• Although erythrocytes are flexible (which permits them to squeeze through capillaries), they typically have a distinctive biconcave shape that helps maximize surface area to facilitate the exchange of gases. (giantmicrobes.com)
  • Shape change of erythrocytes under applied forces (i.e., shear forces in blood flow) is reversible and the biconcave-discoid shape, which is normal for most mammals, is maintained after the removal of the deforming forces. (wikipedia.org)
  • Arylamine N-acetyltransferase type 1 is expressed in erythrocytes and leucocytes and the activity in erythrocytes is shown to contribute approximately 99% of the activity of arylamine N-acetyltransferase type 1 in blood cells. (nih.gov)
  • These findings suggest that primate erythrocytes intercept large complement-fixing IC in the circulation causing the IC to adhere to the erythrocyte until th e IC-bearing erythrocyte traverses liver where the IC is deposited, and the erythrocyte is returned to the circulation. (jci.org)
  • In this thesis, healthy erythrocytes are shown to adhere to endothelial cells, provided that endothelial cells are activated and erythrocytes are exposed to a stimulus that induces a calcium influx. (uva.nl)
  • Furthermore, it is described that erythrocytes adhere to ultra large von Willebrand factor strings that are released from activated endothelial cells or to von Willebrand factor that is immobilized on a surface. (uva.nl)
  • The NAD glycohydrolase (NADase) was solubilized from intact erythrocytes with bacterial phosphatidylinositol-specific phospholipase C and purified to homogeneity by affinity chromatography on Cibacron blue-agarose. (nih.gov)
  • Chapman BE, Beilharz GR, York MJ, Kuchel PW (1982) Endogenous phospholipase and choline release in human erythrocytes: A study using 1 H NMR spectroscopy. (springer.com)
  • The adhesion of erythrocytes to von Willebrand factor increases significantly when the wall shear stress approaches stasis. (uva.nl)
  • Free choline (more than 10-fold) and phosphorylcholine (2-fold) were significantly increased in erythrocytes of lithium-treated patients as compared to the healthy untreated controls. (springer.com)
  • It also affects the microcirculatory blood flow significantly, where erythrocytes are forced to pass through blood vessels with diameters smaller than their size. (wikipedia.org)
  • Each blood sample was then centrifuged on percoll to separate IC bound to erythrocytes from IC in plasma or bound to buffy coat cells. (jci.org)
  • This resulted in an "erythrocyte fraction" beneath the percoll that contained the IC bound to erythrocytes, and a "plasma/buffy coat fraction" above the percoll that contained the IC in plasma and IC bound to buffy coat cells. (jci.org)
  • In 17 lithium-treated patients with manic-depressive disorders and 11 healthy subjects the concentrations of choline, phosphorylcholine, cytidyldiphosphate choline, lipid bound choline, and glycerophosphorylcholine were measured in plasma and erythrocytes. (springer.com)
  • In contrast, IC on erythrocytes did not deposit in kidney. (jci.org)
  • However, this thesis describes that erythrocytes can bind to von Willebrand factor and this interaction may contribute to the stabilization and propagation of a venous thrombus. (uva.nl)
  • Analysis of these data showed that the majority of the IC infused into the circulation rapidly became bound to erythrocytes. (jci.org)
  • However, by 5 min after beginning the IC infusion, most of this IC load had been removed from the erythrocytes as they traversed the liver. (jci.org)
  • Amino acid composition of the rabbit erythrocyte enzyme differed from that of NADases of other species, and the purified NADase contains 8% carbohydrate and a stoichiometric amount of inositol. (nih.gov)
  • Erythrocyte comes from the Greek words: Erythros= red, Cyte= cell. (giantmicrobes.com)
  • In other words, erythrocytes behave like elastic bodies, while they also resist to shape change under deforming forces. (wikipedia.org)
  • The oxidative changes in chondrocytes of OA patients are reflected in erythrocytes as evidenced by increased LP. (thefreedictionary.com)
  • Arylamine N-acetyltransferase in erythrocytes of cystic fibrosis patients. (nih.gov)
  • Arylamine N-acetyltransferase type 1 activity in erythrocytes from 16 adult cystic fibrosis patients and 19 age-matched controls were compared. (nih.gov)
  • The increased clearance of sulphamethoxazole in cystic fibrosis patients appears unlikely to be due to erythrocyte arylamine N-acetyltransferase type 1 activity or to inheritance of alleles at either the NAT1 or NAT2 loci. (nih.gov)
  • This study was undertaken to determine whether the binding of IC to erythrocytes in vivo might play a role in the removal of IC from the circulation. (jci.org)
  • The thesis is concluded by a summary and discussion about the erythrocyte-von Willebrand factor interaction and its implications for venous thrombosis. (uva.nl)
  • This primate erythrocyte-IC-clearing mechanism may be important in the protection against diseases mediated by deposition of circulating IC. (jci.org)
  • Erythrocyte deformability is an important determinant of blood viscosity, hence blood flow resistance in the vascular system. (wikipedia.org)
  • The heterozygous NAT1 individual is a cystic fibrosis patient with a low level of erythrocyte arylamine N-acetyltransferase type 1 activity. (nih.gov)
  • There was no correlation between erythrocyte arylamine N-acetyltransferase-1 activity and NAT2 alleles present in either the cystic fibrosis or control groups. (nih.gov)