Explored the relationship between virulence. Medical search. Frequent questions

All of these offer ultimate explanations for virulence in pathogens. (wikipedia.org)
At one time, some biologists argued that pathogens would tend to evolve toward ever decreasing virulence because the death of the host (or even serious disability) is ultimately harmful to the pathogen living inside. (wikipedia.org)
The evolution of virulence in pathogens is a balance between the costs and benefits of virulence to the pathogen. (wikipedia.org)
However, the underlying mechanisms are not understood and a possible role for prophages in driving virulence of coral pathogens, as is the case for V. cholerae , has not yet been considered. (nature.com)
The course explores the molecular aspects of pathogenicity, virulence and antibiotic resistance of the major human pathogens, and their clonal relationship. (unict.it)
P/E -/- animals should be useful in testing the virulence of putative periodontal pathogens, in determining the role of host resistance factors in periodontitis, in exploring the proposed relationship(s) between infection mediated alveolar bone loss and systemic health disorders, and exploring their genetic relationships. (nyu.edu)
Hemolysins are crucial virulence factors which help pathogens to survive and persist in the host. (biomedcentral.com)
Flagellum was proven to have a significant function in adhesion of varied pathogens and is among the vital virulence elements10C12. (achemmic.com)

Presence of virulence genes in STEC and apathogenic E. coli strains The 52 STEC strains investigated in this study belonged to 20 different serotypes (Table 2). (micrornaassay.com)
In order to explore this relationship between EPEC and EHEC more closely, we investigated larger numbers of strains and serotypes of typical and atypical EPEC for thirteen virulence genes associated with EHEC O157 O-islands OI-122, OI-71, OI-57, the EHEC-plasmid and prophage CP-933N. (micrornaassay.com)
Additionally, the identified relationship between expressions of host immune genes and stx2 suggests that the host animal may regulate stx2 expression in colonizing STEC through immune functions. (frontiersin.org)
Variation in genes can be used to infer relationships between organisms. (binghamton.edu)
RESULTS: We found a striking increase in the overall abundance and expression of both virulence factors and antimicrobial resistance genes in COVID-19. (uni.lu)

Pathogen strains that kill the host can increase in virulence as long as the pathogen can transmit itself to a new host, whether before or after the host dies. (wikipedia.org)
The same mutations that enhance the reproduction and dispersal of the pathogen also enhance its virulence in the host, causing much harm (disease and death). (wikipedia.org)
The goal of the BioHealthBase is to facilitate the development of therapeutics, diagnostics and vaccines by integrating all available data in the context of host-pathogen interactions, thus allowing researchers to understand the root causes of virulence and pathogenicity. (mssm.edu)
It arises as a result of meteorological conditions, pathogen prevalence or virulence and host behaviour (Dowell, 2001). (projectguru.in)
Using domestic canaries we are exploring the role of parental incubation behavior in shaping host-pathogen interactions. (durantlab.com)
Ubiquitous sequencing will allow for the near real-time characterization of pathogen biology, including determinations of virulence, transmissibility, sensitivity or resistance to medicines or vaccines. (slideshare.net)

Genomic analysis, phenotype, and virulence of the historical Brazilian smallpox vaccine strain IOC: Implications for the origins and evolutionary relationships of vaccinia virus. (cdc.gov)
Develop a model to examine the variation in predictive disease transmission across counties in relationship to virus evolution (regional genomic characteristics), population immunity, public behavior, health policy decisions and population immunity, and to evaluate the mitigation effect of public health interventions. (cdc.gov)
Our experience of genomic sequencing of SARS-CoV-2 highlights the value of being able to build a very detailed picture of the virus and track its mutations for the potential to increase transmissibility, change virulence or influence the development of effective vaccines," said Mashe. (quadram.ac.uk)

Develop models that permit a comparative analysis of transmissibility and virulence between variants of concern during the course of the pandemic. (cdc.gov)

Virulence factors located on chromosomal pathogenicity islands also exist in some strains of V. coralliilyticus . (nature.com)

One definition of virulence is the host's parasite-induced loss of fitness. (wikipedia.org)
The magnitude of UTI depends upon both the bacteria's virulence and the host's susceptibility. (ispub.com)

She is doing her PhD thesis at Delft University of Technology in Thomas Abeel's group, exploring antimicrobial resistance in pathogenic bacteria. (broadinstitute.org)

He is currently exploring the impact of antibiotic use on the human gut resistome and the acquisition of antibiotic resistance elements during international travel. (broadinstitute.org)
Biofilm production has been shown to be an important UPEC virulence factor, as its formation creates an impermeable barrier for antibiotic penetration, and hence minimizing the amount of antibiotic that can reach the site of action, thus contributing to the development of resistance [ 7 ]. (clinmedjournals.org)
However, despite this staggering statistic, very few studies have investigated the relationship between biofilm production and host factors such age group and hospitalization status, and non-host factors, including recurrence of UTI, phylogenetic group distribution, and antibiotic susceptibility, among urinary E. coli isolates from reproductive age women. (clinmedjournals.org)
The pharmacodynamic study modelled the relationships between antibiotic exposure and AMR emergence over time for various classes of agents. (europa.eu)

The 21 apathogenic E. coli strains belonged to 18 different serotypes (Table 2) and were negative TPCA-1 for all virulence markers investigated in this study (Table 1). (micrornaassay.com)
This finding indicates that some EPEC strains are more related to EHEC in their virulence patterns, than others. (micrornaassay.com)
To explore the generality of this finding, we examined how an intermediate disturbance frequency affected pyoverdine production in 21 different strains of P. aeruginosa. (nova.edu)
In particular, the relationship between common electrolytes and the hemolysins of Candida strains has not been explored. (biomedcentral.com)

The presence of these genetic signatures indicates virulence in V. coralliilyticus is driven by prophages and other horizontally acquired elements. (nature.com)
Studies of population genetics have also created opportunities for strain identification and molecular taxonomy and for exploring the relationship between genetic diversity and properties of medical relevance such as virulence, resistance to drugs, antigenic variation, susceptibility to potential vaccines, and host and vector specificity. (bio.net)
SIVcpz does not cause an Aids-like illness among chimpanzees, despite its similarity to the human virus and the very close genetic relationship between chimps and humans. (balloon-juice.com)
The virulence of the bad part of self is always a product of a combination of factors including genetic constitution, parental and environmental influence both good and bad, and serendipitous events in infancy, childhood, and adolescence. (minnickskleinacademy.com)
Part of the public health measures taken by Zimbabwe included identifying the need to understand the detailed genetic epidemiology of SARS-CoV-2 and especially its behaviour in terms of transmission, capacity to mutate, and virulence. (quadram.ac.uk)

As well as solving the mystery of the origin of the virus, the findings prepare the way for future work exploring the history and behaviour of the simian form of HIV in its natural host. (balloon-juice.com)
The study also examined the relationship between comorbid substance use and behaviour frequency and explored common underlying risk factors for comorbid substance use. (who.int)
Ordinal logistic regression models were constructed to a) investigate the relationship between comorbidity and substance use behaviour frequency, and b) profile those with the greatest degree of comorbid substance use. (who.int)

Shiga toxin (Stx) is the main virulence factor of Shiga toxin-producing Escherichia coli (STEC), and ruminants are the main reservoir of STEC. (frontiersin.org)

To address these knowledge gaps, we are experimentally testing (1) how resources affect multiple mechanisms of host resistance and tolerance and (2) the functional consequences for ecological (host dynamics), epidemiological (disease invasion), and evolutionary (virulence evolution) dynamics. (durantlab.com)
Populations suffering today can take minimal consolation in knowing that HIV will follow that trajectory as earlier epidemics before it, and further we simply cannot know the time course that the de-virulence process will take if we leave it to evolutionary chance. (balloon-juice.com)

Moreover, there seems to be a relationship between phylogenetic background and virulence in UPEC, and how biofilm production potentially fits into this relationship has not been explored in urinary isolates from Australia. (clinmedjournals.org)

However, mixed metal exposure often exists in the actual working environment, and the interactive effects of polymetallic interactions on blood pressure and the dose-effect relationship remain unclear yet. (bvsalud.org)

Although the epidemiology of Candida species has been thoroughly studied, the virulence is not well understood. (biomedcentral.com)

Abby has worked on comparative genomics projects of many different bacteria, including analyses of whole genome sequences of M. tuberculosis , Enterococcus , Fusobacterium , E. coli , and other microbes, with particular emphasis on the evolution of drug resistance and virulence factors. (broadinstitute.org)

This process of inducing virulence in an otherwise harmless bacterium through prophage infection and integration of the prophage genome into the bacterial host genome is called lysogenic conversion 8 . (nature.com)
However, natural environments are subject to periodic fluctuations, including changes in physical forces, which could alter the spatial structure of bacterial populations and impact virulence factor production. (nova.edu)

Here we analyse five whole genome sequences of V. coralliilyticus to examine whether virulence is similarly driven by horizontally acquired elements. (nature.com)
The researchers say this heralds the application of these molecules as chemical probes to explore viral biology and produce specific antivirals targeting RNA regions of the coronavirus genome. (news-medical.net)

For about 100 years, the consensus was that virulence decreased and parasitic relationships evolved toward symbiosis. (wikipedia.org)
Before joining the Broad Institute, she received her PhD in biology from New York University where she studied the endosymbiotic relationship that parasitic nematodes have with the bacteria Wolbachia. (broadinstitute.org)

Uropathogenic E. coli (UPEC) are endowed with several virulence associated factors (VFs) that enable the organism to attach, invade, and injure the host. (clinmedjournals.org)
Understanding the environmental factors that affect the production of virulence factors has major implications in evolution and medicine. (nova.edu)
Our results suggest that environmental conditions shape robustness in the production of virulence factors and may lead to novel approaches to treat infections. (nova.edu)
Virulence factors, such as adherence, extracellular hydrolase production, hemolysis, phenotypic switching, and filamentation may all influence the pathogenesis of Candida species. (biomedcentral.com)
A variety of virulence factors are expressed by Candida albicans for the adaptation to specific anatomical sites [ 5 ]. (biomedcentral.com)
As one of the most important virulence factors of C. albicans , secreted aspartate proteinases (Saps) have been studied fully [ 6 ], while its hemolytic activity is not well understood. (biomedcentral.com)
p class=\'abstract\'>We assessed the relationship between the Patient Health Questionnaire-9 (PHQ-9) at intake and other measurements intended to assess biological factors, markers of disease and health status.We performed a cross-sectional analysis of 2365 participants from the Baseline Health Study, a prospective cohort of adults selected to represent major demographic groups in the USA. (stanford.edu)

Because H. pylori virulence factor CagA has been associated with aberrant expression of the transcription factor CDX1, which regulates intestinal differentiation, we explored its relationship with H. pylori infection and function during gastric carcinogenesis in normal gastric epithelial cells and gastric cancer cell lines. (figshare.com)
While spatial structure is important in virulence factor production, observations of this relationship have occurred in undisturbed or continuously disturbed environments. (nova.edu)
Hemolytic activity is a potential virulence factor that helps to disseminate candidiasis and facilitate hyphal invasion [ 7 ]. (biomedcentral.com)

The current craft of psychoanalysis consists in exploring the subjective implications related to the unveiling of desire and the uncertainties of identity arising from the unraveling of bans and norms established by patriarchal law. (bvsalud.org)
This paper aims to discuss the relationship between pharmacogenomics and dental practice, focusing on clinical implications and current researches. (bvsalud.org)

He came to the conclusion that virulence tends to remain especially high in waterborne and vector-borne infections, such as cholera and dengue. (wikipedia.org)
The development of a vaccine containing live cholera involves reducing the bacteria's virulence and ability to cause diarrhea while preserving its ability to induce an immune response. (nih.gov)

We don't limit our relationship to what's sexual to a role: libido is indeed not determined by gender identification. (bvsalud.org)

Linear regression and logistic regression were used to analyze the relationship between urinary lead, cadmium, and arsenic and blood pressure. (bvsalud.org)
Weighted quantile sum (WQS) regression was applied to evaluate the dose-effect relationship between urinary lead, cadmium, and arsenic exposures and blood pressure and the effect weight of each metal on blood pressure. (bvsalud.org)

For example, studies of the malaria parasite using rodent and chicken models found that there was trade-off between transmission success and virulence as defined by host mortality. (wikipedia.org)
Current studies mainly focus on the relationship between a single metal and blood pressure. (bvsalud.org)
A limited number of studies have explored the influence of specific ions on the hemolysins of Candida isolates. (biomedcentral.com)
In recent years, several studies have explored the potential role of pigment production in P. aeruginosa pathogenesis. (biomedcentral.com)
Seven such studies can be viewed on our open source wheat database, for those inclined to explore this connection further. (greenmedinfo.com)

Many research- agalactiae Isolate ers believe that GBS serotype does not correlate with evo- lutionary relationships. (cdc.gov)
The premise of the class was simple: learn about scientific research by exploring anything you find fascinating. (illinois.edu)
My research explored the impact of nitrogen pollution on biological oxygen demand and hypoxia within the Hudson River, which I conducted at Columbia's Lamont Doherty Earth Observatory. (illinois.edu)
Given the longstanding relationship and partnership between Zimbabwe and the UK in terms of academic and scientific research, the Quadram Institute was ideally placed to help provide support and expertise to NMRL in Zimbabwe where necessary. (quadram.ac.uk)
Pharmacogenomics is the application of genomics technology to the development of specific drugs and its relationship with dentistry is a recent area of research. (bvsalud.org)
Research on the relationship between oral health and systemic diseases gained rapid acceleration after the death of President Theodore Roosevelt in 1919 from odontogenic sepsis. (medscape.com)

Relationship between Body Mass Index and Bone Turnover Markers in Girls with Idiopathic Central Precocious Puberty. (medscape.com)

We evaluated the relationship between the pattern of liver enzymes and maternal mortality in eclamptic women. (bvsalud.org)

Foci of infection in the oral cavity and their relationship with the overall health of the human body have been long studied among healthcare practitioners throughout history. (medscape.com)

Conclusion This study shows that mixed exposure to lead, cadmium, and arsenic has a positive relationship with blood pressure, in which cadmium plays a major role. (bvsalud.org)

Whether GBS is a zoonotic organism has not been ade- niloticus) quately explored. (cdc.gov)

Aligned with the educational standards adopted by the Institute of Biomedical Science, our programme provides flexibility to explore various areas of biology based on your interests. (cumbria.ac.uk)

However, the host, being the parasite's resource and habitat in a way, suffers from this higher virulence. (wikipedia.org)
These three models help to explain the life history strategies of parasites, including reproduction, migration within the host, virulence, etc. (wikipedia.org)
Mark is an associate computational biologist interested in the relationship between host and microbiome. (broadinstitute.org)
Host-parasite relationships. (unict.it)
Flagellin, one of the most abundant proteins in the flagellum, is certainly stimulating web host disease fighting capability by relationship with Toll-Like-Receptor 5 (TLR5) and is known as to be a suitable vaccine adjuvant13. (achemmic.com)

Optimal virulence is a concept relating to the ecology of hosts and parasites. (wikipedia.org)

Small molecules that behave like drugs can be used to explore the function of various proteins and large molecules, acting as chemical probes. (news-medical.net)

Exploring the Relationship between Perfectionism and Pain in Patients with Temporomandibular Disorders: A Cross-Sectional Study. (medscape.com)
A narrative bibliographic review article was done with the search of original and review articles in international scientific mentales en adultos journals, in English and Spanish listing the relationship between the seroprevalence of T. gondii and the development of mental disorders in the adult population. (bvsalud.org)

Also, different types of statistical models available have been explored. (projectguru.in)

So far, there was no study designed to explore their epitopes using empirical methods. (achemmic.com)
We are currently using a newly established nest box system in Fayetteville, AR to study these relationships in Eastern Bluebirds. (durantlab.com)
LFLB1, DJOA2, VCFR3: study aumenta la posibilidad de desarrollar esquizofrenia y depresión en individuos sin historial previo, y que podría exacerbar conception, VCFR3: manuscript cuadros psiquiátricos previos con dificultad en el tratamiento. (bvsalud.org)

Objective To explore the influence proportion of occupational exposure to lead, cadmium, or arsenic on blood pressure and their interactive effects. (bvsalud.org)

The Relationship between the Serum NLRP1 Level and Coronary Lesions in Patients with Coronary Artery Disease. (medscape.com)

Paul W. Ewald has explored the relationship between virulence and mode of transmission. (wikipedia.org)
Ewald is convinced that the crowding of field hospitals and trench warfare provided an easy route to transmission that evolved the virulence of the 1918 influenza pandemic. (wikipedia.org)

Observing the trends of these events over a long period enables identifying hidden relationships. (projectguru.in)

Any movement on the virulence axis, towards higher or lower virulence, will result in lower fitness for the parasite, and thus will be selected against. (wikipedia.org)
In summary, dentistry begins to show an increasingly close relationship with pharmacogenomics, which may result in the development and improvement of treatment modalities more individualized and potentially more effective. (bvsalud.org)

Anatomy10

Organisms53

Diseases22

Chemicals and Drugs33

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Phenomena and Processes43

Technology, Industry, Agriculture2

Information Science4

Pathogens8

Genes5

Pathogen6

Genomic3

Transmissibility1

Pathogenicity1

Host's2

Antimicrobial1

Antibiotic4

Strains4

Genetic5

Behaviour3

STEC1

Evolutionary2

Phylogenetic1

Interactions1

Epidemiology1

Resistance1

Bacterial2

Genome2

Parasitic2

Factors7

Factor3

Implications2

Cholera2

Identification1

Urinary2

Studies5

Research6

Markers1

Mortality1

Infection1

Role1

Organism1

Biology1

Host5

Hosts1

Proteins1

Disorders2

Statistical1

Study3

Influence1

Disease1

Transmission2

Long1

Result2