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  • Furthermore
  • Furthermore, the recombinant VP1u competed with B19V uptake into permissive cells, thus excluding a significant alternative uptake mechanism by other receptors. (mdpi.com)
  • populations
  • The one with higher affinity was present mainly in erythroid cells and showed an association constant similar to that observed in reticulocyte populations. (ovid.com)
  • regulation
  • However, erythroid and nonerythroid cells exhibit distinct differences in the heme biosynthetic pathway regulation. (hindawi.com)
  • To address this question we have established a human inducible erythroid cell system, which recapitulate DICE-dependent translational regulation in vitro and in vivo. (uni-wuerzburg.de)
  • This is the first report of an EF1-like activity in non-erythroid cells and indicates that this factor may play a role in the regulation of genes expressed in such cells. (soton.ac.uk)
  • assay
  • Sato, Hiroyuki 1999-12-01 00:00:00 A human parvovirus B19 (B19) infectivity assay was developed using the erythroid cell line, KU812Ep6. (deepdyve.com)
  • This KU812Ep6 infectivity assay had a 10 3 -10 4.5 higher sensitivity than the colony forming unit-erythroid (CFU-e) injury assay. (deepdyve.com)
  • B19V DNA increment was in accordance with the percentage of cells positive to flow-FISH assay 41.4% at day 9, 1.1% at day 18. (duhnnae.com)
  • Disorders
  • Our study supports ATP2B4 as a potential target for modulating rbc hydration in erythroid disorders and malaria infection. (jci.org)
  • biosynthesis
  • Ferrochelatase, which catalyses the last step in haem biosynthesis, i.e. the insertion of Fe(II) into protophorphyrin IX, is present in all cells, but is particularly abundant in erythroid cells during haemoglobinization. (biochemj.org)
  • receptor
  • Taken together, these findings suggest that the VP1u binds to a yet-unknown erythroid-specific cellular receptor and thus restricts the virus entry to permissive cells. (mdpi.com)
  • CFU-GEMM express also CD38 but do not express the α subunit of the interleukin-3 (IL-3) receptor, which is acquired during the transition of these cells to BFU-E, CFU-GM, and CD45RA [ 7 , 8 ], which is specifically expressed by BFU-E [ 5 , 6 ]. (hindawi.com)
  • CD34
  • Cells were stained with 50 μg/mL propidium iodide (PI, Sigma, St Louis, MO) and analyzed by FACscan flow cytometry (Becton Dickinson) for cell cycle status, stained with PE- or FITC-conjugated anti-CD34, anti-CD71, or anti-GPA antibodies and analyzed for cell surface antigens. (bloodjournal.org)
  • soluble
  • After various periods of [35S]methionine incorporation, cells were lysed in a Triton X-100-containing buffer and separated into a soluble and an insoluble (cytoskeletal) fraction. (caltech.edu)
  • tissues
  • Using mouse ferrochelatase cDNA as a probe two ferrochelatase transcripts, having lengths of 2.9 kb and 2.2 kb, were found in extracts of mouse liver, kidney, brain, muscle and spleen, the 2.9 kb transcript being more abundant in the non-erythroid tissues and the 2.2 kb transcript more predominant in spleen. (biochemj.org)
  • These flexible cells take up oxygen from the lungs and deliver it to the tissues that use it to perform metabolic reactions necessary for our survival. (atlasofscience.org)
  • Stem Cell
  • We previously reported that polyploid giant cancer cells (PGCCs) induced by cobalt chloride (CoCl 2 ) exhibit cancer stem cell properties. (jcancer.org)
  • PGCCs from LoVo and HCT116 treated by CoCl 2 exhibited cancer stem cell properties. (jcancer.org)
  • Although this metabolic pathway is required for stem cell maintenance, other pathways also play critical roles. (ovid.com)