• Within the medical field of respiratory therapy, Open lung ventilation is a strategy that is utilized by several modes of mechanical ventilation to combine low tidal volume and applied PEEP to maximize recruitment of alveoli. (wikipedia.org)
  • Barotrauma is a well-recognized complication of mechanical ventilation . (medscape.com)
  • [ 1 ] Although most frequently encountered in patients with the acute respiratory distress syndrome (ARDS), it can occur in any patient receiving mechanical ventilation. (medscape.com)
  • In clinical medicine, barotrauma is used to describe the manifestations of extra-alveolar air during mechanical ventilation. (medscape.com)
  • Although nonmechanically ventilated patients may have barotrauma, most cases occur in patients receiving mechanical ventilation. (medscape.com)
  • Barotrauma was once the most frequent and easily recognized complication of mechanical ventilation. (medscape.com)
  • We randomly assigned 549 patients with acute lung injury and ARDS to receive mechanical ventilation with either lower or higher PEEP levels. (criticalcarepractitioner.co.uk)
  • However, it did improve lung function and reduced the duration of mechanical ventilation and the duration of organ failure. (criticalcarepractitioner.co.uk)
  • Serpo Neto et al performed a meta-analysis of 20 prior studies that tested higher vs. lower tidal volumes in patients requiring mechanical ventilation who did not have ARDS or acute lung injury at the time of intubation. (pulmccm.org)
  • The average duration of per-protocol mechanical ventilation was short , only 6.9 hours in the lung protective group and 6.56 hours in the conservative group. (pulmccm.org)
  • This is the most dreaded manifestation of barotrauma, and continued accumulation of air during mechanical ventilation can progress to a tension pneumothorax, sometimes with catastrophic consequences. (medscape.com)
  • Historically, mechanical ventilation was initiated with a tidal volume based on a patient's actual body weight, which was believed to reflect metabolic need. (biomedcentral.com)
  • To the Editor The inherent physiological rationale for lowering tidal volume during mechanical ventilation is to decrease strain on the lung tissue to avoid ventilator-induced lung injury. (annarborbonsaisociety.org)
  • Importance In patients who undergo mechanical ventilation during surgery, the ideal tidal volume is unclear. (annarborbonsaisociety.org)
  • This study was designed to investigate the influences of clinical variables and mechanical ventilation settings on the outcomes for severe ARDS patients receiving ECMO. (springeropen.com)
  • There was no large multicenter prospective randomized controlled trial to address the optimal mechanical ventilation settings during ECMO in severe ARDS patients. (springeropen.com)
  • Mechanical ventilation is an essential therapy to support critically ill respiratory failure patients. (biomedcentral.com)
  • In intensive care, mechanical ventilation (MV) is the primary support for patients with respiratory failure or acute respiratory distress syndrome (ARDS) despite decades of research [ 1 ]. (biomedcentral.com)
  • Borges et al report on their 10-y experience of home mechanical ventilation in children. (rcjournal.com)
  • Measurements in non obese patients, after docking and insufflation of the abdomen, found that the fractional pressure presented to the lungs by mechanical ventilation is reduced (48% from 63% immediately after intubation). (blogspot.com)
  • Unfortunately, the results were scattered with many studies unable to clearly show definite and meaningful benefits with "lung protective ventilation" strategies during routine clinical mechanical ventilation. (blogspot.com)
  • Evolution of Diaphragm Thickness during Mechanical Ventilation. (atsjournals.org)
  • Diaphragm atrophy and dysfunction have been reported in humans during mechanical ventilation, but the prevalence, causes, and functional impact of changes in diaphragm thickness during routine mechanical ventilation for critically ill patients are unknown. (atsjournals.org)
  • To describe the evolution of diaphragm thickness over time during mechanical ventilation, its impact on diaphragm function, and the influence of inspiratory effort on this phenomenon. (atsjournals.org)
  • Changes in diaphragm thickness are common during mechanical ventilation and may be associated with diaphragmatic weakness. (atsjournals.org)
  • Titrating ventilatory support to maintain normal levels of inspiratory effort may prevent changes in diaphragm configuration associated with mechanical ventilation. (atsjournals.org)
  • Beyond sepsis-induced inflammation, a mechanical ventilation regimen can also propagate ventilator-related injury that may precipitate ARDS. (ceufast.com)
  • Inclusion criteria were age 18 years or older, oral endotracheal intubation, and conventional mechanical ventilation (MV). Patients with obesity, chronic respiratory disease, laryngeal disease or anomaly, and difficult intubation (two or more trials), were excluded from the study. (biomedcentral.com)
  • BPD is a chronic lung disease that most commonly occurs in premature infants who have needed mechanical ventilation and oxygen therapy for infant RDS. (patient.info)
  • The need for nasal CPAP or mechanical ventilation further supports the definition of severe BPD. (patient.info)
  • The Aura V system provides comprehensive mechanical ventilation options for clinicians. (ipmchirana.com)
  • Because intubation and mechanical ventilation alter first-line patient defenses, they greatly increase the risk for nosocomial bacterial pneumonia. (cdc.gov)
  • There are 3 main ways auto-PEEP occurs: 1) High minute ventilation - high respiratory rates or high tidal volumes Similar to pulmonary function tests, these will include tidal breathing (the normal breathing volume), respiratory rate, and vital capacity (breathing volume during a deep breath). (annarborbonsaisociety.org)
  • During the anesthetic, his minute ventilation was unusually large for this 71 kg male. (blogspot.com)
  • Multiple ventilation manipulations were provided in an atttempt to improve ventilation, decrease airway pressures including driving pressure as well as minute ventilation. (blogspot.com)
  • A total of 43 respirators were tested for work of breathing at minute ventilation rates of 10, 35, 65, 105, and 135 liters per minute. (cdc.gov)
  • The National Institute for Occupational Safety and Health's breathing resistance is close to work of breathing's minute ventilation of 35 liters per minute, which represents the common walking/working pace in most workplaces. (cdc.gov)
  • During sleep, there is a decrease in minute ventilation. (atsjournals.org)
  • p is the minute ventilation rate of the exposed sus- mail in the business office of a media company. (cdc.gov)
  • The low tidal volume aims to minimize alveolar overdistention and the PEEP minimizes cyclic atelectasis. (wikipedia.org)
  • There has been controversy regarding the optimal approach for lung-protective ventilation, but consistent benefit has been noted with low tidal volume and no increased risk with varying levels of positive end-expiratory pressure (PEEP). (medscape.com)
  • The model predicted that for variables applicable to an infant with respiratory distress syndrome, the selection of positive end-expiratory pressure (PEEP) becomes critical because the penalties in pressure cost are amplified for both high and low values of PEEP. (nih.gov)
  • This analysis illustrates the importance of using high-frequency ventilation in infant respiratory distress syndrome and of optimizing the amount of PEEP. (nih.gov)
  • When the lungs are in a derecruited state, the combinations of frequency, PEEP, and tidal volume that yield adequate ventilation with safe distention of recruited alveoli are severely limited. (nih.gov)
  • and an end-inspiratory plateau-pressure limit of 30 cm of water, clinical outcomes are similar whether lower or higher PEEP levels are used. (criticalcarepractitioner.co.uk)
  • In patients with moderate to severe ARDS, a strategy with lung recruitment and titrated PEEP compared with low PEEP increased 28-day all-cause mortality . (criticalcarepractitioner.co.uk)
  • In patients with moderate - severe ARDS, an open lung strategy that included maximal RMs and PEEP titration compared to conventional lung-protective ventilation did not improve VFDs or mortality . (criticalcarepractitioner.co.uk)
  • The tidal volumes utilized were 6 ml/kg in the low tidal volume group and 12 ml/kg in the conventional tidal volume group and the study utilized standardized PEEP/FiO2 tables. (pulmccm.org)
  • Should they err on the small side by emulating the ARDSnet protocol, or should they avoid the dangers of higher PEEP and the potential for atelectasis by using higher tidal volumes? (pulmccm.org)
  • Key elements of a lung-protective strategy are the application of positive end-expiratory pressure (PEEP), limitation of plateau pressure, and a minimal tidal volume scaled to a 'predicted', rather than actual, body weight. (biomedcentral.com)
  • However, the lung available for ventilation is significantly reduced … Other possible sequelae of auto-PEEP are barotrauma, ventilator-induced lung injury, and V/Q mismatch. (annarborbonsaisociety.org)
  • The benefits of higher or lower tidal volume, PEEP, and other settings are highly debated and no consensus has been reached. (biomedcentral.com)
  • In general, patients were divided into groups of high vs. low Vt (i.e. 10-12 ml/kg vs. 6-8 ml/kg) and groups of standard PEEP or no PEEP. (blogspot.com)
  • Integrating established knowledge of influenza A virus-induced ARDS pathophysiology, we discuss how shared clinical findings frame influenza as only an approximate model for COVID-19. (ersjournals.com)
  • After combing key data from the different studies, the authors then measured the following end-points in patients ventilated with higher vs. lower tidal volumes: 1) development of ARDS 2) mortality 3) pulmonary infection 4) atelectasis. (pulmccm.org)
  • The lung-protective ventilation bundle has been shown to reduce mortality in adult acute respiratory distress syndrome (ARDS). (biomedcentral.com)
  • LARGE tidal volumes (V T) contribute to and worsen the acute respiratory distress syndrome (ARDS) in intensive care unit (ICU) patients after hours or days of ventilation. (annarborbonsaisociety.org)
  • A lung-protective ventilation strategy with lower tidal volume remains the cornerstone of treatment for ARDS and is associated with improved survival [ 2 ]. (springeropen.com)
  • In the absence of these predisposing conditions, the probability that the other hits would result in ARDS is lower. (springeropen.com)
  • Recruitability of the lung estimated by the pressure volume curve hysteresis in ARDS patients. (hamilton-medical.com)
  • Dozens of studies showed reduced mortality in ICU patients who were ventilated due to ARDS when they were treated with low plateau pressure (Pplat) which often required reducing tidal volumes (Vt) to around 6 to 8 mL/kg and permissive hypercapnia. (blogspot.com)
  • Prone positioning (PP) improves oxygenation and respiratory mechanics and is associated with lower mortality in patients with moderate to severe acute respiratory distress syndrome (ARDS). (biomedcentral.com)
  • This will be a great challenge for airway management, especially in thoracic surgery requiring one-lung ventilation. (bvsalud.org)
  • Solutions to these models were combined to assess the total pressure cost of high-frequency ventilation as a function of the ventilatory settings and the pathophysiologic variables of the patient. (nih.gov)
  • In addition, maintenance of the appropriate level of sedation in the Intensive Care Unit (ICU) during ventilatory support and weaning is subjective and may result in prolonged ventilation secondary to excessive sedation. (ispub.com)
  • This article discussed a new paradigm emerging in ventilatory medicine to improve ventilation while reducing the incidence of ventilator induced lung injury (VILI). (blogspot.com)
  • In fact, bigger (meaning high tidal volumes) does not even reduce the risk of developing atelectasis, which may be the last physiologic rationale for selecting higher tidal volumes. (pulmccm.org)
  • The authors hypothesised that bilevel ventilation might be easier to initiate and superior to CPAP at correcting the sleep-related abnormality of breathing in patients with CCF. (ersjournals.com)
  • Two 14-day cycles of CPAP (0.85 kPa (8.5 mbar)) or bilevel ventilation (0.85/0.3 kPa (8.5/3 mbar)) in random order, were compared in a crossover study. (ersjournals.com)
  • The pretreatment apnoea/hypopnoea index of 26.7±10.7 was significantly reduced by CPAP and bilevel ventilation to 7.7±5.6 and 6.5±6.6, respectively. (ersjournals.com)
  • Significant and equal improvements with CPAP and bilevel ventilation were found for sleep quality, daytime fatigue, circulation time and New York Heart Association class. (ersjournals.com)
  • Continuous positive airway pressure (CPAP) and time-controlled bilevel ventilation (bilevel spontaneous/timed) are both used as symptomatic approaches to treat sleep disordered breathing, correct hypoxaemia, reduce arousals, decrease sympathetic tone, and improve sleep quality 11 , 12 . (ersjournals.com)
  • CPAP requires a spontaneously breathing patient and will be ineffective for central apnoeas, whereas timed bilevel ventilation is able to ventilate a patient even in the absence of spontaneous respiratory effort. (ersjournals.com)
  • Bilevel ventilation has been suggested as an alternative, but little is known about the efficacy or tolerance of bilevel ventilation in these patients and, in particular, it has not been compared to CPAP. (ersjournals.com)
  • The authors hypothesised that bilevel ventilation might be more effective than CPAP in terms of reducing pathological respiratory events and be better tolerated by patients. (ersjournals.com)
  • The most common clinical scenario is of a 23- to 26-weeks of gestation baby who over a period of 4-10 weeks progresses from needing ventilation to CPAP through to requiring supplemental oxygen. (patient.info)
  • Most babies have initial RDS and require respiratory support in the form of ventilation or CPAP. (patient.info)
  • This involvement can lead to maldistribution of mechanically delivered tidal volume, with some alveoli subjected to more distention than others. (medscape.com)
  • High alveolar ventilation brings more O2 into the alveoli, increasing O2 , and rapidly eliminating CO2 from the lungs (for chemical abbreviations see Table 2). (bartleby.com)
  • Concern that lower tidal volumes may cause respiratory acidosis and decrease arterial oxygenation. (criticalcarepractitioner.co.uk)
  • Activation of the sympathetic nervous system coincides with low levels of blood and tissue oxygenation. (ersjournals.com)
  • OBJECTIVES: In this trial, we aimed to compare anesthetic effectiveness of single lumen tube (SLT) for tracheal intubation with high-frequency positive pressure ventilation (HFPPV) versus classic double lumen tube (DLT) for tracheal intubation in endoscopic thoracic sympathetic blockade surgery. (bvsalud.org)
  • Ventilation using a bag and mask should be minimised in favour of endotracheal intubation if prolonged resuscitation is required. (vic.gov.au)
  • To restate, higher chest wall stiffness results in a lower fraction of airway pressure distributed to the lungs during the Trendelenburg position and docked robot condition than after intubation. (blogspot.com)
  • Immediate availability of resuscitative drugs and age- and size-appropriate equipment for bag/valve/mask ventilation and intubation, and personnel trained in their use and skilled in airway management should be assured (see WARNINGS). (nih.gov)
  • Once tracheal intubation with a single-lumen ETT is confirmed, a BB may be used to establish OLV, or a tube exchanger may be used to replace the ETT with a DLT. (medscape.com)
  • In COPD, long-term oxygen therapy improves survival in severe daytime hypoxaemia and noninvasive ventilation reduces the need for intubation after acute hypercapnic respiratory failure and improves survival in stable in chronic hypercapnia. (ersjournals.com)
  • During the years, substantial focus has been placed on the role of the lung, ventilation and pulmonary gas exchange limitations on exercise impairment at altitude. (bmj.com)
  • However, for this review, we will focus primarily on the role that pulmonary gas exchange and specifically arterial oxyhaemoglobin saturation (SaO 2 , or SpO 2 when measured by oximetry) maintenance plays in predicting the decline in exercise performance at mild, moderate and the lower range of high altitude. (bmj.com)
  • Low tidal volume is an effective ventilation strategy, but clinicians have been somewhat slow to adopt this approach. (medscape.com)
  • The overall goal is a review of ventilation that is accessible to both clinicians and engineers, to bridge the divide between the two fields and enable collaboration to improve patient care and outcomes. (biomedcentral.com)
  • Figure 1- Effect of lung mechanics and inspiratory time on tidal volume (V T) delivery during high-frequency oscillatory ventilation.a) Maximum potential V T is determined by lung compliance (C L) and inspiratory time (t I), while the rate of V T delivery is determined by lung mechanics. (annarborbonsaisociety.org)
  • Post arrest respiratory compliance remained poor necessitating an increase in the pressure limit to allow for PIP persistently greater than 40 cm H20, despite reduction in tidal volume to 4 milliliter per kilogram, muscle relaxation, and prolongation of inspiratory time. (apsf.org)
  • Echocardiography is considered the most reliable noninvasive test to establish the diagnosis, assess cardiac function, and exclude associated structural heart disease. (medscape.com)
  • With increasing evidence to support its use, the overall tidal volume used in mechanically ventilated patients had decreased over time, and current practice involves tidal volumes that are lower than those used in the past. (medscape.com)
  • In this meta-analysis of a heterogeneous group of mechanically ventilated patients, patients who received lower tidal volumes showed a statistically significant decrease in all of the key outcomes measured in this trial. (pulmccm.org)
  • Sections on the prevention of bacterial pneumonia in mechanically ventilated and/or critically ill patients, care of respiratory-therapy devices, prevention of cross-contamination, and prevention of viral lower respiratory tract infections (e.g., respiratory syncytial virus {RSV} and influenza infections) have been expanded and updated. (cdc.gov)
  • A low Apgar score is a clinical finding and not a diagnosis. (msdmanuals.com)
  • Articles published in WJR are high-quality, basic and clinical, influential research articles by established academic authors as well as new researchers. (referencecitationanalysis.com)
  • This review presents the significant clinical aspects and variables of ventilation management, the potential risks associated with suboptimal ventilation management, and a review of the major recent attempts to improve ventilation in the context of these variables. (biomedcentral.com)
  • After the benefits of lower tidal volumes and permissive hypercapnea were realized, a large number of studies attempting to translate these results into clinical anesthesia were published. (blogspot.com)
  • Background Prone positioning (PP) is an established and commonly used lung recruitment method for intubated patients with severe acute respiratory distress syndrome, with potential benefits in clinical outcome. (researchsquare.com)
  • Lung-protective ventilation with permissive hypercarbia and hypoxia is an important strategy in the critically ill baby with CDH. (vic.gov.au)
  • Introduction: Point-of-care ultrasound (POCUS) has an established role in the management of the critically ill. (bvsalud.org)
  • and b) the convective flow cost necessary to achieve a unit of alveolar ventilation. (nih.gov)
  • Simple solutions for each of these cost functions were formulated using established models of gas exchange and lung mechanics, including the effects of lung inflation tidal volume and respiratory frequency in alveolar ventilation, nonlinear lung tissue compliance, and alveolar recruitment and derecruitment. (nih.gov)
  • After ECMO initiation, tidal volume, peak inspiratory pressure and dynamic driving pressure were decreased, while positive end-expiratory pressure levels were relative maintained. (springeropen.com)
  • At comparable VT, PAV had slightly lower peak inspiratory flow and higher driving pressure compared with PSV. (medscimonit.com)
  • Lung-protective ventilation has also been shown to improve outcomes in patients ventilated in the operating room and in the intensive care unit (ICU) [ 4 , 5 ]. (biomedcentral.com)
  • This has evolved over the years and there are now several studies indicating that the improvement in outcomes may be related more to reducing the driving pressure (Pdrive) rather than a purely low Vt permissive hypercapnea strategy. (blogspot.com)
  • Recently an article in European Journal of Anaesthesiology by Itagaki et al(1) with a cross over design showed an increase in tidal volume when the patients were ventilated in a head rotated position compared to neutral position with the same airway pressure. (resus.me)
  • Forced expiratory volume in one second (FEV1): Forced expiratory volume in one second measures the total amount of air that can be forcibly exhaled in the first second of the FVC test.Healthy people generally expel around 75% … Objective To determine whether low-tidal-volume ventilation compared with conventional ventilation during major surgery decreases postoperative pulmonary complications. (annarborbonsaisociety.org)
  • This is an important distinction because one of the few criticisms of the multicenter RCT conducted by the ARDSnet group was that the conventional tidal volumes were higher than usual practice. (pulmccm.org)
  • Their conclusion was as follows: Head rotation of 45° in anaesthetised apnoeic adults significantly increases the efficiency of mask ventilation compared with the neutral head position. (resus.me)
  • Head rotation is an effective alternative to improve mask ventilation if airway obstruction is encountered. (resus.me)
  • 1. Itagaki T, Oto J, Burns SM, Jiang Y, Kacmarek RM, Mountjoy JR. The effect of head rotation on efficiency of face mask ventilation in anaesthetised apnoeic adults. (resus.me)
  • however, during heavy exercise, many athletes demonstrate limitations to expiratory flow and are unable to increase ventilation in hypoxia. (bmj.com)
  • This will then increase ventilation but in several minutes. (bartleby.com)
  • Chemoreceptors in the arterial blood vessels are stimulated to signal the brain to increase ventilation. (bartleby.com)
  • In particular, the need for ventilation strategies which consider, and directly account for, the significant differences in patient condition, disease etiology, and progression within patients is demonstrated with the subsequent requirement for optimal ventilation strategies to titrate for patient- and time-specific conditions. (biomedcentral.com)
  • It has also been postulated that survival benefits of prone ventilation are independent of improvement in gas exchange and that it results from the ability of PP to reduce ventilator induced lung injury (VILI). (biomedcentral.com)
  • Whereas low-tidal-volume ventilation has been strongly advocated, plateau pressure may be a more useful parameter to monitor and a better reflection of barotrauma risk in these patients. (medscape.com)
  • With volume ventilators, this is best accomplished with low tidal volumes. (medscape.com)
  • IPM Chirana was formed as a strategic international partnership to rapidly accelerate global production of one of the most technologically advanced critical care ventilation systems in the world, the Aura V Ventilator, to address the shortage of critical care ventilators due to COVID-19. (ipmchirana.com)
  • CSR is characterised by periodic changes of tidal volume, resulting in 30-60-s cycles of hyperventilation, alternating with hypoventilation or apnoea in a crescendo decrescendo pattern. (ersjournals.com)
  • Hypoventilation after hyperventilation has a lower arterial pCO2, pO2 and Hb-O2 saturation than hypoventilation but longer in the duration of breath holding. (bartleby.com)
  • Pre study- Larger tidal volumes possibly cause greater detrimental effects such as disruption of pulmonary epithelium, lung inflammation, atelectasis, hypoxemia and the release of inflammatory mediators. (criticalcarepractitioner.co.uk)
  • Analysis from 1,019 patients undergoing one-lung ventilation indicated that low tidal volume in the presence of low positive end-expiratory pressure is associated with increased pulmonary complications. (annarborbonsaisociety.org)
  • The patient was ventilated using an Aisys CS² Anesthesia Delivery System (GE Healthcare, Chicago, IL) with volume control mode settings of 450 milliliter of tidal volume, positive end expiratory pressure of 5 centimeters of water (cm H2O), respiratory rate of 12, and an inspiratory to expiratory ratio of 1:2 with pressure limit set to 40 cm H2O. (apsf.org)
  • There are multiple possible causes of low (0 to 3) Apgar scores, including severe, chronic problems that have a poor prognosis and acute problems that can be quickly resolved and have a good prognosis. (msdmanuals.com)
  • To further investigate the tidal volume (VT) response to exercise in severe COPD, nine patients were … In COPD individuals, there is a resetting of the respiratory system's relaxation volume to a higher level than in the healthy individuals. (annarborbonsaisociety.org)
  • We read with extreme interest the recently published work by O'Donnell and colleagues (May 2010).1 Comparing lung volumes obtained using different techniques in a sample of patients with severe airflow limitation, the authors conclude that plethysmography systematically overestimates lung volumes with regard to gas dilution and thoracic imaging techniques. (annarborbonsaisociety.org)
  • The total lung capacity (TLC) is the volume of gas that is contained in the lungs at the end of maximal inspiration. (annarborbonsaisociety.org)
  • Inspiratory reserve volume is … Respiratory volumes are the amount of air inhaled, exhaled and stored within the lungs at any given time. (annarborbonsaisociety.org)
  • They evaluated adherence to therapy in a year-long study and found that adherence in adolescents (13-19 y) was significantly lower than younger age groups. (rcjournal.com)
  • After PP, patients had significantly higher PaO 2 /FiO 2 ratio, lower PaCO 2 and reduced ventilator driving pressure, and no major complications were reported. (biomedcentral.com)
  • 1,9-13 Many surgical patients undergo short-term ventilation with large V T (>10 ml/kg predicted body … There are a number of different measurements and terms which are often used to describe this including tidal volume, inspiratory reserve volume, residual volume, vital … Lung volumes and exercise. (annarborbonsaisociety.org)
  • Endotracheal tubes with high residual volume, low-pressure cuff, with an inner diameter of 7.5 mm for female and 8.0 mm for male, were used. (biomedcentral.com)
  • They found no differences in the degree of oxygen desaturation or ventilation as measured by expired carbon dioxide. (rcjournal.com)
  • An increase of H+ cannot influence the medullary receptors, but carbon dioxide in the arterial blood can cross the blood-brain barrier and lower the pH of cerebrospinal fluid and brain interstitial fluid (Fox 557). (bartleby.com)
  • It is well established that for an individual athlete training or competing at altitude maximal oxygen uptake (VO 2 max) will be impaired. (bmj.com)
  • Objective To determine the ability of lung ultrasound (LUS) of the dependent region to detect real-time changes in lung volume, identify opening and closing pressures of the lung, and detect pulmonary hysteresis. (bmj.com)
  • Conclusion LUS was able to detect large changes in total and regional lung volume in real time and correctly identified opening and closing pressures but lacked the precision to detect small changes in lung volume. (bmj.com)