AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation Science
Lichen PlanusLichen Planus, OralLichensLichenoid EruptionsAcitretinVulvar Lichen SclerosusMouth MucosaLichen Sclerosus et AtrophicusKeratolytic AgentsTongue DiseasesHyperpigmentationClobetasolLeukoplakia, OralTolonium ChlorideMouth DiseasesKeratosisFluocortoloneVulvar DiseasesMouth NeoplasmsGingivitis, Necrotizing UlcerativeLip DiseasesLichen NitidusHand DermatosesStomatitis, AphthousPUVA TherapyHematoxylinNeurodermatitisGingival DiseasesMelanosisPhototherapyLeukoplakiaSkin DiseasesDermatitisEosine Yellowish-(YS)AnetodermaPrecancerous ConditionsBurning Mouth SyndromeAdministration, TopicalPhotosensitivity DisordersPeriodic Acid-Schiff ReactionFoot DermatosesStomatitisHair RemovalFlatfootGingivitisCalendulaPemphigoid, Benign Mucous MembraneGranulomatosis, OrofacialEncyclopedias as Topic
LesionsSclerosusElevated in oral lichenSimplex chronicusAtrophicCutaneous lichen planusHypertrophicInflammatoryRuber planusPemphigus vulgarisMucous membranesUlcerativeDiagnosisEsophagitisSquamousSclerosisVulvaClinicalPapulesScalpMucosalAffectsDermatitisHepatitisInfiltrateReticularGenitalDermatologicEruptionsEczemaOccurPatientsSymptomsTreatmentReactionRelatively commonDiagnosePrevalenceOccursMalignantMarkingsRarely
Lesions19
  • In long standing lesions, especially in erosive and hypertrophic variants, squamous cell carcinoma may occur. (thedoctorsdoctor.com)
  • Therefore, early in the formation of oral lichen planus lesions, CD8 + T cells may recognize an antigen associated with the major histocompatibility complex (MHC) class I on keratinocytes. (medscape.com)
  • Oral lichen planus lesions contain increased levels of the cytokine tumor necrosis factor (TNF)-alpha. (medscape.com)
  • The role of autoimmunity in the pathogenesis is supported by many autoimmune features of oral lichen planus, including its chronicity, onset in adults, predilection for females, association with other autoimmune diseases, occasional tissue-type associations, depressed immune-suppressor activity in patients with oral lichen planus, and the presence of autocytotoxic T-cell clones in lichen planus lesions. (medscape.com)
  • Reported associations between oral lichen planus and systemic diseases may be coincidental, because (1) oral lichen planus is relatively common, (2) oral lichen planus occurs predominantly in older adults, and (3) many drugs used in the treatment of systemic diseases trigger the development of oral lichenoid lesions as an adverse effect. (medscape.com)
  • In 1982, Pelisse and colleagues reintroduced a similar variant of mucosal LP as the vulvovaginal-gingival syndrome with erosive lesions involving the oral and vulvovaginal mucosa [ 10 ]. (hindawi.com)
  • The increased expression of COX-2 has been reported in pre-cancerous lesions, in several forms of cancer, including squamous cell carcinoma and in OLP [ 7 ]. (ecancer.org)
  • Lichen planus is a recurrent, pruritic, inflammatory eruption characterized by small, discrete, polygonal, flat-topped, violaceous papules that may coalesce into rough scaly plaques, often accompanied by oral and/or genital lesions. (msdmanuals.com)
  • This image shows vesiculobullous lesions (some ruptured) resulting from lichen planus. (msdmanuals.com)
  • Although rarely reported in childhood, lichen planus should be considered in a differential diagnosis of hyperkeratotic, reticular, and ulcerative lesions of the oral mucosa in children. (9lib.co)
  • The oral lesions are more pleomorphic than those of their cutaneous forms and subtypes are categorized as reticular, papular, plaque-like, atrophic, erosive, and bullous [3]. (9lib.co)
  • This paper also reviews ulcerative oral lichen planus in children and empha- sizes its diagnosis from other oral white and red lesions in children. (9lib.co)
  • The differential diagnosis was lichen planus and lichenoid lesions. (9lib.co)
  • Lichen planus is a chronic inflammatory disease of unknown origin, which most commonly affects individuals between 30-60 years of age and is characterized by different types of lesions involving the skin and mucosa . (amboss.com)
  • Lichen planus is clinically diagnosed based on the presence of typical skin lesions. (amboss.com)
  • Manifests with diffuse lesions that closely resemble lichen planus but are not histologically identical. (amboss.com)
  • During SLE, the involvement of the oral mucosa may manifest as erosions or atrophic lesions with whitish striations, which may mimic lichen planus. (odermatol.com)
  • Erosive lichen planus Lesions are painful , but mostly when eating, whereas erythematous candidiasis may be associated with constant burning pain . (symptoma.com)
  • The clinical diagnosis of SCC on the dorsum of the tongue is difficult because it may be mimicked by a wide variety of benign and premalignant lesions, including granular cell myoblastoma, erosive lichen planus, medial rhomboid glossitis, and amyloidosis. (psu.edu)
Sclerosus10
  • Lichen sclerosus is an unusual, but long-term pores and skin illness that can affect each male and female patients. (imgsin.org)
  • Introduction We have a series of posts looking at lichen sclerosus and other vulvovaginal conditions. (lssupportnetwork.org)
  • For example, we have lichen sclerosus and menopause and lichen sclerosus, and lichen simplex chronicus. (lssupportnetwork.org)
  • We do these posts to promote vulvovaginal education and because some folks have lichen sclerosus and other conditions. (lssupportnetwork.org)
  • In this post, we continue this series and will look at lichen planus and lichen sclerosus. (lssupportnetwork.org)
  • If you are curious about the difference between lichen sclerosus and lichen planus, want to know what to look out for, and wonder if you can have both lichen sclerosus and lichen planus, this post is for you! (lssupportnetwork.org)
  • I draw on the medical literature to share what you need to know about lichen planus and lichen sclerosus. (lssupportnetwork.org)
  • Lichen Sclerosus Support Network is a 501(c)(3) nonprofit organization (Tax ID #87-2172854). (lssupportnetwork.org)
  • Lichen simplex chronicus may occur because of itching associated with another skin disease such as lichen sclerosus, or may develop as de novo itching. (vulvovaginaldisorders.org)
  • Because eczematous conditions can be caused by instigators such as candida , contact with allergens or irritants, and lichen simplex chronicus can also be stimulated by skin response to underlying dermatoses such as lichen sclerosus, careful detective work includes yeast cultures and, if the diagnosis is not clear, biopsy. (vulvovaginaldisorders.org)
Elevated in oral lichen1
Simplex chronicus6
  • Another term clear to dermatologists but unknown to lay people is the term lichen simplex chronicus (LSC). (vulvovaginaldisorders.org)
  • Lichen simplex chronicus is closely linked with itching and may occur anywhere on the skin, including on the vulva. (vulvovaginaldisorders.org)
  • See Lichen simplex chronicus in the Atlas). (vulvovaginaldisorders.org)
  • A semantic assumption is made by many dermatologists that lichen simplex chronicus is the descriptive term that encompasses localized eczematous conditions in the vulva, atopic dermatitis the term that encompasses generalized conditions, and that the clinician's job is to come to understand what might have precipitated the condition and treat both the LSC and the originating condition. (vulvovaginaldisorders.org)
  • The etiology of eczematous dermatitis, also known as lichen simplex chronicus when it appears on the vulva, is unknown, but because it is highly correlated with itching, it can be said that pruritus is the etiology of the condition. (vulvovaginaldisorders.org)
  • Dr. Funaro emphasized the important concept that in the case of lichen simplex chronicus (LSC), it is important to reexamine the patient after treatment, because LSC can mask the presence of underlying pruritic vulvar disease such as LS et A or psoriasis . (medscape.com)
Atrophic5
  • Of possible significance, elevated concentrations of interleukin-6 (IL-6) and neopterin in saliva and serum of patients with the erosive-atrophic form of oral lichen planus suggest they may be involved in the etiology of this disease variation. (medscape.com)
  • This retrospective study was carried out from 1387 to 1398 on 40 OLP samples (24non-erosive-atrophic and 16 erosive-atrophic forms) in the Oral Pathology Department of Mashhad Dental School. (magiran.com)
  • Oral lichen planus (OLP) is a chronic inflammatory disease that can be painful, mainly in the atrophic and erosive forms. (ncl.ac.uk)
  • Major forms of oral candidiasis are pseudomembranous and atrophic form, but chronic hyperplastic candidiasis (CHC) is rarely seen. (symptoma.com)
  • Scheme on natural course and progression of Helicobacter pylori gastritis from a non-atrophic form to gastric malignancy (sc. (capsulehealth.one)
Cutaneous lichen planus2
  • Cutaneous lichen planus (CLP) most commonly involves the flexor surfaces of the extremities and presents as small itchy violaceous Papules in middle-aged adults. (hindawi.com)
  • Recent data suggest that OLR present a greater percentage of malignant transformation than OLP and, although the association between cancer and OLP has been documented in scientific reports, there is no association between squamous cell carcinoma and cutaneous lichen planus [ 4 - 6 ]. (ecancer.org)
Hypertrophic1
  • The burden of the disease is higher in some variants including hypertrophic LP and erosive oral LP, which may have a more chronic pattern. (hindawi.com)
Inflammatory9
  • Lichen planus is a pruritic inflammatory dermatosis of unknown origin. (thedoctorsdoctor.com)
  • Sir, Lichen planus (LP) is an immunologically mediated inflammatory disorder involving skin, hair, nail, and mucous membrane. (ijdd.in)
  • Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. (hindawi.com)
  • Lichen planus (LP) is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. (hindawi.com)
  • LP (Greek "Leichen" = tree moss, Latin "planus" = flat, even) [ 2 ] was first explained in 1869 by Dr. Wilson as an inflammatory disorder of the stratified squamous epithelia with an unknown etiology. (hindawi.com)
  • Oral lichen planus and lichenoid reactions are autoimmune type inflammatory conditions of the oral mucosa with similar clinical and histological characteristics. (ecancer.org)
  • Lichen planus (LP) is a chronic inflammatory mucocutaneous condition which is relatively common in adults but rarely affects children. (9lib.co)
  • Lichen planus (LP) is an autoimmune, chronic, inflammatory disease that affects mucosal and cutaneous tissues. (9lib.co)
  • Lichen planus and lichen sclerosis are inflammatory, autoimmune skin conditions that can occur anywhere in the body but most often on the vulva. (drbrighten.com)
Ruber planus1
  • It was originally named "lichen ruber planus" and "lichen psoriasis" [ 5 ]. (hindawi.com)
Pemphigus vulgaris2
  • Erosive lichen planus, mucous membrane pemphigoid, pemphigus vulgaris, erythema exsudativum multiforme and lupus erythematosus. (wikipedia.org)
  • This results in dental plaque disease must embody pemphigus vulgaris and erosive lichen accumulation, which in turn superimposes an extra, planus amongst others (Table 1-2) medicine 5443 buy oxybutynin with paypal . (suzumgerecleri.com)
Mucous membranes1
Ulcerative2
  • Ulcerative oral lichen planus on the dorsum of the tongue. (medscape.com)
  • An REU (reticular/hyperkeratotic, erosive/erythematous, ulcerative) scoring system was adopted and compared between the OLP patients with and without hematinic deficiencies. (biomedcentral.com)
Diagnosis1
  • On the basis of clinico-histopathological findings, the final diagnosis of erosive vulvovaginal LP was confirmed. (ijdd.in)
Esophagitis2
  • It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid). (fr.nf)
  • If untreated, GERD can result in Erosive Esophagitis, a more serious consequence that can cause ulcers, bleeding, and constriction of the food pipe. (askdrshah.com)
Squamous1
Sclerosis2
  • Lichen sclerosis and lichen planus are often underdiagnosed and undertreated. (drbrighten.com)
  • In adult women, the top 5 causes of genital ulceration are herpes simplex virus (HSV), erosive candidiasis , erosive lichen planus (LP), lichen sclerosis et atrophicus (LS et A), and aphthosis. (medscape.com)
Vulva1
  • Erosive LP of vulva and autoimmune diseases has temporal association. (ijdd.in)
Clinical4
  • Oral lichen planus (OLP) is a chronic mucocutaneous disorder that presents in a wide range of clinical forms, such as unilateral or bilateral white striations, papules, or plaques on the buccal mucosa, labial mucosa, tongue, and gingiva. (medscape.com)
  • Oral lichen planus treatment offers favorable clinical results over time due to its widespread prevalence. (magiran.com)
  • Objective: To describe the main clinical features, histological aspects and treatment of leukoplakia, erythroplakia, actinic cheilitis and oral lichen planus. (bvsalud.org)
  • The authors certify that they have obtained all appropriate patient consent forms, in which the patients gave their consent for images and other clinical information to be included in the journal. (odermatol.com)
Papules4
Scalp2
  • If the scalp is affected, patchy scarring alopecia (lichen planopilaris) may occur. (msdmanuals.com)
  • Lichen planus can affect the skin , mucosa , scalp, genitalia, and nails , and manifests with varying symptoms depending on the subtype of the disease. (amboss.com)
Mucosal1
Affects1
Dermatitis1
Hepatitis4
Infiltrate2
  • The dense subepithelial mononuclear infiltrate in oral lichen planus is composed of T cells and macrophages, and there are increased numbers of intraepithelial T cells. (medscape.com)
  • OLR tend to be unilateral and erosive, with a slightly more diffuse lymphocytic infiltrate with increased eosinophils, plasmocytes, and cytoid bodies than OLP, although it is common to find similar histological characteristics in both entities [ 1 - 3 ]. (ecancer.org)
Reticular2
  • Reticular oral lichen planus on the buccal mucosa on the left side. (medscape.com)
  • o líquen plano oral tem uma variedade de apresentações clínicas, sendo a forma reticular a mais comum. (bvsalud.org)
Genital2
  • [1] Here, we are sharing our experience of isolated genital erosive LP treated with metronidazole 500 mg twice daily for 3 months. (ijdd.in)
  • Fordyce spots on the penis take the form of small (around 1-2mm in diameter) yellow-white spots within the genital area - on the shaft of the penis and the testicles, and typically beneath the foreskin, if present. (imgsin.org)
Dermatologic1
  • Dermatologic conditions cause about 75% of cases of desquamative gingivitis, and over 95% of the dermatologic cases are accounted for by either oral lichen planus or cicatricial pemphigoid. (wikipedia.org)
Eruptions1
  • A number of associated cutaneous findings have been reported in up to 15% of these patients including lichen planus-like eruptions (LP). (thedoctorsdoctor.com)
Eczema1
  • For the past decade, King has developed methods for using JAK inhibitors to treat a variety of skin diseases - including eczema, vitiligo, granuloma annulare, sarcoidosis, and erosive lichen planus. (sflorg.com)
Occur1
Patients3
  • [ 20 ] Additionally, microRNA 4484 (miR-4484) has been found to be significantly up-regulated in the salivary exosomes of patients with oral lichen planus. (medscape.com)
  • Forms of treatment therapy is intended for patients as a result of vaginal cancers. (dablab.ru)
  • For studying tissue specimens derived from patients with immunological disorders, the synthesised fluorescent antibody detects the human antibody forming an antibody complex ( Figure 1 ). (adejournal.com)
Symptoms1
Treatment1
  • As far as preventing cancer from forming there is no evidence that any treatment is more effective than placebo . (bauersmiles.com)
Reaction3
  • The expression or unmasking of the lichen planus antigen may be induced by drugs (lichenoid drug reaction), contact allergens in dental restorative materials or toothpastes (contact hypersensitivity reaction), mechanical trauma (Koebner phenomenon), viral infection, or other unidentified agents. (medscape.com)
  • Therefore, the present study aimed to investigate the frequency of human papillomavirus (HPV) DNA in oral lichen planus (OLP) tissue samples by the polymerase chain reaction (PCR) method. (magiran.com)
  • Lichen planus (LP) is thought to be caused by a T cell-mediated autoimmune reaction against basal epithelial keratinocytes in people with genetic predisposition. (msdmanuals.com)
Relatively common2
Diagnose2
  • A careful examination of the affected skin or mouth can help your doctor diagnose lichen planus. (natural-health-news.com)
  • I took the opportunity to study the case histories that I helped to maintain, which had a very positive result when, during my posting in Oral Medicine and Radiology, I was able to diagnose an erosive Lichen Planus in a patient, later confirmed histopathologically. (dentistrypersonalstatement.com)
Prevalence1
Occurs1
  • Generic DDAVP is a man-made form of a hormone that occurs naturally in the pituitary gland. (doctor777mg.com)
Malignant2
  • Recent data suggest that oral lichenoid reactions (OLR) present a greater percentage of malignant transformation than oral lichen planus (OLP). (ecancer.org)
  • The possibility of their degeneration into malignant forms of skin cancer determines the relevance of acquaintance with this disease. (medic-journal.com)
Markings1
  • Lichenification in the form of thickened skin, exaggerated skin markings and lichen type scale which is shiny rather than flaking. (vulvovaginaldisorders.org)
Rarely1