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  • risk
  • Colonization with strains positive for the CagA protein were associated with 59% reduced risk of esophageal adenocarcinoma (OR 0.41, 95% CI 0.28 to 0.62), reported Farin Kamangar, M.D., Ph.D., of the National Cancer Institute here, and Farhad Islami, Ph.D., of the University of Tehran in Iran and King's College London. (medpagetoday.com)
  • Another possibility is that it decreases production of the appetite stimulating hormone ghrelin, which could lead to lower rates of obesity -- an important risk factor for esophageal adenocarcinoma, according to the researchers. (medpagetoday.com)
  • All 13 studies that evaluated esophageal adenocarcinoma in a total of 840 cases and 2,890 controls found reduced risk with H. pylori colonization. (medpagetoday.com)
  • We hypothesised that male predominance in oesophageal adenocarcinoma is due atleast to established risk factors having a more harmful effect on men than women and that protective factors have a stronger preventive effect on women than men. (pubmedcentralcanada.ca)
  • Objectives To investigate cancer risk, particularly oesophageal cancer, among male upstream petroleum workers offshore potentially exposed to various carcinogenic agents. (bmj.com)
  • Results Male offshore workers had excess risk of oesophageal cancer (RR 2.6, 95% CI 1.4 to 4.8) compared with the reference population. (bmj.com)
  • Only the adenocarcinoma type had a significantly increased risk (RR 2.7, 95% CI 1.0 to 7.0), mainly because of an increased risk among upstream operators (RR 4.3, 95% CI 1.3 to 14.5). (bmj.com)
  • Conclusion We found a fourfold excess risk of oesophageal adenocarcinoma among male workers assumed to have had the most extensive contact with crude oil. (bmj.com)
  • however, this metaplasia confers an increased risk of adenocarcinoma. (wikipedia.org)
  • tumor
  • Organisation (WHO), a true signet-ring cell carcinoma (SRCca) is defined as an adenocarcinoma in which the predominant component (more than 50% of the tumor) consists of isolated or small groups of SRC in the stroma. (knowcancer.com)
  • If the tumor contains less than 50% of those cells, it is generally considered as an adenocarcinoma (ADC). (knowcancer.com)
  • Prominent symptoms usually do not appear until the cancer has infiltrated over 60% of the circumference of the esophageal tube, by which time the tumor is already in an advanced stage. (wikipedia.org)
  • findings
  • On the basis of these findings, about half of the four-fold increased occurrence of esophageal adenocarcinoma in Western countries could be the result of the "prominent decline of H. pylori colonization in the past few decades," the investigators wrote. (medpagetoday.com)
  • 2001
  • MacDonald JS, Smalley SR, Benedetti J et al (2001) Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastresophageal junction. (springer.com)
  • results
  • Due to the small number of cases, and a lack of detailed data on occupational exposure and lifestyle factors associated with oesophageal adenocarcinoma, the results must be interpreted with caution. (bmj.com)