Epithelial mucin 1. Medical search. Frequent questions

MUC16 is more than twice as long as MUC1 and MUC4 and contains about 22,000 amino acids, making it the largest membrane-associated mucin. (wikipedia.org)
Epithelial immunospot (EPISPOT) is an antibody-based method for quantification of live CTCs by detection of CTCs which are capable of secreting proteins such as cathepsin D, MUC1 and CK19. (medscape.com)
For facs or microscopy Alexa 1 conjugate.Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-MUC1 has a very high photo stability. (ningbobio.com)
In the current study we show that designer glycopeptides containing the Thomsen-Freidenreich (TF) antigen (β-Gal-[1→3]-α-GalNAc- O -serine) are immunogenic in vivo and generate TF-specific CTL capable of recognizing a variety of tumor cells in vitro including a MUC1-expressing tumor. (silverchair.com)
The transmembrane mucin MUC1 co- localizes with CFTR. (healthdrugpdf.com)
Mucin 1 ( MUC1 ) is a kind of cell surface mucins and is abundant in mucosal tissues, especially in normal gastric epithelial cells [ 9 ]. (biomedcentral.com)
Cancer antigen 27-29 (or CA 27-29) is an epitope of a large transmembrane mucin glycoprotein named MUC1 that is expressed on the cell surfaces of most glandular epithelia. (medscape.com)
1, 7] The MUC1 protein and its overexpression may be causally related to cancer invasion and metastasis. (medscape.com)
As tumor cells shed the MUC1 protein into the bloodstream, CA 27-29 is recognized by a single monoclonal antibody, which recognizes a 20 amino-acid sequence in the mucin core. (medscape.com)
these data showed that sustained abnormal MUC1 induction accompanies failing epithelial repair, chronic inflammation and kidney fibrosis. (cusabio.com)
The crystal structure of the mucin monoclonal antibody SM3 complexed with a 13 amino acid MUC1 mucin peptide was determined. (wisconsin.edu)
Membrane bound mucins MUC1 and MUC3 appear to be associated with the development of gastric carcinoma. (bmj.com)
Aberrant (upregulated) expression of the MUC1 mucin has been seen in breast carcinomas and other neoplasms, such as colon and pancreatic cancers. (bmj.com)
1, 2 Most studies of MUC1 expression in breast carcinomas have shown that increased membrane MUC1 mucin expression on the apical cell surface is associated with a better prognosis (reviewed in Rahn and colleagues 2 ), whereas circumferential staining in tumour cell cytoplasm is associated with a worse prognosis. (bmj.com)

Di Gioia D, Blankenburg I, Nagel D, Heinemann V, Stieber P. Tumor markers in the early detection of tumor recurrence in breast cancer patients: CA 125, CYFRA 21-1, HER2 shed antigen, LDH and CRP in combination with CEA and CA 15-3. (scielo.br)
1] This protein, also known as polymorphic epithelial mucin or epithelial membrane antigen, has a large extracellular region, a transmembrane sequence, and a cytosolic domain. (medscape.com)

The effects of serum on mucin (MUC-1) expression were observed in cultured conjunctival epithelial cells in vitro. (bmj.com)
Finally, ODE-induced Muc5ac levels were enhanced in MyD88-deficient airway epithelial cells in vitro. (cdc.gov)
Finally, some of these proteins were found to be adherent to intestinal epithelial cells in vitro. (escholarship.org)

MUC-16 is a member of the mucin family glycoproteins. (wikipedia.org)
BACKGROUND AND AIMS: Trefoil factor family (TFF) peptides and the chromosome 11p15.5 mucin glycoproteins are expressed and secreted in a site specific fashion along the length of the gastrointestinal tract. (embl.de)
The role of mucins, high molecular weight glycoproteins that comprise the mucus, in the pathophysiology of cystic fibrosis is currently being investigated. (healthdrugpdf.com)

16-membered) on MUC5AC and MUC2 gene expression and secretion from human airway epithelial cells. (karger.com)
MyD88 controls airway epithelial Muc5ac expression during TLR activation conditions from agricultur al organic dust exposure. (cdc.gov)
Expression and production of respiratory mucins, MUC5AC and MUC5B, were analyzed by real-time PCR, agarose gel electrophoresis, and western blotting. (manchester.ac.uk)
The findings of this study indicate that prostaglandin E 2 (PGE 2 ) induces MUC5AC gene expression and mucin secretion via the EP4 receptor in cultured normal human nasal epithelial cells. (elsevierpure.com)
This study aimed to investigate the MUC5AC mucin gene and mucin secretion by PGE 2 and its receptors in cultured normal human nasal epithelial cells. (elsevierpure.com)
Total mucin and MUC5AC mucin levels were measured using an immuno-dot blotting assay. (elsevierpure.com)
PGE 2 increased only MUC5AC gene expression and MUC5AC mucin, but not expression of other gel-forming mucin genes. (elsevierpure.com)
An EP2 receptor antagonist (AH 6809) did not suppress the PGE 2 -induced MUC5AC gene expression or MUC5AC mucin. (elsevierpure.com)
However, an EP4 receptor antagonist (AH23848) significantly suppressed the level of PGE 2 -induced MUC5AC gene expression and MUC5AC mucin. (elsevierpure.com)
The findings of this study indicate that prostaglandin E 2 (PGE2) induces MUC5AC gene expression and mucin secretion via the EP4 receptor in cultured normal human nasal epithelial cells. (elsevierpure.com)
PGE2 increased only MUC5AC gene expression and MUC5AC mucin, but not expression of other gel-forming mucin genes. (elsevierpure.com)
An EP2 receptor antagonist (AH 6809) did not suppress the PGE2-induced MUC5AC gene expression or MUC5AC mucin. (elsevierpure.com)
However, an EP4 receptor antagonist (AH23848) significantly suppressed the level of PGE2-induced MUC5AC gene expression and MUC5AC mucin. (elsevierpure.com)

Mucin-16 (MUC-16) also known as Ovarian cancer-related tumor marker CA125 is a protein that in humans is encoded by the MUC16 gene. (wikipedia.org)
After the incubation period, the cells are removed and secreted protein 'spots' are detected by immunological techniques and counted, where each spot corresponds to 1 live CTC (Figure 4). (medscape.com)
Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE KINASE. (uams.edu)
The effect of dexamethasone on mRNA and protein synthesis of lipocortins (LCT) 1, 2 and 5 has been investigated in U-937 cells. (shengsci.com)
Sequence-specific binding property of Arabidopsis thaliana telomeric DNA binding protein 1 (AtTBP1). (shengsci.com)
The most abundant mucus protein in the mucosal layer is mucin 2 (MUC2). (layerorigin.com)
Hepatitis A virus cellular receptor 1 homolog, HAVcr-1, Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucin domain-containing protein 1, TIMD-1, T cell membrane protein 1, T-cell immunoglobulin mucin receptor 1, TIM-1. (prospecbio.com)
The Mucin-Like Protein OSM-8 Negatively Regul. (prolekarniky.cz)
Our studies are the first to show that an extracellular mucin-like protein plays an important role in animal osmoregulation in a manner that requires the activity of a novel transmembrane protein. (prolekarniky.cz)

It was concluded that circulating epithelial cells may be present in patients with benign inflammatory colon which were detectable by CTC assays. (medscape.com)

Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. (embl.de)
Evidence for coexpression of mucins and trefoil peptides has been suggested in numerous gastrointestinal mucosal pathologies. (embl.de)
We tested the hypothesis that individual trefoil peptides are uniquely localised with specific mucins in the UACL and normal gastrointestinal epithelia. (embl.de)
Colocalisation of mucins and trefoil peptides was demonstrated by immunofluorescent colabelling in UACL and normal gastrointestinal epithelia. (embl.de)
Coordinated localisation of trefoil peptides and mucins in UACL and normal gastrointestinal epithelia suggests they may assist each others' functions in protection and repair of gastrointestinal mucosa. (embl.de)
Trefoil factor family (TFF)-domain peptides 1-3 are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues. (shengsci.com)
Trefoil factor family 2 ( TFF2 ), a member of secreted peptides, is also expressed in gastric mucosa and triggers cell migration signaling to promote epithelial repair [ 14 , 15 ]. (biomedcentral.com)

Distinct pathways of cell migration and antiapoptotic response to epithelial injury: structure-function analysis of human intestinal trefoil factor. (embl.de)
The trefoil peptide intestinal trefoil factor (ITF) plays a critical role in the protection of colonic mucosa and is essential to restitution after epithelial damage. (embl.de)
And a major one is the intestinal epithelial barrier, also commonly known as the gut lining. (layerorigin.com)
What does the intestinal epithelial barrier look like? (layerorigin.com)
The next layer is the epithelial layer, a single, continuous layer of intestinal epithelial cells or IECs that are tightly attached to one another at junction proteins. (layerorigin.com)
The intestinal epithelial barrier also has in important role in implementing an immune response with the gut-associated lymphoid tissue (GALT), through the initiation of pro- and anti-inflammatory signals [vi] . (layerorigin.com)
The prebiotic inulin induced other family 1 binding proteins with affinity for intestinal glycans. (escholarship.org)

Kim YD, Cho JS, Kim HS, Song SH: Effect of macrolide on the interleukin-1 β-mediated MUC2/5AC genes expression and mucin secretion in human airway epithelial cells. (karger.com)
Furthermore, the enhanced airway mucins in the MyD88- deficient mice were not due to defective secretion, as the mucin secretory capacity of MyD88-KO mice remained intact. (cdc.gov)
1-3 Under stimulation, the ostia may secrete a thick mucoid material, and, in rare occasions, purulent secretion, as a result of secondary infection of the gland. (bvsalud.org)

Shimizu T, Shimizu S: Azithromycin inhibits mucus hypersecretion from airway epithelial cells. (karger.com)
Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by the hypersecretion of mucus by specialized epithelial cells in the lungs. (healthdrugpdf.com)
Alongside the mucus layer, the epithelial cell layer makes up the physical barrier within the gut [iv] . (layerorigin.com)
The fluid consists of mucus with muciphages (macrophages with engulfed mucin), as demonstrated by mucicarmine staining, and other inflammatory cells. (medscape.com)

ODE primarily increased mucin (Muc)5ac levels relative to Muc5b. (cdc.gov)
Conclusion Expression of SOX2 and MUC5B and lack of SPDEF in atypically differentiated cells of bronchiolised distal airspaces are consistent with abnormal programming of airway epithelial cells in IPF. (bmj.com)
Activation of abnormal respiratory epithelial differentiation programs may contribute to the expression of MUC5B and bronchiolisation of the distal lung, a salient feature of IPF. (bmj.com)

in this study, CIC with a separation and distortion of epithelial cells specificity of 94% and sensitivity of 93%, and losses of mucin-secreting goblet cells, was used [14]. (who.int)

To evaluate the effect of multipurpose contact lens care solutions (MPSs) on membrane-associated mucins (Muc 1 & 16) expressions in the cornea using SV40 transformed Human corneal epithelial Cells (HCET) and Rat cornea tissue sections. (arvojournals.org)
Human corneal epithelial cells were treated with different concentrations of MPS-A, MPS-B, MPS-C, MPS-D, and MPS-E: 100% treatment for 30 minutes and 10% treatment for 24 hours. (arvojournals.org)
2009 To address the mechanism by which Muc4 distribution is definitely controlled in corneal epithelia we have examined proteosomal degradation of Muc4/SMC in stratified corneal epithelial cell ethnicities using immunoblotting and confocal microscopy for the analysis of Muc4/SMC together with proteosome inhibitors and N-glycosylation inhibitors to alter proteosome degradation. (healthanddietblog.info)
These combined results clearly display QX 314 chloride that proteosome degradation and TGF-β play tasks in regulating the levels of Muc4/SMC in the corneal epithelial layers. (healthanddietblog.info)
Rat Corneal Epithelium Main Ethnicities Fisher 344 rats were used throughout this study in accordance with National QX 314 chloride Institutes of Health Guidebook for the Care and Use of Laboratory Animals and corneal epithelial cell tradition was performed as explained earlier (Lomako et al. (healthanddietblog.info)

The expression of mucin 16 has been shown to be altered in dry eye, cystic fibrosis, and several types of cancers. (wikipedia.org)
This appears to be due to the ability of the C-terminal domain of MUC16 to facilitate signaling that leads to a decrease in the expression of E-cadherin and increase the expression of N-cadherin and vimentin, which are expression patterns consistent with epithelial-mesenchymal transition. (wikipedia.org)
METHODS: Expression of mucin genes in the UACL from small bowel tissue of patients with Crohn's disease was detected by in situ hybridisation, and localisation of the products by immunohistochemistry. (embl.de)
CONCLUSIONS: The UACL has a unique profile of mucin gene expression. (embl.de)
Dexamethasone induces the expression of the mRNA of lipocortin 1 and 2 and the release of lipocortin 1 and 5 in differentiated, but not undifferentiated U-937 cells. (shengsci.com)
Gene expression clustering studies in ovarian cancer have shown that the mesenchymal subtype, enriched in an EMT-related gene signature, has a worse prognosis and survival compared to other subtypes [ 1 ] . (encyclopedia.pub)
Thus, a high expression of inhibitory immune checkpoint molecules such as PD-1, PD-L1, CTLA-4, OX40L, and PD-L2 was observed in tumors with the most mesenchymal EMT scores. (encyclopedia.pub)
After treatment with PGE 2 and/or PGE 2 antagonist, gel-forming mucin mRNA expression was determined by reverse transcription-polymerase chain reaction. (elsevierpure.com)
After treatment with PGE2 and/or PGE2 antagonist, gel-forming mucin mRNA expression was determined by reverse transcription-polymerase chain reaction. (elsevierpure.com)
Growth on HMO induced the expression of specific binding proteins that import HMO isomers, but also bind blood group and mucin oligosaccharides, suggesting coregulated transport mechanisms. (escholarship.org)
Genetic studies of osmoregulation in yeast have identified mucin-like proteins as critical regulators of osmosensitive signaling and gene expression. (prolekarniky.cz)
Several studies have reported conflicting and inconclusive results concerning the clinical relevance of mucin expression in gastric carcinoma. (bmj.com)
This study investigated the correlations between aberrant expression of mucins in gastric carcinoma and patient clinicopathological features. (bmj.com)

The present study demonstrates that AZM and MDM suppress the synthesis of mucin and TNF-α from human airway epithelial cells. (karger.com)
Cigana C, Assael BM, Melotti P: Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells. (karger.com)
Results In IPF, the bronchiolised and enlarged distal airspaces stained for SOX2 are consistent with epithelial differentiation characteristic of conducting airway epithelium. (bmj.com)
Title : Effect of Epithelial-Specific MyD88 Signaling Pathway on Airway Inflammatory Response to Organic Dust Exposure Personal Author(s) : Johnson, Amber N.;Dickinson, John;Nelson, Amy;Gaurav, Rohit;Kudrna, Katrina;Evans, Scott E.;Janike, Katherine;Wyatt, Todd A.;Poole, Jill A. (cdc.gov)

In oncology, Poseida has a broad pipeline of allogeneic CAR-T cell therapy product candidates for both solid and liquid tumors, including P-MUC1C-ALLO1, which is in Phase 1 development for the treatment of multiple solid tumor indications. (biotechnology.report)
About P-MUC1C-ALLO1 P-MUC1C-ALLO1 is an allogeneic CAR-T product candidate in Phase 1 development for multiple solid tumor indications. (biotechnology.report)
Gastric cancer (GC) is a common malignant tumor originating from gastric mucosa epithelial cells, and its onset is relatively insidious. (frontiersin.org)
Carcinoma cells that undergo an epithelial-mesenchymal transition (EMT) and display a predominantly mesenchymal phenotype (hereafter EMT tumor cells) are associated with immune exclusion and immune deviation in the tumor microenvironment (TME). (encyclopedia.pub)
In a study of lung adenocarcinoma [ 4 ] , EMT markers were associated with enhanced tumor infiltration of CD4 + Foxp3 + Tregs and upregulation of inhibitory immune checkpoint molecules such as programmed cell death (PD)-ligand (L) 1, PD-L2, TIM-3, B7-H3, and CTLA-4. (encyclopedia.pub)
An association between EMT tumor cells (mesenchymal and hybrid epithelial-mesenchymal phenotypes) and increased numbers of infiltrating PD-1 + cells was also observed in another study in patients with adenocarcinoma of the lung [ 6 ] . (encyclopedia.pub)

CA 27-29 represents a sequence of mucins on the extracellular region of this glycoprotein. (medscape.com)

Since MUC16 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. (wikipedia.org)

Methods: Primary human bronchial epithelial (HBE) cells cultured at air-liquid interface were treated with exogenous TGF-β1, TGF-β2, and/or a Th2 cytokine, interleukin (IL)-13. (manchester.ac.uk)
A number of different methods, clini- clinical forms of VAD is 1:10 [5]. (who.int)

Immunostaining for components of those pathways and mucins were performed on lung tissue obtained from patients with IPF (n=20), chronic obstructive pulmonary disease (n=13), idiopathic pulmonary artery hypertension (n=5) and from organ donors (n=6). (bmj.com)
A transmembrane mucin that is found in a broad variety of epithelial tissue. (uams.edu)
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Small Breast Epithelial Mucin (SBEM) in serum, plasma, tissue homogenates, saliva and other biological fluids. (wildpalm.net)
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Small Breast Epithelial Mucin (SBEM) in samples from Serum, plasma, tissue homogenates, saliva and other biological fluids with no significant corss-reactivity with analogues from other species. (wildpalm.net)

Induces the differentiation of human PSC-derived alveolar epithelial type II (AETII) to AETI cells (Ghaedi et al. (stemcell.com)
1-5 Accumulated knowledge in the past decade has demonstrated the importance of tear components such as epidermal growth factor (EGF) and vitamin A in the regulation of proliferation, differentiation, and maturation of the ocular surface epithelium. (bmj.com)
In general, mucins have the unique function of protecting and lubricating epithelial surfaces, but in recent years they have also been implicated in additional diverse roles, such as growth, fetal development, epithelial renewal and differentiation, epithelial integrity, carcinogenesis, and metastasis. (bmj.com)
Rat Muc4, a homologue of human MUC4, has been extensively studied in mammary gland tumours and has been shown to play an important role in epithelial growth, cell differentiation, cell-cell adhesion, metastasis, and tumour apoptosis. (bmj.com)

A noninvasive (noninfiltrating) carcinoma of the breast characterized by a proliferation of malignant epithelial cells confined to the mammary ducts or lobules, without light-microscopy evidence of invasion through the basement membrane into the surrounding stroma. (lookformedical.com)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)

Here, we show that mutations in the Caenorhabditis elegans mucin-like gene osm-8 specifically disrupt osmoregulatory physiological processes. (prolekarniky.cz)

The additive effect of human serum for cultured conjunctival epithelial cells showed significant MUC-1 upregulation on the cell surface. (bmj.com)
The present study was designed to determine the efficacy and safety of autologous serum application in the treatment of epithelial disorders associated with SS dry eye. (bmj.com)
Studied predictive use of mucin 1 (KL-6) serum level as a biomarker in development of bronchopulmonary dysplasia in preterm infants. (cusabio.com)
The inclusion criteria were (abnormal serum levels of CEA or breast cancer [1-3]. (who.int)

Hepatitis A virus cellular receptor 1 (HAVCR1) is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. (prospecbio.com)

Experimental lung research , 39 (1), 39-47. (manchester.ac.uk)

Mucin 16 is a membrane associated mucin that possesses a single transmembrane domain. (wikipedia.org)
Membrane-associated mucins are one of the major components of the ocular surface that play a vital role in the maintenance of the ocular surface integrity. (arvojournals.org)
Membrane-associated mucins (Muc 1 and Muc 16) expressions were subsequently analyzed by Western blot. (arvojournals.org)
Cornea sections and lysates were prepared from the eyes of the treated rats and used for the immunohistochemistry and Western blot analysis of membrane-associated mucins expressions. (arvojournals.org)
Western blot was also used to analyze the effect of 0.1% macrogolglycerol hydroxystearate (HCO), 0.1% poloxamer, 0.1% poloxamine, 5 pm polyaminopropyl biguanide (PHMB), 0.05% boric acid, and 0.1% boric acid, common MPSs ingredients, on membrane-associated mucins (Muc 1 and Muc 16 ) expressions in HCET after 24 hours treatment. (arvojournals.org)
Western blot results showed that MPSs containing boric acid down-regulate membrane-associated mucins in the cornea while MPSs without boric acid had no effect on membrane-associated mucins. (arvojournals.org)
Immunohistochemistry analysis of membrane-associated mucins expressions confirmed the results of the Western blot analysis. (arvojournals.org)

Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. (ningbobio.com)

We investigated the presence of aluminium (Al) in human colon cancer samples and its potential association with biological processes involved in cancer progression, such as epithelial to mesenchymal transition (EMT) and cell death. (bvsalud.org)
Epithelial-Mesenchymal Transition Phenotype and Immune System" Encyclopedia , https://encyclopedia.pub/entry/22115 (accessed November 30, 2023). (encyclopedia.pub)

Synthesized peptide derived from the C-terminal region of Human Mucin 1. (cusabio.com)

Puede desempeñar un papel en la regulación de la adhesión celular y en la señalización de la superficie celular mediante el RECEPTOR ERBB-2. (bvsalud.org)

MUC4 is a heterodimeric membrane mucin composed of a mucin subunit ASGP-1 (MUC4α) and a transmembrane subunit ASGP-2 (MUC4β) which has been implicated in the safety of epithelial cell surfaces. (healthanddietblog.info)
Intro Rat Muc4/SMC (sialomucin complex) is definitely a heterodimeric membrane mucin composed of a mucin subunit ASGP-1 (called MUC4α in human being) and a transmembrane subunit ASGP-2 (MUC4β in human being) (Sherblom and Carraway 1980 Carraway et al. (healthanddietblog.info)
namely, MUC3, MUC4, MUC12, MUC13, and the recently described mucin MUC17, which share a C-terminal structural domain that consists of two or three epithelial growth factor (EGF)-like regions, a transmembrane segment, and a short cytoplasmic tail. (bmj.com)

2002 The mucin in the rat is definitely translated from a 9 kb transcript (Sheng et al. (healthanddietblog.info)
2002 Several functions have been attributed to membrane mucins. (healthanddietblog.info)
2002 The membrane mucin may lengthen more than a micron from your cell surface. (healthanddietblog.info)
2002 To avoid this problem cells must have stringent mechanisms for controlling membrane mucin production. (healthanddietblog.info)

Confluent NCI-H292 human mucoepidermoid airways epithelial cells were pretreated with AZM or MDM for 2 h and then stimulated with 200 nmol/l phorbol 12-myristate 13-acetate (PMA) for 8 h. (karger.com)

Epithelial mucins can be classified into two distinct families: secretory (gel forming) and membrane bound. (bmj.com)

1] CA 27-29 levels tend to remain relatively stable over time in benign conditions. (medscape.com)

Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients. (uams.edu)

All mucins contain a tandem repeat domain that has repeating amino acid sequences high in serine, threonine and proline. (wikipedia.org)

Unfortunately, patients are already in the terminal stage at this time, and the cancer cells have already invaded the surrounding organs or metastasized far away, which leads to the loss of the curative chance for most patients ( 1 ). (frontiersin.org)

Multipurpose solutions' composition should be clinically controlled because Mucins play a very important role in the ocular surface integrity maintenance and the tear film stability. (arvojournals.org)

With the use of an established model, C57BL/6J wild-type (WT) and global MyD88 knockout (KO) mice were treated with intranasal inhalation of ODE or saline, daily for 1 wk. (cdc.gov)

Anatomy1

Diseases1

Chemicals and Drugs11

MUC114

Antigen2

Cells in vitro3

Glycoproteins3

Muc5ac13

Protein9

Circulating epithelial cells1

Peptides7

Intestinal7

Secretion3

Mucus4

Muc5b3

Specificity1

Corneal epithelial5

Expression13

Airway4

Tumor6

Extracellular1

Apical1

METHODS2

Tissue4

Differentiation4

Carcinoma2

Gene1

Serum4

Hepatitis A Virus Cellular Recept1

Lung1

Membrane-associated7

Antibody1

Mesenchymal2

Peptide1

Receptor1

Muc43

20024

Human1

Secretory1

Benign1

Mutations1

Amino acid1

Cancer1

Clinically1

Mice1