• Drug-resistant epilepsy is commonly diagnosed after several years of uncontrolled seizures, however, in most cases, it is evident much earlier. (wikipedia.org)
  • Next to indirect consequences like injuries from falls, accidents, drowning and impairment in daily life, seizure control is critical because uncontrolled seizures -specifically generalized tonic clonic seizures- can damage the brain and increase the risk for sudden unexpected death in epilepsy called SUDEP. (wikipedia.org)
  • In case of focal epilepsy, this evaluation provides crucial information to determine the area of brain where seizures begin. (wikipedia.org)
  • Temporal lobe epilepsy (TLE) was defined in 1985 by the International League Against Epilepsy (ILAE) as a condition characterized by recurrent, unprovoked seizures originating from the medial or lateral temporal lobe. (medscape.com)
  • In fact, 90% of patients with temporal interictal epileptiform abnormalities on their electroencephalograms (EEGs) have a history of seizures. (medscape.com)
  • Differences in paracingulate connectivity associated with epileptiform discharges and uncontrolled seizures in genetic generalized epilepsy. (uc.edu)
  • Comparisons of childhood trauma, alexithymia, and defensive styles in patients with psychogenic non-epileptic seizures vs. epilepsy: Implications for the etiology of conversion disorder. (uc.edu)
  • Patients with temporal lobe epilepsy (TLE) suffer from both uncontrollable seizures and cognition impairments. (jneuropsychiatry.org)
  • The key to the effectiveness of surgical treatment of childhood epilepsy is early surgical intervention, which leads to the control of epileptic seizures, correction of psychological and cognitive emotional disorders and improvement of quality of life. (theunj.org)
  • 2. Camfield P, Camfield C. Incidence, prevalence and aetiology of seizures and epilepsy in children. (theunj.org)
  • Outcome with respect to epileptic seizures Surgical Treatment of the Epilepsies. (theunj.org)
  • The current standard treatment for patients suffering from the most common form of uncontrolled seizures (temporal lobe epilepsy) is a temporal lobectomy, which involves removing the hippocampus and part of the anterior temporal lobe. (rfsuny.org)
  • Eating epilepsy (EE), where seizures are triggered by eating, is rare and has not been reported in the Gulf region. (elsevierpure.com)
  • Go to Epilepsy and Seizures, Neuroimaging in Epilepsy, Presurgical Evaluation of Medically Intractable Epilepsy, and Epilepsy Surgery for complete information on these topics. (medscape.com)
  • In 2001, the International League Against Epilepsy (ILAE) proposed a new classification scheme for outcome with respect to epileptic seizures after surgery. (medscape.com)
  • Learning that people with epilepsy can experience different types of seizures, which are often tricky to identify, the pieces began to come together - in hindsight, Garrett feels he had probably had the condition for a large portion of his life. (rchsd.org)
  • Activation of Fos during spontaneous hippocampal seizures in a model of temporal lobe epilepsy. (brain-knowledge-engine.org)
  • Moreover, recurrent uncontrolled seizures can evolve to status epileptics resulting in an increased risk of chronic epilepsy and poor prognosis. (biomedcentral.com)
  • These seizures initiated in the right lateral temporal area just above the solitary calcified lesion. (j-epilepsy.org)
  • A 42-year-old, right-handed male was admitted to the epilepsy clinic with a history of drug-resistant seizures since the age of 18. (j-epilepsy.org)
  • Electroencephalography and stereo-electroencephalography monitoring localized seizures to the right temporal lobe, allowing the patient to undergo right temporal lobectomy. (elsevierpure.com)
  • Other patients have non-lesional epilepsy, which means nothing appears on an MRI scan to indicate where the source of the seizures is located in the brain. (stlouischildrens.org)
  • Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology. (medscape.com)
  • Drug-resistant epilepsy (DRE), also known as refractory epilepsy, intractable epilepsy, or pharmacoresistant epilepsy, is diagnosed following a failure of adequate trials of two tolerated and appropriately chosen and used antiepileptic drugs (AEDs) (whether as monotherapies or in combination) to achieve sustained seizure freedom. (wikipedia.org)
  • Since the late 19th century, surgery has been accepted as a treatment for medically refractory epilepsy. (medscape.com)
  • Dr. Kim-McManus specializes in medically refractory epilepsy, meaning epilepsy that does not respond to medication, as well as clinical neurophysiology and epilepsy surgery. (rchsd.org)
  • Surgery could be a good treatment option for refractory epilepsy. (jepilia.org)
  • We examined the comprehensive white matter tract anatomy of the temporal lobe to gain an insight into the trans-middle temporal gyrus, a lateral approach which has been commonly used. (unifesp.br)
  • We reviewed the literature to compare the trans-middle temporal gyrus approach with other SeIAH techniques based on surgical outcomes. (unifesp.br)
  • Based on our anatomical study, in the transcortical amygdalohippocampectomy technique through the middle temporal gyrus the white matter pathways to be encountered. (unifesp.br)
  • The trans-middle temporal gyrus approach is commonly used in treatment of mesial temporal lobe epilepsy patients. (unifesp.br)
  • Trans-middle temporal gyrus selective amygdalohippocampectomy for medically intractable mesial temporal lobe epilepsy in adults: Seizure response rates, complications, and neuropsychological outcomes. (medscape.com)
  • Nearly all nuclei map to one of 125 robust cell types identified in the middle temporal gyrus. (bvsalud.org)
  • Magnetic resonance imaging revealed T2 signal hyperintensity and corresponding T1 signal hypointensity within the subcortical white matter of the right middle temporal gyrus. (elsevierpure.com)
  • MRI for evaluation of epilepsy often include T1 and T2 images with small voxel size, that are optimized to appreciate gray-white matter differentiation and oblique coronal images along the axis of hippocampus. (wikipedia.org)
  • The subpial dissection is performed along the lateral ventricular sulcus from the collateral eminence on lateral side and from the choroidal fissure on medial side by microdissector for en bloc resection of the hippocampus proper. (unifesp.br)
  • in temporal lobe epilepsy (tle) with evidence of hippocampal sclerosis (tle-mts) volumetric gray (gm) and white (wm) matter abnormalities are not restricted to the hippocampus but also are found in extrahippocampal structures. (brain-knowledge-engine.org)
  • Reorganization of CA3 area of the mouse hippocampus after pilocarpine induced temporal lobe epilepsy with special reference to the CA3-septum pathway. (brain-knowledge-engine.org)
  • we used the mouse pilocarpine model of temporal lobe epilepsy (tle), and injected iontophoretically the anterograde tracer phaseolus vulgaris leucoagglutinin (pha-l) into gliotic ca3, medial septum and the nucleus of diagonal band of broca, median raphe, and lateral supramammillary nuclei, or the retrograde tracer cholera toxin b subunit (ctb) into gliotic ca3 area of hippocampus . (brain-knowledge-engine.org)
  • our results suggest that complex mdr expression changes not only in the hippocampus but in the gph may play a role in aed pharmacoresistance in intractable epilepsy patients with mesial temporal lobe epilepsy (mtle) by altering the permeability of aeds across the blood-brain barrier (bbb). (brain-knowledge-engine.org)
  • A better anatomical and functional understanding of the structures of the temporal lobe is crucial for safer and more accurate surgery. (unifesp.br)
  • 7. Madaan P, Gupta A, Gulati S. Pediatric Epilepsy Surgery: Indications and Evaluation. (theunj.org)
  • 8. Dorfmüller G, Delalande O. Pediatric epilepsy surgery. (theunj.org)
  • 9. Jayakar A, Bolton J. Pediatric epilepsy surgery. (theunj.org)
  • Underrepresented Populations in Pediatric Epilepsy Surgery. (theunj.org)
  • 11. Galan FN, Beier AD, Sheth RD. Advances in Epilepsy Surgery. (theunj.org)
  • 12. Engel J Jr. The current place of epilepsy surgery. (theunj.org)
  • Pediatric Epilepsy Surgery: Preoperative Assessment and Surgical Treatment. (theunj.org)
  • Right now, researchers across the country are undertaking a groundbreaking clinical trial with the potential to help epilepsy patients without highly invasive and destructive brain surgery. (rfsuny.org)
  • Stone,J. (1989) Historical review of the Epilepsy Surgery Program at the University of Illinois medical Center: The Contributions of Bailey, Gibbs and Collaborators to the refinement of Anterior Temporal Lobectomy. (bvsalud.org)
  • When looking at the efficacy of epilepsy surgery, a patient's postsurgical seizure frequency is compared with his or her preoperative seizure frequency. (medscape.com)
  • In doing so, the assumption is made, based on the natural history of intractable epilepsy, that spontaneous remissions without surgery are infrequent. (medscape.com)
  • The concepts of his Stimulation study are interwoven with issues in Adverse effect, Epilepsy surgery and Depression. (research.com)
  • His Epilepsy surgery study integrates concerns from other disciplines, such as Radiology, Cortex and Medical emergency. (research.com)
  • Nathan B. Fountain usually deals with Temporal lobe and limits it to topics linked to Radiology and Randomized controlled trial, Epilepsy surgery and Anterior temporal lobectomy. (research.com)
  • Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. (research.com)
  • Epilepsy, Epilepsy surgery, Anesthesia, Clinical trial and Anterior temporal lobectomy are his primary areas of study. (research.com)
  • The various areas that he examines in his Anterior temporal lobectomy study include Randomized controlled trial, Surgery, Adverse effect and Quality of life. (research.com)
  • Of 132 patients who underwent epilepsy surgery for tumor-related epilepsy from 2006 to 2013, seven patients who underwent extraoperative ECoG were included in this study. (j-epilepsy.org)
  • Moreover, there has been some debate over the use of electrocorticography (ECoG) as an electrophysiological guide for tumor-related epilepsy surgery. (j-epilepsy.org)
  • 4 In contrast, another group reported equivalent rates of seizure control irrespective of the use of intraoperative ECoG, undermining the use of intraoperative ECoG in tumor-related epilepsy surgery. (j-epilepsy.org)
  • Methods Forty patients with MTLE (twenty-one without surgery and nineteen after anterior temporal lobectomy) as well as twenty healthy controls (HC) took part in the study. (bath.ac.uk)
  • These neurodiagnostic tests - video electroencephalogram and invasive stereoelectroencephalography, respectively - are often employed when first-line therapies for epilepsy are not fully controlling symptoms and patients are being evaluated for epilepsy surgery. (rchsd.org)
  • In collaboration with Shifteh Sattar, M.D. , medical director of epilepsy surgery at Rady Children's and associate clinical professor of neurosciences and pediatrics at UC San Diego School of Medicine, and Dr. Gonda, Garrett and his family weighed the options. (rchsd.org)
  • Dr. Nagahama is an assistant professor of neurosurgery at Rutgers - Robert Wood Johnson Medical School in New Brunswick, New Jersey, who specializes in epilepsy surgery and pediatric neurosurgery. (rutgers.edu)
  • He serves as Director of Pediatric Epilepsy Surgery. (rutgers.edu)
  • He subsequently completed a functional neurosurgery fellowship at UCLA Medical Center, with a focus on adult and pediatric epilepsy surgery under the mentorship of renowned epilepsy surgeons Dr. Itzhak Fried and Dr. Aria Fallah. (rutgers.edu)
  • He finally completed a pediatric neurosurgery fellowship at Children's Hospital Colorado, with a continued focus on pediatric epilepsy surgery. (rutgers.edu)
  • Dr. Nagahama specializes in epilepsy surgery as well as general pediatric neurosurgery. (rutgers.edu)
  • He utilizes all types of epilepsy surgery techniques, ranging from traditional resection/disconnection and neuromodulation surgery, such as lesionectomy, anterior temporal lobectomy, corpus callosotomy, functional hemispherotomy, and vagal nerve stimulation, to minimally invasive MRI-guided laser interstitial thermal therapy (LITT), to newer neuromodulation techniques, such as responsive neurostimulation (RNS) and deep brain stimulation (DBS). (rutgers.edu)
  • He also utilizes intracranial recording, both craniotomy for electrode placement and stereo-electroencephalography (stereo-EEG), to localize a seizure focus and guide epilepsy surgery. (rutgers.edu)
  • Dr. Nagahama has a research focus on epilepsy surgery outcome, in particular optimization of seizure and neuropsychological outcomes for epilepsy surgery. (rutgers.edu)
  • He has extensively published peer-reviewed articles in leading neurosurgical journals, particularly in the field of epilepsy surgery. (rutgers.edu)
  • A 42-year-old male with intractable epilepsy was admitted to the epilepsy clinic for invasive epilepsy surgery. (j-epilepsy.org)
  • No. Some epilepsy surgery hospitals do not have laser ablation systems, and not all pediatric neurosurgeons are trained in this technique. (brainrecoveryproject.org)
  • Presence of dual pathology in the temporal cortex that invisible on preoperative magnetic resonance imaging (MRI) in patients with pure mesial temporal low-grade tumors may put patients in risk of seizure continuation and tumor recurrence after resective surgery. (surgicalneurologyint.com)
  • 12 , 15 , 17 , 18 ] Depending on our own experience from epilepsy surgery and the current literature, we changed our surgical strategy to standard temporal resection as in temporal lobe epilepsy (TLE)-HS in patients with pure mesial temporal tumors, especially mesial temporal low-grade gliomas (LGG) during the past 10 years. (surgicalneurologyint.com)
  • Epilepsy surgery 4. (slideshare.net)
  • Laser ablation surgery is used to treat small lesions and epilepsy focal points. (stlouischildrens.org)
  • Approximately 30% of people with epilepsy have a drug-resistant form. (wikipedia.org)
  • One of the first steps in management of drug resistant epilepsy is confirming the diagnosis by EEG. (wikipedia.org)
  • Positron emission tomography scan using [18F]DG is often used in evaluation of drug resistant epilepsy as well. (wikipedia.org)
  • Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. (medscape.com)
  • to evaluate the effectiveness and safety of different operations in children with drug-resistant epilepsy. (theunj.org)
  • 91 children with drug-resistant epilepsy were enrolled in a retrospective study. (theunj.org)
  • In the multi-disciplinary epilepsy team, he works closely with experts in epileptology, neuroradiology, neuropsychology, and neurorehabilitation, in order to provide the individualized and optimum care for each patient with drug-resistant epilepsy. (rutgers.edu)
  • Antiepileptic drug-resistant rats differ from drug-responsive rats in hippocampal neurodegeneration and GABA(A) receptor ligand binding in a model of temporal lobe epilepsy. (brain-knowledge-engine.org)
  • Patients with drug-resistant (intractable) epilepsy who are 2 years of age or older may be eligible for the procedure. (stlouischildrens.org)
  • Disorders of the medial temporal lobe (MTL) adversely affect visual working memory (vWM) performance, including feature binding. (eneuro.org)
  • The role of the medial temporal lobe (MTL) in episodic memory is well established ( Squire, 2009 ). (eneuro.org)
  • Classical views of the medial temporal lobe (MTL) have established that it plays a crucial role in long-term memory (LTM). (ox.ac.uk)
  • In June 2018, his surgical team, who Kathy calls "amazing," completed ablation on his right medial temporal lobe. (rchsd.org)
  • Beach is a Professor of Neurology and the director of the Comprehensive Epilepsy Program. (rfsuny.org)
  • Dr. Berg is certified by the American Board of Psychiatry and Neurology, the subspecialty Boards of Clinical Neurophysiology and of Epilepsy, and the Americ. (rochester.edu)
  • He is a Fellow of the American Academy of Neurology (FAAN) and the American Epilepsy Society (FAES). (rochester.edu)
  • At the University of Rochester, Dr. Berg completed both a residency in Neurology and a fellowship in Epilepsy and then joined the Epilepsy Center faculty in 1992. (rochester.edu)
  • A video electroencephalography (EEG) monitoring study demonstrated frequent interictal epileptiform activity localized in the right temporal region. (j-epilepsy.org)
  • Temporal sampling is also limited, and the relatively short duration of routine interictal EEG recording is one reason why patients with epilepsy may not show interictal epileptiform discharge (IED) in the first EEG study. (bmj.com)
  • Brain 18 F-fludeoxyglucose positron emission tomography (FDG-PET) revealed hypo-metabolism in the right temporal region, including the mesial temporal area. (j-epilepsy.org)
  • Are low-grade gliomas of mesial temporal area alone? (surgicalneurologyint.com)
  • Temporal neocortex which appears normal on magnetic resonance imaging (MRI) may have pathological tissues in low-grade gliomas (LGG) of pure mesial temporal area. (surgicalneurologyint.com)
  • This prospective study included 10 patients who underwent surgical resection of temporal lobe for LGG of mesial temporal area. (surgicalneurologyint.com)
  • The temporal neocortex with normal appearance on MRI and mesial temporal area were resected separately, and histopathological diagnosis was performed. (surgicalneurologyint.com)
  • LGGs of the mesial temporal area were diagnosed with glioneuronal tumors in 7 (70%) and low-grade astrocytoma in 2 (20%) patients. (surgicalneurologyint.com)
  • Temporal lobe, particularly mesial temporal area, is the most epileptogenic lobe in the brain and any lesion in the temporal lobe may cause seizure because mainly of lower seizure threshold and if uncontrolled by medication, diagnosis of epilepsy becomes inevitable. (surgicalneurologyint.com)
  • 4 ] Another common pathological entity causing medically-intractable seizure is low-grade glioma, which especially prefers to locate temporal lobe, particularly mesial temporal area. (surgicalneurologyint.com)
  • Thus, any surgeon dealing with epilepsy has to consider both oncological and seizure outcome in patients with mesial temporal area low- grade tumors in planning surgical strategy. (surgicalneurologyint.com)
  • The surgical approach to mesial temporal area in case of a low-grade tumor is still challenging, and the data are very limited. (surgicalneurologyint.com)
  • Some investigators consider lesionectomy or resection of the tumor alone sufficient for seizure control[ 5 , 7 , 22 ] but others advocate additional resection of epileptogenic zone around the tumor or standard anterior temporal resection to optimize seizure control. (surgicalneurologyint.com)
  • Identification of lesions like focal cortical dysplasia, mesial temporal sclerosis, microencephalocele, heterotopia require thorough review of images by trained clinicians as the changes can be very subtle and easily missed if not specifically evaluated for. (wikipedia.org)
  • The development of brain imaging techniques for evaluating patients with intractable epilepsy has allowed for the identification of various structural brain lesions that may function as epileptogenic foci, such as those due to cortical dysplasia, vascular malformations, or tumors. (j-epilepsy.org)
  • Regarding the temporal cortex, gliosis and focal cortical dysplasia were found in 7 (70%) and 2 (20%) patients. (surgicalneurologyint.com)
  • Although unilateral anterior temporal lobectomy (ATL) is one of the most efficient treatments for TLE, the cognition outcomes are still under debate. (jneuropsychiatry.org)
  • We investigated whether the resection of interictal spikes recorded by ECoG is associated with more favorable surgical outcomes in tumor-related epilepsy. (j-epilepsy.org)
  • In these cases of tumor-related epilepsy, the extent of the resection of ECoG interictal spikes was not associated with postoperative seizure outcomes. (j-epilepsy.org)
  • Thus, anterior temporal resection should be performed to have satisfactory seizure and oncological outcomes. (surgicalneurologyint.com)
  • Although some surgeons utilize interictal spikes recorded via electrocorticography (ECoG) when planning extensive peritumoral resection in patients with tumor-related epilepsy, the association between interictal spikes and epileptogenesis has not been fully described. (j-epilepsy.org)
  • Basal temporal lobe was resected including parahippocampus as well as the hippocampal/parahippocampal resection was HDAC2 used posteriorly towards the tectal dish or much less aggressively if indicated by focal pathology or electrocorticography. (researchassistantresume.com)
  • Four sufferers underwent regular anteromedial TL resection at Emory School (2 prominent/2 non-dominant) which included the resection of lateral TL 3.5 cm in the temporal tip superiorly tied to the superior pia of the center temporal gyrus and inferiorly generally like the fusiform gyrus. (researchassistantresume.com)
  • Resection of the cortex may be required together with mesial temporal glioma for satisfactory seizure and oncological outcome. (surgicalneurologyint.com)
  • abstract = "Purpose The aim of the study was to examine if gaze and emotional expression, both highly self-relevant social signals, affect the recollection accuracy of perceived faces in patients with mesial temporal lobe epilepsy (MTLE). (bath.ac.uk)
  • Although less clinically tested and proven than temporal lobectomy, Garrett opted for laser ablation, which is minimally invasive and does not present the same risk of language and memory complications. (rchsd.org)
  • Generalmente, este procedimiento se usa para el tratamiento de la epilepsia temporal intratable (EPILEPSIA DEL LÓBULO TEMPORAL). (bvsalud.org)
  • The anterior temporal lobectomy (ATL) and selective amygdalohippocampectomy (SeIAH) have been used for surgical treatment of mesial temporal lobe epilepsy. (unifesp.br)
  • b) selective amygdalohippocampectomy … Naming and Recognition Testing Famous encounter naming and identification was assessed using the modified Iowa Famous Encounters Check.7 22 Common object naming was tested using the Boston Naming Check (BNT) 23 which include primarily man-made Dabrafenib (GSK2118436A) items and it is a commonly employed clinical check in the presurgical evaluation of epilepsy sufferers. (researchassistantresume.com)
  • Tumor-related epilepsy is pharmacoresistant in more than 50% of cases, and early surgical intervention is recommended. (j-epilepsy.org)
  • Here we demonstrate, in a sample of patients who have undergone anterior temporal lobectomy for the treatment of pharmacoresistant epilepsy, that the MTL additionally plays a specific, causal role in short-term memory (STM). (ox.ac.uk)
  • The neuropsychological and clinical data of 29 right and 24 left TLE patients who treated with unilateral ATL between February, 2014 and March, 2016 in a single epilepsy center were analyzed. (jneuropsychiatry.org)
  • He has been the Director and Chief of the University of Rochester Epilepsy Center from 2016 to 2023. (rochester.edu)
  • We review the available evidence for the use of neurostimulation to treat pediatric epilepsy, including vagus nerve stimulation (VNS), responsive neurostimulation (RNS), deep brain stimulation (DBS), chronic subthreshold cortical stimulation (CSCS), transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS). (mdpi.com)
  • Bioequivalence Between Generic and Branded Lamotrigine in People With Epilepsy: The EQUIGEN Randomized Clinical Trial. (uc.edu)
  • Generic-to-generic lamotrigine switches in people with epilepsy: the randomised controlled EQUIGEN trial. (uc.edu)
  • MRI of brain is the most common neuroimaging modality to be used in evaluation of epilepsy. (wikipedia.org)
  • The role of MEG in pre-surgical evaluation of epilepsy: current use and future directions. (theunj.org)
  • Garrett felt an improvement with his medication, but his epilepsy took a frightening turn in October 2017. (rchsd.org)
  • 3. Zack MM, Kobau R. National and State Estimates of the Numbers of Adults and Children with Active Epilepsy - United States, 2015. (theunj.org)
  • 4 , 8 , 14 ] The most common low-grade tumors in the temporal lobe are glioneuronal tumors, mainly represented by gangliogliomas (GG) and dysembryoplastic tumors (DNET), and are generally cause of focal epilepsies in children and young adults. (surgicalneurologyint.com)
  • This may be associated with autonomic phenomena and anxiety similar to those observed in the simple partial (focal aware) phase of a temporal lobe seizure. (medscape.com)
  • These wide ranges can be explained partly by diverse case selection and differences in clinical requirements for diagnosis of epilepsy in population studies of EEG specificity and sensitivity. (bmj.com)
  • Secondly, correlation between different EEG patterns and epilepsy varies, and only IED are associated with seizure disorders at a sufficiently high rate to be of clinical use. (bmj.com)
  • Some types of epileptiform phenomena-3 per second spike wave discharge, hypsarrhythmia, and generalised photoparoxysmal response-are strongly correlated with clinical epilepsy, whereas focal sharp waves in centro-temporal or occipital regions have moderate association with clinically active epilepsy. (bmj.com)
  • However, cognitive impairment is frequently noticed at the onset of epilepsy and antiepileptic drugs usually are not independently associated with cognitive dysfunction. (jepilia.org)
  • Dr. Nagahama completed a residency in neurosurgery at University of Iowa Hospitals and Clinics under the mentorship of Dr. Matthew Howard, a prominent epilepsy surgeon in the lineage of Dr. George Ojemann. (rutgers.edu)
  • He also performs brain surgeries for epilepsy, stroke, pituitary tumours, acoustic Schwannoma, cranioplasty and also treats pediatric neurosurgery. (medserg.com)
  • To address this issue, we compared performance in two tasks of 13 epilepsy patients, who had undergone a temporal lobectomy, and 15 healthy controls. (eneuro.org)
  • It is crucial to recognise that a normal EEG does not exclude epilepsy, as around 10% of patients with epilepsy never show epileptiform discharges. (bmj.com)
  • Some patients have lesional epilepsy, which means they have lesions or congenital (present from birth) malformations in the brain that can be identified on an MRI. (stlouischildrens.org)
  • The ROSA technology allows neurosurgeons and epileptologists (neurologists specializing in the treatment of epilepsy) to make 3-D maps of patients' brains that help determine where to place electrodes and assists with guiding the electrodes into place. (stlouischildrens.org)
  • We extended these efforts by assessing cell type variation across 75 adult individuals undergoing epilepsy and tumor surgeries. (bvsalud.org)