• No significant difference has been found in the rate of its urinary excretion in frequent and infrequent users, but half-life of THC-COOH in urine in the first days is different compared with a later period. (cleanandhealthyme.org)
  • Excretion: The majority was excreted via urine. (europa.eu)
  • This was indicated by excretion of up to 98% of the dose administered (maximum for C12AS Na) in the urine and by comparison of excretion after oral and i.v. or i.p. application for several alkyl sulfates. (europa.eu)
  • The excretion of 14C-labelled test substance was studied using collected samples of urine, faeces and bile by thin layer chromatography and radioassay. (europa.eu)
  • Excretion study: Urine and faeces were collected at 4 h intervals for 3 d. (europa.eu)
  • For the study of the excretion of 14C-labelled compounds, similarly treated animals were kept in metabolism cages permitting the separate collection of urine and faeces, which were removed at 4 h intervals for a period of 3 days and kept refrigerated until examined. (europa.eu)
  • After single intravenous administration of [ 3 H] caspofungin acetate, excretion of caspofungin and its metabolites in humans was 35% of dose in feces and 41% of dose in urine. (theodora.com)
  • the use of drugs that increase urine excretion (diuretics), profuse sweating (for example, during heat waves, particularly with prolonged exertion), and decreased water intake can lead to dehydration. (msdmanuals.com)
  • can increase the excretion of urine and thereby lead to dehydration. (msdmanuals.com)
  • No metabolite of adipic acid could be detected in the urine (Lang & Bartsch, 1953). (inchem.org)
  • 2 ) The primary carboxylated metabolite is 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH), which is the predominant metabolite in urine and the target substance in urine drug testing. (cleanandhealthyme.org)
  • Since THC-COOH is the prevalent metabolite excreted in urine, checking it is most advisable for detecting cannabis use, so all urine tests for marijuana look for THC-COOH, not THC itself. (cleanandhealthyme.org)
  • Urea is excreted by the kidneys. (medlineplus.gov)
  • The test measures the amount of urea the kidneys excrete. (medlineplus.gov)
  • More recent at- ry or other pathologic changes except for occasional depos- tempts in which urine from infected hamsters was injected its of disease-associated prion protein in kidneys. (cdc.gov)
  • the source of TSE infectivity in urine remains unresolved, Two other studies have reported infectivity in urine ( 11 ) these results establish that TSE infectivity is excreted in and infectivity with disease-specifi c prion protein (PrPd) in urine and may thereby play a role in the horizontal transmis- kidneys of mice with simultaneous scrapie and nephritis but sion of natural TSEs. (cdc.gov)
  • Primary hyperoxaluria type 1 (PH1) is an extremely rare hereditary condition that is characterized by excessive oxalate formation -a waste product usually removed by the kidneys and discharged in the urine. (medicinenet.com)
  • Normally, oxalate is filtered by the kidneys and excreted in the urine. (medicinenet.com)
  • These two tyrosine derivatives are found only in urine, suggesting rapid clearance of these derivatives by the kidneys. (theodora.com)
  • After 10 to 12 days, virus is present in blood and is excreted via the biliary system into the feces. (cdc.gov)
  • Most infected persons no longer excrete virus in the feces by the third week of illness. (cdc.gov)
  • 3 ) More than 65% of THC and its metabolites is excreted in feces and about 20% in urine. (cleanandhealthyme.org)
  • In one study, plasma, urine, and feces were collected over 27 days, and in the second study plasma was collected over 6 months. (theodora.com)
  • Senior Monsanto scientist (forgive me if "Monsanto scientist" seems like a contradiction in terms) Dan Goldstein even recently stated, "If ingested, glyphosate is excreted rapidly, does not accumulate in body fat or tissues, and does not undergo metabolism in humans. (truthout.org)
  • Varenicline undergoes minimal hepatic metabolism and is excreted largely unchanged in the urine. (nih.gov)
  • Some heavy marijuana users with slow metabolism were found to excrete THC metabolites much more slowly than others and have unusually long THC-COOH half-life. (cleanandhealthyme.org)
  • Urine urea nitrogen is a test that measures the amount of urea in the urine. (medlineplus.gov)
  • in addition other radioactive substances (urea, glutamic acid, citric acid and -keto adipic acid) were found in the urine (Rusoff et al. (inchem.org)
  • She stopped the medication promptly but during the next week developed itching, dark urine, and jaundice. (nih.gov)
  • of the dose in the urine in 4 days (Enders, 1941). (inchem.org)
  • Less than 0.4% of a 3 μ mol dose of 35S-labeled C12 ASO4Na was percutaneously absorbed in guinea pigs, based on recovery of the radiolabel in urine, faeces and expired air. (europa.eu)
  • A small amount of caspofungin is excreted unchanged in urine (~1.4% of dose). (theodora.com)
  • 30% of the administered dose was excreted in urine as unchanged drug. (lu.se)
  • Hyperoxaluria is a condition in which the urine contains an excessive amount of oxalate. (medicinenet.com)
  • A condition in which the urine has more than normal amounts of a protein called albumin. (diabetes.org)
  • Histologic and immunohistochemical examination by cross-species inoculation of rodents and primates with of these same tissues showed no indications of infl ammato- urine from diseased patients failed ( 7,8 ). (cdc.gov)
  • Urine was collected from a cohort of 22 Syrian ham- of infectivity found in tissues outside the nervous system. (cdc.gov)
  • Once THC enters the body, most of it turns into metabolites, which are distributed to various tissues and can be detected in blood, saliva, sweat, urine, and hair. (cleanandhealthyme.org)
  • In humans, a long asymptom- infectivity in urine of scrapie-infected hamsters. (cdc.gov)
  • When apo(a) fragments purified from human plasma were injected intravenously into mice, a species that does not produce apo(a). apo(a) fragments similar to those found in human urine were readily detected in mouse urine. (elsevierpure.com)
  • Most opioids are metabolized by hepatic conjugation to inactive compounds that are excreted readily in the urine. (medscape.com)
  • Another study found that THC-COOH concentrations in urine of marijuana smokers drop rapidly only until they reach a level of 20-50 ng/ml. (cleanandhealthyme.org)
  • Neither substance as a tendency to bioaccumulate, both are rapidly excreted. (europa.eu)
  • Only smaller amounts are excreted via the faeces. (europa.eu)
  • Diuretics are medications that increase urine production and can affect the levels of certain drugs in the body, including gentamicin. (proprofs.com)
  • Small amounts of adipic acid have been frequently found in the normal human urine (Hanson, 1943). (inchem.org)
  • At least 80% of these compounds are metabolized in the body and excreted by urine. (hindawi.com)
  • Children were clinically examined for goitre, urine and household salt samples were collected to estimate urinary iodine concenteration (UIC) and iodine content in salt. (who.int)
  • A chemical found only in breast milk can break tumours into tiny fragments that cancer patients can pass in their urine, research suggests. (dailymail.co.uk)
  • All 20 patients who received the breast milk chemical passed tumour fragments in their urine. (dailymail.co.uk)
  • The THC levels that create impairment are not well understood and according to the NIDA, there is wide variability in how THC is metabolized by frequent users versus infrequent users which makes interpretation of a positive urine drug test a challenge (10). (cdc.gov)
  • Instead, the extra vitamin C is excreted in urine. (webmd.com)
  • Previously, we showed that kringle 4-containing fragments of apo(a) are present in human urine. (elsevierpure.com)
  • One study found 20 bladder cancer sufferers excreted tumour fragments in their urine after just six infusions of alpha1H. (dailymail.co.uk)
  • Tell your doctor if you experience serious side effects of D.H.E. 45 including slow/fast/irregular heartbeat, tingling/pain/coldness in the fingers or toes, whitish fingers/toes/nails, loss of feeling in the fingers or toes, bluish hands or feet, muscle pain or weakness in the arms or legs, severe stomach or abdominal pain, lower back pain , or little or no urine. (rxlist.com)
  • Urine was Tissue Collection and Processing maintained at 4oC during collection. (cdc.gov)
  • The acid mucopolysaccharides are stored in tissue and excreted in large quantities in the urine. (nih.gov)
  • Tests are available to measure levels of pentachlorophenol and its breakdown product in blood, urine, and fat. (cdc.gov)
  • Symptoms of the disease include blood in the urine, needing to urinate more often or more urgently than normal and pelvic pain. (dailymail.co.uk)
  • A recent study of non-farmworker, urban dwellers in Germany found glyphosate in the urine of every person tested, and at levels five to 20 times the legal limit for drinking water. (truthout.org)
  • The urine pro- or 76 days postinoculation. (cdc.gov)
  • A dog given a total of 23.1 g of disodium adipate during 3 days excreted 58 per cent in the urine (Verkade et al. (inchem.org)
  • Four rabbits given 4-6 g adipic acid excreted 57 per cent. (inchem.org)
  • To investigate urine as a potential human urine, which is a source of injectible fertility hor- source of TSE exposure, we used a sensitive method for mones and other drugs ( 5,6 ), could also pose a risk for trans- detection and quantitation of TSE infectivity. (cdc.gov)
  • To resolve these dis- for TSE transmission from human urine-derived hormones crepancies, we used a highly sensitive and precise method and other medicines. (cdc.gov)
  • Short-chain PFAS are excreted more quickly after being absorbed by the human and mammalian organism than those with longer carbon chains. (bund.de)
  • an extensive work-up was conducted and the results revealed that Ms. Chapman apparently been excreting Lyme [spirochetes] in her urine. (angelfire.com)
  • Only a small fraction is excreted unchanged in the exhaled air [ 5 ]. (hindawi.com)
  • A 24-hour urine sample is often needed. (medlineplus.gov)
  • Urine sample preparation for the analysis of hydroxyl-PAHs metabolites included enzymatic digestion, solid phase extraction, and isotope dilution GC/MS and microflow LC-Q-TOF MS detections. (cdc.gov)
  • Not surprisingly, urine testing of US residents showed levels 10 times higher than those of European residents. (truthout.org)
  • Lab Products, Sea- each of 12 infected animals that donated urine either 71 ford, DE, USA) were used for each cohort. (cdc.gov)