exposure. (medscape.com)
  • Cell phone tower studies which examined the relationship between radiation exposure and cancer rates were conducted in the city of San Francisco in addition to cities in Austria, Germany, and Israel, dating as far back as the 1970s. (naturalnews.com)
  • Prenatal alcohol exposure is a leading preventable cause of birth defects and neurodevelopmental abnormalities in the United States. (nih.gov)
  • In a new study conducted with mice, NIAAA scientists report that specific changes in a brain circuit involved in learning and decision making could underlie some of the behavioral effects of prenatal alcohol exposure. (nih.gov)
  • These findings suggest that treatments targeting the GABA and endocannabinoid systems might be useful in ameliorating impaired decision making associated with prenatal alcohol exposure. (nih.gov)
  • Future research could help translate this work to humans, clarifying how much these changes in behavior and circuits translate to people with a history of prenatal alcohol exposure. (nih.gov)
  • They also found that the blast wind, not the shock wave, leads to traumatic brain injury and long-term consequences. (sciencedaily.com)
  • The Report to Congress on Traumatic Brain Injury in the United States: Understanding the Public Health Problem among Current and Former Military Personnel [PDF - 130 pages] , developed by CDC, the National Institutes of Health, the Department of Defense, and the Department of Veterans Affairs, includes an overview of TBI among service members and Veterans. (cdc.gov)
  • Finally, the results showed an association between gestational exposure to plasticizers and smaller white matter volumes in girls. (neurosciencenews.com)
  • This study aimed to investigate if gestational and lactational exposure to human-relevant doses of PAR could alter behavioural and brain oxidative stress parameters in the rat`s offspring. (physiciansweekly.com)
  • The development of cholinergic systems in brain regions was evaluated biochemically in developing control rats and rats whose mothers received nicotine via continuous minipump infusion during gestational days 4 to 20. (rti.org)
  • To assess the developmental neurotoxicity of more realistic TRAP exposures, we exposed male and female rats during gestation and early postnatal development to TRAP drawn directly from a traffic tunnel in Northern California and delivered to animals in real-time. (nature.com)
  • WASHINGTON-A Swedish-funded study published in an U.S. government health journal says mobile-phone exposure caused brain damage in lab rats. (buergerwelle.de)
  • Perinatal exposure to the immune-suppressant di-n-octyltin dichloride affects brain development in rats. (openrepository.com)
  • Developmental immunotoxicity in male rats after juvenile exposure to di-n-octyltin dichloride (DOTC). (openrepository.com)
  • Immunologic effects of perinatal exposure of rats to dioctyltin dichloride. (openrepository.com)
  • In this context, a higher faecal excretion and lower tissue accumulation, as well as metallothionein induction in rats following exposure to methylmercury naturally incorporated in fish compared to methylmercury chloride added to the same matrix, have been reported [ 3 ]. (hindawi.com)
  • Laboratory experiments demonstrated that exposure to a single blast equivalent to a typical improvised explosive device results in CTE and long-term brain impairments that accompany the disease. (sciencedaily.com)
  • Surprisingly, the long-term impairments in brain function, including impaired learning and memory, were observed just two weeks after exposure to a single blast. (sciencedaily.com)
  • After two months of feeding with such diets, we analyzed the mercury accumulation in tissues, the mice body growth kinetics, the possible behavioral impairments, and the concentration of neurotransmitters in various brain structures. (hindawi.com)
  • However, experimental data linking tobacco smoke exposures to underlying mediators of neurodegeneration, including impairments in brain insulin and insulin-like growth factor (IGF) signaling in AD are lacking. (iospress.nl)
  • However, few studies have considered associations between direct estimates of long-term past exposures and brain MRI findings indicative of neurodegeneration or cerebrovascular disease. (rti.org)
  • A group of California teenagers exposed to common agricultural pesticides before birth had distinctive reductions in certain types of brain activity, according to a new study published in the Proceedings of the National Academy of Sciences . (scienceblog.com)
  • The study, which is the first to link differences in adolescents' brain activity to their level of prenatal pesticide exposure, adds to a large body of research about the health effects of organophosphate pesticides. (scienceblog.com)
  • Reiss and Baker hope their findings will provide a foundation for future research to understand how the pesticides change the activity of the human brain. (scienceblog.com)
  • In the end, we have to ask what's more expensive: to have a greater push toward organic farming or to have more individuals who need assistance because they are dealing with long-term effects of exposure to pesticides. (scienceblog.com)
  • Another study suggests that 80% of most people's exposure to pesticides occurs indoors and that measurable levels of up to a dozen pesticides have been found in the air inside homes [US Environmental Protection Agency 2012a]. (cdc.gov)
  • They chose to study pesticides and this particular birth defect because we already know that pesticides have been linked to other birth defects and they tend to have a greater effect on a developing brain than on an adult brain. (birthdefectsvictims.com)
  • Our team has over 30 years of combined experience in birth defects litigation in cases involving pesticides exposure. (birthdefectsvictims.com)
  • We propose that exposure to cholinergic insecticides disrupts the honeybee's ability to accurately encode wide-field visual motion, resulting in impaired optomotor behaviors. (frontiersin.org)
  • At the cellular level, the exposure of rodents and nonhuman primates to anesthesia during infancy causes developmental neurotoxicity, including widespread neuronal and glial apoptosis, and deficits in synapse and mitochondria structures and functions. (wikipedia.org)
  • At the end of the exposure (90 min), brain-isolated mitochondria were measured for mitochondrial respiration. (lu.se)
  • Children whose mothers abused methamphetamine (meth) during pregnancy show brain abnormalities that may be more severe than that of children exposed to alcohol prenatally, according to a new study. (sciencedaily.com)
  • In this study, we show that the effects of prenatal meth exposure, or the combination of meth and alcohol exposure, may actually be worse. (sciencedaily.com)
  • In this study, the authors found these brain regions in meth-exposed children were similar to the alcohol-exposed children, and in some areas were smaller still. (sciencedaily.com)
  • A new study utilized functional MRI scans to learn more about how the brain receives and processes light signals. (medicalnewstoday.com)
  • According to the study results, 26 brain regions showed what the authors referred to as "luxotonic-related activation," meaning these brain regions responded to light. (medicalnewstoday.com)
  • The study adds to a growing body of work in humans that light is used by the brain as a multi-purpose signal. (medicalnewstoday.com)
  • There have been several hypotheses about what effect an insult like organophosphate exposure would have on the brain," said experimental psychologist Joseph Baker , PhD, a co-author of the new study. (scienceblog.com)
  • The study found that during executive-function tasks, brain activation was decreased in the prefrontal cortex in teens with higher levels of prenatal pesticide exposure, as compared to teens whose exposure was lower. (scienceblog.com)
  • some study participants were estimated to have relatively low pesticide exposure levels while for others, exposure was much higher. (scienceblog.com)
  • It's really quite amazing that we see a long-term association between these exposures and brain function," said neuroscientist Allan Reiss , MD, a co-author of the study. (scienceblog.com)
  • In this study, investigators performed comprehensive neuropathological analyses on brain tissue from four military service personnel with known blast exposure and/or concussive injury. (sciencedaily.com)
  • Our results showed that the neuropathology from blast exposure, concussive injury, or both were virtually indistinguishable from those with a history of repeat concussive injury," said McKee, who is the director of the Brain Banks for BU's Alzheimer's Disease Center and the Center for the Study of Traumatic Encephalopathy, which are based at the Bedford VA Medical Center. (sciencedaily.com)
  • Studies on the effects of anesthesia exposures in early life on the mental and physical health of children have used both retrospective cohort study and prospective cohort study designs. (wikipedia.org)
  • Twenty-eight of the fetuses had opioid exposure, according to the study. (diagnosticimaging.com)
  • The study authors also found a 21 percent higher incidence of increased amniotic fluid volume (29 percent vs. 8 percent) and an 18 percent higher frequency of breech position (21 percent vs. 3 percent) with opioid-exposed fetuses in comparison to those without opioid exposure. (diagnosticimaging.com)
  • Noting that 71 percent of the opioid-exposed fetuses were also exposed to nicotine, the study authors conceded the possible effect of this exposure on the study findings as previous research has demonstrated a link between prenatal nicotine exposure and smaller brain size. (diagnosticimaging.com)
  • MRI findings in third-trimester opioid-exposed fetuses with focus on brain measurements: a prospective multicenter case-control study. (diagnosticimaging.com)
  • This study compared the activity patterns in the resting brain with the structural network and looked for differences between the alcohol-exposed infants and their unexposed counterparts. (uclahealth.org)
  • OBJECTIVE: Our objective was to quantify the association between brain MRI findings and PM exposures approximately 5 to 20 y prior to MRI in the Atherosclerosis Risk in Communities (ARIC) study. (rti.org)
  • A new study linked higher prenatal exposure to certain phthalates with reduced gray matter in children's brains by age 10. (neurosciencenews.com)
  • The new study estimates that 18% of the total effect of phthalate exposure in pregnancy on children's IQ could be explained by changes in gray matter volumes in both boys and girls. (neurosciencenews.com)
  • As limited data are available regarding piperacillin CNS exposure in patients without or with low-grade inflammation, a clinical study was conducted (1) to quantify CNS exposure of piperacillin by cerebral microdialysis and (2) to evaluate different dosing regimens in order to improve probability of target attainment (PTA) in brain. (uni-regensburg.de)
  • The study is essentially a proof of concept aimed at developing treatment targets: that a class of chemicals present in the 1991 Gulf War, organophosphates , could indeed have caused the brain damage found in research on MRI scans of representative samples of the 250,000 ill veterans of the 1991 Gulf War. (91outcomes.com)
  • I think the study is actually a big advance in our research knowledge of the relation between chemical exposures and the basic neurological injuries," Dr. Arch Carson of the University of Texas School of Public Health in Houston told MedPage Today . (time.com)
  • Exposure to flame retardants once widely used in consumer products has dropped over the 15 year period after the phase out of polybrominated diphenyl ethers (PBDEs), according to a new study by the Columbia Center for Children's Environmental Health at Columbia's Mailman School of Public Health. (medindia.net)
  • This study tests the hypothesis that cigarette smoke (CS) exposures can impair brain insulin/IGF signaling and alter expression of AD-associated proteins. (iospress.nl)
  • In conclusion, our study shows that effects from changes in Mn exposure are reflected in thalamic GABA levels and brain Mn levels, as measured by R1, in most brain regions. (cdc.gov)
  • Chronic unpredictable stress is widely used to study the impact of stress exposure in animal models, and in this case that included things like restraint, prolonged wet bedding in a tilted cage and social isolation. (staycured.com)
  • One study at the University of Wisconsin explored the effects of piperonyl butoxide , or PBO, on the brain development of mice. (birthdefectsvictims.com)
  • Identifying vulnerable brain structures may help predict particular learning and behavioral problems in meth-exposed children. (sciencedaily.com)
  • However, a systematic review and meta-analysis of prospective clinical studies found that while Full Scale Intelligence Quotient was not affected by a single anesthetic exposure, a single exposure to anesthesia before age three was associated with significant increases in parental reports of behavioral problems. (wikipedia.org)
  • Several retrospective studies have found that multiple exposures to anesthesia before the age of three are associated with an increased risk for worse academic achievement or behavioral disability in children who have undergone multiple exposures to anesthesia. (wikipedia.org)
  • Retrospective studies of early-life exposures to anesthesia have also reported an increased risk for behavioral problems or attention deficit hyperactivity disorder after multiple exposures to anesthesia before age three. (wikipedia.org)
  • This behavioral effect correlates with altered stress and detoxification gene expression in the brain. (frontiersin.org)
  • Using longitudinal survey data from US respondents linked to their Twitter feeds, we quantify the relationship between exposure to the Russian foreign influence campaign and attitudes and voting behavior in the 2016 US election. (nature.com)
  • The team saw brain-activity differences during executive-function tasks that correlated to the teens' levels of prenatal pesticide exposure. (scienceblog.com)
  • About half of women who say they used meth during pregnancy also used alcohol, so isolating the effects of meth on the developing brain is difficult. (sciencedaily.com)
  • Opioid exposure during pregnancy may cause a disruption in fetal neuromuscular development, potentially at the microstructural level, that results in breech presentation," suggested Nagaraj and colleagues. (diagnosticimaging.com)
  • The research, based on 775 mother-child pairs, determined that specific phthalate metabolites like mEP and mIBP during pregnancy lead to changes in children's brain structures. (neurosciencenews.com)
  • Children whose mothers had a higher exposure to certain phthalates during pregnancy tend to show smaller total gray matter in their brains at age 10 . (neurosciencenews.com)
  • Phthalate exposure of mothers was assessed using urine samples collected during pregnancy. (neurosciencenews.com)
  • The case with previous occupational exposure to mercury (case 28) was excluded from the regression analyses (see text). (biomedcentral.com)
  • Reversibility of neuroimaging markers influenced by lifetime occupational manganese exposure. (cdc.gov)
  • Prior studies have indicated possible increased occupational risks of cardiovascular disease as well as brain, lymphopoietic, bladder, kidney, and possibly lung cancers among firefighters. (cdc.gov)
  • Conclusions: These findings give insight into a mechanism involving genes, brain structure, and connectivity underlying why some adolescents find nicotine especially addictive. (kcl.ac.uk)
  • Effects of prenatal nicotine exposure on development of central and peripheral cholinergic neurotransmitter systems. (rti.org)
  • Prenatal exposure to nicotine had a marked adverse effect on developmental patterns of ChAT, uptake and uptake/ChAT only in cerebral cortex, the region previously shown to exhibit major abnormalities caused by this drug and other treatments with cholinomimetic effects. (rti.org)
  • A structure called the caudate nucleus, which is important for learning and memory, motor control, and motivation, was one of the regions more reduced by meth than alcohol exposure. (sciencedaily.com)
  • Sowell's team evaluated the specific effects of prenatal meth-exposure by comparing brain scans of 61 children: 21 with prenatal meth and alcohol exposure, 13 with heavy alcohol exposure only, and 27 unexposed. (sciencedaily.com)
  • This means that pregnant women who drink are less likely to try and minimize their reported drinking, and that coupled with the high rate of fetal alcohol exposure makes the region a hotspot for studying the effects of alcohol on the developing brain. (uclahealth.org)
  • The scientific community, public health authorities and others presumably will treat this as they would any researcher claiming a novel finding,' said Norm Sandler, director of global strategic issues for Motorola Inc. 'They will ask questions about the design, the exposures and the statistics underlying the reported results to assess its significance in a proper context. (buergerwelle.de)
  • MRI relaxometry was used to assess changes of Mn accumulation in the brain. (cdc.gov)
  • Evidence from nonhuman primate research suggests significant developmental neurotoxicity and long-term social impairment, with a dose-response relationship where repeated exposures cause a more severe impact than single ones. (wikipedia.org)
  • Epidemiologic studies have shown that exposure to PAR can increase the risk for developmental disorders, such as attention-deficit hyperactive disorder and autism spectrum disorder. (physiciansweekly.com)
  • One particularly devastating condition is holoprosencephaly, or HPE, a brain condition that can cause moderate to severe facial deformities, developmental delays, miscarriage, and early death. (birthdefectsvictims.com)
  • The prefrontal cortex is a region at the very front of the brain that is responsible for much of our conscious thought and decision making. (scienceblog.com)
  • Results: Exposure to smoking in adolescents, even at low doses, is linked to volume changes in the ventromedial prefrontal cortex and to altered neuronal connectivity in the corpus callosum. (kcl.ac.uk)
  • They found that offspring that had been prenatally exposed to alcohol had different decision-making strategies compared to those without prenatal exposure-prenatally exposed mice were more likely to rely on the cognitively demanding, goal-directed decision making at the expense of the less-demanding, habit-based decision making. (nih.gov)
  • Secondhand CS exposures caused molecular and biochemical abnormalities in brain that overlap with the findings in AD, and many of these effects were sustained or worsened despite short-term CS withdrawal. (iospress.nl)
  • These findings hit at the intersection of brain development and function, the socioeconomic status of our farm labor force, and the economics of crop production," Reiss said. (scienceblog.com)
  • McKee said that these findings indicate that TBI caused by different factors may trigger similar disease pathways in the brain. (sciencedaily.com)
  • Many preclinical neurological findings are limited in their translatability to humans due to differences in brain complexity and development between humans and rodents, as well as the difficulty in controlling and monitoring rodent physiology for safety during exposures. (wikipedia.org)
  • We estimated site-specific associations between PM and brain MRI findings and used random-effect, inverse variance-weighted meta-analysis to combine them. (rti.org)
  • Here, we show that sublethal exposure to two commonly used insecticides, imidacloprid (a neonicotinoid) and sulfoxaflor, results in impaired optomotor behavior in the honeybee. (frontiersin.org)
  • Brain maturation doesn't occur in isolation, but is all about adapting to the environment and developing based on the experiences that the individual has. (humaneexposures.com)
  • Traumatic brain injuries (TBI), including concussions, can occur in any type of workplace. (cdc.gov)
  • Typically, signs and symptoms of nitrogen mustard exposure do not occur immediately. (cdc.gov)
  • Depending on the severity of the exposure, symptoms may not occur for several hours. (cdc.gov)
  • Introduction: Cyanide exposure can occur in various settings such as industry and metallurgy. (lu.se)
  • We investigated the effects of acute (2-h) exposure to pulsed (2-micros pulse width, 500 pulses s(-1)) and continuous wave 2450-MHz radiofrequency electromagnetic radiation on DNA strand breaks in brain cells of rat. (nih.gov)
  • We speculate that these effects could result from a direct effect of radiofrequency electromagnetic energy on DNA molecules and/or impairment of DNA-damage repair mechanisms in brain cells. (nih.gov)
  • The brain is the primary target organ for exposure to radiofrequency electromagnetic fields (RF-EMF) during the use of the handheld wireless phone. (radiationrefuge.com)
  • This section discusses additional sources and pathways of exposure to hazardous substances in the home and environment that the health care provider should consider when taking an exposure history. (cdc.gov)
  • They compared these results with brain tissue samples from three young amateur American football players and a professional wrestler, all of whom had a history of repetitive concussive injury, and four samples from comparably-aged normal controls with no history of blast exposure, concussive injury or neurological disease. (sciencedaily.com)
  • Parkinson's is a neurological disease in which motor nerves in the brain lose their ability to function, leading to uncontrolled movements, tremors and difficulty in walking and speaking. (time.com)
  • Despite the current widespread availability, overall ease of performance, and safety profile of fetal MRI, studies of the brain on fetal MRI in opioid-exposed fetuses are scarce," wrote lead author Usha D. Nagaraj, MD, a pediatric neuroradiologist affiliated with the Cincinnati Children's Hospital Medical Center, and colleagues. (diagnosticimaging.com)
  • At the recent Models for Change National Working Conference , experts declared that adolescent brain development should play a greater role in determining how youths are treated in the juvenile justice system. (humaneexposures.com)
  • Adolescent brain development has played an increasingly important role in juvenile justice in recent years. (humaneexposures.com)
  • Panelist Richard Bonnie, director of the Institute of Law, Psychiatry and Public Policy at the University of Virginia, spoke of a 2012 National Research Council report he co-authored which concluded that the treatment of juvenile offenders should reflect knowledge about adolescent brain development. (humaneexposures.com)
  • Scientists have found new evidence of chronic traumatic encephalopathy (CTE) in brain tissue from blast-exposed military service personnel. (sciencedaily.com)
  • The investigators found that CTE neuropathology in the brains of blast-exposed military veterans was similar to that found in young athletes with repetitive concussion and consistent with what has previously been observed in brain samples from other athletes with a history of repetitive concussive injury. (sciencedaily.com)
  • Multiple exposures to anesthesia have been found to confer greater deficits in neurotoxicity, cognition and social behavior than single exposures. (wikipedia.org)
  • They found that exposure to bug and weed killers and solvents was linked to a 33% to 80% greater risk of developing Parkinson's disease. (time.com)
  • EPA's Total Exposure Assessment Methodology (TEAM) studies found levels of about a dozen common organic pollutants to be 2 to 5 times higher inside homes than outside, regardless of whether the homes were located in rural or highly industrial areas. (cdc.gov)
  • This review brings data about cancer types whose eatiology may be found in environmental exposure to xenoestrogens. (biomedcentral.com)
  • Highest risk was found in the area of the brain with highest exposure to RF-EMF. (radiationrefuge.com)
  • In addition, we also found decreased expression of Complex III and IV protein expression in brain tissue from the cyanide group. (lu.se)
  • Exposure to lead can have a wide range of effects on a child's development and behavior. (aacap.org)
  • Spitzer "thinks that our brains change their behavior (like 'a railway switching yard') based on environmental factors to help us conserve energy during winter," Quartz writer Rachel Feltman explains, noting that these environmental factors-and our reaction to them-are part of the reason people may suffer from seasonal affective disorder, a form of depression that hits during the winter months. (associationsnow.com)
  • Yet data have been unavailable to investigate links between exposure to foreign influence campaigns and political behavior. (nature.com)
  • Finally, we find no evidence of a meaningful relationship between exposure to the Russian foreign influence campaign and changes in attitudes, polarization, or voting behavior. (nature.com)
  • Exposure to selected TRAP components has been shown to cause various NDD-relevant outcomes in rodent models. (nature.com)
  • We investigated cerebral metabolism with a combination of brain respirometry, microdialysis, and western blotting using a rodent model of sub-lethal cyanide poisoning. (lu.se)
  • Thalamocortical functional connectivity in infants with prenatal opioid exposure correlates with severity of neonatal opioid withdrawal syndrome. (diagnosticimaging.com)
  • The international team established a method for imaging the brains of sleeping infants using MRI. (uclahealth.org)
  • Odor is inadequate to warn of toxic exposure. (cdc.gov)
  • TRAP exposure had no persistent effect on pro-inflammatory cytokine levels in the male or female brain, but did significantly elevate the anti-inflammatory cytokine IL-10 in females. (nature.com)
  • Brain exposure of piperacillin did not improve significantly with a prolongation of infusions. (uni-regensburg.de)
  • The main consequences of CS4 or CS8 exposures were to significantly reduce insulin R, IGF-1R, IRS-1, and tyrosine phosphorylated insulin R and IGF-1R proteins. (iospress.nl)
  • Despite small individual differences in brain volume and IQ, the widespread exposure to phthalates and lax regulations present a significant public health concern. (neurosciencenews.com)
  • This molecule is an intermediate in the conversion of histidine, an amino acid, to glutamate, a neurotransmitter that promotes electrical signalling in the brain. (nature.com)
  • GABA is the main inhibitory neurotransmitter in the brain. (nih.gov)
  • Inhalation is the primary route of exposure to elemental mercury vapor or aerosols, which are readily absorbed. (cdc.gov)
  • Adverse effects from exposure to mercury differ depending on the form and the route of exposure. (cdc.gov)
  • Adverse health effects caused by nitrogen mustards depend on the amount of nitrogen mustard to which people are exposed, the route of exposure, and the length of time that people are exposed. (cdc.gov)
  • Scientists have been looking for some time at the possible effects of exposure to the energy coming out of cellular phones,' said Jim Burkhart, science editor of Environmental Health Perspectives. (buergerwelle.de)
  • Much of the what is known about the long term health effects of exposure to mustard gas was learned following human experimentation at the end of WWII and documented in a government commissioned 1993 report by the Institute of Medicine, part of the National Academy of Sciences. (91outcomes.com)
  • Moreover, the research team observed that total gray matter volumes partially influence this relationship between exposure to certain phthalates and lower child IQ. (neurosciencenews.com)
  • Particularly in nonhuman primates, studies of exposures to anesthesia in infancy indicate that early-life anesthesia is associated with long-term changes in social behaviors, elevated anxiety and/or inhibition. (wikipedia.org)
  • CONCLUSIONS: Long-term past PM exposure in was not associated with markers of cerebrovascular disease. (rti.org)
  • Higher long-term past PM exposures were associated with smaller deep-gray volumes overall, and higher PM2.5exposures were associated with smaller brain volumes in the Minnesota site. (rti.org)
  • The sun exposure and general physical activity can improve your long-term brain function. (associationsnow.com)
  • It can certainly do so momentarily, but for long-term brain enhancement, exercise and vitamin D are more likely to help your case . (associationsnow.com)
  • For example, the Supreme Court has noted in key decisions that juveniles' brains are not fully developed, so youths are more susceptible than adults to peer pressure, more impulsive, more likely to take risks, less likely to consider long-term consequences and more amenable to rehabilitation. (humaneexposures.com)
  • Persons whose skin or clothing is contaminated with liquid mercury can contaminate response personnel by direct contact or off-gassing vapor and can also contaminate equipment leading to a risk of chronic exposure for response personnel. (cdc.gov)
  • A subset of ARIC participants underwent 3T brain MRI in 2011-2013 (n=1,753). (rti.org)
  • We estimated mean exposures to PM with an aerodynamic diameter less than 10 or 2.5μm (PM10and PM2.5) in 1990-1998, 1999-2007, and 1990-2007 at the residential addresses of eligible participants with MRI data. (rti.org)
  • The trials measured things such as whether the participants lived in close proximity to farms or other agricultural plots that use a higher volume of such chemicals, the likelihood of well-water consumption, rural living and various occupations that put an individual at a greater or lower risk of exposure. (time.com)
  • In self -guided VRET, participants can gradually increase their tolerance to exposure and reduce anxiety -induced arousal and PSA over time . (bvsalud.org)
  • Based on this approach, epidemiological studies set off many activities to reduce pollution and prevent exposure. (biomedcentral.com)
  • Competitive gymnasts have a higher exposure to potentially harmful flame-retardants than the general population, because such contaminants are present in foam used in gym equipments. (medindia.net)
  • Last September, a federal judge in Baltimore dismissed an $800-million brain cancer suit against Motorola. (buergerwelle.de)
  • Cancer types that have been well documented in literature to be related with environmental exposure include the reproductive system, breast, lung, kidney, pancreas, and brain. (biomedcentral.com)
  • The results of our data mining show (a) a significant correlation between exposure to xenoestrogens and increased, gender-related, cancer risk and (b) a need to re-evaluate agents so far defined as endocrine disruptors, as they are also key molecules in carcinogenesis. (biomedcentral.com)
  • Glioma is a malignant brain tumour ("brain cancer"), and the most common type is glioblastoma multiforme with a poor prognosis. (radiationrefuge.com)
  • NaturalNews) Could exposure to radiation from cell phone towers really responsible for over 7,000 cancer deaths? (naturalnews.com)
  • Prolonged or repeated exposures to nitrogen mustards have caused cancer in animals. (cdc.gov)
  • This research, which represents the first case series of postmortem brains from U.S. military personnel who were exposed to a blast and/or a concussive injury, will be published online May 16 by Science Translational Medicine . (sciencedaily.com)
  • According to neuroscientific research, exercise and sun exposure can increase brain activity. (associationsnow.com)
  • The research underscored that the connection between phthalate exposure and reduced IQ was partly due to alterations in gray matter volumes. (neurosciencenews.com)
  • Despite that, the results add to growing research about how exposure to environmental factors may play a role in diseases like Parkinson's. (time.com)
  • The research team will explore socioeconomic factors and social discrimination related to cannabis use in their investigation, planning to treat these variables as exposures of interest rather than controlling for their effects as previous studies have done. (ucalgary.ca)
  • There is not conclusive clinical evidence that a single, brief anesthetic exposure in children under the age of three is associated with a significant risk for neurodevelopment issues such as development of a learning disability, or deficits in academic performance or intelligence quotient. (wikipedia.org)
  • Exposure to ethanol during neurodevelopment modifies crucial offspring rat brain enzyme activities in a region-specific manner. (gla.ac.uk)
  • Conclusion Limited CNS exposure of piperacillin might be an obstacle in treating patients without general meningeal inflammation except for infections with highly susceptible pathogens. (uni-regensburg.de)
  • To examine the impact of a single blast exposure, the investigators collaborated with leading experts in blast physics, experimental pathology and neurophysiology at Boston University, VA Boston Healthcare System, White River Junction VA Medical Center, New York Medical College, Fraunhofer Center for Manufacturing Innovation, University of Massachusetts Lowell, Lawrence Livermore National Laboratory, Massachusetts General Hospital and the University of Oxford. (sciencedaily.com)
  • There is limited knowledge about how changes in exposure levels impact measures in magnetic resonance imaging (MRI). (cdc.gov)
  • Although R1 and GABA changed with Mn exposure, UPDRS was unaffected. (cdc.gov)