• Research topics in molecular evolution include the characterization of novel hantaviruses harbored by shrews, moles and bats in different geographic locations and investigation of Burkholderia pseudomallei in humans, animal models, and in the environment. (hawaii.edu)
  • Rasmus Nielsen is certainly one of these researchers, and his work so far has merged many population genetic and phylogenetic aspects of biological research under the umbrella of molecular evolution. (springer.com)
  • Further chapters detail genetic variation of viruses and the molecular basis of interrelation at the population level and the molecular basis and evolution of this relationship. (cambridge.org)
  • The content and structure of a genome is the product of the molecular and population genetic forces which act upon that genome. (wikipedia.org)
  • Although nonneutral convergent evolution of morphological characters has been frequently pointed to as a source of potential bias in phylogenetic inference ( 4 - 6 ), nonneutral convergence at the molecular-genetic level is believed to be relatively rare and limited in scope. (pnas.org)
  • This session will highlight research that harnesses the power of experimental evolution, phylogenetic reconstructions, and standing genetic variation to gain insight into molecular systems. (grc.org)
  • The most common genetic change found in the evolution of typical Ph1 chromosome positive CML to blast crisis was an alteration of the p53 gene involving either a rearrangement, a deletion, or a point mutation in the coding sequence of the gene. (jci.org)
  • We often hear about new 'genome sequences,' commercial kits that can tell you about your ancestry (including pre-human) from your DNA or disease predispositions, debates about the truth of evolution, why animals behave the way they do, and how people found 'genetic evidence for natural selection. (coursera.org)
  • The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. (oup.com)
  • Dr. Robert Heinzen, head of the Coxiella Pathogenesis Section at the National Institute of Allergy and Infectious Disease, remarked, "Our results suggest that mobile genetic elements have played a major role in the evolution and function of the C. burnetii genome. (infectioncontroltoday.com)
  • This chapter reviews the recent (mostly) molecular data that provide new insights into the evolution, taxonomy, phylogenetic, and population genetic relationships of Leishmania but also the questions raised by this knowledge. (springer.com)
  • Additionally, explicit use of molecular evolutionary and phylogenetic analyses provide important insights in their own right, e.g., analysis of adaptive evolution in viruses providing clues of their interaction with host immune systems. (embo.org)
  • This book is one of the first solely devoted to the origins and evolution of viruses, and of the ways in which they interact with their cellular hosts and vectors. (cambridge.org)
  • The conference taught me an important lesson: Evolution of a biochemical process can teach us a great deal about how it operates - it can help determine which features are fundamental and which represent cellular or organismal specialization. (asbmb.org)
  • I have often neglected to consider evolution when trying to understand the molecular basis of a given cellular process. (asbmb.org)
  • The main problem with this idea is that, not only does no such creature exist, but eukaryotes also contain molecular similarities to both bacteria and archaea-prokaryotes that are found in completely separate domains of cellular life. (icr.org)
  • Another major problem is that many complex molecular and cellular features unique among eukaryotes are not found in any prokaryotes. (icr.org)
  • Clearly, the only scientific model that predicts this type of molecular and cellular complexity and innovation across all forms of life is one associated with special creation. (icr.org)
  • Viewing molecular and cellular processes within their evolutionary contexts can reveal key mechanistic information. (grc.org)
  • Many cellular features, such as molecular machines, require multiple interactive parts to function. (evolutionnews.org)
  • Molecular evolution of the synapsin gene family. (nih.gov)
  • In invertebrate synapsins, the most conserved domains are C and E. During the evolution of vertebrates, at least two gene duplication events are hypothesized to have given rise to the synapsin gene family. (nih.gov)
  • However, the nucleotide sequence of rpoB from one isolate examined suggests that interspecies gene transfer may also have played a role in the evolution of rifampicin-resistance in S. pneumoniae. (nih.gov)
  • Mutations are considered the driving force of evolution , where less favorable (or deleterious ) mutations are removed from the gene pool by natural selection , while more favorable (or beneficial ) ones tend to accumulate. (bionity.com)
  • The near‐neutrality concept may be extended to the evolution of such systems, where epigenetics and robustness are important for gene expression and many mutations are weakly selected. (els.net)
  • Khaitovich P, Enard W, Lachmann M and Pääbo S (2006) Evolution of primate gene expression. (els.net)
  • We were able to deduce that, long before the evolution of termites, one particular class of transposons led to the expansion of gene families probably involved in communication," added Dr Evelien Jongepier, also first author. (idw-online.de)
  • They found that - at the scale of random changes to gene sequence - the lice are winning the molecular evolutionary race. (medindia.net)
  • Human Gene Evolution. (researchandmarkets.com)
  • Presents the principles of human gene evolution in a concise and easy to understand fashion. (researchandmarkets.com)
  • Here we show that some members of the LOX gene family in the Arabidopsis genome are likely to be lost during evolution, leading to a smaller size than that in Populus, Vitis , and Carica . (frontiersin.org)
  • The researchers were able to correlate the progressive loss of enamel in the fossil record with a simultaneous molecular decay of a gene, called the enamelin gene, that is involved in enamel formation in mammals. (innovations-report.com)
  • In our research we clearly see the parallel evolution of enamel loss in the fossil record and the molecular decay of the enamelin gene into a pseudogene in representatives of four different orders of mammals that have lost enamel. (innovations-report.com)
  • Zou, Z., and J. Zhang (2017) Gene tree discordance does not explain away the temporal decline of convergence in mammalian protein sequence evolution. (umich.edu)
  • UCLA molecular biologist James A. Lake reports important new insights about prokaryotes and the evolution of life in the Aug. 20 advance online edition of the journal Nature . (nsf.gov)
  • In addition, it is theorized that certain chemical reactions may have taken place on early Earth, before true evolution began, and some of these reactions may have helped to form these informational molecules that enabled replication and mutation. (encyclopedia.com)
  • They are also learning that the enzymes that copy and maintain the DNA introduce changes in some parts of the genome and not others, creating hotspots of mutation that increase the efficiency of evolution. (ucla.edu)
  • Papers based on few taxa, single molecular markers, or that use codon-based methods to test for positive Darwinian selection, but in the absence of experimental evidence that allegedly selected amino acid changes cause an adaptive phenotypic effect, will not be accepted. (elsevier.com)
  • Irreducibly complex parts at the molecular level are actually cobbled together by simpler parts and put together as a whole. (hubpages.com)
  • Evolution works at the DNA level. (hubpages.com)
  • Fay JC (2011) Weighing the evidence for adaptation at the molecular level. (els.net)
  • Although many important discoveries have been made, the question of how memories are encoded and maintained at the molecular level remains. (nature.com)
  • This information will prove invaluable as we proceed to dissect, at a molecular level, events associated with Q fever pathogenesis. (infectioncontroltoday.com)
  • In recent years, sequencing technologies have made it possible to observe the outcomes and, in some cases, the process, of molecular evolution at a remarkable level detail. (mpg.de)
  • I need to be careful what I say here - one ticking off I got was from a biologist who was unhappy that I had over-stressed natural selection at the molecular level, which I freely confess was a slight failure of nerve - I have found that saying such things can induce apoplexy in folks who see the shadows of creationism everywhere. (blogspot.com)
  • She works in the project "Phylogeny, historic biogeography and niche evolution of the neotropical Marcgraviaceae - a model case of swift morphological diversification and speciation by flower-pollinator-interaction" (project leader: Dr. Stefan Dressler) with funding from DFG (Deutsche Forschungsgemeinschaft). (senckenberg.de)
  • These data demonstrate both the successes of previous theoretical work in describing the qualitative features of molecular evolution, and the quantitative limitations that suggest opportunities for future work. (mpg.de)