• The aim of this study was to identify susceptibility variants of CACNA1A, POMP, TMEM136, AGPAT1, RBMS3, and SEMA6A genes for Exfoliation Syndrome (XFS) and Exfoliation Glaucoma (XFG) by a case-control association study approach among Georgian population. (cdc.gov)
  • The risk conferred by these variants is such that it accounts for virtually all cases of exfoliation glaucoma, meaning that if we can neutralize the impact of these variants we might eliminate the disease. (innovations-report.com)
  • Science DOI: 10.1126/science.From the abstract of this study: "Approximately 25% of the general population is homozygous for the highest risk haplotype and their risk of suffering XFG (exfoliation glaucoma) is over 100 times that of those only carrying low-risk haplotypes. (snpedia.com)
  • The identification of a new clinical sign for exfoliation syndrome may provide patients and their doctors with a powerful and benign predictive test for exfoliation syndrome that can help with diagnosis and management of this important eye disease. (glaucoma-genetics-lab.org)
  • These are previously unappreciated clinical signs that may aid in the early diagnosis of Coffin-Lowry syndrome. (nih.gov)
  • The diagnosis of staphylococcal scalded skin syndrome was reached on clinical grounds and culture report. (tripdatabase.com)
  • Having a high clinical suspicion for staphylococcal scalded skin syndrome , early diagnosis/treatment, and following robust hygiene measures are imperative for the effective management of staphylococcal scalded skin syndrome . (tripdatabase.com)
  • This diagnosis should be made carefully, because scalded skin syndrome may be mistaken for erythema multiforme or toxic epidermal necrolysis, which can be treated with corticosteroids. (medscape.com)
  • KarthikeyanArcotSadagopan, Renukadevi Kathirvel, Rosanne B. Keep, P. Sundaresan, Hui Huang, Arndt Rolfs, KannanParthiban& P. Vijayalakshmi "Cutaneous freckling: Possible new clinical marker for the diagnosis of Hermansky-Pudlak syndrome in Indian Asian patients with oculocutaneous albinism" Ophthalmic Genet. (aravind.org)
  • A sharp increase in staphylococcal scalded skin syndrome (SSSS) cases has been recorded in our settings since 2015, with 31 cases having been documented during the period 2014-2017. (tripdatabase.com)
  • This may be one of the predictable causes for delayed exfoliation of primary teeth . (symptoma.com)
  • The dental manifestations are mainly delayed exfoliation of primary teeth and delayed eruption of permanent teeth, with multiple impacted supernumeraries. (symptoma.com)
  • Failure of exfoliation of primary teeth . (symptoma.com)
  • [nejm.org] The failure of primary teeth to exfoliate on time had not previously been found to be associated with the hyper-IgE syndrome. (symptoma.com)
  • [ncbi.nlm.nih.gov] The dental indicators are principally delayed exfoliation of primary teeth and delayed eruption of permanent teeth, and numerous impacted supernumeraries. (symptoma.com)
  • The 2019 Think Tank, the seventh dealing with exfoliation, will convene in New York City in June, once again providing a unique opportunity for scientists and clinicians from a variety of disciplines and numerous countries to apply their research and expertise to the challenge of glaucoma. (campaign-archive.com)
  • However, until recently, this type of iris defect (Marcel iris trans-illumination defect) had not been prospectively tested to see if it is a specific clinical sign for exfoliation syndrome. (glaucoma-genetics-lab.org)
  • These "new" clinical manifestations expand the phenotype of Coffin-Lowry syndrome and constitute an additional indication of pleiotropy. (nih.gov)
  • Ease of hydrodissection during phacoemulsification: a comparison between patients with and without exfoliation syndrome. (physiciansweekly.com)
  • Exfoliation syndrome is a common condition in which a flaky white material is deposited in many tissues of the eye (the lens, the cornea, and the drainage structures) and throughout the body. (glaucoma-genetics-lab.org)