Excipients in pharmaceutical preparations. Medical search. Frequent questions

VitiPure L 20 can be used in various pharmaceutical formulations. (clariant.com)
Our Excipients are used in drug formulations as Emulsifiers, Rheology Modifiers, Binders, Humectants, Plasticizers etc. for all sorts of pharmaceutical dosage applications. (clariant.com)
Analyze your powder formulations and ensure you set the right preparation conditions. (anton-paar.com)
The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. (gc.ca)
The CQAs are not only the key properties of formulations, which affect the quality of preparations, but also the key parameters for evaluating preparation. (hindawi.com)
Povidone is one of the most common and widely used excipients in pharmaceutical formulations.It is usually used as a favourite binder in tablet and capsule manufacturing because of its ability to dissolve in water as well as in IPA. (pharmainform.com)
Povidone is an example of synthetic binders used in pharmaceuticals formulations. (pharmainform.com)

The focus was on the small (n=12), phase 1 study results for BIOD-238 and BIOD-250, combinations of Biodel's proprietary excipients with the marketed formulation of Humalog. (closeconcerns.com)
Pharmaceutical technology 1 education is focused on dosage forms formulation with emphasis on their classification, properties and the use of excipients, elucidating composition and structure of dosage forms in technological and biopharmaceutical context. (cuni.cz)
Included here are materials used in the preparation and/or formulation of the finished dosage form. (drugbank.com)
Additionally, the surface area and porosity of a powder pharmaceutical formulation provide even more insight, particularly into solubility and dissolution rates. (anton-paar.com)
Uses of Cold Cream , Formulation of Cold Cream , Preparation of Cold Cream , Tests of Cold Cream , History and Ideal properties of cold cream . (pharmaeducation.net)
When formulating the formulation, it is necessary to understand the interaction between excipients and excipients, and between excipients and drugs through preliminary investigations to avoid choosing inappropriate excipients. (medicilon.com)
Drug molecules and excipient molecules often adsorb to each other through van der Waals forces or electrostatic interactions, thereby effectively improving the solubility and lubricity of the drug formulation, and improving the quality of the drug. (medicilon.com)
In tablets, the small drug molecules and the large molecules on the surface of the excipients are often combined by adding excipients to obtain a uniform and stable formulation. (medicilon.com)
The inherent binding and disintegration properties of the compressed Cop-MC are useful for the formulation of poorly compressible, high strength, and lowstrength active pharmaceutical ingredients. (gre.ac.uk)
IGDRASOL's lead therapeutic platform is Cynviloq, a branded micellar paclitaxel formulation which is free of cremophor and human serum albumin (HSA), the excipients for Taxol® (cremophor-based paclitaxel) and albumin-bound paclitaxel (Abraxane®), respectively. (biospace.com)

Our Life Science business supports the registration of APIs and excipients in the US, EU, ICH-region and emerging countries, including preparation and submission of: US Drug Master Files (DMF), EU-ASMF (Active Substance Master Files), CEP dossiers and other Master Files to competent authorities. (sigmaaldrich.com)
The latest revised China Drug Administration Law enforced the implementation of the Marketing Authorization Holder system, as well as the co-review regulation relevant for APIs, excipients and packaging. (sigmaaldrich.com)
Many of our excipients and APIs are already registered with the CDE. (sigmaaldrich.com)
Customers who require a Letter of Access to refer to any of our registered excipients or APIs in their drug application should contact their local sales representative. (sigmaaldrich.com)
Our experts effectively and efficiently supported the risk assessment of APIs and Excipients and have made assessment statements available to be used by customers via the Emprove ® Dossiers. (sigmaaldrich.com)
Neusilin® is a multi-functional excipient that solves common problems associated with tableting by facilitating improved and consistent flow of powder mix, providing optimum tablet hardness at low compression forces, protecting the active ingredient from moisture related issues, enhance solubility of poorly soluble APIs and converting oily or sticky APIs into free flowing powder. (pharmaexcipients.com)

The pharmaceutical excipients themselves are not completely inert, and their own functional groups or impurities may physically and chemically react with the active ingredients of the drug, thereby affecting the safety, effectiveness and quality controllability of the drug. (medicilon.com)
Ion chromatography is the method of choice to determine active ingredients, excipients and traces of impurities and metabolites in the form of organic and inorganic ions or polar substances in a number of pharmaceuticals, pharmaceutical solutions or body fluids. (pharmaceutical-technology.com)
In particular, Metrohm ion chromatography systems handle demanding analytical challenges such as the determination of impurities in pharmaceuticals, active pharmaceutical ingredients and pharmaceutical solutions. (pharmaceutical-technology.com)

AAM showed a good compactability and compressibility characteristics for tablets preparation. (bvsalud.org)
Pharmaceutical companies also provide an improved grade of isomalt offering interesting options in formulas for tablets and granulation. (yellowpages.ae)
Autopsies have found that crospovidone (PVPP) contributes to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. (wikipedia.org)
Production of Zinc Tablets and Zinc Oral Solutions: Guidelines for Programme Managers and Pharmaceutical Manufacturers to be used in infant treatment programmes. (who.int)
In the absence of pure pharmaceutical raw material, the feasibility study (Good Preparation Practices) revealed crushability of the available tablets. (bmj.com)
Pharmaceuticals Industry : Used as an excipient for the preparation of effervescent tablets. (xuerunchem.com)
Takeda Pharmaceuticals launched Takelda combination tablets, a fixed-dose combination of low-dose ASP and lansoprazole (LAN) [ 9 ]. (ijpsonline.com)

In this edition, a comparison of the production, use and properties of natural and synthetic phospholipids as pharmaceutical excipients is made by Hoogevest and Wendel. (ddw-online.com)

The pharmaceutical industry includes it in the composition of many drugs and excipients, to improve taste, color, texture, etc. (botanical-online.com)
It is one of the basic ingredients in the preparation of drugs for constipation . (botanical-online.com)
In 2019, China implemented an extensive overhaul of the regulatory requirements for drugs, resulting in a revised China Drug Administration Law, with an impact on domestic as well as foreign players in the Chinese pharmaceutical sphere. (cargill.com)
Solid density is an important property of pharmaceutical powders - drugs or excipients. (anton-paar.com)
Furthermore, in silico molecular docking studies were also performed to evaluate any probable molecular interactions among drugs and excipients using Auto Dock VINA 1.2.0 software and GROMACS 5.0 software. (ajbps.org)
In pre-prescription research, studying the compatibility of drugs and excipients can provide useful information and references for the selection of excipients in the prescription. (medicilon.com)
for the excipients that are not used in the prescriptions recorded in the inserts of the marketed drugs, it is recommended to conduct an excipient compatibility test. (medicilon.com)
The excipients that need to be investigated and the drugs are separately mixed and then tested for compatibility in order to discover the interaction between the drugs and the excipients. (medicilon.com)
What are the possible interactions between drugs and excipients? (medicilon.com)
With regard to the quality and safety of drugs, authorities worldwide set high standards for the pharmaceutical industry. (pharmaceutical-technology.com)

lists a wide range of active substances and excipients used to prepare pharmaceutical products. (lu.se)
The Regional Committee is invited to advise on the adoption of the attached draft guidelines on Stability Testing of Active Substances and Pharmaceutical Products in countries of the Eastern Mediterranean Region. (who.int)
These guidelines are intended to define the stability data package for active substances and pharmaceutical products that is sufficient for a registration application within countries of the World Health Organization's Eastern Mediterranean Region [1]. (who.int)
The guidelines address the information to be submitted in applications for registration of New Chemical Entities as well as existing active substances and their related pharmaceutical products for human use. (who.int)

C✩PharmGel ® 03406 & 03302 native maize starch - Excipients (EXC) for use as a binder, diluent or disintegrant in solid dosage forms. (cargill.com)
Maize starch provided by pharmaceutical companies was among the first excipients used in the preparation of pharmaceutical dosage forms. (yellowpages.ae)
The pharmaceutical companies in UAE offer a variety of types of maize starch. (yellowpages.ae)

Flowability, solubility, consistency, purity, and stability are parameters to be considered when it comes to optimizing pharmaceutical powders. (anton-paar.com)
The use of inactive and non-toxic excipients can effectively improve the appearance and compliance of the drug, but the active ingredients in the drug are likely to interact with the excipients, which may cause the drug Low availability or interfere with the stability of pharmaceutical preparations. (medicilon.com)
The main purpose of the study on compatibility of raw materials and excipients is to select excipients that can endow the drug substance with good bioavailability and manufacturability without affecting the stability of the drug substance. (medicilon.com)
Medicilon can undertake a full set of preparation research (including research and development, clinical sample production, stability), safety evaluation, packaging material compatibility, filter membrane verification, packaging sealing, pre-BE and BE research and other services to meet all your needs for on-site preparation development services. (medicilon.com)
The purpose of stability testing is to provide evidence on how the quality of an active substance or pharmaceutical product varies with time under the influence of a variety of environmental factors such as temperature, humidity and light. (who.int)

The flowability of a powder, in particular of an additive or excipient, is important in determining how that additive will affect the granulation or tableting process. (anton-paar.com)
A co-processed excipient was prepared from commercially available crystalline mannitol and α-chitin using direct compression as well as spray, wet, and dry granulation. (gre.ac.uk)
Optimal physicochemical properties of the excipient, from a manufacturing perspective, were obtained using a co-processed mannitol chitin (2:8, w/w) mixture prepared by wet granulation (Cop MC). (gre.ac.uk)

This e-book, focused on pharmaceutical powder characterization and containing real measurement data, tells you how to deal with pharmaceutical powder challenges such as flowability, solubility, and consistency under real-life conditions. (anton-paar.com)

Different spectroscopy techniques were utilized to see the interaction of GCV with excipients such as lactose, microcrystalline cellulose (MCC), magnesium stearate, and talc, and dicalcium phosphate. (ajbps.org)
In vitro dissolution studies in different sets of experiments were accomplished to determine the influence of hydrophobic and hydrophilic attributes of excipients (MCC, lactose, dicalcium phosphate, and talc) on the dissolution profile of GCV using USP1-type dissolution apparatus. (ajbps.org)
Excipient (lactose) was added if required. (bmj.com)

The sorbitol crystal is an exclusive excipient that allows tablet compression directly. (yellowpages.ae)
Porosity is also important in preventing excipient fracture during tablet compression. (anton-paar.com)
Commonly used sample preparation methods for IR spectroscopy include KBr compression, paraffin paste, diffuse reflection and attenuated total reflection (ATR). (formulationbio.com)

In the development of orally sustained and controlled release drug delivery system, due to the lower cost, safety, easy production and other factors, various cellulose derivatives are widely used in the preparation of sustained-release dosage forms, of which cellulose ethers are the most commonly used water-soluble and swellable polymers. (celluloseether.com)
The Role of Polymers and Excipients for Better Gastric Retention of Captopril. (ouhsc.edu)

C✩PharmDex ® 02010 dextrose monohydrate - Active Pharma Ingredient (API) for use as a carbohydrate source and osmotic agent in parenteral applications and oral preparations. (cargill.com)

They also facilitate trade in pharmaceuticals because they reduce costs for manufacturers by reducing the number of inspections taking place at facilities and waiving re-testing of their products upon importation. (europa.eu)
One of the consequences of this and subsequent changes to China pharmaceutical legislation, is that the NMPA (Chinese health authority) requires the submission of, and the pre-approval of, Drug Master Files (DMF) for ingredients and components of pharmaceutical (drug) products - including Active Pharmaceutical Ingredients (API), Excipients (EXC) and packaging materials. (cargill.com)
The wholesalers have recognized that in addition to high standard products, trust and commitment are essential to ensure a reliable supply to pharmaceutical companies. (yellowpages.ae)
The renowned companies' natural excipients collection provides key functionalities for various pharmaceutical products. (yellowpages.ae)
What Do Sorbital Pharmaceutical Products Function For? (yellowpages.ae)
In UAE, many renowned pharmaceutical companies have been established since the use of pharmaceutical products is increasing day by day. (yellowpages.ae)
Discover the leading companies here dealing in various best pharmaceutical products at the best prices. (yellowpages.ae)
You can rely upon these pharmaceutical products manufacturers & suppliers since only the verified contacts are registered with the portal. (yellowpages.ae)
According to Regulation No.146, issued by the former China Food and Drug Administration (CFDA) that is now known as the National Medical Products Administration (NMPA), an API or excipient manufacturer shall submit a technical dossier to the NMPA to obtain a registration number. (sigmaaldrich.com)
The presence of nitrosamines in pharmaceutical products has emerged as a public health concern, leading health authorities to provide guidance for Marketing Authorization holders and manufacturers alike to perform risk assessments and implement mitigation strategies in case of possible contamination. (sigmaaldrich.com)
Moreover, lipids are successfully used in pharmaceutical products to treat diseases. (ddw-online.com)
The practical training enable students to gain the basic skills necessary for compounding of preparations in pharmacies as well as in the large-scale manufacturing and the evaluation of properties of pharmaceutical products. (cuni.cz)
Comprehensive integration of pharmaceutical R&D supporting products. (formulationbio.com)
850 Professional IC with 858 Professional Sample Processor: an intelligent ion chromatography system for parallel determination of anions and cations in pharmaceutical products. (pharmaceutical-technology.com)
Discover what solutions Metrohm is able to offer the pharmaceutical sector, and you in particular, to ensure the quality and safety of your products. (pharmaceutical-technology.com)
According to Article 2 of the WHO Constitution, WHO is required to "develop, establish and promote international standards with respect to food, biological, pharmaceutical and similar products. (who.int)
Requirements for Registration of Pharmaceuticals for Human Use, European Agency for the Evaluation of Medicinal Products, and Gulf Cooperation Council. (who.int)

NAME OF THE MEDICINAL PRODUCT Sammibi 1 mg kit for radiopharmaceutical preparation. (studylib.net)
3. PHARMACEUTICAL FORM Kit for radiopharmaceutical preparation. (studylib.net)
The texts also cover dosage forms and containers, and biologicals, blood and plasma derivatives, vaccines and radiopharmaceutical preparations. (lu.se)

Preparation and evaluation of a new nano pharmaceutical excipients and drug delivery system based in polyvinylpyrrolidone and silicate. (bvsalud.org)
Volume I contains monographs of Chinese material medica and pared slice, vegetable oil/fat and its extract, Chinese traditional patent medicines, single ingredient of Chinese crude drug preparations etc. (wikipedia.org)
Carrageenan is used by the pharmaceutical and drug industry to make inactive excipients during tablet preparation, which has rendered it sufficient importance. (futuremarketinsights.com)
In Allen, Loyd V. . Pharmaceutical dosage forms and drug delivery systems . (cuni.cz)
Accurately measuring the particle size as well as the surface area and porosity of pharmaceutical powders is critical for optimizing drug consistency and delivery. (anton-paar.com)
In vitro study of a physical mixture of GCV with excipients was performed to get the release of drug. (ajbps.org)
Biomedical and pharmacological database contains drug and pharmaceutical research, pharmacology and toxicology. (monash.edu)
However, there is usually an embedding effect between the drug and the excipient in the tablet. (medicilon.com)
In-line quantification of drug and excipients in cohesive powder blends by near infrared spectroscopy. (formulationbio.com)

It is also used to form the cover of some preparations such as suppositories, pessaries or gels. (botanical-online.com)

A synthetic magnesium aluminometasilicate (MAS) with exceptional excipient properties for improving actives delivery and quality of pharmaceutical preparations. (pharmaexcipients.com)

A wide range of analytical instrumentation focused on pharmaceutical powder characterization under authentic conditions will help you hone the efficacy of the product. (anton-paar.com)
Download the e-book, "The Field Guide to Pharmaceutical Powder Characterization," and find out more. (anton-paar.com)
Determining temperature/humidity-dependent powder rheological properties enables the characterization of flow and mechanical behavior of pharmaceutical powders. (anton-paar.com)

It is commonly mixed with sodium bicarbonate and is sold as baking powder used as a leavening agent in food preparation. (xuerunchem.com)

Since this phase 1 study used the marketed presentation of Humalog (i.e., taking vials of Humalog and adding Biodel's excipients), Biodel is now working to replicate the BIOD-250 pharmacokinetic and tolerability profiles utilizing the active pharmaceutical ingredient, lispro. (closeconcerns.com)
the vials do not contain antiseptic excipients. (janusinfo.se)

The English edition (ISBN 7117069821) describes itself as a "compendium of almost all traditional Chinese medicines and most western medicines and preparations. (wikipedia.org)
With a positive and progressive track-record in the pharmaceutical industry, Clariant has a wide product portfolio of Excipients beneath the brands VitiPure® , Polyglykols , Lanogen® and Motusflex® supported by our high-quality standards to maximize the potential in medicines. (clariant.com)

Comparing FTIR and 1 H NMR spectra of GCV and physical mixtures of GCV and excipients, no significant deviation of characteristic peaks in infrared spectroscopy and 1 H NMR signals was observed. (ajbps.org)

Liquid preparations are usually sweetened with sucrose, which can be readily fermented by oral acidogenic bacteria. (bvsalud.org)

VitiPure P 188 is all rounder non-ionic polymer suitable for various pharmaceutical applications. (clariant.com)

Pharmaceutical companies in UAE ensure constant quality, consistent supply of citrate components as well as the value-added services you require. (yellowpages.ae)
Pharmaceutical Technology 1 presents the use of excipients, specific pharmaceutical manufacturing procedures and quality control methods for dosage forms. (cuni.cz)
It ensures and regulates the quality of pharmaceuticals in Europe. (lu.se)

The general preparation method is, to prepare an oil and aqueous phase separately and then mix, after mixing add fragrance or other ingredients, then homogenize and congeal. (pharmaeducation.net)

Biomedical and Life Sciences: American Association of Pharmaceutical Scientists, 11 (4). (gre.ac.uk)

The ability to co-process α-chitin with crystalline mannitol allows chitin to be used as a valuable industrial pharmaceutical excipient. (gre.ac.uk)

Citrate ingredients are used in a myriad of pharmaceutical applications including pH adjustment, stabilization, and flavor enhancements. (yellowpages.ae)
Identify active pharmaceutical ingredients and excipients with Raman spectroscopy. (anton-paar.com)
These usually unwanted effects can be problematic when, for example, excipient and active pharmaceutical ingredients separate or segregate. (anton-paar.com)

The aim of the present study is to illustrate compatibility testing of ganciclovir (GCV) with some common excipients that would be used to manufacture solid oral dosage forms. (ajbps.org)
The need for consistency in analytical method development intensifies the dependence of pharmaceutical product development and manufacture on robust analytical data. (ijpsonline.com)

Medicated cold cream is mainly used as a topical pharmaceutical dosage form for the treatment of skin. (pharmaeducation.net)
Uses of cold cream are less than vanishing cream (oil in water emulsion) as topical pharmaceutical dosage form. (pharmaeducation.net)

Silicone tubing can be manufactured through peroxide or platinum curing, with platinum-cured silicone tubing being the top choice in biopharmaceutical, pharmaceutical, and food and beverage industries for its high purity and superior physical properties. (ilcdover.com)
The effect of the ratio of the two components, percentage of lubricant and particle size, on the properties of the prepared co-processed excipient has been investigated. (gre.ac.uk)

Excipients" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)

Since adherence to the treatment regimen will be affected if the product is not acceptable to infants, young children and their mothers or caregivers, zinc preparations should be formulated as palatable and in such a way as to mask the strong bitter metallic aftertaste of zinc in order to enhance acceptability. (who.int)

The company's insulin portfolio also includes the ultra-rapid-acting BIOD-123 (recombinant human insulin (RHI) combined with Biodel's proprietary excipients) - enrollment in the phase 2 clinical trial (n=130) is progressing according to schedule and top-line data is still expected in 3Q13 (ClinicalTrials.gov Identifier: NCT01686620). (closeconcerns.com)
VitiPure CO 35 is a non-ionic solubiliser and emulsifying agent for the human and veterinary pharmaceutical industries. (clariant.com)
None of the excipients are of animal or human origin. (who.int)
The intelligent and human sensory evaluation results showed that the similarity values of HLG and its placebo about the CQAs at granule and solution status were all close to 1, which means that the two preparations have high similarities. (hindawi.com)

IG-004 (formerly known as TOCOSOL® paclitaxel) is a TPGS-based emulsion of paclitaxel, which was recently acquired from OncoGenex Pharmaceuticals, Inc. (OGXI). (biospace.com)

M/S Laboratories Pharmaceutiques Rodael, Fierne, France) and API-excipient compatibility studies. (who.int)
For lack of relevant research data, consider conducting excipient compatibility studies. (medicilon.com)

1 Clinical Pharmacy and Pharmaceutical Care Unit, Department of Pharmacy and Pharmaceutical Technology, and Physical Chemistry, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII 27-31, 08028, Barcelona, Spain. (nih.gov)

Organisms3

Chemicals and Drugs60

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes16

Disciplines and Occupations3

Technology, Industry, Agriculture11

Health Care5

Formulations7

Formulation10

APIs6

Impurities3

Tablets7

Phospholipids1

Drugs10

Substances4

Maize starch3

Stability5

Granulation3

Solubility1

Lactose3

Compression3

Polymers2

Parenteral1

Products17

Radiopharmaceutical3

Drug9

Gels1

Magnesium1

Characterization3

Powder1

Vials2

Medicines2

Infrared spectroscopy1

Liquid1

Various pharmaceutical1

Quality3

Aqueous1

Biomedical1

Crystalline1

Ingredients3

Manufacture2

Topical2

Properties2

MeSH1

Product1

Human4

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Compatibility2

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