• During this ongoing education they have developed countless mechanisms to escape from the host's immune system. (ox.ac.uk)
  • Group A streptococcus (GAS) is a highly adapted, human-specific pathogen that is known to manipulate the immune system through various mechanisms. (lu.se)
  • My research interests focus on understanding virus-host interactions, factors for virus entry, pathogenicity and immunogenicity, mechanisms of viruses to evade immune system, humoral immune response and possibilities of vaccine development. (lu.se)
  • The overarching aim of my research is to understand the key mechanisms of HIV transmission and the rate of disease pathogenesis. (lu.se)
  • In contrast to its normal counterparts, the initiated cell can escape from cellular control mechanisms when responding to external or intercellular signals 5 . (bvsalud.org)
  • We aimed to understand molecular mechanisms of the intertwined interactions between tumour stromal components in metastasis and to provide a new paradigm for PDAC therapy. (bmj.com)
  • Hewins B, Richardson C, Rubino S, Kelvin A, Toloue Ostadgavahi A, Kelvin DJ (2022) Molecular mechanisms responsible for SARS-CoV-2 antibody waning and vaccine escape in Omicron sublineages BA.4 and BA.5. (jidc.org)
  • The international team of scientists, led by the Helmholtz Zentrum München (HMGU) in cooperation with Cardiff University (UK), the University of Pittsburgh (USA), Columbia University (USA), Karolinska Institute (Sweden), Ludwig-Maximilians-Universität München and Universität Regensburg, has now been able to unravel important molecular mechanisms that drive ferroptosis signaling. (sciencedaily.com)
  • Such mechanisms may indicate how the bacterium adapts tuberculosis strains from Beijing, China, shared a high to the host, a prerequisite for an enhanced accumulation of degree of similarity in IS 6110 restriction fragment length genomic mutations associated with resistance. (cdc.gov)
  • Oxidant damage to cellular DNA, proteins (including the epigenome), and lipids can occur when reactive oxygen species escape cell antioxidant and repair mechanisms. (who.int)
  • Definition and meaning of escape mechanism at MeaningMonkey.org. (meaningmonkey.org)
  • escape mechanism meaning and definition in the English Dictionary. (meaningmonkey.org)
  • Identifying a possible mechanism for genotype, such as the W strain, have been identified (4,5), increased adaptation of these bacteria to the human drug-susceptible variants of the W strain account for most immunologic host defense system or human interventions of this group of isolates characterized to date. (cdc.gov)
  • How addictions are confused as mechanisms to escape routes? (hindustantimes.com)
  • Herein, we delineate a novel and selective regulatory mechanism for these processes using efficient synthesis routes and resultant small chemicals as biological probes. (nature.com)
  • There should be at least two emergency escape routes in case of fire. (union.edu)
  • The pressure-driven mechanism occurs when radon escaping the soil encounters a negative pressure in the home relative to the soil. (cdc.gov)
  • To support developing tools that increase treatment efficacy by targeting mechanisms more directly, the current work examined potential distinctions in the neurophysiologies of escape and avoidance and tested how clinical anxiety affects these neurophysiologies. (okstate.edu)
  • Accumulating data also suggest that hypoxic stress in the tumor microenvironment promotes tumor escape mechanisms through the emergence of immune-resistant tumor variants and immune suppression. (nutriforce.cn)
  • Viral escape mechanisms--escapology taught by viruses. (ox.ac.uk)
  • Overall, this project will allow understanding the mechanism of the viral neurotropism, as well explain its immune evasion capacity. (pasteur.fr)
  • To illustrate the most common strategies of viral immune escape we have focused on two murine models of persistent infection, lymphocytic choriomeningitis virus (LCMV) and murine cytomegalovirus (MCMV). (ox.ac.uk)
  • This lifelong challenge has contributed to the development of numerous evasion mechanisms by Herpesviruses, many of which devoted to elude NK cell surveillance from viral reactivations rather than primary infections. (frontiersin.org)
  • LncRNA IFITM4P promotes immune escape by up-regulating PD-L1 via dual mechanism in oral carcinogenesis. (bvsalud.org)
  • Tumor suppressor genes code for proteins that inhibit cell division and growth, acting as a control mechanism to prevent excessive cell proliferation. (pharmiweb.com)
  • We identify a unique cell motility regulatory mechanism and synthesize a targeted therapeutic, providing a platform to pursue studies in humans. (nature.com)
  • Overall primary concerns are: extrapolating human clinical studies, seeding durable effective T cell resident memory (Trm), population human leucocyte antigen (HLA) coverage, and the potential for T cell-mediated immune escape. (mdpi.com)
  • Building frameworks outside the IHR Working Group and the INB will prejudice these negotiation processes and may result in less-accountable mechanisms. (who.int)
  • Moreover, they support adaptive responses via Ab-dependent mechanisms, triggered by CD16, and DC editing. (frontiersin.org)
  • The major mechanisms of recognition and effector responses employed by NK cells against Herpesviruses, related to their genomic organization will be addressed, including those allowing NK cells to generate memory-like responses. (frontiersin.org)
  • In particular, we use it to construct a mechanism for transmitting alerts undetectably in a message-passing system of n nodes. (nist.gov)
  • In particular, we use it to construct a mechanism for transmitting alerts. (nist.gov)
  • A contract to acquire, prototype construct, test, and evaluatue Mine Escape Vehicle (MEV) subsystem components along with their integration into the MEV vehicle platform. (cdc.gov)
  • Furthermore, we found that the same TNF defense mechanisms were instrumental in protecting wild-type adenovirus-infected human cells expressing 14.7K. This study describes a new molecular mechanism implemented by a virus to escape immunosurveillance by selectively targeting TNFR1 endocytosis to prevent TNF-induced DISC formation. (jci.org)
  • In addition, the mechanisms underlying virus reactivation or control will be discussed. (frontiersin.org)
  • In the study task, approximately 5.25-second cues predicted aversive images that could be avoided (blocked by a button press before image onset), escaped (ended by a button press after image onset), or not controlled. (okstate.edu)
  • Lastly, the study also shows some of the internal mechanisms that force retailers to discursively repackage sustainability talk into something that entails selling more, not less. (lu.se)
  • Performing under the name Cast of Thousands with Escape Mechanism, the rotating ensemble also worked exclusively with bits and pieces of the media environment, performing at art venues and performances spaces such as The Walker Art Center, the Soap Factory and The First Avenue Main Room. (wikipedia.org)
  • Escape Mechanism has collaborated with artists such as Steev Hise, The Tape-beatles and Wobbly, and mounted sound installations at art galleries such as The Blue Theater, Rosalux Gallery and The Rochester Art Center. (wikipedia.org)
  • Conclusions: Data suggest a specific effect of anxiety on fear system activation during preparation to escape aversion. (okstate.edu)
  • My system was feeling the odious signals and just wanted to shut down and escape, I guess. (hollywood-elsewhere.com)
  • A contract to evaluate a fiber optic sprinkler head emergency communications system to determine if this concept can meet the communication, tracking, mine escape, and rescue requirements of an underground communication system. (cdc.gov)
  • A contract to incorporate a wireless base station into the MagneLink Magnetic Communication System (MCS) and to develop a mechanism that automatically activates a portable wireless text messaging device when a refuge chamber is opened or deployed. (cdc.gov)
  • Use of a self-made water delivery system without an over-pressurization safety relief or other safety mechanism and inappropriate system components. (cdc.gov)
  • and 2) startle reflexes were inhibited during avoidance preparation, relatively enhanced during escape preparation, and further enhanced during uncontrollable anticipation, thus potentially reflecting fear-related activation. (okstate.edu)
  • This reveals the near impossibility for retailers and their sustainability talk to escape a potentially unsustainable status quo paradigm of sustainable development. (lu.se)
  • All commands should be escaped for CommandLineToArgV() - this mechanism is applied to each argument individually before it is appended to the command line string. (php.net)
  • This can especially occur during a temperature inversion, which reduces radon's escape potential from a building and thereby increases the indoor radon level. (cdc.gov)
  • The adenoviral protein E3-14.7K (14.7K) is an inhibitor of TNF-induced apoptosis, but the molecular mechanism underlying this protective effect has not yet been explained exhaustively. (jci.org)
  • ¹ See table 2 for height of escape mechanism corresponding to the minimum carapace size in effect. (gc.ca)
  • The height of the escape mechanism as indicated in Table 1 needs to be adjusted according to the minimum legal carapace size in effect in each LFA (refer to Table 1 for minimum legal size). (gc.ca)
  • Windows and accessible fire escapes need good locking mechanisms. (union.edu)
  • Correctly escaping shell commands on Windows is not a simple matter. (php.net)
  • A simple circle-escaping game. (moddb.com)
  • Background: Treatments for anxiety and related disorders target exaggerated escape/avoidance as a core feature, but current methods fail to improve escape/avoidance habits for many treatment-seeking individuals. (okstate.edu)
  • En Windows, escapeshellarg() elimina en su lugar los signos de porcentaje, remplaza las comillas dobles por espacios y añade comillas dobles al string. (php.net)
  • SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms. (anl.gov)
  • A second fire fighter was knocked down by the force of the explosion and two other fire fighters narrowly escaped injury. (cdc.gov)
  • Treatment-seeking status, then, did not affect cortical processing, but it did moderate context-dependent fear (if individuals with severe depression were excluded) such that treatment-seeking individuals without depression showed exaggerated startle during escape, but not avoidance, preparation. (okstate.edu)
  • These technologies can be used as biomarker discovery tools in human observational studies or to elucidate mechanisms. (who.int)
  • establish mechanisms of action by studying the effects of the same chemicals in experimental animals and on human cells in vitro, allowing for a better prediction of human carcinogenicity and assessment of carcinogenic mechanisms. (who.int)
  • Note that the command is invoked by the shell, so if you need to pass any arguments that come from an untrusted source, you must be careful to strip or escape any special characters that might have a special meaning for the shell. (postgresql.org)
  • As a consequence, the entire command string must be further escaped for cmd.exe. (php.net)
  • If the executed command contains further indirect calls through cmd.exe, each child command must be escaped again for each level of indirection. (php.net)
  • 1979)used an optical density of as an obscuritycriterion cent to burning entry, that some air would leak from the for escape from containing burning furniture. (cdc.gov)
  • Future invetsigations should shed light into the precise mechanism of action of Liproxstatin-1 in ferroptotic signaling. (sciencedaily.com)
  • how smoke would impede their safe escape. (cdc.gov)
  • Smoke cloud irritants play a role in escape from fires. (cdc.gov)
  • The smoke was from wood chips in an electric forpersons who familiar with the escape route. (cdc.gov)
  • It is noted that both were also related to means to get away from the lived situation and/or in the attempt to escape negative thoughts. (bvsalud.org)
  • In addition to ischaemic tissue damage, seen for example in renal failure, stroke or cardiovascular diseases, the mechanism may also play a central role in neurodegenerative diseases and in comorbidities of diabetes mellitus. (sciencedaily.com)
  • I loved David Fincher's The Killer (Netflix 10.27)…a great escape film if I've ever seen and felt one. (hollywood-elsewhere.com)
  • Escape Mechanism is the title of a sound collage project instigated by Minneapolis based artist Jonathan Nelson. (wikipedia.org)
  • Although essentially a studio project, Escape Mechanism experimented briefly (1999 - 2001) with live improvisation. (wikipedia.org)
  • Anti-CRISPR: discovery, mechanism and function. (cdc.gov)
  • Escape Mechanism proudly presents itself as 100% recycled, as every sound found in an Escape Mechanism composition is recycled from a previously recorded source. (wikipedia.org)
  • We found that this enhanced Fn binding leads to a reduction in Ab-mediated phagocytosis, indicating that this constitutes a GAS immune escape mechanism. (lu.se)
  • DNMT3A-mutated AML has high-risk characteristics and shows significantly worse overall survival (OS) ( 2 ), but its mechanism is unclear ( 3 ). (frontiersin.org)
  • o low-overhead escape mechanism for incompressible data. (faqs.org)