Epithelium tissues. Medical search. Frequent questions

Olfaction requires orthonasal or retronasal airflow to transport odor-bearing particles up to the olfactory epithelium located at the apex of the nasal cavity. (nih.gov)
Nasal respiratory and olfactory epithelium were found to be early pollutant targets. (rti.org)

The epigenetic plasticity of amphibian retinal pigment epithelium (RPE) allows them to regenerate the entire retina, a trait known to be absent in mammals. (nih.gov)
In the retina, myosin VIIA is found primarily in a thin layer of cells called the retinal pigment epithelium (RPE). (medlineplus.gov)

[1] It is composed of non-keratinized, stratified squamous epithelium with goblet cells , stratified columnar epithelium and stratified cuboidal epithelium (depending on the zone). (wikipedia.org)
The conjunctiva consists of unkeratinized, both stratified squamous and stratified columnar epithelium, with interspersed goblet cells . (wikipedia.org)
The epithelium was hyperplastic stratified squamous type which was parakeratinised in nature (figure 1). (ispub.com)

In previous work, human fetal intestinal cells developed epithelium without mesenchyme following implantation in mice. (ca.gov)

ASL glucose concentrations are the net result of diffusion of glucose from blood and interstitial fluid across the respiratory epithelium into the ASL, and removal of glucose from ASL by epithelial glucose transport processes. (ersjournals.com)
Respiratory secretions, bronchoalveolar lavage samples, and tissue specimens can be examined using cytologic and histologic techniques. (medscape.com)
Tissue from the upper or lower respiratory tract, sputum samples, and samples obtained by nasopharyngeal washing, bronchoalveolar lavage, and biopsy may be submitted for viral culture. (medscape.com)
Covered in respiratory epithelium and mucous cells, this is the most substantial part of the nasal cavity. (nih.gov)

The ERK pathway plays a critical role in embryonic development and tissue repair because it instructs cells to multiply and start dividing, but when overactivated cancer growth often occurs. (genengnews.com)
Placentas have been classified on the basis of the relationship between maternal and embryonic tissues. (britannica.com)

During the inflammatory response, immune cells egress from the circulation and follow a chemotactic and haptotactic gradient within the tissue, interacting with matrix components in the stroma and with parenchymal cells, which guide them towards the sites of inflammation. (hindawi.com)
Polarized epithelial cells compartmentalize tissue cavities and are often exposed to inflammatory challenges such as toxics or infections in non-lymphoid tissues. (hindawi.com)
Particular attention has been paid to elucidating how leukocytes can migrate through the stroma, the way these cells remodel their morphology and sense cues that guide them towards dysfunctional tissue areas. (hindawi.com)
Compared to the endothelium, the molecular mechanisms involved in the interaction of infiltrated or tissue-resident immune cells with parenchymal barriers have not been so extensively studied. (hindawi.com)
On the one hand, similar to endothelial cells, parenchymal epithelia must guide leukocytes to traverse them in order to reach a localized inflammatory focus, for example, in the lung or intestinal mucosa. (hindawi.com)
So far, most of the in vivo and in vitro approaches to study leukocyte migration across the tissue parenchyma have addressed the role of each single tissue barrier that immune cells encounter in their journey to the inflammatory focus. (hindawi.com)
Tissues are groups of cells with a common structure (form) and function (job). (exploringnature.org)
Previous molecular characterizations of mammary stem cells (MaSC) have utilized fluorescence-activated cell sorting or in vitro cultivation of cells from enzymatically dissociated tissue to enrich for MaSC. (frontiersin.org)
We isolated four categories of cells from mammary epithelium of female calves: bromodeoxyuridine label retaining epithelial cells (LREC) from basal (LRECb) and embedded layers (LRECe), and epithelial control cells from basal and embedded layers. (frontiersin.org)
Tissues with rapidly dividing cells may be especially vulnerable to carcinogens. (cdc.gov)
Simple cuboidal epithelium is a type of epithelium that consists of a single layer of cuboidal (cube-like) cells which have large, spherical and central nuclei. (wikipedia.org)
Human gamma delta T-cells in the epithelium of the gut and in the inflamed synovial tissue preferentially express the V gamma 8 T-cell receptor chain. (ox.ac.uk)
Melanomacrophage centers (MMCs) consist of macrophages, such as phagocytic cells and fragments, mainly erythrocytes and pigments, such as melanin, hemosiderin and lipofuscin, located in the reticuloendothelial liver tissue, kidney and pancreas ( Agius and Roberts, 2003 AGIUS, C. (scielo.br)
To enable tissue renewal, human tissues constantly eliminate millions of cells, without jeopardizing tissue integrity, form and connectivity. (pasteur.fr)
Scientists from the Institut Pasteur and the CNRS today revealed a new process which allows eliminated cells to temporarily protect their neighbors from cell death, thereby maintaining tissue integrity. (pasteur.fr)
The scientists observed that when the mechanism is deactivated, the simultaneous elimination of several neighboring cells compromises tissue integrity. (pasteur.fr)
Tissue renewal involves the formation of new cells by cell division and the elimination of dead cells. (pasteur.fr)
The mechanisms that regulate the ability of epithelia to maintain their integrity in contexts involving large numbers of eliminated cells remain poorly understood, despite the fact that this situation occurs regularly during embryogenesis or the maintenance of adult tissues. (pasteur.fr)
We already knew that this pathway plays a key role in regulating cell survival in epithelial tissue, but we were surprised to observe such protective dynamics between cells, " comments Romain Levayer, Head of the Cell Death and Epithelial Homeostasis Unit at the Institut Pasteur and last author of the study. (pasteur.fr)
The scientists' research also shows that inhibiting this protective mechanism has a drastic effect on epithelial tissue: cell elimination becomes random and neighboring cells can be eliminated simultaneously, leading to repeated losses of connectivity. (pasteur.fr)
The elimination of groups of neighboring cells is never observed in epithelial tissue in normal conditions, when the EGFR-ERK pathway is not deliberately inhibited, even if a large number of cells are eliminated. (pasteur.fr)
Surprisingly, epithelial tissue is highly sensitive to the spatial distribution of eliminated cells. (pasteur.fr)
The scientists' observations confirm that tissues need to develop mechanisms preventing the elimination of neighboring groups of cells. (pasteur.fr)
[6] Additional cells present in the conjunctival epithelium include melanocytes , T and B cell lymphocytes . (wikipedia.org)
Human tissue-engineered colon forms from postnatal progenitor cells: an in vivo murine model. (ca.gov)
Resident memory (T RM ) cells are a distinct tissue-localized T cell lineage that is crucial for protective immunity in peripheral tissues. (frontiersin.org)
Recent studies in mouse tumor models have shown that T RM cells are induced by cancer vaccines delivered in peripheral tissue sites, or by the depletion of regulatory T cells. (frontiersin.org)
Such tumor-specific T RM cells are recognized as both necessary and sufficient for long-lived protection against tumors in peripheral tissue locations. (frontiersin.org)
Following effective priming in lymph nodes, T cells traffic to tumors and other peripheral tissues. (frontiersin.org)
whereas T EM cells were shown to recirculate predominantly through blood, and peripheral tissues ( 10 ). (frontiersin.org)
In the early 2000's, large and persistent populations of antigen (Ag)-specific CD8 T cells in peripheral tissues were initially classified as T EM cells in recirculation from the blood ( 8 , 11 ). (frontiersin.org)
We develop new technologies to map and perturb the main physical properties that determine how cells and tissues grow, move, invade and remodel. (ibecbarcelona.eu)
Surprisingly, some cells in the tissue barely stretch, while others become 'superstretched', increasing their area more than ten times. (ibecbarcelona.eu)
The theory that metaplasia causes endometriosis is supported by the fact that endometrial cells and peritoneal cells derive from the same celomic wall epithelium. (medscape.com)

3) Always had one fixed (basal) section attached to underlying connective tissue. (exploringnature.org)
4) Has no blood vessels but can soak up nutrients from blood vessels in connective tissue underneath. (exploringnature.org)
The hematoxylin and eosin stained section showed epithelium and connective tissue. (ispub.com)

Pneumothorax and pneumomediastinum occur in 1 to 2% of normal neonates, probably because large negative intrathoracic forces created when the neonate starts breathing occasionally disrupt alveolar epithelium, which allows air to move from the alveoli into extra-alveolar soft tissues or spaces. (msdmanuals.com)

In humans, angiotensin-converting enzyme inhibitors, a potent class of antihypertensive agents, lower blood pressure at least partially by favoring enhanced kinin accumulation in plasma and target tissues. (nature.com)

Current model of the mechanisms controlling glucose concentrations in the surface liquid lining the airway and distal lung epithelium. (ersjournals.com)
TGF-β1 is a major mediator of airway tissue remodelling during atopic asthma and affects tight junctions (TJs) of airway epithelia. (springer.com)
In summary, we demonstrate a role of motile cilia in TGF-β1 sensing and showed that TGF-β1 disturbs TJ permeability of conductive airway epithelia by redistributing CLDN3 from TJs into cell nuclei. (springer.com)
The authors conclude that the effects of epithelium removal on the responsiveness of airway smooth muscle reflect differential influences on epithelium derived modulating factors, rather than just the loss of a diffusion barrier. (cdc.gov)

Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. (lu.se)

CIL:26586, Homo sapiens, cervical epithelium. (cellimagelibrary.org)
Under normal conditions, this tissue is continuously stimulated by sympathetic signals via the superior cervical ganglia to keep the nasal cavity uncongested. (nih.gov)

Our understanding of the role of glucose transport in the lung and the mechanisms that regulate glucose movement across the human lung epithelium lags far behind that of the gut and kidney. (ersjournals.com)
We use intestinal and kidney organoids to study how epithelia adopt three-dimensional shapes that closely resemble their structure in vivo. (ibecbarcelona.eu)

Myosin VIIA is made in the inner ear and in the retina, which is the light-sensitive tissue at the back of the eye. (medlineplus.gov)
Myosin VIIA probably plays a role in the development and maintenance of this tissue, which supports and nourishes the retina. (medlineplus.gov)

Endometriosis is defined as the presence of endometrial glandular tissue outside of the uterus. (medscape.com)

Here we review evidence showing that apicobasal polarity regulates the inflammatory response: various polarized epithelia asymmetrically secrete chemotactic mediators and polarize adhesion receptors that dictate the route of leukocyte migration within the parenchyma. (hindawi.com)
Histopathologic findings exhibited here, included an intact mucosal epithelium, and an acute inflammatory response, as well as findings indicative of this patient's malabsorption symptoms. (cdc.gov)

Histological examination of tissues starts with surgery , biopsy or autopsy . (fact-archive.com)
The specimens for histological examination were dissected from the experimental sites and the oral soft tissues surrounding the exposed mandibular first molar were excised. (who.int)

Fatty acid binding proteins are small cytoplasmic lipid binding proteins that are expressed in a tissue specific manner. (rndsystems.com)
Proteins secreted by the epididymal epithelium. (bvsalud.org)
These proteins are both tissue- and species-specific. (bvsalud.org)

The epithelium was removed mechanically from alternate strips. (cdc.gov)

We believe that successfully combining our current knowledge about leukocyte extravasation, three-dimensional migration through the stroma and the sequential interactions with parenchymal cell barriers, which include adopting unified experimental models, will help shed light on the entire migratory route of each immune cell type and on the specificity of the innate inflammatory responses in each type of tissue. (hindawi.com)
Overall, these findings emphasize the linkage between breast specific epigenetic regulation and tissue specificity of cancer. (johnshopkins.edu)

Estrone is an estrogenic hormone secreted by the ovaries and adipose tissues. (hmdb.ca)

[ 7 ] This theory also is supported by development of endometriosis in women who lack normal endometrial tissue, such as those with Turner syndrome or uterine agenesis . (medscape.com)

Simple cuboidal epithelium is found on the surface of ovaries, the lining of nephrons, the walls of the renal tubules, parts of the eye and thyroid, and in salivary glands. (wikipedia.org)
Simple cuboidal epithelium commonly differentiates to form the secretory and duct portions of glands. (wikipedia.org)

and skeletal muscle tissue. (nih.gov)
Differential effects of epithelium removal on the responsiveness of guinea-pig tracheal smooth muscle to bronchoconstrictors. (cdc.gov)
The leukotrienes LTC4, LTD4 and LTE4, the potent bronchoconstrictor 5-hydroxytryptamine (5HT), and the thromboxane mimetic U-44069 were added to the bathing solution and the effects on contractile reactivity of the muscle tissues were investigated. (cdc.gov)

In this study, we investigated the epigenetic plasticity of adult murine RPE to identify possible mechanisms that prevent mammalian RPE from regenerating retinal tissue. (nih.gov)
It is suggested that tissue differentiation, mediated mostly by epigenetic modifications, could guide tissue-specific susceptibility and protective mechanisms against cancer. (johnshopkins.edu)
This will inform in-depth mechanistic assays at the cell, tissue and organ scales to identify the key mechanisms underpinning regulation of lung function in health and disease. (nottingham.ac.uk)

The test substance (R)-(-)-butane-1,3-diol was assessed by OECD 492 (in vitro reconstructed human cornea-like epithelium (RhCE) test method for chemicals not requiring classification and labelling for eye irritation or serious eye damage) to provide classification of chemicals concerning their eye irritation potential under GLP conditions. (europa.eu)

1993) A kallikrein-like enzyme in human vascular tissue. (nature.com)
1999) Identification of immunoreactive tissue prokallikrein on the surface membrane of human neutrophils. (nature.com)
Human epithelia are tissues found in several parts of the body (such as the epidermis and internal mucosa). (pasteur.fr)
We generated tissue-engineered colon (TEC) from postnatal human organoid units. (ca.gov)
Results: Human TEC demonstrated a simple columnar epithelium. (ca.gov)
Immunofluorescence staining demonstrated human origin and the three differentiated cell types of mature colon epithelium. (ca.gov)

To prioritise pathways we will undertake high-throughput functional genomic screens using CRISPR, perform lung digital spatial transcriptomic profiling and utilise informative cell and tissue models. (nottingham.ac.uk)

Following treatment and subsequent incubation time, the viability of the tissues was determined using methyl thiazole tetrazolium (MTT) uptake and reduction. (europa.eu)
The viability of tissues was then expressed as a percent of negative control values. (europa.eu)
It is known that the maintenance of oral health in these situations depends not only on the viability of dental tissues, but also on the periodontal damage occurred and the emergency therapeutic procedures performed. (bvsalud.org)

Columnar epithelium lines the nasal cavity. (nih.gov)
It regulates the nasal airflow by controlling the blood volume in the erectile tissue on the inferior turbinate and anterior septum. (nih.gov)

By combining this physical information with systematic molecular perturbations and computational models we explore the principles that govern the interplay between chemical and physical cues in living tissues. (ibecbarcelona.eu)

The second theory holds that the serosal epithelium of the peritoneum undergoes metaplastic differentiation into endometrium-like tissue. (medscape.com)

[6] The epithelial layer contains blood vessels, fibrous tissue, and lymphatic channels. (wikipedia.org)
One theory is that endometrial tissue is spread by retrograde menstruation or by vascular and/or lymphatic spread. (medscape.com)

However if the tissue type is the main point and the organ is merely the source, the tissue type is indexed IM. (nih.gov)
A structured approach is essential, as the most common error in wound care management is rushing in to select the latest and greatest new wound dressings without actually giving thought to wound aetiology, tissue type and immediate aim. (ausmed.com.au)
A total of 295 traumatized teeth were assessed about history, type of dental trauma, and periodontal tissue damage detected during clinical and radiographic examination. (bvsalud.org)
Its severity may be classified according to the level of damage to the supporting tissues as well as to the type of fracture 3 . (bvsalud.org)

They also may be produced through manipulation of lesions or processing of tissue or secretions in the hospital or laboratory. (cdc.gov)

The histopathological examination of the tissue biopsied revealed it to be case of verrucous carcinoma with numerous dysplastic features. (ispub.com)

Histology is the study of tissue sectioned as a thin slice, using a microscope . (fact-archive.com)

To study cell and tissue dynamics we develop new technologies to measure physical forces at the cell-cell and cell-matrix interface. (ibecbarcelona.eu)

We develop new approaches to engineer epithelia in 3D. (ibecbarcelona.eu)
Using these approaches, we study the principles that govern the emergence of tissue shape from the bottom up. (ibecbarcelona.eu)

Soft, wet tissues are turned into a hard block. (fact-archive.com)
This soft, gelatinous, highly exuding tissue requires specific treatment. (ausmed.com.au)
Bacteria an d bacterial products cause inflamm ation of soft tissue. (researchgate.net)
However, the current use of blue light is not without its disadvantages since the oral soft tissues surrounding the tooth cannot be completely excluded from the area of light application. (who.int)

Inflammatory bowel disease (IBD) is a chronic condition driven by loss of homeostasis between the mucosal immune system , the commensal gut microbiota , and the intestinal epithelium . (bvsalud.org)

Translocation of NWs across the intestinal epithelium was investigated using confocal fluorescence microscopy directly after 24 h of exposure and was observed in 89% of Daphnia exposed to 40 nm NWs and in 11% of Daphnia exposed to 80 nm NWs. (lu.se)
Temperature used during treatment / exposure: The dosed tissues were placed in an incubator at 37 °C ± 1 °C, 5 ± 1% CO2 for 35 ± 1 minutes, and then returned to the sterile hood for the remainder of the 60-minute exposure period. (europa.eu)

How are these eliminations orchestrated to maintain tissue integrity and connectivity? (pasteur.fr)

By combining these technologies with computational analysis of cell shape and velocity we obtain a full experimental characterization of epithelial dynamics during tissue growth, wound healing and cancer cell invasion. (ibecbarcelona.eu)

Tissue types are usually indexed NIM with a specific organ IM. (nih.gov)

Other compound used to color tissue sections include saffron , silver salts and numerous artificial dyes originally developed to stain cloth fibers. (fact-archive.com)

Here we studied breast specific methylation in purified normal epithelium and its reflection in breast cancers. (johnshopkins.edu)
We established genome wide methylation profiles of various normal epithelial tissues and identified 110 genes that were differentially methylated in normal breast epithelium. (johnshopkins.edu)
We elaborated on one of them, TRIM29 (ATDC), and showed that its promoter was hypo-methylated in normal breast epithelium and heavily methylated in other normal epithelial tissues. (johnshopkins.edu)

Anatomy105

Organisms19

Diseases17

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment30

Phenomena and Processes39

Disciplines and Occupations2

Information Science3

Olfactory epithelium2

Retinal pigment ep2

Stratified squamous3

Mesenchyme1

Respiratory4

Embryonic2

Cells34

Connective3

Alveolar1

Target tissues1

Airway4

Mucous1

Cervical2

Kidney2

Retina2

Glandular1

Inflammatory response2

Histological2

Proteins3

Alternate1

Specificity2

Adipose1

Uterine1

Glands2

Muscle3

Mechanisms3

Vitro1

Human6

Lung1

Viability3

Nasal2

Cues1

Differentiation1

Lymphatic2

Type4

Secretions1

Examination1

Histology1

Cell and tissue1

Approaches2

Soft4

Immune1

Exposure2

Integrity1

Shape1

Types1

Include1

Normal3