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  • distal
  • Clinical symptoms were assessed using Eckardt score and manometry data were analyzed using resting and relaxation pressure (4sIRP) of lower esophageal sphincter (LES) and the distal contractile integral (DCI), which was calculated for 10 s from the start of deglutition between the upper margin of the LES and lower margin of upper esophageal contraction. (ovid.com)
  • With the patient supine, the tube was withdrawn uptil the distal tip was at the level of the lower sphincter, as detected by the pneumographic recording which showed respiratory reverse. (docme.ru)
  • mucosa
  • A whitish, well-defined mucosal patch or plaque caused by epidermal thickening or hyperkeratosis, commonly seen in the vermillion border of the lower lip, buccal mucosa, hard and soft palates. (brainscape.com)
  • acid
  • In LES circular muscle a low molecular weight pancreatic-like phospholipase A 2 ( group I PLA 2 ) causes production of arachidonic acid, which is metabolized to prostaglandins and thromboxanes. (nature.com)
  • smooth
  • Lower esophageal sphincter ( LES ) circular smooth muscle utilizes two distinct intracellular pathways: (1) a protein kinase C ( PKC )-dependent pathway activated by low doses of agonists or during maintenance of spontaneous tone, and (2) a Ca 2+ -calmodulin-myosin light chain kinase ( MLCK )-dependent pathway activated in response to maximally effective doses of agonists during the initial phase of contraction. (nature.com)
  • significantly
  • When comparing prognostic factors between successful and unsuccessful treatment groups, the mean value for 4sIRP in the unsuccessful treatment group was significantly lower than that in the successful treatment group (P (ovid.com)
  • digestive
  • The lower opening of the digestive tract through which feces (bowel movements) are discharged. (gi.org)