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  • Inhibitor
  • Development of 1-((1,4-trans)-4-Aryloxycyclohexyl)-3-arylurea Activators of Heme-Regulated Inhibitor as Selective Activators of the Eukaryotic Initiation Factor 2 Alpha (eIF2a) Phosphorylation Arm of the Integrated Endoplasmic Reticulum Stress Response. (harvard.edu)
  • Molecular
  • The discovery of genetic factors that predispose individuals to rapid progression to AIDS should also reveal new insights into the molecular etiology of the pathology. (genes2cognition.org)
  • regulatory
  • Second, the mRNA transcript is spliced into different variants based on an assortment of regulatory signals and factors controlling the gene's expression. (icr.org)
  • receptor
  • Data indicate that TNF receptor associated factor 4 (TRAF4) recruited the E3-ligase SMURF2, to degrade the IL-25R-inhibitory molecule DAZ associated protein 2 (DAZAP2). (antibodies-online.com)
  • Certain hydrophobic molecules that bind to the capsid in competition with pocket factor exert a powerful antiviral action by interfering with receptor binding and/or uncoating. (ictvonline.org)
  • site
  • Following release of eEF1A-GDP, the aminoacyl-tRNA is accommodated into the A site, and the eEF1A-GDP is recycled to eEF1A-GTP by the exchange factor eEF1B. (sdbonline.org)
  • The binding site for the pocket factor lies beneath the floor of this canyon within the 1D β-barrel. (ictvonline.org)
  • release
  • Binding of eEF2-GTP promotes translocation of the tRNAs into the canonical P and E sites, and is followed by release of eEF2-GDP, which unlike eEF1A does not require an exchange factor. (sdbonline.org)