• Streptococcus pneumoniae and Neisseria meningitidis have is specific to the mechanism of resistance to penicillin G com- very similar mechanisms of resistance to penicillin G, which mon to S. pneumoniae and N. meningitidis and mediated by the are mediated by the decreased affinity of penicillin-binding decrease in affinity of their PBPs. (cdc.gov)
  • These are characterized as a receptor population with high affinity binding (Kd ∼ 17 μM) but relatively low abundance and a separate population with high abundance but much lower affinity (Kd ∼ 364 μM). (lancs.ac.uk)
  • The low-affinity binding sites are shown to be associated with the yeast cell aggregation. (lancs.ac.uk)
  • BSA01 exhibits strong affinity and internalization activity in vitro , while also demonstrating a good safety profile. (bmj.com)
  • the drug exhibits reduced affinity for the target site and becomes ineffective. (cdc.gov)
  • DNA affinity precipitation and mass spectroscopy of rs147978008 revealed allele-dependent binding of H1 histones, which was confirmed by using Western blotting. (cdc.gov)
  • Both 25D and DBP are synthesized and secreted by the liver, and because of the high binding affinity of DBP for 25D, most circulating 25D is tightly bound to DBP. (medscape.com)
  • Using a yeast two-hybrid screen for BAL-binding partners, we have now identified a novel protein termed BBAP (B-lymphoma- and BAL-associated protein). (nih.gov)
  • The MUC-1 arm of BSA01 binds to the cleaved MUC1-C*protein, which remains membrane bound on tumor cells. (bmj.com)
  • T1rs are class C G-protein coupled receptors (GPCRs), and the extracellular ligand binding domains (LBDs) of T1r1/T1r3 and T1r2/T1r3 heterodimers are responsible for binding of chemical substances eliciting umami or sweet taste. (nature.com)
  • The receptor activation mechanism of the class A GPCR members, consisting solely of the transmembrane region, has been considered to occur via agonist binding, which changes the conformational dynamics of the protein by lowering the transition energy between the different states, and results in the transition towards the active-state conformation 9 . (nature.com)
  • The radiolabelled protein showed strong binding to purified phosphatidylcholine and phosphatidylserine and weak binding to purified sphingomyelin, lysophosphatidylcholine and phosphatidylethanolamine, but did not interact with phosphatidic acid, lysophosphatidic acid or phosphatidylinositol. (tmu.edu.tw)
  • The POF protein sequence contains a putative RNA-binding domain. (the-scientist.com)
  • Electrophoretic mobility shift assays detected allele-dependent nuclear protein binding in A549 cells for 8 of 21 variants. (cdc.gov)
  • zooepidemicus strains in association with differences in M-like protein-mediated binding of host plasma proteins. (lu.se)
  • zooepidemicus strains that the M-like protein SzM is crucial for the binding of fibrinogen to the bacterial surface and for survival in equine and human blood. (lu.se)
  • Plasma protein absorption assays and flow cytometry analysis revealed that pronounced binding of human fibrinogen is a common phenotype of human S. equi subsp. (lu.se)
  • IgA autoantibodies in these patients have been shown to bind to desmogleins 1 and 3 in addition to an unspecified nondesmosomal transmembrane protein. (medscape.com)
  • We found that the GD of the receptor-binding domain of the SARS-CoV-2 spike protein is highly predictive of vaccine protection and accounted for 86.3% (P? (cdc.gov)
  • Of these, rs36115365-C associated with increased pancreatic and testicular but decreased lung cancer and melanoma risk, and exhibited preferred protein-binding and enhanced regulatory activity. (lu.se)
  • Proteomic analysis identifies allele-preferred binding of Zinc finger protein 148 (ZNF148) to rs36115365- C, further supported by binding of purified recombinant ZNF148. (lu.se)
  • Context Changes in vitamin D binding protein (DBP) concentrations and catabolism of 25-hydroxyvitamin D to 24,25-dihydroxyvitamin D (24,25D) after vitamin D2 supplementation may alter concentrations and bioavailability of circulating 25-hydroxyvitamin D (25D). (medscape.com)
  • The table below lists American painters who received special recognition, and/or whose exhibited works can be found in the Smithsonian Institution Research Information System database:[13] Except where noted, the paintings were exhibited in the United States section of the Palace of Fine Arts and listed in the initial catalogue. (wikipedia.org)
  • Results Binding competition assays indicate that the parental MUC1 antibody of BSA01 binds to MUC1-C*, which remains membrane-bound after cleavage. (bmj.com)
  • Risk and nonrisk oligonucleotides were tested for binding of nuclear extracts from A549, BEAS-2B, and IMR-90 lung cell lines by using electrophoretic mobility shift assays. (cdc.gov)
  • We performed binding assays by surface plasmon resonance to study the interaction between Gal-8 and the recombinant glycosylated ALCAM ectodomain or endogenous ALCAM from MDA-MB-231 breast cancer cells . (bvsalud.org)
  • Unlike typical immunoglobulin G (IgG)-mediated pemphigus, IgA pemphigus is characterized by tissue-bound and circulating IgA autoantibodies that target the desmosomal proteins of the epidermis. (medscape.com)
  • Histones are structural proteins that attach (bind) to DNA and give chromosomes their shape. (medlineplus.gov)
  • Changes in levels of binding proteins and, consequently, changes in bioavailable levels of hormones are well-known endocrine regulatory mechanisms. (medscape.com)
  • Antiandrogens bind to androgen receptors and competitively inhibit their interaction with testosterone and dihydrotestosterone. (medscape.com)
  • The albumin binding sites are found to possess different binding affinities and relative abundance leading to different total binding capacities. (lancs.ac.uk)
  • Here, coupled with Spike structural comparisons, we show that BA.2.12.1 and BA.4/BA.5 exhibit comparable ACE2-binding affinities to BA.2. (cdc.gov)
  • Methods Parental MUC1 antibody was tested in a binding competition assay alongside a benchmark identifying cleaved MUC-1. (bmj.com)
  • The assay for SVA-sperm binding with 125 I-SVA determined the IC 50 as being (3.89 ± 0.65) x 10 -5 M -1 , which is compatible with an apparent dissociation constant of (9.10 ± 0.02) x 10 -5 M -1 estimated by fitting the data of phosphatidylcholine-perturbed SVA fluorescence to a modified Scatchard plot. (tmu.edu.tw)
  • In the luciferase assay 4 of the 21 SNPs exhibited allele-dependent changes in gene expression. (cdc.gov)
  • The mAbs binding the C-terminal portion of the BoNT/A heavy chain had optimal properties for use in the Endopep-MS assay. (cdc.gov)
  • Here we show the first molecular view of reception of a taste substance by a taste receptor, where the binding of the taste substance elicits a different conformational state of T1r2/T1r3 LBD heterodimer. (nature.com)
  • Förster resonance energy transfer and X-ray solution scattering have revealed the transition of the dimerization manner of the ligand binding domains, from a widely spread to compactly organized state upon taste substance binding, which may correspond to distinct receptor functional states. (nature.com)
  • We mapped all estrogen receptor and RNA polymerase II binding sites on a genome-wide scale, identifying the authentic cis binding sites and target genes, in breast cancer cells. (nature.com)
  • Figure 1: Summary of estrogen receptor and RNA PolII binding sites and correlation with nucleotide and gene number. (nature.com)
  • Figure 2: Estrogen-mediated transcript changes and correlation with estrogen receptor binding. (nature.com)
  • Figure 3: Estrogen receptor and RNA PolII binding relative to specific gene targets. (nature.com)
  • Figure 4: Identification of enriched motifs within the estrogen receptor binding sites and validation of transcription factor binding. (nature.com)
  • Figure 5: Involvement of cooperating transcription factors at estrogen receptor binding sites. (nature.com)
  • Figure 7: Assessment of estrogen receptor binding properties in different cell systems. (nature.com)
  • In the version of this article initially published online, the estrogen receptor and RNA PolII binding data were aligned incorrectly in the top panel of Figure 3, which represents estrogen receptor binding at the ESR1 gene region. (nature.com)
  • [ 13 ] The hallmark finding in IgA pemphigus is autoantibodies binding to sites containing the monocyte/granulocyte IgA-Fc receptor (CD89), causing intraepidermal neutrophilic pustules. (medscape.com)
  • The heavy chain is responsible for both receptor some species of the genus Clostridium, in particular, Clostridium binding via its C-terminal (CT) binding domain [4,5] (HC) and botulinum, C. butyricum, C. baratii, and C. argentinense. (cdc.gov)
  • The new variants' receptor binding and immune evasion capability require immediate investigation. (cdc.gov)
  • Four variants exhibited effects on gene regulation (ATF rs11571537, CDH17 rs2446824 and rs2513789, and TACR1 rs2287231). (cdc.gov)
  • Covering the lives of nineteen enslaved individuals that lived at Mount Vernon, the Lives Bound Together exhibit sheds light on Washington's changing views towards slavery that led to him adding a provision to free his slaves after his death in his will. (virginia.org)
  • IFABP and the binding thermodynamics (Richieri growth and differentiation (Glatz & van der et al. (lu.se)
  • This exhibition of 37 bindings displays the 28 prizewinning bindings alongside 9 highlights by USA binders selected from the Third International Bookbinding Competition 2017. (nbss.edu)
  • This delightful exhibit displays selected artworks alongside Stevens' poems, pairing art with literature. (cf.edu)
  • This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. (nih.gov)
  • This and other exhibits within the library are generously supported by the McBrien Special Collections Endowment. (nd.edu)
  • Public tours of the Rare Books & Special Collections Fall Exhibit are offered every Wednesday at 12:15pm (except October 6). (nd.edu)
  • Curated exhibits highlight the historical and cultural impact of our collections. (smu.edu)
  • Quinolones are bactericidal and exhibit concentration-dependent killing. (cdc.gov)
  • A fifth variant (FAM71A rs147978008) showed nonrisk allele preferential binding to H1 histones. (cdc.gov)
  • The extracellular domain consists of the ligand binding domain (LBD), responsible for primary agonist binding, followed by the cysteine rich domain (CRD), which mainly serves as a linker between the LBD and the transmembrane region ( Fig. 1a ). (nature.com)
  • The SPD-type variant exhibits IgA autoantibodies targeting the transmembrane glycoprotein desmocollin 1 present within keratinocyte desmosomes. (medscape.com)
  • tance of these two bacteria exhibit very different patterns. (cdc.gov)
  • If you're a millennial like me, you might remember those colourful patterns exhibited on computer screens when playing music on certain programs. (thegatewayonline.ca)
  • Moreover, the SVA-sperm binding could be inhibited by the dispersed sperm lipid. (tmu.edu.tw)
  • 1994). High-res- belongs to the family of intracellular lipid bind- olution crystal structures (Sacchetti ni et al. (lu.se)
  • GnRH agonists bind to the GnRH receptors on pituitary gonadotropin-producing cells, causing an initial release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) and consequently a rise in testosterone levels for a few weeks. (medscape.com)
  • Altogether there is something comforting about the order and repetition found both in the auditory and visual aspects of the exhibit. (thegatewayonline.ca)
  • A complete list of the artists and works exhibited in the Palace of Fine Arts can be found here:[12] The Art Department's focus was on modern American painting, works painted in the 17 years since the 1876 Centennial Exposition. (wikipedia.org)
  • The N-terminal 216 amino acids of the mature SzM were found to exhibit a high degree of diversity, but the majority of human isolates grouped in three distinct SzM clusters. (lu.se)
  • The exhibit is set to run from January 27 to May 14, 2023 and will cost $5 for the special exhibit fee, in addition to general admission. (sugar-scoop.com)
  • Serum albumin binding to the yeast form of Candida albicans is described. (lancs.ac.uk)
  • Two populations of binding site are identified using two complementary spectroscopic techniques: An extrinsic fluorescent probe, 3-hexa-decanoyl-7-hydrocoumarin ([HEXCO) added to the C. albicans yeast cell surface that records the electrostatic surface potential and so responds to the surface binding of serum albumin and secondly a light scattering technique that reveals how albumin modulates aggregation of the yeast population. (lancs.ac.uk)
  • The Legacy Museum of African American History features exhibits about Central Virginia's Black history, from the first slaves that arrived in 1619 to present-day figures and events that have shaped the Commonwealth and the entire country. (virginia.org)
  • Chromosome 4 of Drosophila melanogaster is an atypical autosome, exhibiting several features characteristic of the X chromosome. (the-scientist.com)
  • The Neuropsychological Test for the Assessment of Visuospatial Binding (TNABV) was developed to measure the Working Memory binding for object-location features. (bvsalud.org)
  • During childhood they may exhibit features of autism or related developmental disorders affecting communication and social interaction. (medlineplus.gov)
  • Therefore, -lactam antibiotics, such as penicillin G, bind to PBPs in better understanding of S. pneumoniae resistance selection and the bacterial cell wall. (cdc.gov)
  • Candida albicans exhibit two classes of cell su. (lancs.ac.uk)
  • BSA01 BsAbs bound EGFR+MUC-1+ cell lines (HCC827 and HCC70) with stronger avidity than a single-positive cell line (A431). (bmj.com)
  • A computational model of master regulators that are required for successful reprogramming the dynamics of this core network has revealed that it functions as of a differentiated cell into a cell exhibiting stem cell like a bistable switch, which in the on state, corresponds to all these properties. (lu.se)
  • Glycosylation-dependent binding of galectin-8 to activated leukocyte cell adhesion molecule (ALCAM/CD166) promotes its surface segregation on breast cancer cells. (bvsalud.org)
  • Titled Misadventures of a 21st Century Naturalist , the exhibit represents the full range of his work, which varies widely in content but consistently reveals the ways in which we make sense (and nonsense) of the world around us. (forbes.com)
  • The British Library, Binding Index, lists [C. L. H.] L. Hay-Cooper, who worked with the binder S. Bernard. (antiqbook.com)
  • Each month our local history blogger, Kat Spitzer, takes readers on a trip to an exhibit in Anne Arundel County. (visitannapolis.org)
  • Its membership includes some of the most highly regarded makers in the fields of fine bookbinding, book arts and artists' books, each with a passion for presenting the bound text as a unique art object. (nbss.edu)
  • Artists from the United States and 19 foreign countries exhibited at the Exposition. (wikipedia.org)
  • Art juries had been directed to select a maximum of 3 works per artist, but exceptions were made for prominent artists-George Inness exhibited 15 paintings, Winslow Homer and D. W. Tryon each exhibited 14, Kenyon Cox and Robert Vonnoh each exhibited 13, Thomas Eakins exhibited 10 (plus another in the Pennsylvania State Building). (wikipedia.org)
  • The goal of this exhibit is two-fold: to bring together the work of our artists who design and make their own dolls and the work of our 2-d artists, challenging them to use dolls as their subject for a month. (ebsqart.com)
  • We examined its distribution in the accessory sexual gland, characterized its binding sites on the sperm surface and assessed its effect on sperm motility. (tmu.edu.tw)
  • Additional works-not in competition for medals-were exhibited in other Exposition buildings, including the Woman's Building and individual state buildings. (wikipedia.org)
  • These results suggest that SzM-mediated binding of human fibrinogen is an important virulence mechanism of zoonotic S. equi subsp. (lu.se)
  • We also analyzed the binding of ALCAM -silenced or control breast cancer cells to immobilized Gal-8 by SPR. (bvsalud.org)
  • Call or email us today to learn more about the comprehensive exhibit production services we offer to make your time in the courtroom a little easier. (alphagraphics.com)
  • Finitura's exhibit tabs are available for letter size (8.5" x 11") and legal size paper (8.5" x 14") with side or bottom tab styles. (finitura.com)
  • Finitura manufactures custom exhibit tabs and legal indexes to fit your company needs. (finitura.com)
  • Ideal for briefs, legal exhibits, mortgage documentation files and more! (superwarehouse.com)
  • Partner with the legal solutions team at AlphaGraphics, and we'll help you impress in court with sophisticated, attention-grabbing courtroom exhibits. (alphagraphics.com)
  • AlphaGraphics offers a broad range of large format and legal exhibit services. (alphagraphics.com)
  • A cytochemical study illustrated the presence of SVA-binding region on the entire cells. (tmu.edu.tw)
  • 184 binders from 31 countries took part binding a book of their own choosing on the theme of Myths, Heroes & Legends. (nbss.edu)
  • NEDCC's Associate Book Conservator Mary French highlights the conservation treatments of three unique books: a Victorian hair album, a medieval manuscript, and a Kashmiri birch bark binding. (nedcc.org)
  • Victorian Publishers Book-Bindings p130. (antiqbook.com)
  • The title of the exhibit within the gallery is uncapitalized. (thegatewayonline.ca)
  • Click any banner or title below to view one of our many monthly exhibits. (ebsqart.com)
  • Nr fine in an attractive maroon full-calf binding, with gilt title piece & spine decorated in blind and gilt. (antiqbook.com)
  • Nr fine in an attractive black full-calf binding, 2 title pieces, gilt and blind decoration. (antiqbook.com)
  • Three large parts from two solid rocket boosters are now on a cross country road trip in preparation for the planned 2019 exhibit at the California Science Center in Los Angeles. (collectspace.com)
  • Additionally, the museum exhibits look at famous Black Virginians. (virginia.org)
  • Honoring the birthplace of Booker T. Washington, America's most prominent Black educator, orator, and statesman of the late 1800s-1900s, the Booker T. Washington National Monument includes a Visitor's Center with exhibits on Washington's life and legacy, as well as a living history farm where visitors can learn about farm life in Civil War Virginia, the era during which Washington grew up. (virginia.org)
  • Exhibits showcase over 100 years of Black history in Martinsville and surrounding Henry County, as well as exhibits on a national level. (virginia.org)
  • All exhibits are free and open to the public during business hours . (nd.edu)
  • Only these fair maidens are bound by contact to marry their suitors if they open their eyes while being kissed. (odditycentral.com)
  • Common Ties That Bind , which will run from July 15 - August 23 in the Davis Gallery, uses bold and innovative visual language to explore timely topics of race, gender and other biases. (sawtooth.org)
  • Join College of Central Florida Associate Professor Tyrus Clutter at the Ocala Campus Webber Gallery for a discussion on collecting art on a budget followed by a public reception for the Greater than 17 art exhibit. (cf.edu)
  • This exhibit, we want to see your depictions of real flower species that are naturally blue. (ebsqart.com)