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  • reducing membrane fluidity
  • Since the inner subdomains interconnect to form a ring, which can potentially segregate the lipids of the central hole from those outside, the 2D crystalline uroplakin network may impose an organized state and a severely restricted freedom of movement on the lipid components, thus reducing membrane fluidity and contributing to the barrier function of urothelial plaques. (biologists.org)
  • sphingomyelin
  • Sphingomyelin (d18:0/24:1(15Z)) or SM(d18:0/24:1(15Z)) is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath which surrounds some nerve cell axons. (hmdb.ca)
  • cholesterol
  • Recent experimental evidence supports rapid flip-flop of cholesterol in PC membranes, red cell membranes and, presumably, in most other cellular membranes (reviewed in Hamilton, 2003 ). (biologists.org)
  • One motif determines species-specific p10 fusion efficiency by governing formation of a cystine loop fusion peptide, while the other directs reversible clustering and multimerization of p10 in cholesterol-dependent membrane microdomains. (prolekare.cz)
  • This is the first example of a viral fusogen utilizing a membrane-proximal ectodomain region (MPER) to direct cholesterol-dependent multimerization and assembly into fusion platforms. (prolekare.cz)
  • Considerable controversy arose over the concept that cholesterol/sphingolipid-rich rafts in the T cell plasma membrane serve as a platform for TCR signalling reactions. (biomedcentral.com)
  • Similar effects are induced by methyl-β-cyclodextrin, which removes membrane cholesterol. (bmj.com)
  • motifs
  • Mutagenesis of CRAC motifs in SLC2A1 gene and limited proteolysis of membrane GLUT1 were used to determine the molecular effects of statins. (bmj.com)
  • accumulation
  • Accumulation of organelle content is signaled to the surface of yeast vacuoles in order to increase their storage capacity by homotypic membrane fusion. (biologists.org)
  • In the present study, we demonstrate that nerve injury induced accumulation of AMPAR GluA1 in postsynaptic membranes of the ACC pyramidal neurons in adult mice. (biomedcentral.com)
  • aggregation
  • The results demonstrate that formation of the photoprotective state requires a structural reorganization of the photosynthetic membrane involving dissociation of LHCII from PSII and its aggregation. (plantcell.org)
  • system
  • Photosystem II (PSII), in the thylakoid membrane of higher plants, possesses an extensive system of membrane-associated light-harvesting antenna complexes that increase its spectral and spatial cross section of absorbed solar energy, ensuring its efficient operation, even in low light (reviewed in Dekker and Boekema, 2005 ). (plantcell.org)
  • type
  • LRP-1 is shed at the cell surface by proteinases such as membrane-type 1 MMP (MT1-MMP) and a disintegrin and metalloproteinase-12 (ADAM-12). (frontiersin.org)
  • evidence
  • EEguchi and THWaterman, 1976, Freeze-etch and histochemical evidence for cycling in crayfish photoreceptor membranes, Cell Tiss. (slu.edu)