Glycine is an amino acid, or a building block for protein. (supplemented.co.uk)
Glycine is an amino acid and neurotransmitter. (examine.com)
[1] Glycine is the simplest amino acid in nature, with a single hydrogen atom as its side chain. (examine.com)
Glycine is the primary amino acid in collagen, making up one-third of its amino acids in the repeated form of tripeptides (glycine-proline-Y and glycine-X-hydroxyproline, where X and Y can be any amino acid). (examine.com)
[5] Like all amino acids, glycine has a central carbon with one amino group, one carboxy acid group, and one side chain that makes each amino acid unique. (examine.com)
For glycine, this side chain is a single hydrogen atom, which is why glycine is the simplest and smallest amino acid in nature. (examine.com)
Glycine is a nonpolar neutral amino acid, meaning it has no net electrical charge and does not interact with water. (examine.com)
As an amino acid, glycine plays an essential role in protein synthesis, especially collagen synthesis. (examine.com)
[12] Additionally, glycine is conjugated with bile acids (along with taurine) before being excreted into the biliary system, thereby playing a central role in lipid digestion and absorption. (examine.com)
Glycine acts as both an inhibitory and excitatory neurotransmitter in the brain and spinal cord, where it is involved in reflex coordination, the processing of sensory signals, and the sensation of pain. (examine.com)
Glycine also functions as both an inhibitory and an excitatory neurotransmitter, functions as a signaling molecule in the immune system, is necessary for the proper function of some enzymes, and plays a role in lipid digestion and absorption. (examine.com)
Glycine is a conditionally essential amino acid in humans because humans are unable to synthesize enough glycine to satisfy metabolic requirements. (examine.com)
Neurotransmitter1
Excitatory amino acid transporters (EAATs) of the solute carrier family 1A (SLC1A) take up the neurotransmitter L-glutamate from the synaptic environment, which is necessary to keep the extracellular concentration low and prevent neurotoxicity 1 , 2 . (nature.com)
Inhibitory2
Consistent with this, in vivo recording showed that nociceptive-evoked responses of ON- and OFF-cells were suppressed by optogenetic inactivation of archaerhodopsin (ArchT)-expressing PB terminals in RVM, demonstrating that a net inhibitory input to OFF-cells and net excitatory input to ON-cells are engaged by acute noxious stimulation. (eneuro.org)
It receives excitatory input from rod bipolar cells and sends its output to ON-cone bipolar cells via electrical synapses, and to OFF-cone bipolar cells via glycinergic, inhibitory synapses (Bloomfield & Dacheux, 2001). (gasyblog.com)
Hydrolysis2
Gly ) is a conditionally essential amino acid discovered in 1820 by French chemist Henri Braconnot through acid hydrolysis of gelatin. (examine.com)
Phospholipases A 2 (PLA 2 ) form a superfamily of enzymes that catalyze production of lyso-phospholipids and free fatty acids by the hydrolysis of phospholipids sn-2 ester bond. (pharmaceuticalintelligence.com)
Peripheral1
The peripheral administration of kynurenic acid (KYNA) precursor, kynurenine (KYN) was found to lead to neuroprotection in hypoxic-ischemic animal models [ 1 ] . (encyclopedia.pub)
Proteins2
L-Aspartic acid is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. (sigmaaldrich.com)
Oppositely oriented Glt Tk proteins showed the same transport kinetics, consistent with the use of an identical gating element on both sides of the membrane. (nature.com)
Reactions1
1984. Kinetics and mechanisms of the gas-phase reactions of ozone with organic compounds under atmospheric conditions. (cdc.gov)
Input1
We hypothesize that glycinergic synaptic input may target the arboreal dendrites of AII cells, and could serve to shunt excitatory input from rod bipolar cells and transiently uncouple the transcellular current through electrical synapses between AII cells and between AII cells and ON-cone bipolar cells. (gasyblog.com)
Found1
This amino acid is found in high-protein foods including meat, fish, eggs, dairy and legumes. (supplemented.co.uk)