• This study sought to evaluate the costs and benefits of rinderpest eradication from Ethiopia and Kenya. (au-ibar.org)
  • Post-Eradication Programme (https://www.woah. (cdc.gov)
  • The concerted global effort to overcome rinderpest dates back many decades, and was brought to a successful conclusion by the Global Rinderpest Eradication Programme led by FAO in Africa, the Middle East and Asia. (thedairysite.com)
  • For more than four decades, AU-IBAR has coordinated major continent-wide efforts aimed at the eradication of rinderpest through several projects, notably the Joint Project Number 15 on Rinderpest (JP-15: 1962-1975), the Pan-African Rinderpest Campaign (PARC: 1986-1998), the African Wildlife Veterinary Project (AWVP: 1998-2000) and the Pan-African Programme for the Control of Epizootics (PACE: 1999-2007). (au-ibar.org)
  • Caused by a morbillivirus (same family as rinderpest), a global eradication programme is in hand and a DEVA test is being developed to distinguish between natural infection and vaccinate. (veterinary-practice.com)
  • The PPR-GCES is being implemented through the PPR Global Eradication Programme (PPR GEP) coordinated at the global level by the Joint FAO/OIE PPR Secretariat which was established in March 2016. (iga-goatworld.com)
  • Indeed, although excellent vaccines and disease diagnostic tests exist currently for immediate and effective implementation of PPR eradication programme (s), the need to encourage and support PPR research activities which results might help in refining PPR eradication programme (s) for better efficiency and for speeding up the course of the campaigns was foreseen in the PPR-GCES. (iga-goatworld.com)
  • In total, FAO estimates that eradication of rinderpest has meant some USD 920 million in annual economic benefits in Africa alone. (thedairysite.com)
  • For centuries, Rinderpest outbreaks caused the death of millions of cattle, buffalo, yak and wild animals across Africa, Asia and Europe. (woah.org)
  • Similarly, in Africa, the first veterinary school was founded in Egypt in 1827 to control Rinderpest. (woah.org)
  • In Asia, the Indian Veterinary Research Institute was established in 1913 to develop a Rinderpest vaccine, while in Africa, the Pan African Veterinary Vaccine Centre of the African Union (AU-PANVAC) began operating in 1986. (woah.org)
  • According to the UN's Food and Agriculture Organization (FAO), ovine rinderpest was first discovered in 1942 in West Africa. (acsh.org)
  • These developments were crucial in providing vaccine to eliminate rinderpest in its final strongholds in rural Africa.This was later improved further by using a weakened, or attenuated, virus. (animalresearch.info)
  • Founded in 1951 to study the epidemiological situation and fight rinderpest in Africa, AU-IBAR's mandate covers all aspects of animal resources, including livestock, fisheries and wildlife, across the entire African continent. (au-ibar.org)
  • Established as the Interafrican Bureau of Epizootic Diseases (IBED) in 1951 to study the epidemiological situation of and commence the fight against rinderpest in Africa, the organization today bears the name African Union - Interafrican Bureau for Animal Resources (AU-IBAR). (au-ibar.org)
  • Rinderpest has been a scourge throughout Asia, Africa and Europe, and has often been spread by trade and war. (srcf.net)
  • Rinderpest (RP) is highly infectious and fatal disease of Cattle that caused significant economic catastrophes in Africa. (com.et)
  • For the purpose of replenishing RP vaccine reserve for Africa that is required in case of possible resurgence of the disease, the World Organization for Animal Health (WOAH) selected NVI to produce the vaccine and the African Union PanAfrican Veterinary Vaccine Quality Control Center (AU-PANVAC) as Rinderpest Vaccine Holding Facility (RHF). (com.et)
  • Today, thanks to the efforts of FAO along with a host of other international organizations and national veterinary services, rinderpest has been wiped from the face of the earth. (thedairysite.com)
  • Far from seeing eradication as the end of the story, FAO views it as the beginning of an opportunity to conquer other devastating veterinary diseases, using the lessons learned from rinderpest. (thedairysite.com)
  • However, eradication campaign have the potential to continue making positive contributions to veterinary research and improved animal disease management. (thedairysite.com)
  • National and regional networks of veterinary laboratories that perform diagnostics and control the quality of vaccines followed suit to tackle Rinderpest. (woah.org)
  • Rinderpest has been a significant catalyst for the birth and development of modern veterinary science and its eradication is a monumental victory for the discipline. (srcf.net)
  • Now that the attempted eradication of Rinderpest was successful, veterinary experts are recommending that the next target be "goat plague. (furfarmandfork.com)
  • The National Veterinary Institute (NVI) significantly contributed for the eradication of the disease through production of quality vaccines for which it was recognized in March 2022 during the 10th anniversary marking its eradication. (com.et)
  • vaccine strains of rinderpest virus, the main findings of this review. (cdc.gov)
  • citation needed] During the twentieth century, there were a series of campaigns to eradicate rinderpest, a viral disease that infected cattle and other ruminants and belonged to the same family as measles, primarily through the use of a live attenuated vaccine. (wikipedia.org)
  • It is possible because a vaccine exists , and we know that the cattle version of rinderpest has already been eradicated. (acsh.org)
  • A team of experts designated by WOAH made site inspection of NVI's Rinderpest vaccine production facility from Oct 18-21, 2022 to ensure its compliance with the set standards as regards to GMP, Biosafety and Biosecurity. (com.et)
  • In 1988, the World Health Organization (WHO), Rotary International, the United Nations Children's Fund (UNICEF), and the United States Centers for Disease Control and Prevention (CDC) passed the Global Polio Eradication Initiative. (wikipedia.org)
  • With so much progress already made, the announcement of a global polio eradication program was made in 1988 by the WHO and other international organizations. (everything-everywhere.com)
  • The first such disease and perhaps the most famous example of complete eradication is smallpox. (everything-everywhere.com)
  • So far, these are the only two diseases for which there has been a declaration of complete eradication. (everything-everywhere.com)
  • The far-reaching consequences of the "cattle plague" at social and economic levels led to the creation of the World Organisation for Animal Health, whose efforts and collaboration with international partners paved the way for the complete eradication of the disease, with the last case reported in 2001. (woah.org)
  • This method was also independently developed and used to eradicate rinderpest in Western Russia by 1928. (srcf.net)
  • Ovine Rinderpest Outbreak in Europe: Wait, Wasn't That Eradicated? (acsh.org)
  • However, today, Bulgaria has announced an outbreak of ovine rinderpest . (acsh.org)
  • However, it was after the 1920 outbreak of Rinderpest in Belgium that joint action to address the global concern received new impetus. (woah.org)
  • Due to the high mortality rate, famine often followed a rinderpest outbreak as people were dependent on their cattle for food, transport and skins. (srcf.net)
  • In the 18th century Giovanni Maria Lancisi, the physician of Pope Clement XI, was instructed to deal with a rinderpest outbreak that had killed over 26,000 papal cattle. (srcf.net)
  • At the time, the wildebeest population was increasing, benefiting from the recent eradication of rinderpest following an outbreak in the crater in 1958. (blogspot.com)
  • This underlines the importance of supporting programmes that aim to avert the return of the rinderpest pathogen, as well as those focusing on improved disease management and prevention of other diseases affecting the world's livestock, biodiversity and food and nutritional security. (thedairysite.com)
  • The eradication of infectious diseases is the reduction of an infectious disease's prevalence in the global host population to zero. (wikipedia.org)
  • Five more infectious diseases have been identified as of April 2008[update] as potentially eradicable with current technology by the Carter Center International Task Force for Disease Eradication-measles, mumps, rubella, lymphatic filariasis (elephantiasis) and cysticercosis (pork tapeworm). (wikipedia.org)
  • The targeting of infectious diseases for eradication is based on narrow criteria, as both biological and technical features determine whether a pathogenic organism is (at least potentially) eradicable. (wikipedia.org)
  • The targeted pathogen must not have a significant non-human (or non-human-dependent) reservoir (or, in the case of animal diseases, the infection reservoir must be an easily identifiable species, as in the case of rinderpest). (wikipedia.org)
  • So far, only two diseases have been successfully eradicated-one specifically affecting humans (smallpox) and one affecting cattle (rinderpest). (wikipedia.org)
  • The global eradication of Rinderpest gives reason to be optimistic when it comes to fighting infectious animal diseases. (woah.org)
  • Both diseases have viral origin and share features that made them targets for eradication since reliable diagnostic tools and safe and efficacious vaccines were made available, along with political and financial support. (woah.org)
  • However, they are not the only diseases where eradication efforts are underway. (everything-everywhere.com)
  • Peste des petits ruminants (PPR) and Rinderpest (RP) are highly contagious viral diseases of domestic and wild ruminants inducing high morbidity and mortality. (europa.eu)
  • In the world, only a few diseases are recognized as eradicated, such as smallpox (1980) in humans or rinderpest (2011) in animals. (iswavld2023.org)
  • In the 'all other' category, three items refer to disease eradication, three to to new vaccines, and two each to the Millennium Development Goals and HIV/AIDS prevention. (childsurvival.net)
  • Some vaccines have been so effective they have resulted in eradication of disease. (bio-rad-antibodies.com)
  • Strict control of animal movement during outbreaks was important for reducing the threat of rinderpest across Europe, but it was the development of vaccines that set the wheels in motion for removing the virus globally. (srcf.net)
  • Although early vaccines could be used to provide long-term immunity against rinderpest, there were drawbacks. (srcf.net)
  • In 2011, the global public health community declared the eradication of rinderpest, a severe viral disease of cattle. (acsh.org)
  • Peste des petits ruminants (PPR) is a burdensome viral disease primarily affecting small ruminants, which is currently targeted for eradication by 2030 through the implementation of a Global Control and Eradication Strategy (PPR GCES). (bvsalud.org)
  • The last confirmed case of Rinderpest occurred in Kenya in 2001, and it was declared eradicated by the World Health Organization in 2011. (everything-everywhere.com)
  • Speakers include Prof Peter Roeder (rinderpest eradication), Dr Bernadette Abela-Ridder (WHO), Dr Thumbi Mwangi (Kenya), Dr Ryan Wallace (CDC), Terence Scott (GARC), Sean Shadomy (FAO). (unitedagainstrabies.org)
  • Rinderpest, also known as cattle plague, is only tion. (cdc.gov)
  • Rinderpest (from the German for cattle plague) is an infectious disease that has killed hundreds of millions of cattle over hundreds of years, often causing famine. (animalresearch.info)
  • This year the eradication of rinderpest, or cattle plague as it is also known, will be officially declared making it only the second disease in history to be systematically eliminated by human intervention. (srcf.net)
  • In support of this effort, in 2015, FAO and the United Nations (FAO) and the World Organ- WOAH started the Sequence and Destroy project, isation for Animal Health (WOAH, formerly OIE) which enabled whole-genome sequencing of rin- jointly declared global freedom from rinderpest. (cdc.gov)
  • Speakers include Dr Reildrin Morales (The Philippines), Katinka de Balogh (FAO), Vivian Iwar (ECOWAS), Marija Popovic (WOAH), Andre Coetzer (GARC), Thomas Mueller (FLI), Anna Fahrion (FLI), Madi Savadogo (Institut de Recherche en Sciences de la Sante). (unitedagainstrabies.org)
  • When large smallpox outbreaks diminished as part of the smallpox eradication campaign, the World Health Organization turned to field workers armed with pictures of smallpox victims to survey villagers and find cases of the disease [ 2 ]. (biomedcentral.com)
  • Unlike many of our pathogenic foes, such as AIDS, tuberculosis and cholera, rinderpest does not often hit the headlines, but this pathogen has had an astonishing influence on humankind, and a huge effort has been spent combating it. (srcf.net)
  • Dur- reduce global stocks of rinderpest virus-containing ing June-October 2021, a review was conducted to material (RVCM). (cdc.gov)
  • The concept of disease eradication is sometimes confused with disease elimination, which is the reduction of an infectious disease's prevalence in a regional population to zero, or the reduction of the global prevalence to a negligible amount. (wikipedia.org)
  • After two years' detailed analysis of national records, the global eradication of smallpox was certified by an international commission of smallpox clinicians and medical scientists on 9 December 1979, and endorsed by the General Assembly of the World Health Organization on 8 May 1980. (wikipedia.org)
  • Beyond the remarkable achievement of global Rinderpest eradication itself, what was learnt will benefit generations to come. (woah.org)
  • The authors of the article go on to call for a global program for the eradication of ovine rinderpest. (acsh.org)
  • UK-funded research and innovation has contributed to significant global advances, including a dramatic reduction of child deaths from malaria, eradication of the devastating livestock disease rinderpest, reduction of gender-based violence and building the case for climate action. (royalsociety.org)
  • Following the conclusion of the first phase of the PPR Global Eradication Program (PPR GEP) (2017-2021), the present work focuses on the disease situation and status of the eradication campaign in the fourteen countries of the PPR GCES Middle Eastern Roadmap as well as Egypt. (bvsalud.org)
  • Further confusion arises from the use of the term 'eradication' to refer to the total removal of a given pathogen from an individual (also known as clearance of an infection), particularly in the context of HIV and certain other viruses where such cures are sought. (wikipedia.org)
  • Household income across Ethiopia rose by €38.1 million as a result of rinderpest control and eradication. (thedairysite.com)
  • Folklore maintains that Genghis Khan sent rinderpest-infected cattle into the herds of his enemies to wipe out their food supply, making them easier to conquer, write the media team at the World Food and Agriculture Organisation (FAO). (thedairysite.com)
  • With a 100% death rate in some herds, the Rinderpest virus can be rapidly transmitted among cloven-hoofed animals (mainly cattle and buffalo). (woah.org)
  • Although rinderpest has been eradicated from fields and pastures, virus samples remain quite alive in the dozens of laboratories that participated in the control campaign. (thedairysite.com)
  • The use of vaccination programs before the introduction of an eradication campaign can reduce the susceptible population. (wikipedia.org)
  • Much of the success of the vaccination campaign was due to technologies developed to detect the presence of the rinderpest virus in populations and to differentiate between strains. (animalresearch.info)
  • DISPATCHES category A or B or dual-category rinderpest-hold- vaccination of cattle with peste des petits rumi- ing facilities (RHFs) (https://www.oie.int/en/ nants virus (PPRV) does not provide protective disease/rinderpest/#ui-id-3). (cdc.gov)
  • mark progress towards RVCM sequestration and RVCM comprises field and laboratory strains of destruction 10 years after eradication. (cdc.gov)
  • In 1893 the explorer Fredrick Lugard observed the scale of the rinderpest pandemic in Maasailand. (srcf.net)
  • Rinderpest isn't as well known as smallpox, mainly because it doesn't infect humans. (everything-everywhere.com)
  • Rinderpest is a highly contagious disease that had been known since humans initiated the domestication of livestock. (woah.org)
  • Although Rinderpest has been officially eradicated since 2011, the box is not closed yet as laboratories continue harbouring the costly virus and researchers hope to learn more about the disease. (thedairysite.com)
  • A combination of smallpox and famine due to rinderpest brought about a huge reduction in the population of native Africans. (srcf.net)
  • Since many of these limitations are shared by many of the investigated countries, the international cooperation and harmonization of control efforts appears crucial to making PPR eradication attainable in the Middle East. (bvsalud.org)
  • This project supported community-based animal health worker (CAHW) systems in pastoralist areas, and contributed to the final eradication of rinderpest under the Pan African Program for the Control of Epizootics. (tufts.edu)
  • In disease control, eradication, and surveillance must be distinguished. (iswavld2023.org)
  • Such an approach was used successfully in the eradication of rinderpest, and in the control of foot and mouth disease as well as malaria. (actionforanimalhealth.org)
  • Rinderpest virus infects cattle with an 80-90% mortality rate ANCHOR and symptoms include fever, discharge from nose and eyes, ulceration, diarrhoea and dehydration. (animalresearch.info)
  • But there is another type of rinderpest virus that causes disease in sheep and goats. (acsh.org)
  • These were developed by serially growing the rinderpest virus in live animals such as goats, rabbits or pigs that could propagate the virus but did not develop the disease. (srcf.net)
  • Pest de Petits Ruminants or "goat plague" is a viral infection related to rinderpest that affects sheep, goats, and deer (important as vectors for the virus). (furfarmandfork.com)
  • Subge- and World Organisation for Animal Health have since nomic fragments of morbillivirus nucleic acid not made great strides in consolidating, sequencing, and de- capable of incorporation into a replicating morbil- stroying stocks of rinderpest virus-containing material, livirus or morbillivirus-like viruses are not consid- currently kept by only 14 known institutions. (cdc.gov)
  • Rinderpest virus was arguably the first weapon used in what is now called "bioterrorism. (thedairysite.com)
  • Thankfully, the type of virus that causes rinderpest in cattle is still gone. (acsh.org)
  • Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit On episode #105 of the podcast This Week in Virology, Vincent, Dickson, Alan, and Rich review eradication of rinderpest, endogenous hepatitis B virus in the zebra finch genome, and identification of the cell receptor for an extinct retrovirus. (virology.ws)
  • ANCHOR In addition, genetic sequencing of virus samples allowed researchers to identify routes of transmission of rinderpest between regions and discover new sources of the disease. (animalresearch.info)
  • Eradication of a killer virus sounds like a noble goal. (juliusruechel.com)
  • Decades of concerted efforts from governments and local organizations supported by the World Organisation for Animal Health (OIE) and the Food and Agriculture Organization of the United Nations (FAO), along with other partners, resulted in the eradication of Rinderpest through mass vaccination campaigns of cattle. (woah.org)
  • Vaccination is far more likely than culling to contribute to TB eradication, because vaccination reduces infection rates in badgers14,15, while culling increases them10. (brianmay.com)
  • In the latter case, coordinated vaccination programs across multiple countries led to the eradication of this disease in 2011 (OIE) . (fve.org)
  • Economic considerations, as well as societal and political support and commitment, are other crucial factors that determine eradication feasibility. (wikipedia.org)
  • For VSF G he managed the rinderpest eradication program in parts of Southern Sudan and initiated the training of more than 1300 Community Based Animal Health Workers. (invelco.org)
  • The school was established in 1762 and specialists were trained to combat threats such as rinderpest. (srcf.net)
  • Christine M. Budke, Dirk U. Pfeiffer, Bryony A. Jones, Guillaume Fournié, Younjung Kim, Mariana Marrana, Heather L. Simmons and full-length genomic material, including from In 2021, the world marked 10 years free from rinderpest. (cdc.gov)
  • I've done an entire episode on smallpox so I won't belabor the point here, but smallpox probably killed more people than anything else in the 100 years prior to its eradication. (everything-everywhere.com)
  • Reports point to the origins of Rinderpest in Central Asia and its rapid spread to the rest of the continent and across Europe, following trade and migration routes. (woah.org)
  • The first animal disease to have been eradicated, Rinderpest is highly contagious and has a long history of loss in animal populations and economic disruption. (woah.org)
  • To this date, Rinderpest eradication remains an unprecedented milestone in the history of animal health. (woah.org)
  • Disease eradication and surveillance: which method for which goal? (iswavld2023.org)
  • Some of the economic returns associated with the eradication of Rinderpest are pretty amazing, so it seems like PPR would be a reasonable next step. (furfarmandfork.com)
  • The only comparable feat in the domain of public health is the eradication of Smallpox, a human disease, which was achieved in the 1980s. (woah.org)