EpitheliumApoptosisApoptosis Regulatory ProteinsCaspasesCaspase 3Proto-Oncogene Proteins c-bcl-2Inhibitor of Apoptosis ProteinsEpithelium, CornealDNA FragmentationIn Situ Nick-End LabelingEpithelial Cellsbcl-2-Associated X ProteinCell Line, TumorX-Linked Inhibitor of Apoptosis ProteinSignal TransductionCell SurvivalCells, CulturedApoptosis Inducing FactorCASP8 and FADD-Like Apoptosis Regulating ProteinCaspase 9Caspase InhibitorsSeminiferous EpitheliumTumor Suppressor Protein p53MitochondriaCaspase 8Fas Ligand ProteinCell ProliferationEnzyme ActivationTumor Cells, CulturedBlotting, WesternImmunohistochemistryRetinal Pigment EpitheliumCell LineCytochromes cbcl-X ProteinRNA, MessengerAnnexin A5Cell DivisionFlow CytometryProto-Oncogene ProteinsCell CycleCysteine Proteinase InhibitorsAmino Acid Chloromethyl KetonesReverse Transcriptase Polymerase Chain ReactionMice, Inbred C57BLAntineoplastic AgentsIntestinal MucosaOlfactory MucosaPoly(ADP-ribose) PolymerasesEnzyme InhibitorsTransfectionTime FactorsDown-RegulationDose-Response Relationship, DrugReactive Oxygen SpeciesRNA, Small InterferingUp-RegulationTNF-Related Apoptosis-Inducing LigandCell DifferentiationRespiratory MucosaJurkat CellsMice, KnockoutMembrane GlycoproteinsCell DeathTumor Necrosis Factor-alphaGene ExpressionPhosphorylationGene Expression RegulationHL-60 CellsCaspase 7Membrane Potential, MitochondrialMice, TransgenicNecrosisMembrane ProteinsGenes, bcl-2NF-kappa BCarrier ProteinsGene Expression Regulation, Neoplasticbcl-2 Homologous Antagonist-Killer ProteinProto-Oncogene Proteins c-aktDNA DamageMicroscopy, ElectronCytochrome c GroupMyeloid Cell Leukemia Sequence 1 ProteinNeoplasm ProteinsModels, BiologicalBH3 Interacting Domain Death Agonist ProteinRats, Sprague-DawleyCorneaStaurosporineProtein-Serine-Threonine KinasesMolecular Sequence DataDNA-Binding ProteinsIn Situ HybridizationTracheaOxidative StressTranscription FactorsDisease Models, Animalbcl-Associated Death ProteinMutation