Epileptiform activity. Medical search. Frequent questions

[ 7 ] Epileptiform patterns include spike and sharp wave discharges, either alone or accompanied by slow waves, occurring singly or in bursts lasting at most a few seconds (see image below). (medscape.com)
Our findings have implications for how the route of Ca(2+) entry and subsequent Ca(2+) dynamics can influence network excitability during epileptiform discharges. (ox.ac.uk)
Differentiate epilepsy with epileptiform discharges during slow-wave sleep and the Landau-Kleffner syndrome from related conditions. (medscape.org)
Activity in the precuneus gates generalizes spike-and-wave discharges: An example of the interaction of resting state brain activity and epileptiform events. (mpg.de)
Neonatal Seizure Disorders Neonatal seizures are abnormal electrical discharges in the central nervous system of neonates and usually manifest as stereotyped muscular activity or autonomic changes. (msdmanuals.com)
Researchers say listening to Mozart can lead to a decrease in epileptiform discharges, the brain waves that can cause seizures. (sky.com)
Researchers at the Hospital St Anne and CEITEC Masaryk University in the Czech Republic found that listening to Mozart's Sonata For Two Pianos K448 reduced epileptiform discharges (EDs) - the electrical brain waves associated with epilepsy and which can cause seizures. (sky.com)
in the men, there was an increase of epileptiform discharges. (sky.com)
Continuous epileptiform discharges during sleep as an evolutionary pattern in patients with congenital Zika virus syndrome. (bvsalud.org)
mean age = 50 months) with confirmed CZVS were analyzed, considering the background, interictal, and ictal epileptiform discharges. (bvsalud.org)
Continuous (or almost continuous) epileptiform discharges during non- rapid eye movement sleep were identified in 22 (40%) patients . (bvsalud.org)
In CZVS, continuous (or almost continuous) epileptiform discharges during sleep emerge as a pattern after the second year of life . (bvsalud.org)
Subcortical calcifications and multifocal epileptiform discharges in infancy are associated with this pattern. (bvsalud.org)

[ 6 ] These 2 conditions are not currently considered epileptic encephalopathies, but there is increasing evidence that epilepsy or epileptiform activity may contribute to encephalopathy in a subset of cases. (medscape.com)
In contrast, the term epileptiform encephalopathies describes those conditions in which the interictal epileptiform EEG abnormalities may be more prominent than the clinical seizures. (medscape.com)
I call some of these epileptiform encephalopathies. (medscape.org)

other epilepsy syndromes, such as some cases of benign focal childhood epilepsy with centro-temporal spikes (benign rolandic epilepsy) and autism with epileptiform EEG abnormalities, may also fit under this rubric. (medscape.com)
In clinical practice, the ability to distinguish between epileptiform activity and an epileptic disorder may be challenging, as variability may be seen within each epilepsy syndrome and within a given child over time. (medscape.com)
In all three epilepsy models, we found that longer delays and/or higher concentrations of convulsants were necessary to generate spontaneous epileptiform activity in Prnp0/0 mice. (ox.ac.uk)
Epilepsy is a neurological disorder characterised by an increased likelihood of recurrent seizures, which in turn are characterised by transient, pathological episodes of hypersynchronised neural activity resulting in a variety of behavioural symptoms. (springer.com)
Our chapter introduces some of the key concepts of epilepsy from a clinical perspective, before describing some of the classical approaches to modelling brain activity across multiple levels of description. (springer.com)
The American Epilepsy Society designates this educational activity for a maximum of 1.5 hours in category 1 credit toward the AMA Physician's Recognition Award. (medscape.org)
At this time, it remains unclear how much of the dysfunction seen in these disorders is due to epileptiform EEG activity and how much is due to the underlying cause of the epilepsy syndrome. (medscape.com)
Here, we report the localization of the epileptiform activity among the many cortical tubers in a 4-year-old patient with TSC-related refractory epilepsy undergoing magnetoencephalography (MEG), electroencephalography (EEG), and diffusion tensor imaging (DTI). (harvard.edu)
Increased excitatory synaptic activity and local connectivity of hippocampal CA1 pyramidal cells in rats with kainate-induced epilepsy. (hopkinsmedicine.org)
Repetitive perforant-path stimulation induces epileptiform bursts in minislices of dentate gyrus from rats with kainate-induced epilepsy. (hopkinsmedicine.org)
While previous studies have shown associations between BBB dysfunction and seizure activity in epilepsy, there is a paucity of investigations exploring the underlying molecular mechanisms that drive microvascular dysfunction in the condition. (tcd.ie)
The team compared the effects of listening to two classical pieces on epilepsy and on brain activity. (sky.com)
Historically, when we monitored this activity in the epilepsy unit, we could only monitor for 10 or 14 days. (medscape.com)

In CA3 neurons of disinhibited hippocampal slice cultures the slow afterhyperpolarisation, following spontaneous epileptiform burst events, was confirmed to be Ca(2+) dependent and mediated by K(+) ions. (ox.ac.uk)
We recorded spontaneous synchronized epileptiform bursts from hippocampal slices from guinea pig using an array of 16 extracellular electrodes placed over the stratum pyramidale of CA2 and CA3. (nih.gov)
These models simulate the spontaneous activity of interconnected brain areas, just as in the real brain. (utwente.nl)

The ILAE defined an epileptic encephalopathy as a condition in which "the epileptiform EEG abnormalities themselves are believed to contribute to a progressive disturbance in cerebral function. (medscape.com)
Later in 2010, researchers defined epileptic encephalopathy as a condition where the epileptic activity itself may contribute to severe cognitive and behavioral impairments above and beyond what might be expected from the underlying pathology alone (e.g., cortical malformation), and that these can worsen over time. (medscape.com)
Note that the term epileptic encephalopathy may refer to conditions with severe and frequent ictal EEG activity (actual seizures) as a more prominent component. (medscape.com)
Chatrian et al in their 1974 glossary of EEG terms defined the term epileptiform to describe distinct waves or complexes, distinguishable from the background activity, which resemble the waveforms recorded in a proportion of human subjects suffering from an epileptic disorder. (medscape.com)
Inherent in the notion of an epileptic encephalopathy is that limiting or suppressing EEG ictal and/or interictal activity may improve cognitive and behavioral outcome. (medscape.com)
On one hand, this relation can be concentrated in verifying the changes induced by epileptic condition on neurotransmitter synthesis, released content and receptor activity. (scielo.br)
These would be specific epileptic syndromes that are associated with frequent epileptiform activity on the electroencephalogram (EEG). (medscape.org)

Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro. (ox.ac.uk)
These results suggest that quinine suppresses extracellular potassium transients and ictal activity and modulates inter-ictal activity by limiting the firing rate of cells in a voltage-dependent manner. (ox.ac.uk)

However, in some cases, severe developmental regression may be seen in the context of few seizures but severe interictal epileptiform abnormalities, as in some cases of LKS). (medscape.com)
All had multiple epileptiform abnormalities and clinical or subclinical seizures. (umn.edu)
If I am talking to another healthcare professional, I will tell them that I monitor brainwaves of patients and look for any seizure-like activity or any abnormalities. (aset.org)

We also map the location of pathological activity and use the data to locate the source of seizures and the pathways for their propagation in each individual patient's brain. (stanford.edu)
It could be that patients who have more epileptiform activity hours before their seizures may feel something. (medscape.com)

The effect of quinine on pyramidal cell intrinsic properties, extracellular potassium transients, and epileptiform activity was studied in vitro using the rat hippocampal slice preparation. (ox.ac.uk)

Focal slowing or polymorphic delta activity in area of involved blood vessel. (studystack.com)
Most common finding is focal 4-7 Hz theta with sh/sp focal activity and focal delta activity. (studystack.com)
Focal slowing or sharp activity can also be seen in pts with certain types. (studystack.com)
Focal lesions early in life may secondarily affect other sites in the brain, and hypsarrhythmia may represent this abnormal activity arising from multiple brain sites. (medscape.com)

MEG is superior to EEG in the localization of interictal epileptiform activity. (bvsalud.org)

These results indicate that CA2 is a unique region which must possess unusual cellular and/or synaptic connectivity properties which result in a decreased threshold for initiation of epileptiform activity. (nih.gov)
Graphene electrodes record high-frequency bursting activity and slow synaptic potentials that are hard to resolve by multicellular calcium imaging. (nature.com)

Both clinical and preclinical evidence implicate an episode of prolonged seizure activity [status epilepticus (SE)] as one cause of TLE in humans. (jneurosci.org)

Modulates epileptiform synchronization in rat brain slices. (tocris.com)

And how consistently reproducible must the patterns of activity in a putative assembly be before it can be considered a bona fide assembly? (degruyter.com)

EEG shows diffuse slowing with excessive delta and theta activity. (studystack.com)
Electroencephalogram showed diffuse slow waves but no epileptiform activity. (psychiatrist.com)

reduces in vitro epileptiform synchronization. (tocris.com)

The combined use of microelectrode array technology and 4-aminopyridine-induced chemical stimulation for investigating network-level nociceptive activity in the spinal cord dorsal horn is outlined. (jove.com)

We retrospectively studied patients who had undergone orthotopic liver transplantation and who also had electroencephalography to determine whether epileptiform changes were associated with a poor neurological outcome. (umn.edu)

This transparent electrode technology may pave the way for high spatio-temporal resolution electro-optic mapping of the dynamic neuronal activity. (nature.com)
Cell assemblies and central pattern generators (CPGs) are related types of neuronal networks: both consist of interacting groups of neurons whose collective activities lead to defined functional outputs. (degruyter.com)

Galanin, found primarily within the central nervous system (limbic system, piriform cortex, and amygdala), plays a role in the reduction of long term potentiation (LTP), regulating consumption habits, as well as inhibiting seizure activity. (wikipedia.org)

The methodology presented enables dorsal horn circuit activity to be investigated at a macroscopic regional level of resolution. (jove.com)
This method helps bridge the gap in our understanding of how the activity of specific cell types and small micro circuits influence large populations of neurons to subsequently shape the output of the dorsal horn behavior responses and ultimately the pain experience. (jove.com)

Threshold for epileptiform activity is elevated in prion knockout mice. (ox.ac.uk)

Theta activity and some delta sharp waves become present (mostly in the temporal lobe). (studystack.com)

Data are insufficient to recommend treatment for the sole purpose of minimizing interictal epileptiform activity at this time, especially when the clinical symptoms of the epileptiform activity on the patient are unclear. (medscape.com)
The generators of interictal activity were localized using both EEG and MEG with equivalent current dipole (ECD) and minimum norm estimation (MNE) methods according to the current clinical standards. (harvard.edu)
Vanja Holm, Hugo Moser, and Alan Percy [ 6 ] attended the 1984 meeting which saw the first effort in development of consensus criteria for diagnosis and created the first broad scale efforts worldwide in clinical and research activity [ 7 ]. (hindawi.com)

Essential oils and the constituents in them exhibit different pharmacological activities, such as antinociceptive, anxiolytic-like, and anticonvulsant effects. (mdpi.com)
You may observe that nodes 3 and 4 exhibit epileptiform activity simultaneously. (utwente.nl)

The GDPSP/C was dependent on the availability of bicarbonate, but not on interstitial or intrapyramidal carbonic anhydrase activity. (jneurosci.org)

2001 ), which can be activated by tyrosine kinase activity upstream through signal transduction (Oldenhof et al. (frontiersin.org)

Medscape encourages you to complete the Activity Evaluation to provide feedback for future programming. (medscape.org)

This activity is designed for neurologists, internists, pharmacists, nurses, and other allied healthcare professionals who wish to enhance their knowledge and understanding of antiepileptic therapies. (medscape.org)

Metal microelectrode arrays commonly used for recording neural activity cannot be used for such purposes, as they block the field of view, generate optical shadows and are prone to producing light-induced artefacts in the recordings. (nature.com)

The new connection dramatically increases the amount of epileptiform activity. (utwente.nl)

We study brain activity from the very early sensory input to very late decision making in even social or emotional domains. (stanford.edu)
Whenever a possible seizure is recorded, it will stimulate the brain [to disrupt the] abnormal brain activity. (medscape.com)

N-methyl D-aspartate receptor activation contributed to the depolarisations associated with the epileptiform activity but Ca(2+) entry via this route did not contribute to the activation of the post-burst afterhyperpolarisation. (ox.ac.uk)

DSM-IV-TR lists motor immobility, excessive purposeless motor activity, extreme negativism or mutism, peculiarities of voluntary movements, echolalia, and/or echopraxia as the signs of catatonia. (psychiatrist.com)

Roux-en-Y gastric bypass surgery progressively alters radiologic measures of hypothalamic inflammation in obese patients. (mpg.de)
Epileptiform activity was seen in electroencephalograms of 14 of the patients who died (11 from the autopsy group) and in 2 of those who remained alive. (umn.edu)
Epileptiform activity in the electroencephalograms of patients who had undergone orthotopic liver transplantation indicates a poor prognosis. (umn.edu)
In 20 (90.1%) patients , the pattern was symmetrical, with an anterior predominance of the epileptiform activity. (bvsalud.org)

10yo+, reduction in abn activity but more slow background. (studystack.com)

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. (medscape.org)

The EEG will show polymorphic delta activity with no fast background due to cortical damage. (studystack.com)
May show high voltage beta activity and slowing with rhythmic polymorphic delta, triphasic activity, or even alpha coma, burst-suppression or ECS. (studystack.com)
Log in to save activities Your saved activities will show here so that you can easily access them whenever you're ready. (medscape.org)
If all is well, nodes 2, 3 and 4 will show no (or very little) epileptiform activity. (utwente.nl)
In this model, a seizure is a period in which three nodes show epileptiform activity simultaneously. (utwente.nl)

Each physician should claim only those hours of credit that he/she actually spent in the activity. (medscape.org)

Initially, slowing of alpha & increase of theta, followed by polymorphic delta activity & FIRDA. (studystack.com)

Ca(2+) entry through L-type Ca(2+) channels helps terminate epileptiform activity by activation of a Ca(2+) dependent afterhyperpolarisation in hippocampal CA3. (ox.ac.uk)
We suggest that Ca(2+) entry through L-type channels during an epileptiform event is selectively coupled to both apamin-sensitive and -insensitive Ca(2+) activated K(+) channels. (ox.ac.uk)

EEG showing an epileptiform beta frequency burst. (medscape.com)

EEG source analysis of epileptiform activity using a 1mm anisotropic hexahedra finite element head model. (mpg.de)

The device will then record and screen the EEG in the brain [for activity that could lead to a seizure]. (medscape.com)

That is, it more easily shows epileptiform activity. (utwente.nl)

References are publications that support the biological activity of the product. (tocris.com)

The magnification shows that this activity starts at node 3. (utwente.nl)

MNE and ECDs indicated epileptiform activity in the same areas. (harvard.edu)

Additional well-designed studies are needed to sufficiently quantify and correlate interictal epileptiform activity with neuropsychological and developmental measures. (medscape.com)

In this model, such a cycle inhibits the epileptiform activity. (utwente.nl)

However, observational and anecdotal evidence correlate the quantity of epileptiform activity with the degree of cognitive impairment. (medscape.com)

Anatomy18

Organisms6

Diseases10

Chemicals and Drugs36

Analytical, Diagnostic and Therapeutic Techniques and Equipment12

Psychiatry and Psychology1

Phenomena and Processes15

Disciplines and Occupations1

Health Care1

Discharges13

Encephalopathies3

Epilepsy13

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Seizures2

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Status epilepticus1

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