Escherichia coli inner membrane coli membrane protein. Medical search. Frequent questions

This asymmetry is maintained by the Mla pathway, a six-component system that is widespread in Gram-negative bacteria and is thought to mediate retrograde transport of misplaced phospholipids from the outer leaflet of the OM to the cytoplasmic membrane 4 . (nature.com)
However, the production of proteins in its cytoplasmic membrane or periplasm is challenging. (dissertations.se)
TonB, partner protein of FhuA, is one of three proteins from the energy-transducing complex TonB-ExbB-ExbD that is embedded in the cytoplasmic membrane. (mcgill.ca)
We investigate the mobility of proteins in the bacterial cytoplasm and cytoplasmic membrane as well as membrane model systems, using optical microscopy-based techniques such as fluorescence correlation spectroscopy (FCS) and pulsed-FRAP (panel a). (rug.nl)
either the cytoplasmic membrane or the cytosol. (nottingham.ac.uk)

Colicins are protein antibiotics produced by strains of Escherichia coli to kill non-producing strains of the same organims presumably as a method of competitive inhibition. (nottingham.ac.uk)
Bacteriocins are protein antibiotics produced by strains of bacteria that are active against related bacteria. (nottingham.ac.uk)
1] "Identification of genes subject to positive selection in uropathogenic strains of Escherichia coli: a comparative genomics approach. (tcdb.org)
5] "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. (tcdb.org)
Neonatal sepsis can be caused by bacteria such as Escherichia coli ( E coli ), Listeria , and some strains of streptococcus. (medlineplus.gov)

Bicistronic Design-Based Continuous and High-Level Membrane Protein Production in Escherichia coli. (mpg.de)

The tolZ gene of Escherichia coli is identified as the ftsH gene. (wikigenes.org)

Nucleotide sequences of the fumarase (fumC) and aspartase (aspA) genes of Escherichia coli K12. (tcdb.org)

How does crowding affect mobility of proteins and lipids? (rug.nl)
Small angle neutron scattering (SANS) provides unique insight into biomacromolecular complexes by combining solvent contrast variation (H2O:D2O exchange) with either natural contrast between different classes of biomolecules (proteins, RNA/DNA, lipids/detergents) and/or by applying artificial contrast, i.e. deuteration of specific biomolecules. (lu.se)

High molecular weight biomolecules have so far dominated the field of protein-derived therapeutics in many areas. (boku.ac.at)
Given their small size and (relatively) low molecular weight, peptides have certain advantages over large proteins and antibodies. (boku.ac.at)
Recombinant expression in Escherichia coli could potentially circumvent these issues and offers a platform for efficient production of low molecular weight peptides. (boku.ac.at)

However, most proteins in the human proteome lack small-molecule probes, including the large class of non-catalytic transmembrane receptors, such as death receptors. (rcsb.org)
A quarter of the E. coli proteome is extracytoplasmic, targeted to a final destination by short, canonical N-terminal sequences that for the most part direct them either to the general secretory or Tat pathway machines. (nottingham.ac.uk)
10] "Global topology analysis of the Escherichia coli inner membrane proteome. (tcdb.org)

One of the ABC transporters that is studied in detail is the osmoregulatory ABC transporter OpuA (class D). Osmotic control of OpuA involves gating by intracellular ionic strength and is mediated by lipid-protein interactions. (rug.nl)
A structural genomics approach is used to determine to the structures of proteins belonging to other classes of ABC transporters. (rug.nl)
This ability to exploit structure within a pre-protein is an unexplored area of protein transport, which may apply to other protein transporters, such as those of the endoplasmic reticulum and mitochondria. (elifesciences.org)
2] "Escherichia coli possesses two homologous anaerobic C4-dicarboxylate membrane transporters (DcuA and DcuB) distinct from the aerobic dicarboxylate transport system (Dct). (tcdb.org)

Kocer, A., Walko, M., and Feringa, B.L. (2007) Synthesis and utilization of reversible and irreversible light-activated nanovalves derived from the channel protein MscL. (rug.nl)
In the body, these toxins inhibit protein synthesis leading to cell death. (cdc.gov)

Herein is described procedures implemented in the Caffrey Membrane Structural and Functional Biology Group to harvest and cryo-cool membrane protein crystals grown in lipidic cubic and sponge phases for use in structure determination using macromolecular X-ray crystallography. (jove.com)
Structural evidence that colicin A protein binds to a novel binding site of TolA protein in Escherichia coli periplasm Journal of Biological Chemistry. (nottingham.ac.uk)
Protein separation conditions always pose the risk of denaturation or structural alteration of the LF molecule. (ift.org)
In a first couple of examples, I will show how distance and shape restraints from SANS have helped to improve the uniqueness of structural models for two multi-protein-RNA complexes, in combination with NMR restraints and building blocks from crystallography [1, 2]. (lu.se)

From there, the mature proteins are either targeted to the outer membrane, or remain as periplasmic proteins. (wikipedia.org)
The CusB protein is part of the CusCBA periplasmic Cu(I) efflux system in Gram-negative bacteria, and it was recently reported to play a key role in the functioning of the whole CusCBA system, in which conformational changes as well as the assembly/disassembly process control the opening of the transporter. (biorxiv.org)

The translocase itself comprises 7 proteins, including a chaperone protein (SecB), an ATPase (SecA), an integral membrane complex (SecCY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD and SecF). (wikipedia.org)

Protein components in the matrix partake in energetically driving translocation in a reaction that depends on the membrane potential and matrix-ATP. (nih.gov)
Molecular chaperones in the matrix exert multiple functions in translocation, sorting, folding, and assembly of newly imported proteins. (nih.gov)
Unlike the SecD subunit of the pre-protein translocase of E. coli, SecDF of B. subtilis was not required for the release of a mature secretory protein from the membrane, indicating that SecDF is involved in earlier translocation steps. (wikipedia.org)
Here we show, using X-ray crystallography, molecular dynamics simulations and in vitro and in vivo functional assays, that MlaA is a monomeric α-helical OM protein that functions as a phospholipid translocation channel, forming a ~20-Å-thick doughnut embedded in the inner leaflet of the OM with a central, amphipathic pore. (nature.com)
In prokaryotes, SecYEG associates with the motor ATPase SecA to carry out translocation for pre-protein secretion. (elifesciences.org)
This paper explores how the protein folding process per se may be exploited to drive protein translocation. (elifesciences.org)
The protein must then fold during or after the translocation process. (elifesciences.org)
4) Protein translocation across membranes. (nottingham.ac.uk)

Over the years, the view on proteases as relatively non-specific protein degradation enzymes, mainly involved in food digestion and intracellular protein turnover, has shifted and they are now recognized as key regulators of many biological processes that determine the fate of a cell. (dissertations.se)
The accumulation of FtsY-ribosome complexes induces the formation of intracellular membranes needed for their quantitative accommodation. (rupress.org)
Our results with E. coli , in conjunction with recent observations made with the yeast Saccharomyces cerevisiae , raise the possibility that the SRP receptor-mediated formation of intracellular membrane networks is governed by evolutionarily conserved principles. (rupress.org)
While the molecular nature of intracellular cobalamin metabolism in mammals remains poorly understood, the proteins MMACHC, MMADHC, LMBD1 and ABCD4 are implicated in its early uptake and processing. (mcgill.ca)

Protein stabilization upon ligand binding has frequently been used to identify ligands for soluble proteins. (nih.gov)
Unlike crystals that are grown for soluble proteins (usually to 100 µm in size), the MP crystals of the ExbB-ExbD complex that we reproducibly grow in lipidic cubic phase are "showers", only 5 to 10 µm in all dimensions. (mcgill.ca)
If the membrane-anchor is missing or defective, Fp and Ip subunits accumulate as soluble proteins in the cytoplasm. (lu.se)

They are members of the rBAT family of mammalian proteins (TC #8.A.9). (tcdb.org)
The membrane anchor of SQR in mammalian mitochondria and proteobacteria, such as Escherichia coli , consists of two polypeptides (SdhC and SdhD) and contains one heme group. (lu.se)

Escherichia coli (E. coli) is the most widely used bacterium for the production of recombinant proteins. (dissertations.se)
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. (gentaur.com)

The high-affinity interaction of LF with pore-forming outer-membrane proteins (OMPs) of Gram-negative enterics, including Escherichia coli , is critical for the antimicrobial outcome of LF (Gado et al. (ift.org)

In derivatives of this strain which contain only one of these proteins in large amounts a strong decrease of the number of intramembraneous particles is observed, which is accompanied by a complete restoration of the rate of uptake of those solutes which use pores in which the protein in question is involved. (uu.nl)
The reason for the observed defective assembly in E. coli is probably not some unidentified mutation in the plasmid DNA because the same plasmid preparation complemented a B. subtilis sdhCAB deletion strain [7]. (lu.se)

Secretion across the inner membrane in some Gram-negative bacteria occurs via the preprotein translocase pathway. (wikipedia.org)
SecB maintains preproteins in an unfolded state after translation, and targets these to the peripheral membrane protein ATPase SecA for secretion. (wikipedia.org)
The SecD and SecF equivalents of the Gram-positive bacterium Bacillus subtilis are jointly present in one polypeptide, denoted SecDF, that is required to maintain a high capacity for protein secretion. (wikipedia.org)
The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or eukaryotic cells via a contractile mechanism. (frontiersin.org)
The encapsulation and compartmentalisation of cells has necessitated the evolution of machineries that conduct proteins across membranes, including for protein secretion and organellar import. (elifesciences.org)
The bulk of protein secretion and membrane protein insertion is conducted by the ubiquitous Sec translocon. (elifesciences.org)
CdiA secretion is dependent on the outer membrane protein CdiB. (nih.gov)
Selective stimulation of extra-placental membranes with E. coli , results in a tissue specific secretion of HBD1, HBD2, and HBD3 mainly in the CHD, which is the first infected region during an ascending infection. (biomedcentral.com)

The SecDF protein of B. subtilis has 12 putative transmembrane domains. (wikipedia.org)
Panning combinatorial phage libraries against recombinant MMADHC allowed mapping of putative sites of interaction on each protein. (mcgill.ca)
1] "Construction and properties of Escherichia coli mutants defective in two genes encoding homologous membrane proteins with putative roles in anaerobic C4-dicarboxylic acid transport. (tcdb.org)

The structure provides an explanation for assembly and insertion of the lipoprotein molecules into the outer membrane of gram-negative bacteria and suggests a molecular target for antibacterial drug discovery. (rcsb.org)
MlaC probably accepts a phospholipid from MlaA and shuttles it to the ABC transporter for ATP-dependent plasma membrane insertion 5 . (nature.com)
Waveguides functionalized with phospholipid bilayers were used to pull down amphiphilic LPS, using methods (membrane insertion) developed by our team. (spie.org)
Some animal proteins, for example, those in the LAT family (TC# 2.A.3.8) including ASUR4 (gbY12716) and SPRM1 (gbL25068) associate with a type 1 transmembrane glycoprotein that is essential for insertion or activity of the permease and forms a disulfide bridge with it. (tcdb.org)

3] "Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. (tcdb.org)
4] "The complete genome sequence of Escherichia coli K-12. (tcdb.org)

Three different preformed lipid membranes of phosphatidylcholine were prepared to compare the folding kinetics of OmpA, namely, proteoliposomes containing either BamA or FomA and pure liposomes. (uni-konstanz.de)

Escherichia coli S-fimbriae and outer membrane protein A (OmpA) have been shown to promote binding and invasion of E. coli to brain microvascular endothelial cells, respectively. (johnshopkins.edu)
Using the cranial window model, we compared the response of pial arterioles in experimental animals exposed to E. coli with and without S-fimbriae or OmpA after intracarotid injection to animals receiving saline (control). (johnshopkins.edu)
After 3 h, pial arteriolar diameter progressively increased to 156 ± 14% of baseline in animals exposed to OmpA + E. coli and 151 ± 24% of baseline to OmpA - E. coli. (johnshopkins.edu)
The vasodilatory response to OmpA + and OmpA - E. coli was statistically different from control (p = 0.0004 and 0.0010, respectively) but not different from each other. (johnshopkins.edu)
Here, folding was studied for a β-barrel membrane protein, outer membrane protein A (OmpA) from Escherichia coli, in the absence and presence of two other preinserted integral proteins, BamA of the β-barrel assembly machinery complex (BAM) from E. coli and FomA from Fusobacterium nucleatum. (uni-konstanz.de)

While some effector proteins specifically target bacterial or eukaryotic cells, others can target both types of cells (trans-kingdom effectors). (frontiersin.org)
In addition, there is limited information regarding the repertoire of effector proteins encoded within T6SS SPI-6 and T6SS SPI-19 gene clusters in S . Dublin. (frontiersin.org)
This model represents the C-terminal (CT) toxin domain of CdiA effector proteins. (nih.gov)

However, finding a generic method that is applicable to membrane proteins has been a challenge as the high hydrophobicity of membrane proteins and the presence of detergents essential for their solubilization interfere with fluorescence-based detections. (nih.gov)
Here the authors used MsbA (an adenosine triphosphate binding cassette transporter), CorA (a Mg(++) channel), and CpxA (a histidine kinase) as model proteins and show that DSLS is not sensitive to the presence of detergents or protein hydrophobicity and can be used to monitor thermodenaturation of membrane proteins, assess their stability, and detect ligand binding in a 384-well format. (nih.gov)

Here we show that in cells depleted of the SRP protein, Ffh or the translocon component SecE, the ribosomal targeting pathway is blocked downstream and unprecedented, membrane-bound FtsY-ribosomal complexes are captured. (rupress.org)
For import of iron-siderophore complexes, seven proteins in the cell envelope of Escherichia coli are essential. (mcgill.ca)

Through a bacterial two-hybrid library screen, we identified the E. coli β-lactam resistance protein Blr, a short membrane polypeptide of 41 residues, as an interacting partner of the essential cell division protein FtsL. (pasteur.fr)

Proteins are produced in the cytoplasm as precursors, and require a chaperone subunit to direct them to the translocase component. (wikipedia.org)
The chaperone protein SecB is a highly acidic homotetrameric protein that exists as a "dimer of dimers" in the bacterial cytoplasm. (wikipedia.org)

Methods such as differential scanning fluorimetry (DSF) and differential static light scattering (DSLS) have been employed in the 384-well format and have been useful in identifying ligands that promote crystallization and 3D structure determination of proteins. (nih.gov)

Crystal structure of the membrane fusion protein CusB from Escherichia coli. (harvard.edu)

Recently, it has been recognized that membrane-bound ribosomes are crucial for biogenesis of integral membrane proteins in E. coli , thus renewing interest in ribosome targeting to and association with the membrane in this organism. (rupress.org)
Furthermore, outer membrane permeability of the host organism(s) will be adjusted in-process using moleculobiological tools. (boku.ac.at)
SQR consists of a membrane-peripheral heterodimer domain (often called succinate dehydrogenase) which is tightly bound to a membrane-spanning anchor, which is a cytochrome with one or two heme groups depending on the organism. (lu.se)

Flavinylation of Fp in B. subtilis does not require the Ip subunit or the membrane anchor but depends on folding of the Fp polypeptide into a state that can bind FAD and subsequent mediate covalent binding of the FAD [3, 4]. (lu.se)
In the Fp subunit of SQR, and the closely related membrane-associated fumarate reductase of anaerobic organisms, FAD is covalently attached via an 8α-N(3)-histidyl linkage to a histidine (His) in a conserved sequence in the N-terminal part of the polypeptide. (lu.se)
The B. subtilis Fp polypeptide was found to lack covalently bound FAD when produced in E. coli although E. coli Fp in the same cell was flavinylated [8]. (lu.se)

We focus our studies on the chemotaxis systems within Pseudomonas aeruginosa , and seek to elucidate how protein localization is correlated to function. (uwm.edu)
Sueki A, Stein F, Savitski MM, Selkrig J * & Typas A* (2020) Systematic Localization of Escherichia coli Membrane Proteins. (ukaachen.de)

Some of these proteins exhibit 11 TMSs. (tcdb.org)

Mitochondria import many hundreds of different proteins that are encoded by nuclear genes. (nih.gov)
These proteins are targeted to the mitochondria, translocated through the mitochondrial membranes, and sorted to the different mitochondrial subcompartments. (nih.gov)

The impact of preinserted integral proteins from biomembranes has not been examined in biophysical comparisons, but this knowledge is important for the characterization of protein assembly machinery in membranes to distinguish specific effects from unspecific effects. (uni-konstanz.de)
Functional reintegration into lipid environments represents a major challenge for in vitro investigation of integral membrane proteins (IMPs). (tudelft.nl)

The hypothesis that intramembraneous particles, observed in the outer membrane of Escherichia coli by freeze-fracture electron microscopy, are the morphological representation of aqueous pores, was tested. (uu.nl)

The outer membrane lipoprotein of the Escherichia coli cell envelope has characteristic lipid modifications at an amino-terminal cysteine and can exist in a form bound covalently to the peptidoglycan through a carboxyl-terminal lysine. (rcsb.org)

The cell division genes ftsY, ftsE and ftsX form an operon mapping at 76 min on the Escherichia coli chromosome. (ox.ac.uk)
In Escherichia coli, cell division is performed by a multimolecular machinery called the divisome, made of 10 essential proteins and more than 20 accessory proteins. (pasteur.fr)
The Gram-negative bacterial outer membrane (OM) is a unique bilayer that forms an efficient permeation barrier to protect the cell from noxious compounds 1 , 2 . (nature.com)
The Coulton research group studies membrane proteins (MPs) that are required for transport of iron, an essential nutrient, across the bacterial cell envelope. (mcgill.ca)
The accompanying video shows a scale model for interaction of known proteins of E. coli that participate in transport of iron-siderophores across the cell envelope. (mcgill.ca)
The goal is to quantify and link outer membrane permeability to different mechanical properties of the cell. (boku.ac.at)
Overall, biologically active peptides should be produced extracellularly in soluble form by adjusting the membrane permeability of growing and producing cell. (boku.ac.at)
The first focuses on spatial organization of proteins within a bacterial cell. (uwm.edu)
We have proposed that under conditions of severe osmotic stress (panel b, lower figure), the cell membrane contacts the nucleoid, which creates pools of proteins and hinders free diffusion through the cell. (rug.nl)
The inset shows the confocal image of an E. coli cell with a computational grid superimposed. (rug.nl)
Panel b illustrates the effect of hyperosmotic stress on the proposed compartmentalization of an E. coli cell. (rug.nl)
Transport of proteins across membranes is a fundamental process, achieved in every cell by the 'Sec' translocon. (elifesciences.org)
Moreover, although the abundance of most protein groups reflected that of related bacterial populations, we found a specific independent regulation of bacteria-derived cell envelope proteins. (bmj.com)
These glycoproteins include the CD98 heavy chain protein of Mus musculus (gbU25708) and the orthologous 4F2 cell surface antigen heavy chain of Homo sapiens (spP08195). (tcdb.org)

Many proteins, largely derived from Bacteroides species, were over-represented, while under-represented proteins were mostly from Firmicutes and some Prevotella members. (bmj.com)
The results provide strong evidence for the notion that an individual pore contains only one protein species, a property which has been found earlier for individual particles. (uu.nl)

SecD and SecF are prokaryotic protein export membrane proteins. (wikipedia.org)
This family consists of various prokaryotic SecD and SecF protein export membrane proteins. (wikipedia.org)
The smaller proteins are generally of prokaryotic origin while the larger ones are of eukaryotic origin. (tcdb.org)

We propose that in the absence of a functional SRP or translocon, ribosomes remain jammed at their primary membrane docking site, whereas FtsY-dependent ribosomal targeting to the membrane continues. (rupress.org)

This work provides a conceptual framework for how microbes use a fluid outer membrane receptor to recognize and assemble kin cells into a cooperative multicellular community that resembles a tissue. (nature.com)
Previous in vivo studies indicated that unlike the E. coli signal recognition particle (SRP), the SRP receptor FtsY is required for membrane targeting of ribosomes. (rupress.org)

Once the pathogen reaches the uterine cavity, through an ascending pathway from the cervico-vaginal region, the extra-placental membranes are positioned critically between the normally sterile amniotic cavity and the contaminated extra-uterine environment [ 3 ]. (biomedcentral.com)

Nuclease colicins are also targeted but in the opposite direction, across both membrane barriers and by a mechanism that is insensitive to the structure of the imported enzyme. (nottingham.ac.uk)
Balanced biosynthesis of major membrane components through regulated degradation of the committed enzyme of lipid A biosynthesis by the AAA protease FtsH (HflB) in Escherichia coli. (wikigenes.org)
The lac operon of E. coli is but one example of how enzyme and transporter production can be made conditional on the presence of a nutrient to catabolize. (lu.se)

Associated membrane protein types are lipopolysaccharide selective barriers. (gentaur.com)
During an ascending infection along the reproductive tract, the extra-placental membranes must act as a selective and competent barrier against pathogens. (biomedcentral.com)

In the case of the lac operon of E. coli, a well-studied system for whether a gene is regulated. (lu.se)
The operon on plasmid in E. coli was found to result in the production of all three subunit polypeptides [7]. (lu.se)
However, the E. coli cells did not show increased succinate dehydrogenase activity nor did the operon complement a sdhCDAB defective E. coli mutant [7]. (lu.se)

Finally, the signal sequence is cleaved and the pre-protein is either folded or trafficked onwards. (elifesciences.org)
Bradley D, Viéitez C, Rajeeve V, Selkrig J , Cutillas PR & Beltrao P (2021) Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases. (ukaachen.de)
8] "Nucleotide sequence of the FNR-regulated fumarase gene (fumB) of Escherichia coli K-12. (tcdb.org)

They correspond to functions allowing opportunistic pathogens to colonise the mucus layers, breach the host barriers and invade the mucosae, which could still be aggravated by decreased host-derived pancreatic zymogen granule membrane protein GP2 in CD patients. (bmj.com)
How proteins are translocated across membrane barriers is a key issue in the biological and biomedical sciences. (nottingham.ac.uk)

Using multiple signal transduction schemes (including novel optical methods designed for amphiphiles), specific recognition antibodies, and a waveguide-based optical biosensor developed at Los Alamos National Laboratory, we have developed ultrasensitive detection methods for lipopolysaccharides (LPS), and protein biomarkers (Shiga toxin) of STEC in complex samples (e.g. beef lysates). (spie.org)

In a study of patients with type II cryoglobulinemia, peripheral blood mononuclear cells from 18 patients were separated into CD3+ (T cells), CD19+ (B cells), and CD14+ (monocytes) and analyzed for the presence of negative-strand HCV RNA and for HCV nonstructural protein 3 (NS3). (medscape.com)

The protocols describe the essential steps for obtaining diffraction quality crystals of a membrane protein starting from reconstitution of the protein in a lipidic cubic phase (LCP), finding initial conditions with LCP-FRAP pre-crystallization assays, setting up LCP crystallization trials and harvesting crystals. (jove.com)

Three systems are known to maintain OM lipid asymmetry: the OM phospholipase A 2 PldA 7 , the lipopolysaccharide (LPS) palmitoyl transferase PagP 8 and the Mla (maintenance of outer membrane lipid asymmetry) system. (nature.com)
A combination of molecular simulation with hydrogendeuterium-exchange mass spectrometry and electron paramagnetic resonance spectroscopy reveal an asymmetry across the membrane: ATP-induced conformational changes in the cytosolic cavity promote unfolded pre-protein structure, while the exterior cavity favours its formation. (elifesciences.org)

9] "Topological analysis of DcuA, an anaerobic C4-dicarboxylate transporter of Escherichia coli. (tcdb.org)

Anatomy27

Organisms21

Diseases4

Chemicals and Drugs101

Analytical, Diagnostic and Therapeutic Techniques and Equipment33

Phenomena and Processes73

Disciplines and Occupations1

Technology, Industry, Agriculture4

Information Science4

Health Care2

Cytoplasmic membrane5

Strains5

Production in Escherichia coli1

Gene of Escherichia coli1

Genes of Escherichia coli1

Lipids2

Molecular Weight3

Proteome3

Transporters4

Synthesis2

Structural4

Periplasmic2

Periplasm1

Translocation8

Intracellular4

Soluble proteins3

Mammalian2

Recombinant proteins2

Outer membrane proteins1

Strain2

Secretion8

Putative3

Insertion4

Genome2

Lipid membranes1

OMPA5

Effector proteins3

Detergents2

Complexes2

Residues1

Cytoplasm2

Ligands1

CusB1

Organism3

Polypeptide3

Localization2

TMSs1

Mitochondria2

Integral2

Electron microscopy1

LIPOPROTEIN1

Cell14

Species2

Prokaryotic3

Ribosomal1

Receptor2

Pathway1

ENZYME3

Selective2

Operon3

Sequence3

Barriers2

Signal Transduction1

Peripheral1

Lipidic cubic1

Asymmetry2

Transporter1