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  • glycophorin
  • These have been named glycophorin A, B, C and D in order of the quantity present in the membrane - glycophorin A being the most and glycophorin D the least common. (wikipedia.org)
  • localization
  • At present, the family consists of six sub-families comprising a total of 13 separate isoforms that differ in their mode of activation, expression levels, catalytic regulation, cellular localization, membrane binding avidity and tissue distribution. (wikipedia.org)
  • ankyrin
  • 12 ⇓ - 14 Manual rupture of this bridge by addition of competing fragments of either band 3 or ankyrin, or by addition of competing monoclonal antibodies, or mutation of the ankyrin binding site on band 3 induces spontaneous membrane vesiculation and fragmentation. (bloodjournal.org)
  • 17 ⇓ ⇓ - 20 Taken together, these data support the importance of the ankyrin-spectrin bridge in maintaining membrane integrity. (bloodjournal.org)
  • Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of band 3 with ankyrin. (wikipedia.org)
  • antigens
  • The expression frequencies of 16 erythrocyte antigens among patients with Type II congenital smell loss were determined and compared to those of a large control group. (nih.gov)
  • gene
  • Two isoforms are known and the gene is expressed in a wide variety of tissues including kidney, thymus, stomach, breast, adult liver and erythrocyte. (wikipedia.org)
  • elliptocytosis
  • We have examined 20 different individuals from 10 spherocytosis kindreds and 2 elliptocytosis kindreds to determine the effects of different levels of spectrin deficiency on the viscoelastic properties of the erythrocyte membrane. (jci.org)
  • Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. (wikipedia.org)
  • Fatty
  • Fatty acid composition of erythrocyte phosphatidylcholines was determined by high-resolution capillary gas chromatography in Spanish (n = 120), German (n = 78) and Hungarian (n = 43) expectant women at the 20th week of gestation. (springer.com)
  • A portion of the blood sample (500 µL) will be sent to the laboratory of Lipinutragen (spin-off of CNR- National Research Center Bologna, Italy) where an erythrocyte membrane lipidomic analysis will be performed for the characterization of membrane phospholipids, in order to determinate the different lipid components (saturated fatty acids, monounsaturated and polyunsaturated, trans fatty acids), each one characterized by a different oxidative reactivity. (clinicaltrials.gov)
  • reactivity
  • Lipid peroxidation was assessed in fresh, untreated erythrocytes by quantitating thiobarbituric acid reactivity and an adduct of phospholipids and malonyldialdehyde (MDA), an end product of lipid peroxidation, with thin-layer chromatography of lipid extract of diabetic erythrocytes. (diabetesjournals.org)
  • surface
  • These findings describe the presence of a previously unrevealed genetic tendency among patients with Type II congenital smell loss related to erythrocyte surface antigen expression. (nih.gov)
  • Results show correlation between the fractional reduction in shear modulus and the fractional reduction in spectrin content (determined by spectrin radioimmunoassay) and spectrin density (determined by the ratios of spectrin to band 3 on electrophoresis gels) suggesting that membrane shear elasticity is directly proportional to the surface density of spectrin on the membrane (P less than 0.001). (jci.org)
  • mechanisms
  • Hyperactive platelets are involved in the development of atherosclerosis by different mechanisms such as membrane shedding, growth factor secretion and expression of several adhesive factors. (wikipedia.org)