Escherichia iron sulfur proteins. Medical search. Frequent questions

Iron-sulfur clusters are prosthetic groups composed of sulfur and iron that are found in respiratory chain complexes and numerous enzymes. (nih.gov)
Iron-sulfur clusters are synthesized in a multistep process that utilizes cysteine desulfurases, scaffold proteins, chaperones, and iron donors. (nih.gov)
Assembly of iron-sulfur clusters occurs in the mitochondrial matrix of mammalian cells, but cytosolic isoforms of three major mammalian iron-sulfur cluster (ISC) assembly components have been found, raising the possibility that de novo iron-sulfur cluster biogenesis also occurs in cytosol. (nih.gov)
Iron-sulfur (Fe-S) clusters are essential protein cofactors involved in various cellular processes. (alliedacademies.org)
The stability and transfer of Fe-S clusters mediated by proteins like NAF-1 regulate cellular resistance to oxidative stress. (alliedacademies.org)
Iron-Sulfur (Fe-S) clusters are ancient, versatile protein cofactors that are critical for various cellular processes including electron transfer, regulation of gene expression, and metabolism. (alliedacademies.org)
Schematic image of the two most common types of iron-sulfur clusters surrounded by cysteine ligands. (alliedacademies.org)
For some basic information about iron-sulfur clusters, their chemical properties, and coordination with the polypeptide chain, readers are referred to references of figure (1). (alliedacademies.org)
Proteins from the ISC operon of E. coli constitute the machinery used for the synthesis of iron-sulfur clusters and their delivery to recipient apo-proteins. (wisconsin.edu)
The flavin together with the iron-sulfur clusters function to mediate electron transfer from the dicarboxylate binding site on the Fp subunit to the membrane-anchor domain where quinone is reduced to quinol. (lu.se)
20. His-87 ligand in mitoNEET is crucial for the transfer of iron sulfur clusters from mitochondria to cytosolic aconitase. (nih.gov)
Fe-S clusters are present in more than 300 different types of enzymes or proteins and play crucial roles in fundamental life processes such as respiration, photosynthesis and nitrogen fixation. (uga.edu)
The coarse-grain iron content of exponentially growing cells consisted of iron-sulfur clusters, variable amounts of nonheme high-spin Fe II species, and an unassigned residual quadrupole doublet. (sc.edu)
In 2018 Nick was the recipient of the RSC's Joseph Chatt Award , in recognition of his contributions to the understanding of molecular mechanisms of bacterial gene regulation by environmental levels of oxygen, nitric oxide and iron employing iron-sulfur clusters. (uea.ac.uk)
Damage to FeS clusters can only be repaired by systems, such as iron-sulfur cluster or sulfur mobilization, requiring both iron and sulfur in the form of cysteine. (medscape.com)
The R. sphaeroides napF gene product is a 16.4 kDa protein with four cysteine clusters that probably bind four [4Fe-4S] centres. (bvsalud.org)

It is unexpected that B. subtilis SQR without covalently bound FAD is not assembled in the E. coli membrane provided that all other aspects of assembly, including iron-sulfur cluster biogenesis, are functional in the heterologous system. (lu.se)
1. Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis. (nih.gov)
2. Metabolic regulation of citrate and iron by aconitases: role of iron-sulfur cluster biogenesis. (nih.gov)
5. A role for IOP1 in mammalian cytosolic iron-sulfur protein biogenesis. (nih.gov)
11. Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation. (nih.gov)
13. Mitochondrial iron-sulfur protein biogenesis and human disease. (nih.gov)
17. Human ISCA1 interacts with IOP1/NARFL and functions in both cytosolic and mitochondrial iron-sulfur protein biogenesis. (nih.gov)
Legacy data from over 500 publications and three databases were reviewed, and many pathways were considered, including stable RNA maturation and modification, protein complex formation, and iron-sulfur cluster biogenesis. (ucsd.edu)
Their movement is essential for the endurance of the cell, for the biogenesis of mitochondria, and for the inventory of cytoplasm proteins with mitochondrial gathered iron-sulfur groups. (oakleysunglassess.com)
Moreover, a molecular-level understanding of iron-sulfur cluster biogenesis is crucial for understanding a variety of human diseases involving anemias, myopathies and ataxias that arise from defects in Fe-S cluster biogenesis proteins. (uga.edu)
93 Alkaloid work 93 Kallikrein-kallidinogen-kallidin system 93 Informal collaborative research 93 Laboratory of clinical biochemistry 94 Am ine biogenesis and metabolism 94 Collagen and hydroxyproline 95 Proteins and peptides 95 Amino acid uptake by animal tissues 96 Biosynthesis of phospholipids and other lipids- 97 Vitamin B 12 97 Development of analytical procedures 98 Section on biochemical genetics 98 RNA and genetic code 98 Cell-free assay for messenger RNA. (nih.gov)

The six ferredoxin (Fdx) and four flavoprotein Fdx reductase (FDR) proteins coded by genes in S. coelicolor were expressed in Escherichia coli, purified, and used to characterize the electron transfer pathway. (nih.gov)

The existence of iron-sulfur cluster proteins was investigated through various sources such as photosynthetic organisms, nitrogen-fixing bacteria, mammalian mitochondrial codons. (alliedacademies.org)
16. Effect of mitochondrial complex I inhibition on Fe-S cluster protein activity. (nih.gov)
iii) Deletion of amino acids 2-15 from the putative targeting presequence of Cpn60 leads to an accumulation of the truncated protein in the cytosol, a phenotype that can be reversed by the addition of a functional mitochondrial targeting signal from Trypanosoma cruzi Hsp70 to the truncated protein [ 8 ]. (biomedcentral.com)
Acyl-ACP-LYRM protein complexes facilitate assembly of mitochondrial respiratory complexes. (nature.com)
Two acyl-ACP molecules can be found associated with LYRM proteins as components of complex I in the mitochondrial RC. (nature.com)
As the multiple mitochondrial functions are mutually interconnected, changes in protein composition by mutations or in supercomplex assembly and/or in membrane structures often generate a dysfunctional cascade and lead to life-incompatible diseases or severe syndromes. (researchgate.net)
The known structural/functional changes in mitochondrial proteins and structures, which impact mitochondrial bioenergetics because of an impaired or defective energy transduction system, here reviewed, constitute the main biochemical damage in a variety of genetic and age-related diseases. (researchgate.net)

10. The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. (nih.gov)
12. Iron-sulfur protein maturation in human cells: evidence for a function of frataxin. (nih.gov)
Iron-sulfur protein maturation in Helicobacter pylori:Identifying a Nfu-type cluster carrier protein and its iron-sulfur protein targets. (uga.edu)
The maturation of FeS proteins in eukaryotes is an essential function of mitochondria, but little is known about this process in amitochondriate eukaryotes. (biomedcentral.com)
Insertion of ligands and correct folding of nickel-iron hydrogenases require assistance of accessory maturation proteins (encoded by the hyp -genes). (biomedcentral.com)
The intergenic region between the structural genes encoding the uptake hydrogenase ( hupSL ) and the accessory maturation proteins ( hyp genes) in the cyanobacteria Nostoc PCC 7120 and N. punctiforme were analysed using molecular methods. (biomedcentral.com)
The five ORFs upstream of the hyp -genes in several filamentous N 2 -fixing cyanobacteria have an identical genomic localization, in between the genes encoding the uptake hydrogenase and the maturation protein genes. (biomedcentral.com)

Research on Fe-S cluster biosynthesis in the Johnson group currently involves investigating the molecular mechanisms of Fe-S cluster assembly on scaffold proteins and the subsequent intact cluster transfer to acceptor or carrier proteins. (uga.edu)

We developed two signature patterns for these proteins: the first corresponds to the core of the iron-sulfur binding domain, the second corresponds to the best conserved region in the catalytic core of these enzymes. (expasy.org)
creates a toxic condition, which directly alters the stability of various lipids, proteins, enzymes of critical metabolic pathways, replication, transcription, and translation machinery, which makes it difficult for the micro organisms to survive [ 70 , 73 ]. (sciendo.com)
MtFAS follows the prokaryotic type II mode where individual enzymatic steps are carried out by separate enzymes (Fig. 1a ) Acyl groups synthesized by mtFAS are linked to 4-phosphopantetheine moiety of the acyl carrier protein (ACP) via a thioester bond. (nature.com)
At this time crystallization was used as a purification tool and allowed James B. Sumner and John H. Northrop to show that the catalytic power of enzymes resides in the protein itself and not in organic catalysts adsorbed on the protein surface. (iucr.org)

4-Hydroxy-3-methylbut-2-enyl diphosphate reductase (EC 1.17.1.2, isopentenyl-diphosphate:NADP+ oxidoreductase, LytB, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase, HMBPP reductase, IspH, LytB/IspH) is an enzyme in the non-mevalonate pathway. (wikipedia.org)

The iron-sulphur cluster (ISC) assembly system in mitochondria is the primary machinery for Fe-S cluster synthesis in eukaryotes. (alliedacademies.org)
Functional expression of L-lysine alpha-oxidase from Scomber japonicus in Escherichia coli for one-pot synthesis of L-pipecolic acid from DL-lysine │ Appl. (ritsumei.ac.jp)
However, they do not explicitly account for the synthesis of macromolecules (i.e., proteins and RNA). (ucsd.edu)
Essential processes such as DNA replication, RNA transcription and protein synthesis are functional in Escherichia coli up to at least 500, 200 and 600 bar, respectively [ 26 ]. (biomedcentral.com)
137 Folic acid 138 Large-scale laboratory 138 Germ-free program 138 Laboratory of physical biology 139 Physiology 139 Molecular structure 139 Protein structure, activity, synthesis 140 Biological energy 140 Laboratory of chemistry 141 Rotatory dispersion of nucleosides 141 Cz's-nucleosides 141 Octuloses and nonuloses 142 Anhydroheptuloses 142 Rearrangements of cyclitols 142 Glycosyl cyanides 142 Benzomorphans 142 Phenolic hydroxyl in a- and ^-benzomorphans. (nih.gov)

Escherichia coli endonuclease III (EC 4.2.99.18 ) (gene nth) [ 1 ] is a DNA repair enzyme that acts both as a DNA N-glycosylase, removing oxidized pyrimidines from DNA, and as an apurinic/apyrimidinic (AP) endonuclease, introducing a single-strand nick at the site from which the damaged base was removed. (expasy.org)
The 3-D structures of Escherichia coli endonuclease III [ ( PUBMED:1411536 ) ] and catalytic domain of MutY [ ( PUBMED:9846876 ) ] have been determined. (embl-heidelberg.de)

Iron-Dependent Regulation of Molybdenum Cofactor Biosynthesis Genes in Escherichia coli. (mpg.de)

8. Regulation of iron homeostasis by the p53-ISCU pathway. (nih.gov)
Structural characterization of an iron-sulfur cluster assembly protein IscU in a zinc-bound form. (nih.gov)
The IscU protein differs significantly from other eukaryotic homologs and resembles the long type isoforms encountered in some bacteria. (biomedcentral.com)

The membrane anchor of SQR in mammalian mitochondria and proteobacteria, such as Escherichia coli , consists of two polypeptides (SdhC and SdhD) and contains one heme group. (lu.se)
7. Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells. (nih.gov)
Surprisingly, the iron content of E. coli and its reactivity with O 2 were remarkably similar to those of mitochondria. (sc.edu)
Given the universality of oxidative phosphorylation in aerobic biology, the iron content and respiratory shield in other aerobic prokaryotes might be similar to those of E. coli and mitochondria. (sc.edu)

The ABCB7-Like Transporter PexA in Rhodobacter capsulatus Is Involved in the Translocation of Reactive Sulfur Species. (mpg.de)
Bicaudal-C (Bicc1) is an RNA binding protein that functions as translational repressor in all animal species. (wisconsin.edu)
From solution conditions in which the protein is in its native state, a distribution of monomeric, dimeric, and tetrameric species was observed. (ox.ac.uk)
Despite the molecular mass of the noncovalent dimer (77 kDa), it was possible to observe a dimeric species containing one iron-sulfur cluster in both positive and negative ion spectra. (ox.ac.uk)
Proteins obtained from species of fish (FISHES). (lookformedical.com)

Two unexpected promiscuous activities of the iron-sulfur protein IspH in production of isoprene and isoamylene. (cmdm.tw)

Within these elaborate protein complexes, BMC-domain shell proteins [bacterial microcompartment (in reference to the shell protein domain)] assemble to form a polyhedral barrier that encapsulates the enzymatic contents of the MCP. (rcsb.org)
Analysis of cytosolic extracts by size-exclusion chromatography detected by an online inductively-coupled plasma mass spectrometer revealed a low-molecular-mass ( 4 LMM) Fe II pool consisting of two iron complexes with masses of ~ 500 (major) and ~1300 (minor) Da. (sc.edu)
In both cases, a "respiratory shield" composed of membrane-bound iron-rich respiratory complexes may protect the LMM Fe II pool from reacting with O 2 . (sc.edu)
Acyl-ACPs form complexes with adapter proteins that contain a leucine-tyrosine-arginine motif (LYRM) 6 . (nature.com)

Iron is critical for virtually all organisms, yet major questions remain regarding the systems' level understanding of iron in whole cells. (sc.edu)
Iron-sulfur (FeS) proteins are present in all living organisms and play important roles in electron transport and metalloenzyme catalysis. (biomedcentral.com)
This include bacterial contamination by Gram-positive Bacilli, Staphylococcus aureus and non Escherichia coli Gram-negative organisms. (moldbacteria.com)

Medicinal plant extracts protect epithelial cells from infection and DNA damage caused by colibactin-producing Escherichia coli, and inhibit the growth of bacteria. (ritsumei.ac.jp)
While in bacteria the different oxygen-sensing pathways reported involve protein dimerization and phosphorylation cascades, in plants and animals this function is mediated by oxygen-dependent proteolysis. (springer.com)
Purification of (4Fe-4S)1-2-ferredoxins (high-potential iron-sulfur proteins) from bacteria. (microbiologyresearch.org)
Water can also be analysed for other types of bacteria such as iron, sulfur or slime bacteria that cause blockage of plumbing systems, bad odors, discolorations and diseases. (moldbacteria.com)

The NEET family protein NAF-1 plays emerging roles in iron homeostasis, autophagy, cell death pathways, and regulating cellular resistance to oxidative stress. (alliedacademies.org)
Nick's research interests lie in understanding how bacterial cells handle essential metal ions, the pathways by which metal-containing proteins are assembled, and the reactivities associated with metalloproteins. (uea.ac.uk)
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures. (cmdm.tw)
Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production. (cmdm.tw)
Aside from commercial value, appropriately designed proteins can also be helpful in the dissection of the physiological function of particular pathways. (nature.com)

Direct observation of an iron-bound terminal hydride in [FeFe]-hydrogenase by nuclear resonance vibrational spectroscopy. (nature.com)
One of the specific aims of this research is to establish how the special structures of the active sites of the two kinds of hydrogenase (one contains only iron, the other contains iron and nickel) perfected by biology during over two billion years of evolution, lead to such high activity. (ukri.org)

The gene encoding a putative high-potential iron-sulfur protein (HiPIP) from the strictly acidophilic and chemolithoautotrophic Acidithiobacillus ferrooxidans ATCC 33020 has been cloned and sequenced. (microbiologyresearch.org)
The R. sphaeroides napK gene codes for a putative 6.3 kDa transmembrane protein which is not similar to known proteins and the napE gene codes for a 6.7 kDa transmembrane protein similar to the Thiosphaera pantotropha NapE. (bvsalud.org)
Putative multidrug export ATP-binding/permease protein SAV1866 (EC 7.6.2. (weizmann.ac.il)

Translocation of this protein in the periplasm of E. coli was not detected in a Δ tatC mutant, indicating that it is dependent on the Tat system. (microbiologyresearch.org)
Export pathway selectivity of Escherichia coli twin arginine translocation signal peptides. (ecmdb.ca)

MutY is a larger protein (350 amino acids) than endonuclease III (211 amino acids). (expasy.org)
GrpU is one such shell protein whose amino acid sequence is particularly divergent from other members of the BMC-domain superfamily of proteins that effectively defines all MCPs. (rcsb.org)
Aoyama, J.J., Raina, M., Zhong, A. and Storz, G. (2022) Dual-function Spot 42 RNA encodes a 15-amino acid protein that regulates the Crp transcription factor. (nih.gov)
The fruiting bodies of the Reishi mushroom are a magnificent source of nutritionally important minerals , vitamins (mainly B-complex vitamins and vitamin D ), antioxidants , amino acids, macronutrients, as well as protein (despite not being animal-based). (ecosh.com)
Mushroom proteins contain all the essential amino acids and are especially rich in lysine and leucine. (ecosh.com)

2019). Epigenetic regulation of sulfur homeostasis in plants. (nottingham.ac.uk)

If the membrane-anchor is missing or defective, Fp and Ip subunits accumulate as soluble proteins in the cytoplasm. (lu.se)

In the mid-1960s, it was revealed that these proteins contain a complex of iron and cysteine sulfur atoms [ 1 ].More data on their electronic and geometric structure was obtained later and it was shown that they are analogs of the active site of proteins. (alliedacademies.org)
The cluster is bound entirely within the C-terminal loop by four cysteine residues with a ligation pattern Cys-(Xaa)6-Cys-(Xaa)2-Cys-(Xaa)5-Cys which is distinct from all other known Fe4S4 proteins. (embl-heidelberg.de)
MutY contains a solvent-exposed polypeptide loop between two of the cysteine ligands to the [4Fe-4S](2+) cluster, referred to as the iron-sulfur cluster loop (FCL) motif. (embl-heidelberg.de)

As shown by optical and EPR spectra and by electrochemical studies, the recombinant protein has all the biochemical properties of a HiPIP, indicating that the iron-sulfur cluster was correctly inserted. (microbiologyresearch.org)
Here, we obtained Mössbauer and EPR spectra of Escherichia coli cells prepared under different nutrient iron concentrations, carbon sources, growth phases, and O 2 concentrations to better understand their global iron content. (sc.edu)

Peters, J. W. & Broderick, J. B. Emerging paradigms for complex iron-sulfur cofactor assembly and insertion. (nature.com)
3. Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. (nih.gov)
4. Human ISD11 is essential for both iron-sulfur cluster assembly and maintenance of normal cellular iron homeostasis. (nih.gov)
Nevertheless, differential transcription was observed for a few genes linked to iron-sulfur cluster assembly, terminal oxidases, glutamate metabolism and arginine deiminase pathway, which shows their particular sensitivity to variations of DOT. (biomedcentral.com)
In this quest, the analysis of packing contacts and contacts within oligomers will be crucial in order to decipher the rules governing protein self-assembly and will guide the engineering of novel biomaterials. (iucr.org)

Separately, the unknown contigs were also translated using all possible open reading frames and subsequently processed with SUPERFAMILY version 1.75 ( 13 ) to identify potential homologies with known proteins. (cdc.gov)

Genetic analysis of tellurate reduction reveals the selenate/tellurate reductase genes ynfEF and the transcriptional regulation of moeA by NsrR in Escherichia coli. (ritsumei.ac.jp)
Alexeeva S, Hellingwerf KJ, Teixeira de Mattos MJ (2003) Requirement of ArcA for redox regulation in Escherichia coli under microaerobic but not anaerobic or aerobic conditions. (springer.com)

So the E. coli have to survive under the presence of ROS and RNS that can specifically damage bacterial lipids, proteins, and DNA. (sciendo.com)

Escherichia coli and related protein DNA repair protein mutY, which is an adenine glycosylase. (expasy.org)
Escherichia coli MutY is an adenine glycosylase involved in base excision repair that recognizes OG:A (where OG = 7, 8-dihydro-8-oxo-2'-deoxyguanosine) and G:A mismatches in DNA. (embl-heidelberg.de)

Overexpression and characterization of Escherichia coli dihydropyrimidine dehydrogenase: a four iron-sulphur cluster containing flavoprotein. (ritsumei.ac.jp)
Genome-scale reconstruction of Escherichia coli's transcriptional and translational machinery: a knowledge base, its mathematical formulation, and its functional characterization. (ucsd.edu)

Yeast hypothetical protein YAL015c. (expasy.org)
Fission yeast hypothetical protein SpAC26A3.02. (expasy.org)

Initially in the 1960s, information about them was at the level of a group of unknown proteins that contained iron atoms and had a role in redox functions. (alliedacademies.org)
An extra 30 seconds in a hot pan can give those nasty sulfur atoms the time they need to stink up the joint. (lebendigefluesse.at)

Endonuclease III is an iron-sulfur protein that binds a single 4Fe-4S cluster. (expasy.org)

Egg yolks have trace amounts of iron, and egg whites have sulfur compounds. (lebendigefluesse.at)
Conjugated protein-carbohydrate compounds including mucins, mucoid, and amyloid glycoproteins. (lookformedical.com)

Comparative analyses with reference genomes and the transcripts of functional genes posit an expanded role for Bathyarchaeota in phototrophy, autotrophy, and nitrogen and sulfur cycles, respectively. (biomedcentral.com)

Positively charged residues within the iron-sulfur cluster loop of E. coli MutY participate in damage recognition and removal. (embl-heidelberg.de)

This iron-sulphur protein shows similarity to the NapF and NapG proteins of E. coli and Haemophilus influenzae. (bvsalud.org)

We determined X-ray crystal structures of two GrpU orthologs, providing the first structural insight into the homohexameric BMC-domain shell proteins of the Grp system. (rcsb.org)

Olejniczak, M. and Storz, G. (2017) ProQ/FinO-domain proteins: another ubiquitious family of RNA matchmakers? (nih.gov)

15. Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization. (nih.gov)

In contrast, hydrogenases catalyse the interconversion between hydrogen gas and protons (water) at rates and efficiencies higher than platinum but using the common elements iron and nickel. (ukri.org)

Proteins that contain metal ions (metalloproteins) constitute a diverse and hugely important group. (uea.ac.uk)

The X-ray structures of GrpU, both obtained in the apo form, combined with spectroscopic analyses and computational modeling, show that the metal cluster resides in the central pore of the BMC shell protein at a position of broken 6-fold symmetry. (rcsb.org)
At present, a diversified panel of crystallization methods adapted to proteins has been validated, and although only a few methods are in current practice, the success rate of crystallization has increased constantly, leading to the determination of ∼10 5 X-ray structures. (iucr.org)
These structures reveal a huge repertoire of protein folds, but they only cover a restricted part of macromolecular diversity across the tree of life. (iucr.org)
A subclass of ANTIFREEZE PROTEINS that are globular, 6.5 kDa in size and contain compact beta-sheet structures. (lookformedical.com)

Additionally, constitutively expressed ERF-VII proteins, such as RAP2.12, are bound to the acyl-CoA-binding proteins (ACBPs) at the plasma membrane and protected from aerobic degradation. (springer.com)

Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. (ecmdb.ca)

Insect juvenile hormone (JH) and its hemolymph transport protein, juvenile hormone binding protein (JHBP) play key roles in the development of many insects. (wisconsin.edu)

Fatty acids serve a living organism as building blocks of biomembranes, energy storage, cell signaling molecules and ligands in post-translational protein modification. (nature.com)

One of them is coupled to a complete denitrifying pathway, and the other is a periplasmic protein whose physiological role seems to be the dissipation of excess reducing power, thus improving photoanaerobic growth. (bvsalud.org)

Here we report on the identification and analysis of two genes encoding critical FeS cluster (Isc) biosynthetic proteins from the amitochondriate human pathogen Entamoeba histolytica . (biomedcentral.com)

Anatomy1

Organisms3

Diseases2

Chemicals and Drugs22

Analytical, Diagnostic and Therapeutic Techniques and Equipment2

Phenomena and Processes7

Information Science3

Clusters16

Biogenesis11

Expressed in Escherichia coli1

Mitochondrial7

Maturation7

Scaffold proteins1

Enzymes4

Oxidoreductase1

Synthesis5

Coli endonuclease2

Biosynthesis1

ISCU3

Mitochondria4

Species5

IspH1

Complexes4

Organisms3

Bacteria4

Pathways5

Hydrogenase2

Putative3

Translocation2

Amino5

20191

Cytoplasm1

Cysteine3

Spectra2

Assembly5

Known proteins1

Regulation2

Lipids1

Adenine glycosylase2

Characterization2

Yeast2

Atoms2

Binds1

Compounds2

Nitrogen1

MutY1

NapG1

Structural1

20171

Regulatory1

Hydrogenases1

Metal Ions1

Structures4

Aerobic1

MG16551

Roles1

Ligands1

Pathway1

Biosynthetic1