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  • AMPA
  • These results suggest that the activation of postsynaptic AMPA receptors is necessary to produce TTX-resistant synchronized discharges. (jneurosci.org)
  • Predictions were made for passive-cell current clamp recordings, combined AMPA and NMDA receptor responses, and local dendritic depolarization in response to unitary stimulations. (springer.com)
  • interneurons
  • They are composed of variables and parameters describing the local spatiotemporal mean activity of two subclasses of neurons - excitatory principal cells (PCs) and inhibitory interneurons (INs) - without referring to the biophysical details of individual cells. (scholarpedia.org)
  • These findings prioritize the loss of granule cell layer interneurons for further testing as a potential cause of temporal lobe epilepsy. (stanford.edu)
  • We tested this hypothesis in mice by in vivo unilateral epileptogenic hippocampal kainate lesion followed by in vitro recording of extracellular potentials and patch-clamp from GFP-expressing interneurons in CA3, in an optimized recording chamber. (frontiersin.org)
  • pathways
  • The three sensory pathways described above (especially vision) are perhaps the best studied, but other thalamic nuclei receive subcortical input, project to cortex, and are innervated by cortex. (scholarpedia.org)
  • distinct
  • To illustrate its unifying potential, this simple model is applied to two very distinct biological processes - the spontaneous activity of the human cortex (i.e. when subjects are at rest), and genetic regulation in a bacteriophage. (plos.org)
  • excitation
  • Experimental work using pharmacological manipulations of the in vitro hippocampal slice preparation found that the 40 Hz-range field potential oscillations evoked under different circumstances exhibited different reliance on synaptic excitation and inhibition. (jneurosci.org)
  • describe
  • In the literature, discussion of different regions of thalamus uses the terms primary sensory, or 'specific' to describe the thalamic nuclei or regions that receive direct excitatory input from the periphery, eg. (frontiersin.org)
  • In this review, the term 'primary sensory' is used to describe those thalamic regions that receive sensory input directly from the periphery. (frontiersin.org)
  • thalamic
  • Those thalamic nuclei in turn project topographically to well-defined architectonic fields of cortex, which reciprocally project back topographically to their innervating thalamic nuclei. (scholarpedia.org)
  • From a given thalamic nucleus, core cells project topographically to a sharply bounded, associated architectonic field of cortex. (scholarpedia.org)
  • brain
  • Mean field models are based on the evidence of redundancy at small volumes within brain tissues as neurons within these volumes respond in similar fashion to identical stimuli. (scholarpedia.org)
  • Indeed, while the physical foundations of LFPs are well known ( Nunez and Srinivasan, 2006 ), the complex geometry of the sources of these potentials in the brain cast important technical limitations to understand their cellular basis. (frontiersin.org)
  • sensory
  • Regions that receive sensory input indirectly, via the cortex, have often been rather loosely termed 'non-specific' or association regions. (frontiersin.org)
  • American gymnotiformes and African mormyriformes have evolved an active sensory system using a self-generated electric field as a carrier of signals. (oxfordre.com)