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Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. (wikipedia.org)
Nashville, TN - Use of oral erythromycin is associated with a doubling in the risk of sudden cardiac death , and the use of the antibiotic in combination with drugs that are likely to inhibit its metabolism (by inhibiting the CYP3A enzyme) is associated with a fivefold increase in sudden cardiac death, a new study shows. (medscape.com)
Ray et al note that erythromycin is known to prolong the QT interval and that there have been case reports of torsades de pointes occurring in patients receiving both oral and intravenous forms of the antibiotic. (medscape.com)
Results showed that the multivariate-adjusted rate of sudden death from cardiac causes among patients currently using erythromycin was twice as high as that among those who had not used any of the study antibiotic medications. (medscape.com)
The adjusted rate of sudden death from cardiac causes was five times as high among those who concurrently used CYP3A inhibitors and erythromycin than among those who had used neither CYP3A inhibitors nor any of the study antibiotic medications. (medscape.com)
Erythromycin is an wide-spectrum antibiotic that is used in ophthalmic, topical, and systemic treatment of bacterial infections. (fsu.edu)
Erythromycin is a member of the macrolide group of antibiotic medicines. (theonlineclinic.co.uk)
Erythromycin is an antibiotic produced from a strain of Saccharopolyspora erythraea , whereas benzoyl peroxide is an antibacterial and keratolytic agent (causes the break down of keratin). (centerwatch.com)
Erythromycin is an oral macrolide antibiotic that has been in common use since the 1950s. (nih.gov)
Erythromycin (e rith" roe mye' sin) is a semisynthetic macrolide antibiotic used widely for many decades to treat mild-to-moderate bacterial infections caused by sensitive agents. (nih.gov)
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An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Erythromycin stearate (643-22-1). (nih.gov)
Genetic Toxicity Evaluation of Erythromycin Stearate in Salmonella/E.coli Mutagenicity Test or Ames Test. (nih.gov)
Erythromycin is available in multiple formulations (estolate, ethylsuccinate, lactobionate, stearate) in many generic and brand name forms in capsules or tablets of 250 or 500 mg including enteric coated and delayed release forms. (nih.gov)
Using prescription-event monitoring to determine whether erythromycin estolate was a more frequent cause of jaundice than erythromycin stearate or tetracycline 12 208 patients, for whom 5343 doctors had prescribed one of the three drugs, were identified by the Prescription Pricing Authority. (nih.gov)
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Erythromycin 500mg dosage for adults how many days The specific dose and duration of erythromycin 500mg for adults will depend on the condition being treated and the recommendations of your healthcare professional. (erythromycinlab.com)
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Erythromycin estolate has been associated with reversible hepatotoxicity in pregnant women in the form of elevated serum glutamic-oxaloacetic transaminase and is not recommended during pregnancy. (wikipedia.org)
Initially, liver injury was thought to be more common with, or perhaps limited to, erythromycin estolate. (nih.gov)
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Erythromycin was first isolated in 1952 from the bacteria Saccharopolyspora erythraea. (wikipedia.org)
Erythromycin can be used to treat bacteria responsible for causing infections of the skin and upper respiratory tract, including Streptococcus, Staphylococcus, Haemophilus and Corynebacterium genera. (wikipedia.org)
The combination of erythromycin and sulfisoxazole (a sulfa drug) is used to treat certain ear infections caused by bacteria. (nih.gov)
Erythromycin acts on susceptible strains of bacteria, inhibiting their growth and preventing them from reproducing. (theonlineclinic.co.uk)
Benzamycin is a combination of two active ingredients, benzoyl peroxide and erythromycin, which has proven effective in stopping acne-causing bacteria and reducing acne infection. (centerwatch.com)
To reduce the development of drug-resistant bacteria and maintain the effectiveness of erythromycin and other antibacterial drugs, erythromycin should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. (nih.gov)
At least 90 percent of the following bacteria exhibit an in vitro minimum inhibitory concentration (MIC) less than or equal to the susceptible breakpoint for erythromycin against isolates of similar genus or organism group. (nih.gov)
However, the efficacy of erythromycin in treating clinical infections caused by these bacteria has not been established in adequate and well-controlled clinical trials. (nih.gov)
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Because this interference applies only to bacteria and not with the way mammals make proteins, erythromycin can be used to treat bacterial infections. (vin.com)
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Lower doses of erythromycin stop bacteria from reproducing but technically do not kill them. (vin.com)
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Erythromycin is commonly used as a second-line agent when penicillin, tetracyclines or metronidazole are contraindicated. (nih.gov)
Strains with an erythromycin MIC ≥0.5 μg/mL and penicillin MIC ≥0.12 μg/mL were defined as erythromycin-nonsusceptible and penicillin-nonsusceptible S. pneumoniae , respectively ( 6 ). (cdc.gov)
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Erythromycin lactobionate for injection, USP is a soluble salt of erythromycin suitable for intravenous administration. (nih.gov)
Erythromycin lactobionate is chemically known as erythromycin mono (4-0-β-Dgalactopyranosyl-D-gluconate) (salt). (nih.gov)
Intravenous infusion of 500 mg of erythromycin lactobionate at a constant rate over 1 hour in fasting adults produced a mean serum erythromycin level of approximately 7 mcg/mL at 20 minutes, 10 mcg/mL at 1 hour, 2.6 mcg/mL at 2.5 hours, and 1 mcg/mL at 6 hours. (nih.gov)
Erythromycin lactobionate for injection, USP is indicated in the treatment of infections caused by susceptible strains of the designated organisms in the diseases listed below when oral administration is not possible or when the severity of the infection requires immediate high serum levels of erythromycin. (nih.gov)
Objective -To identify and characterize motilin receptors in equine duodenum, jejunum, cecum, and large colon and to determine whether erythromycin lactobionate competes with porcine motilin for binding to these receptors. (avma.org)
Displacement studies were used to investigate competition between 125 I-labeled synthetic porcine motilin and erythromycin lactobionate for binding to motilin receptors in various segments of bowel. (avma.org)
Erythromycin lactobionate displacement of 125 I-labeled porcine motilin from the equine motilin receptor did not differ significantly among various segments of bowel. (avma.org)
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Many other medications may also interact with erythromycin, so tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
What drugs interact with erythromycin? (onteenstoday.com)
Many drugs can interact with erythromycin. (grinh.com)

Intravenous erythromycin may also be used in endoscopy to help clear stomach contents. (wikipedia.org)
But they point out that the magnitude of the risk of ventricular tachyarrhythmia has not been quantified in population-based studies, and any studies that have been done have focused on the intravenous use of the drug, even though in clinical practice erythromycin is usually administered orally. (medscape.com)
For this reason, intravenous erythromycin has been proposed as a pre-endoscopy aid in visualization and treatment of upper GI bleeding. (thennt.com)

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Take erythromycin exactly as directed. (medlineplus.gov)
Continue to take erythromycin even if you feel well. (medlineplus.gov)
tell your doctor if you are taking astemizole (Hismanal) (not available in the U.S.), cisapride (Propulsid) (not available in the U.S.), dihydroergotamine (DHE 45, Migranal), ergotamine (Ergomar, in Cafergot, in Migergot), pimozide (Orap), or terfenadine (Seldane) (not available in the U.S.). Your doctor will probably tell you not to take erythromycin if you are taking one or more of these medications. (medlineplus.gov)
If you forget to take Erythromycin at the scheduled time, then take it as soon as you remember, but do not take more than you have been told. (theonlineclinic.co.uk)
Take erythromycin exactly as it was prescribed for you. (grinh.com)
If you have liver disease or myasthenia gravis, you may need a dose adjustment or special tests to safely take erythromycin. (grinh.com)
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To try to quantify the association between oral erythromycin and the risk of sudden death from cardiac causes, the researchers studied a previously identified Tennessee Medicaid cohort that included 1249943 person-years of follow-up and 1476 cases of confirmed sudden death from cardiac causes. (medscape.com)
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Erythromycin is used to prevent or treat individuals with bacterial infections. (theonlineclinic.co.uk)

More than one in five invasive GAS infections are caused by throat--imagine if it were erythromycin- and clindamycin-resistant strains, limiting the untreatable. (cdc.gov)
5% to erythromycin and other macrolides, and to clindamycin complicates the treatment of both strep throat and severe c ent of R er invasive infections. (cdc.gov)
Antagonism has been demonstrated in vitro between erythromycin and clindamycin, lincomycin and chloramphenicol. (nih.gov)

Erythromycin (500 mg qid) was given from 7 days before through 4 days after the second atorvastatin dose. (nih.gov)
Additionally, Erythromycin can interact with other drugs, so your dose of Erythromycin may require modification. (theonlineclinic.co.uk)
Two women were given a single dose of 500 mg erythromycin (salt unspecified) orally, and milk levels were measured at 2 and 6 hours after the dose. (nih.gov)
Average erythromycin milk levels at 2, 4, and 6 hours after the dose were 1, 1.2 and 1.1 mg/L, respectively. (nih.gov)
Fifteen women who were 1 month postpartum were given a single 500 mg dose of erythromycin intravenously. (nih.gov)
In addition, there was considerable variation of the erythromycin dose among the included trials, though studies have suggested an effect with as little as 70 mg of erythromycin, 3 well below even the lowest doses used in these trials. (thennt.com)

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There are several other reasons a baby might develop eye discharge in the first few weeks of life, including a rare allergic reaction to erythromycin. (healthychildren.org)

Modifications of erythromycin have been developed with a wider range of activity and less likelihood for resistance (azithromycin, clarithromycin, telithromycin). (nih.gov)

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After increasing from 1995 to 1999, invasive erythromycin-nonsusceptible Streptococcus pneumoniae rates per 100,000 decreased 53.6% in children from Baltimore, Maryland (US), from 1999 to 2001, which was partially attributed to strains related to the mef E-carrying England 14 -9 clone. (cdc.gov)
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Possible mechanisms for this interaction include erythromycin inhibition of first-pass conversion of atorvastatin to inactive metabolites and erythromycin inhibition of P-glycoprotein-mediated intestinal or biliary secretion. (nih.gov)
Erythromycin acts by inhibition of protein synthesis by binding 50 S ribosomal subunits of susceptible organisms. (nih.gov)
To evaluate the degree of drug-drug interaction concerning metabolic inhibition in the liver quantitatively, we tried to predict the plasma concentration increasing ratio (R) of midazolam (MDZ) by erythromycin (EM), diltiazem (DLZ), or verapamil (VER) in rats. (aspetjournals.org)

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Because of the low levels of erythromycin in breastmilk and safe administration directly to infants, it is acceptable in nursing mothers. (nih.gov)
Other drugs that can increase blood levels of erythromycin include omeprazone (an antacid) and the azole class of antifungal drugs ( ketoconazole , itraconazole , and fluconazole ). (vin.com)

Exposure to erythromycin (especially long courses at antimicrobial doses, and also through breastfeeding) has been linked to an increased probability of pyloric stenosis in young infants. (wikipedia.org)
Erythromycin used for feeding intolerance in young infants has not been associated with hypertrophic pyloric stenosis. (wikipedia.org)
Only 2 of the 55 infants exposed to a macrolide were exposed to erythromycin. (nih.gov)
In one telephone follow-up study, mothers reported diarrhea 2 infants and irritability in 2 infants out of 17 infants whose mothers were taking erythromycin during breastfeeding. (nih.gov)
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There are some medicines that don't mix well with erythromycin. (onteenstoday.com)
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Cases of invasive pneumococcal disease with an erythromycin MIC ≥0.5 μg/mL isolated from January 1,1995, to December 31, 2001, were included. (cdc.gov)

Erythromycin is also used sometimes used to prevent heart infection in people having dental or other procedures. (medlineplus.gov)
Penicillins are more effective than erythromycin in preventing neonatal GBS infection in women with PPROM who were active GBS carriers. (onteenstoday.com)
Amoxicillin is more effective than erythromycin for the treatment of antenatal Chlamydia trachomatis infection and has fewer gastrointestinal side-effects, leading to better compliance. (onteenstoday.com)
Erythromycin is one of the few drugs that is able to penetrate the prostate gland and treat infection there, while most other antibiotics are stopped by the blood-prostate barrier. (vin.com)

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