• These findings lead us to conclude that CAP37 is definitely an crucial regulator of corneal epithelial cell migration and mediates its effects through PKCd. (amparinhibitor.com)
  • Fibroblast progenitor cells migrate to the endocardial region during cardiogenesis, and the migration of ventricular fibroblasts to the ischemically damaged region of the infarcted adult heart is a seminal event of reparative fibrosis. (bvsalud.org)
  • The intermediate filament protein nestin is implicated in cell migration and expression identified in a subpopulation of scar-derived myofibroblasts. (bvsalud.org)
  • The neonatal rat heart contains a distinct subpopulation of nestin-immunoreactive Tcf21/WT1(+) fibroblasts refractory to cell cycle reentry, and the intermediate filament protein may preferentially facilitate ventricular fibroblast migration during physiological/pathological remodeling.NEW & NOTEWORTHY Tcf21/WT1(+)-fibroblast progenitor cells of the embryonic mouse heart predominantly express the intermediate filament protein nestin. (bvsalud.org)
  • METHODS: We studied a panel of putative CSC surface markers (ALDH1A1, ABCG2, CD44v7/8, CD44v10, CD133, CD271, and Nestin) in 40 established melanoma cell lines and four early-passage melanoma strains by flow cytometry. (bvsalud.org)
  • Its D5 Receptor Gene ID induced expression in corneal epithelial cells in response to infection suggests a role in host defense and inflammation.5,12 The role of endogenously induced CAP37 in facilitating the healing of corneal wounds remains unknown and would be the focus of future studies. (amparinhibitor.com)
  • Nestin-expressing NNVFbs exhibited a unique phenotype as the subpopulation was refractory to cell cycle reentry in response to selective stimuli. (bvsalud.org)
  • However, the expression of these markers by cells in healthy skin sections, normal differentiated melanocytes, and fibroblasts revealed that differentiated non-malignant cells also expressed CSC markers indicating that they lack of specificity for CSCs. (bvsalud.org)
  • The objective of this study was to elucidate the signaling pathway through which cationic antimicrobial protein of 37 kDa (CAP37) mediates human corneal epithelial cell (HCEC) chemotaxis. (amparinhibitor.com)
  • The present study tested the hypothesis that fibroblast progenitor cells express nestin, and the intermediate filament protein drives the migratory phenotype of ventricular fibroblasts. (bvsalud.org)
  • Inhibition of the migration of treated cells across the wound area was detected. (bvsalud.org)
  • Taken together, our data show that the anticancer effects of tridecylpyrrolidine analogues in colon cancer cells are mediated by antiproliferative activity, the induction of both extrinsic and intrinsic apoptotic pathways and the inhibition of cell migration. (bvsalud.org)
  • The capacity for production of migration inhibitory factor was assessed by the agarose droplet cell migration inhibition assay, using peritoneal exudate cells and a CVB3(m) cell lysate or KCl extracted antigens from heart tissues of CVB3(m)-inoculated mice. (nih.gov)
  • 14. Regulation of apical Cl- conductance and basolateral K+ conductances by phorbol esters in HT-29cl.19A cells. (nih.gov)
  • In addition, DAG-sensitive PKC isoforms can be activated pharmacologically using phorbol esters (Table 1) (47, 55). (pancreapedia.org)
  • 4. In-vitro transfer of nitazoxanide across the intestinal epithelial barrier. (nih.gov)
  • Cell viability will be determined via MTT and epithelial barrier integrity will be determined via TEER. (edu.au)
  • Cellular distributions of the ERM proteins in MDCK epithelial cells: regulation by growth and cytoskeletal integrity. (embl-heidelberg.de)
  • 6. Regulation of iron uptake and transport by transferrin in Caco-2 cells, an intestinal cell line. (nih.gov)
  • 17. Regulation of copper uptake and transport in intestinal cell monolayers by acute and chronic copper exposure. (nih.gov)
  • Molecules that protect: the defense of neurons and other cells. (jci.org)
  • Chymase in granules released from degranulated rat serosal mast cells, i.e., in granule remnants, proteolyzes human high density lipoprotein3 (HDL3), and so reduces its ability to induce cholesterol efflux from macrophage foam cells in vitro. (jci.org)
  • In this study we found that remnant chymase, by proteolyzing human serum and human aortic intimal fluid, prevents these two physiologic fluids from effectively inducing cholesterol efflux from cultured macrophage foam cells. (jci.org)
  • The data are compatible with the notion that an immune deviation mechanism, thought to be controlled through a mechanism requiring suppressor cell activity which inhibits macrophage activation in ts 1 survivors, protects these mice from induction of myocarditis. (nih.gov)
  • We found that systemic administration of DEX attenuated cognitive deficits by performing the Y maze and novel object recognition tests and increased DCX+, SOX2+, Ki67+, and BrdU+NeuN+/NeuN+ cell numbers in the dentate gyrus (DG) region of SD mice by using immunofluorescence, western blotting, and BrdU staining. (bvsalud.org)
  • DEX did not reverse the decrease in DCX+, SOX2+, or Ki67+ cell numbers in SD mice after administration of the α2A-adrenoceptor antagonist BRL-44408. (bvsalud.org)
  • Cell-mediated immunity in ts 1 survivors was compared with that of normal mice after challenge with CVB3(m). (nih.gov)
  • Inactive Sendai virus grown in LLC-MK(2) cells, which possessed an uncleaved precursor glycoprotein, F, and was noninfectious to tissue culture cells, neither grew nor caused pathological changes in the lung of mice. (nih.gov)
  • 13. Interaction of human lactoferrin with the rat liver. (nih.gov)
  • We examined hepatic lipase metabolism in normal, 6-wk-old CRF rats, CRF-PTX (parathyroidectomized) rats, and CRF and normal rats treated with verapamil (CRF-V, normal-V) using liver homogenate, hepatic cell culture for 8 h, and in vitro liver perfusion. (jci.org)
  • Genomic DNA samples (0.25?g) collected from various cells treated with siControl or siADAR1-1 RNAs for 72?h were examined by dot blot assay using the Cimigenol-3-O-alpha-L-arabinoside S9.6 antibody. (skinmicrobiomecongressca.com)
  • L'Faqihi, and A.L. internalization of anti-TNF antibody/tmTNF complexes by dendritic cells has been shown. (skinmicrobiomecongressca.com)
  • The results suggest two mechanisms by which ts 1 survivors exhibit resistance to CVB3(m) induction of myocarditis, namely, the rapid production of high-titered anti-CVB3(m) neutralizing antibody in response to CVB3(m) inoculation and altered cell-mediated immune responses against CVB3(m) induced viral or novel cellular antigens. (nih.gov)
  • The highly homologous ERM (ezrin/radixin/moesin) proteins, molecular cross-linkers which connect the cell membrane with the underlying cytoskeleton, have molecular weights of 81, 80 and 78 kDa respectively. (embl-heidelberg.de)
  • We present data which shows significant variation in the molecular weight and presence of multiple forms of ERM proteins in different cell lines, such that specific antibodies to each protein are essential for unambiguous detection. (embl-heidelberg.de)
  • 3. Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1. (nih.gov)
  • In the present study, we investigated the antiproliferative and pro-apoptotic effects of (2S,3S,4R)-2-tridecylpyrrolidine-3,4-diol hydrochloride on colon cancer cells (Caco-2 and HCT116). (bvsalud.org)
  • Culture of hepatic cells for 8 h was associated with an increase in hepatic lipase activity but the increment in CRF rats was significantly (P (jci.org)
  • 1. Apical-to-basolateral transepithelial transport of human lactoferrin in the intestinal cell line HT-29cl.19A. (nih.gov)
  • 10. Caco-2 cell line: a system for studying intestinal iron transport across epithelial cell monolayers. (nih.gov)
  • 19. Dipeptide transporters in apical and basolateral membranes of the human intestinal cell line Caco-2. (nih.gov)
  • Preliminary experiments from our lab have shown that Bakuchiol to be more toxic than Psoralen to the hepatocyte model cell line HepG2. (edu.au)
  • Given its use in cosmetics, the effect of Bakuchiol on toxicity in an epithelial cell line will be tested as well. (edu.au)
  • 2. Recombinant human lactoferrin and iron transport across Caco-2 monolayers: effect of heat treatment on the binding to cells. (nih.gov)
  • 7. Interactions of bismuth with human lactoferrin and recognition of the Bi(III)-lactoferrin complex by intestinal cells. (nih.gov)
  • 11. Effects of iron-unsaturated human lactoferrin on hydrogen peroxide-induced oxidative damage in intestinal epithelial cells. (nih.gov)
  • The technique outlined below is characterized by high sensitivity and specificity and has been successfully applied to human bladder cancer cell lines. (bvsalud.org)
  • Degranulated mast cells are present in human fatty streaks. (jci.org)
  • Both parathyroid hormone (PTH)-(1-84) and 1-34 inhibited the production of hepatic lipase in cultured cells from normal, CRF-PTX, CRF-V, and normal-V rats. (jci.org)
  • This study examined whether the highly conserved cytoplasmic tail of podocalyxin also contributes to the unique organization of podocytes by interacting with the cytoskeletal network found in their cell bodies and foot processes. (embl-heidelberg.de)