Many antigens associated with sweat gland neoplasms, including S-100 protein, CA72.4, gross cystic disease fluid protein 15 (GCDFP-15), and carcinoembryonic antigen (CEA), are absent in sebaceous tumors. (medscape.com)
Pilar and sebaceous neoplasms share a common expression for both high and low molecular weight cytokeratin that is not seen in most eccrine or apocrine tumors, pointing to similar cellular differentiation patterns of hair and sebaceous structures. (medscape.com)
Proteins2
however, rabbit antibodies raised against the recombinant proteins encoded by the gene of mouse bullous pemphigoid antigen 2 (BP180) are capable of inducing blisters in newborn mice in a complement-dependent manner. (medscape.com)
Chimeric antigen receptors (CAR) recognize specific proteins on the surface of tumor cells. (msdmanuals.com)
Antibody1
This antibody has a high affinity for CEA and shows no detectable reactivity to nonspecific cross-reacting antigen (NCA), biliary glycoprotein (BGP) and human polymorphonuclear leucocytes. (samatashkhis.com)
Basement membrane2
Whereas the pemphigus subset of diseases is mediated by autoantibodies that target the extracellular skin components that link one epidermal cell to another, the pemphigoid subset is mediated by autoantibodies that target the extracellular skin components that link the skin basement membrane components either to the lowermost layer of epidermal cells or to the dermal components. (medscape.com)
The term fibroma is inappropriate because the neoplasm exhibits defined histologic features that differ from those of fibromas and may express malignant behavior. (medscape.com)
The third case presented with a hemorrhagic, rapidly enlarging gingival mass with a histologic appearance of an undifferentiated neoplasm. (utmb.edu)
Mucous2
The clinical impression was that of an exophytic squamous cell carcinoma arising from the dentoalveolar mucous membrane. (peertechzpublications.org)
A group of autoimmune blistering diseases affecting primarily the mucous membranes is termed mucous membrane pemphigoid (MMP) (also termed cicatricial pemphigoid ). (medscape.com)
Malignant4
The term sebaceous neoplasm includes benign and malignant tumors with different degrees of sebaceous differentiation. (medscape.com)
Nonmesotheliomatous cancers of the pleura include an assortment of malignant neoplasms that primarily or secondarily involve pleura. (medscape.com)
By definition, pseudomesotheliomatous carcinoma refers to an epithelial neoplasm that secondarily involves the pleura and encases the lung, thereby simulating the radiologic and macroscopic appearance of malignant mesothelioma. (medscape.com)
Synovial sarcoma is a malignant soft-tissue neoplasm that most commonly affects the extremities near to, but not in continuity with, large joints. (medscape.com)
Malignancy2
When patients with numerous sebaceous adenomas and/or other neoplasms with sebaceous differentiation have an associated internal malignancy, the clinical condition is known as Muir-Torre syndrome , a subtype of familial nonpolyposis gut carcinoma syndrome, or Lynch syndrome. (medscape.com)
These results suggest that plasma cell malignancy is another AIDS-associated neoplasm. (utmb.edu)
Diagnosis2
It has a non-debatable contribution to the diagnosis of hematolymphoid neoplasm as well as in minimal residual disease. (ijpmonline.org)
Therefore, the term sebaceous neoplasm is necessary to include these complex skin adnexal tumors with varying degrees of sebaceous differentiation. (medscape.com)
Furthermore, the architectural features of sebaceous tumors resemble those of pilar neoplasms, and not those of sweat gland tumors. (medscape.com)
Benign smooth muscle tumors, or leiomyomas, are common, well-circumscribed neoplasms that can arise from smooth muscle cells anywhere in the body, but are encountered most commonly in the uterus [1]. (peertechzpublications.org)
Spindle2
Synovial sarcomas encompass both biphasic (epithelial and spindle cell components) and monophasic (purely spindle cell) variants. (medscape.com)
Various cell lineages such as the epithelial glandular cells and the stromal spindle cells are involved. (ijpmonline.org)
Cells4
SFTs of the pleura are localized mesenchymal neoplasms composed of fibroblastlike cells believed to arise from the subpleural connective tissue. (medscape.com)
Combination of analysis of fluorescence labeling and light scatter properties of cells allows rapid and better determination of target cell antigens. (ijpmonline.org)
Tumor Antigens Many tumor cells produce antigens, which may be released in the bloodstream or remain on the cell surface. (msdmanuals.com)
Concomitant use of interferon enhances the expression of major histocompatibility complex (MHC) antigens and TAAs on tumor cells, thereby augmenting the killing of tumor cells by the infused effector cells. (msdmanuals.com)
Expression1
Expression of keratin 5 as a distinctive feature of epithelial and biphasic mesotheliomas. (novodiax.com)
Positive1
Immunoperoxidase studies revealed positive staining only for epithelial membrane antigen. (utmb.edu)
Cell1
Flow cytometric detection of intracellular antigens has become a standard method in establishing proper leukemic cell lineage affiliation. (ijpmonline.org)
Skin2
Skin lesions containing benign sebaceous gland proliferation (eg, sebaceous hyperplasia), congenital hamartomas (eg, nevus sebaceus), and lesions with ectopic sebaceous structures (eg, Fordyce spot, Montgomery tubercles) are generally not considered to be true sebaceous neoplasms. (medscape.com)
[ 1 ] True sebaceous neoplasms are relatively rare, while sebaceous hyperplasia is a frequent finding in individuals with chronically sun-exposed skin. (medscape.com)
CD3261
Epithelial cell adhesion molecule (EpCAM, also designated as TACSTD1 or CD326) is a cell surface glycoprotein, which is localized on the basolateral membrane seen in majority of normal epithelial tissues or neoplasms derived from epithelia ( 1 ). (iiarjournals.org)
Cellules1
Les lymphocytes T pourraient être responsables de la régulation de la prolifération, et donc de la croissance, des cellules épithéliales malignes dans les carcinomes basocellulaires. (who.int)
EpCAM2
Background/Aim: Epithelial cell adhesion molecule (EpCAM) is expressed in various types of cancer, including breast cancer, and is correlated with metastasis, invasion, therapeutic resistance and prognosis. (iiarjournals.org)
The wide expression of EpCAM on tumor cells suggests that it is a tumor-associated antigen, and it could be of special interest for innovative immunotherapies. (iiarjournals.org)
Tumor cells2
Tumor cells co-express epithelial, mesenchymal and neuronal markers and are thought to originate from a mesothelial or submesothelial progenitor cell with the potential to undergo multilineage differentiation. (sarcomahelp.org)
It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. (nih.gov)
Intestinal2
In contrast, MUC2 is rarely detectable in aggressive pancreatic tumours, but is commonly expressed in intraductal papillary mucinous neoplasms (IPMNs), which are rare, indolent tumours, in intestinal IPMNs, and in indolent colloid carcinomas. (bmj.com)
También se expresa en la superficie de las células tumorales epiteliales y del ADENOCARCINOMA. (bvsalud.org)
Lymphocytes2
It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. (nih.gov)
https://nhtsa.gov/Driving-Safety/Aggressive-Driving) HN - 2019 MH - Alefacept UI - D000077944 MN - D12.776.124.486.485.114.619.393.131 MN - D12.776.124.790.651.114.619.393.131 MN - D12.776.377.715.548.114.619.393.131 MN - D12.776.395.550.34.500 MN - D12.776.543.550.158.500 MN - D12.776.828.300.100 MS - A recombinant human fusion protein of LFA-3 antigen and immunoglobulin IGG1 that binds to CD2 ANTIGENS on memory T-LYMPHOCYTES, preventing their activation and proliferation. (nih.gov)
Protein1
Those coupled to membrane depolarization or intracellular release of calcium include the receptor-mediated activation of cytotoxic functions in granulocytes and the synaptic potentiation of protein kinase activation. (lookformedical.com)
Differentiation3
[ 7 ] Tumors with pure sarcomatoid morphology due to overgrowth of the RCC components are classified as SRCC if evidence of epithelial differentiation can be demonstrated through immunohistochemical or ultrastructural analysis. (medscape.com)
This theory has been confirmed by genetic studies such as analysis of X-chromosome inactivation patterns, which indicated a clonal origin for both the epithelial and sarcomatoid components of CCRCCs with sarcomatoid differentiation. (medscape.com)
A la I Conferència i Taller Internacional sobre diferenciació dels antígens leucocitaris humans , celebrada a París el 1982, fou aprovada la terminologia CD (cúmul o grup de diferenciació [18] o cluster of differentiation en anglès). (wikipedia.org)
Mice1
We have studied the transgenic mouse strain, Tyrp-1-TAg, to try to gain insight into possible molecular mechanisms common to pigmented ocular neoplasms occurring spontaneously in the eyes of these mice and human choroidal melanoma. (molvis.org)
Cases1
SRCCs were originally considered to be carcinosarcomas or to be renal sarcomas in cases in which the sarcomatous component had overgrown all epithelial (carcinomatous) components. (medscape.com)
Patients1
Carbohydrate antigen elevated in patients with tumors of the breast, ovary, lung, and prostate as well as other disorders. (nih.gov)