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  • morbidity and morta
  • In this already critical situation, it is important to remember that transfusion reactions themselves carry their own morbidity and mortality risk. (blogspot.com)
  • New frontiers in transfusion biology: identification and significance of mediators of morbidity and mortality in stored red blood cells. (biomedsearch.com)
  • Each unit of transfused blood has approximately 250 mg of iron, with each successive transfusion, patients receiving chronic transfusion therapy accumulate iron in various tissues in the body as the body has no way to excrete the excess, this is a cause of increased morbidity and mortality. (wikipedia.org)
  • adult
  • 1-3 Important variability in intraoperative bleeding and erythrocyte requirements has been reported in adult patients undergoing major spine surgery. (asahq.org)
  • For this purpose, the Predictive Model of Transfusion in Spine Surgery (PMTSS), based on preoperative characteristics, was generated to determine the individual probability of erythrocyte transfusion in adult patients undergoing spine surgery. (asahq.org)
  • Two isoforms are known and the gene is expressed in a wide variety of tissues including kidney, thymus, stomach, breast, adult liver and erythrocyte. (wikipedia.org)
  • hemolytic
  • The onset is usually more delayed than hemolytic fever, occurring 1 to 6 hours after the transfusion begins. (blogspot.com)
  • In summary, if your patient develops dyspnea, chest pain, fever or hypotension while receiving a transfusion, you must stop the transfusion immediately, resuscitate the patient, obtain a chest X-ray, and send direct Coombs' test and urinalysis to evaluate for a hemolytic process. (blogspot.com)
  • risk
  • In children prophylactic chronic red blood cell (RBC) transfusion therapy has been shown to be efficacious to a certain extent in reducing the risk of first stroke or silent stroke when transcranial Doppler (TCD) ultrasonography shows abnormal increased cerebral blood flow velocities. (wikipedia.org)
  • Plasma
  • It arises from a deficiency in the enzyme ferrochelatase, leading to abnormally high levels of protoporphyrin in the erythrocytes, plasma, skin and liver. (wikipedia.org)
  • Since FECH deficiency is associated with increased concentrations of protoporphyrin in erythrocytes, plasma, skin and liver, retention of protoporphyrin in skin predisposes to acute photosensitivity. (wikipedia.org)
  • As a result of absorption of ultraviolet light (that is, wavelengths less than 400 nm) by protoporphyrin in plasma and erythrocytes when blood circulates through the dermal vessels, free radicals are formed, erythrocytes become unstable and injury to the skin is induced. (wikipedia.org)
  • patient
  • 3 The accuracy of the MSBOS in predicting transfusion requirements may also be improved by accounting for patient-specific variables such as preoperative hematocrit and the lowest tolerable hematocrit. (asahq.org)
  • In October 1915, Robertson performed his first wartime transfusion with a syringe to a patient suffering from multiple shrapnel wounds. (wikipedia.org)