miR-455-3p Is Negatively Regulated by Myostatin in Skeletal Muscle and Promotes Myoblast Differentiation. (bioss.com.cn)
Migration5
LPA acts as an autocrine/paracrine messenger through at least six G protein-coupled receptors (GPCRs), known as LPA 1-6 , to induce various cellular processes including wound healing, differentiation, proliferation, migration, and survival. (hindawi.com)
To identify novel molecular targets within the ubiquitination pathway that positively regulate migration we conducted a loss-of-function genetic screen using an epithelial cell line derived from human triple-negative breast cancer (MDAMB231) infected with a pooled shRNA interference library. (nature.com)
To date, RUNX2 has been involved in diverse physiological processes, including osteogenic differentiation of mesenchymal stem/stromal cells, chondrocyte hypertrophy, immunomodulation, vascular invasion and endothelial cell migration via modulating a variety of signaling cascades (e.g. (spandidos-publications.com)
LncRNA NEAT1 promotes proliferation, migration, invasion and epithelial-mesenchymal transition process in TGF-β2-stimulated lens epithelial cells through regulating the miR-486-5p/SMAD4 axis. (bioss.com.cn)
Discoidin domain receptor (DDR) is a collagen-activated receptor tyrosine kinase that plays critical roles in regulating essential cellular processes such as morphogenesis, differentiation, proliferation, adhesion, migration, invasion, and matrix remodeling. (encyclopedia.pub)
Tubule1
The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. (peprotech.com)
Cells18
Rhabdomyoblasts are early stage mesenchymal cells, having the potential to differentiate into a wide range of skeletal cells. (wikipedia.org)
irregular growth in the primitive form of these skeletal muscle cells, rhabdomyoblasts, are commonly associated with Rhabdomyosarcoma. (wikipedia.org)
Several unexpected findings in genetically altered mice have prompted research into the direction of intermediate metabolism of skeletal cells. (mdpi.com)
Pulsed Magnetic Field Stimuli Can Promote Chondrogenic Differentiation of Superparamagnetic Iron Oxide Nanoparticles-Labeled Mesenchymal Stem Cells in Rats. (bioss.com.cn)
TCEA3 promotes differentiation of C2C12 cells via an Annexin A1‐mediated transforming growth factor‐β signaling pathway. (bioss.com.cn)
In Drosophila with depleted RACK1 in all muscle cells or, specifically, in SC lineage resulted in a delayed recovery of skeletal muscle after physical damage as well as the low presence of active SC in the wound area. (sdbonline.org)
Shortly after their dorsal specification, neural crest cells undergo an epithelial-to-mesenchymal transition, migrate, and finally, upon arrival at their destination, they give rise to a variety of cell types. (biomedcentral.com)
Good needle aspiration cytology Smear showed diffusely cellular stroma, bedding of epithelial cells and multiple bare nuclei with no atypia. (columbiagypsy.net)
The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. (peprotech.com)
Determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells.The expected ED 50 for this effect is 1.0-3.0 ng/ml. (peprotech.com)
Mitofusin-2 Restrains Hepatic Stellate Cells' Proliferation via PI3K/Akt Signaling Pathway and Inhibits Liver Fibrosis in Rats. (peprotech.com)
It promotes cellular proliferation and provides a supporting structure to which cells or cell lysates in culture dishes adhere. (lookformedical.com)
Previously, we have identified the profound cystine addiction of renal cell carcinoma (1), breast cancer cells (2, 3), and ovarian cancer cells (4). (duke.edu)
Red blood cells (RBC) are responsible for oxygen delivery to muscles during vigorous exercise. (duke.edu)
The primary action of 1,25-(OH)2 D3 is to promote gut absorption of calcium by stimulating formation of calcium-binding protein within the intestinal epithelial cells. (medscape.com)
Receptors1
activation and proliferation appear to be stimulated by cytokines released by activated osteoblasts and osteocytes or by differentiation of immature osteoclast precursors that possess parathyroid hormone (PTH) and vitamin D receptors. (medscape.com)
Promotes2
Preliminary results indicate that it also promotes brown adipocyte differentiation in vitro. (met-vasc.com)
The dynamics of RACK1 levels in isolated adult SC of mice, i.e., progressively high during differentiation and low compared to proliferating conditions, and RACK1 silencing indicated that RACK1 promotes both the formation of myotubes and the accretion of nascent myotubes. (sdbonline.org)
Genetic1
Genetic differentiation among autochthonous and cosmopolitan goat breeds based on information from microsatellite markers - a preliminary study. (krakow.pl)
Dorsal1
These include a notochord, segmented trunk muscles, and a dorsal nerve cord. (biomedcentral.com)
Glial1
A remarkable proportion of the new neural crest genes encode soluble ligands that control neural crest precursor specification into each cell lineage, including pigmented, neural, glial, and skeletal derivatives. (biomedcentral.com)
Survival4
The outcome of LPA signaling is dependent on cellular context and impacts on biological processes such as wound healing, differentiation, neurogenesis, and survival, to name a few [ 4 ]. (hindawi.com)
Environmental cues found throughout neural crest migratory routes play a fundamental role not only in instructing the precursor's differentiation into particular phenotypes, but also in controlling their proliferation and survival [ 7 ]. (biomedcentral.com)
The ppGpp binds to the transcription factor DksA and RNA polymerase to orchestrate extensive transcriptional changes that repress proliferation and promote stress survival (8, 9). (duke.edu)
Therefore, MESH1 knockdown leads to both stress survival and proliferation arrest, two cardinal features highly reminiscent of the bacterial stringent response. (duke.edu)
Transition1
FOXD3 suppresses epithelial-mesenchymal transition through direct transcriptional promotion of SMAD7 in esophageal squamous cell carcinoma. (bioss.com.cn)
Phenotypes1
Now, we are investigating how MESH1 removal leads to proliferation of arrests and anti-tumor phenotypes. (duke.edu)
Inhibition2
Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium. (academicinfluence.com)
Inhibition of renal fibrosis with a human CXCL9-derived glycosaminoglycan-binding peptide. (peprotech.com)
Vitro1
We have used this product for in vitro smooth muscle cell differentiation from human IPSCs for more than 4 years, which contributes to several high quality publication such as Circulation, ATVB, and Nature Comm. (peprotech.com)
Prostate2
2021. "A comprehensive urine proteome database generated from patients with various renal conditions and prostate cancer. (pnnl.gov)
Runt-related transcription factor 2 (RUNX2) belongs to the RUNX family (including RUNX1-3) and has been recognized as a key modulator and master transcription factor for osteogenesis, as well as prostate and skeletal development ( 4 - 7 ). (spandidos-publications.com)
Cytoplasm1
In the concluding phase of differentiation, the white blood cell rich cytoplasm appears bright and exhibits cross-striation. (wikipedia.org)
Growth2
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism. (academicinfluence.com)
RACK1 was expressed transiently in the skeletal muscle of post-natal mice, being abundant in the early phase of muscle growth and almost disappearing in adult mature fibers. (sdbonline.org)
Primitive1
Rapidly growing breast mass could hardly ever become metastasis GS-1101 kinase activity assay from rhabdomyosarcoma, leukaemia, lymphoma, primitive neuroectodermal tumours, Ewing sarcoma, malignant melanoma and renal cell carcinoma.3 However, the size of such masses is not usually as gigantic as in our individual. (columbiagypsy.net)
Genes1
Linkage and comparative mapping studies indicate that the transferred chromosome segment contains a number of candidate genes for hypertension, including genes encoding a brain dopamine receptor and a renal epithelial potassium channel. (jci.org)
Characteristics2
Each stage of differentiation exhibits unique and distinguishable histological characteristics. (wikipedia.org)
In response to mito- pendence between the key mecha- gens, cell proliferation is triggered by nistic characteristics. (who.int)
Abundant1
In skeletal muscle, isoform 1 is more abundant than isoform 2. (affbiotech.cn)
Progression3
For instance, RUNX2 is involved in the progression of various tumor types, such as osteosarcoma, renal cell carcinoma, gastric cancer and breast cancer ( 15 - 20 ). (spandidos-publications.com)
After acute injury in muscle of both mouse and the fruit fly Drosophila melanogaster (used as alternative in vivo model) this study found that RACK1 accumulated in regenerating fibers while it declined with the progression of repair process. (sdbonline.org)
Collectively, this study provides the first evidence that transient levels of the evolutionarily conserved factor RACK1 are critical for adult SC activation and proper skeletal muscle regeneration, favoring the efficient progression of SC from a committed to a fully differentiated state. (sdbonline.org)
Bone2
First, osteoclasts are activated to digest formed bone, and second, proliferation of osteoclasts occurs. (medscape.com)
In bone, vitamin D may play a synergistic role with parathyroid hormone (PTH) in stimulating osteoclast proliferation and bone resorption. (medscape.com)
Occurs1
Activation and eosinophilic infiltration of the superficial airway occurs, rather than of airway smooth muscle. (medscape.com)
Expression1
Meanwhile, the dysregulation and alteration of RUNX2 expression or activity may result in arteriosclerosis, skeletal dysplasia (e.g., cleidocranial dysplasia) and tumorigenesis ( 4 , 12 - 14 ). (spandidos-publications.com)
Activation1
These results also suggest the coupling of RACK1 to muscle unfolded protein response during SC activation. (sdbonline.org)
Clinical1
In clinical settings, the emergence of post-chemotherapy rhabdomyoblast differentiation in cases of pediatric embryonal rhabdomyosarcoma is an encouraging prognosis, as it potentially signifies the tumor's increased response to the provided therapy. (wikipedia.org)
Fundamental1
The detection of rhabdomyoblasts is fundamental in the diagnosis of rhabdomyosarcomas, but rhabdomyoblast differentiation can be detected in several pediatric neoplasms. (wikipedia.org)