• Current standard therapies for toxoplasmic encephalitis often cause severe adverse events. (cdc.gov)
  • Sincerely, Atrte, Anthony S. Fauci, Director National Institute of Allergy and Infectious Diseases Enclosures NIAID RESPONDS TO ACT UP ALLEGATIONS AND DEMANDS The AIDS Clinical Trials Group (ACTG) of the National Institute of Allergy and Infectious Diseases (NIAID) was established to evaluate promising therapies for use against the human immunodeficiency virus (HIV), the cause of AIDS, and the opportunistic infections (OIs) and cancers that characterize AIDS. (nih.gov)
  • Trimethoprim/sulfamethoxazole (10 mg/kg/d trimethoprim) was first initiated because of limited availability of pyrimethamine plus sulfadiazine at the time, but acute liver toxicity developed on treatment day 6 (increases in levels of aminotransferase/alanine aminotransferase from 24/20 IU/L to 127/145 IU/L[(reference 10-42 IU/L]). Pyrimethamine plus sulfadiazine was started on treatment day 7. (cdc.gov)