MesialSeizuresSeizureFrontal lobeHippocampal sclerosis2022Medial tempLeft temporal lobeChronic temporal lobe epiAtrophy20182020Medically2021CorticalPediatricCerebral CortexPsychiatricGeneticFamilialPatientsSurgical2023RadiosurgeryCognitionOnsetPathologyAmygdalaNeuroinflammationDistinguishBrainMolecularDevelopmentPublicationVolume
Mesial9
- Temporal lobe epilepsy is the most common focal onset epilepsy, and 80% of temporal lobe epilepsy is mesial (medial) temporal lobe epilepsy, temporal lobe epilepsy arising from the inner (medial) part of the temporal lobe that may involve the hippocampus, parahippocampal gyrus or amygdala. (wikipedia.org)
- In comparison to mesial temporal lobe seizures, lateral temporal lobe seizures are briefer duration seizures, occur with earlier loss of awareness, and are more likely become a focal to bilateral tonic-clonic seizure. (wikipedia.org)
- The major cognitive impairment in mesial temporal lobe epilepsy is a progressive memory impairment. (wikipedia.org)
- 71 Mesial temporal lobe epilepsy arising from the language dominant hemisphere impairs verbal memory, and mesial temporal lobe epilepsy arising from the language non-dominant hemisphere impairs nonverbal memory. (wikipedia.org)
- Trans-middle temporal gyrus selective amygdalohippocampectomy for medically intractable mesial temporal lobe epilepsy in adults: Seizure response rates, complications, and neuropsychological outcomes. (medscape.com)
- Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy. (medtronic.com)
- Mesial temporal lobe epilepsy (mTLE) associated with hippocampal sclerosis (mTLE-HS), a condition that can be detected by modern magnetic resonance imaging (MRI) techniques with a high sensitivity and specificity, is now the most common indication for epilepsy surgery. (hindawi.com)
- Recent studies showed that patients with mesial temporal lobe epilepsy (MTLE) had reduced anisotropy in the uncinate fasciculus, both ipsilateral and contralateral to the epileptic focus, and in addition, there is a significant correlation between changes of diffusivity and duration of epilepsy. (fapesp.br)
- Mesial temporal lobe epilepsy with hippocampal sclerosis is infrequently associated with neuronal autoantibodies. (cdc.gov)
Seizures11
- In the field of neurology, temporal lobe epilepsy is an enduring brain disorder that causes unprovoked seizures from the temporal lobe. (wikipedia.org)
- Seizure symptoms and behavior distinguish seizures arising from the medial temporal lobe from seizures arising from the lateral (neocortical) temporal lobe. (wikipedia.org)
- Temporal lobe epilepsy occurs from seizures arising within the temporal lobe. (wikipedia.org)
- The less common lateral temporal lobe or neocortical temporal lobe seizures arise from the outer (lateral) temporal lobe. (wikipedia.org)
- Lateral temporal lobe seizures arising from the temporal-parietal lobe junction may cause complex visual hallucinations. (wikipedia.org)
- Frontal lobe complex partial seizures (focal impaired awareness seizures) have certain distinct characteristics. (medscape.com)
- Kids with temporal lobe epilepsy have seizures that start in one of the temporal lobes of the brain . (teenshealth.org)
- The seizures in temporal lobe epilepsy are focal seizures . (teenshealth.org)
- What Do Seizures Look Like in Temporal Lobe Epilepsy? (teenshealth.org)
- These seizures are thought to begin in a part of the brain called the lateral temporal lobe. (medlineplus.gov)
- Familial temporal lobe epilepsy with aphasic seizures and linkage to chromosome 10q22-q24. (medlineplus.gov)
Seizure6
- A focal impaired awareness temporal lobe seizure occurs if a person becomes unaware during any part of the seizure. (wikipedia.org)
- A dystonic posture on one side of the body commonly indicates seizure onset from the opposite side of the brain e.g. right arm dystonic posture arising from a left temporal lobe seizure. (wikipedia.org)
- This may be associated with autonomic phenomena and anxiety similar to those observed in the simple partial (focal aware) phase of a temporal lobe seizure. (medscape.com)
- Seizure outcome after temporal lobectomy for temporal lobe epilepsy: a Kaplan-Meier survival analysis. (medscape.com)
- In some people, seizure activity may spread from the lateral temporal lobe to affect other regions of the brain. (medlineplus.gov)
- MRI analysis in temporal lobe epilepsy: Cortical thinning and white matter disruptions are related to side of seizure onset. (mpg.de)
Frontal lobe5
- But are temporal areas necessary for the development of the language areas in the frontal lobe, or do frontal language areas instead emerge independently? (biorxiv.org)
- However, her RH frontal language areas have no corresponding LH homotopic areas: no reliable response to language is detected on the lateral surface of EG's left frontal lobe. (biorxiv.org)
- The existence of temporal language areas therefore appears to be a prerequisite for the emergence of the language areas in the frontal lobe. (biorxiv.org)
- Probably the uncinate fasciculus plays a fundamental role in the propagation of temporal lobe epileptic activity to the frontal lobe. (fapesp.br)
- We analyzed 14 consecutive epilepsy patients with subdural electrodes implanted in the frontal lobe at Kyoto University Hospital. (sen.es)
Hippocampal sclerosis3
- Hippocampal sclerosis, brain tumor, traumatic brain injury, cerebral vascular malformation, neuronal migration disorders, infections such as encephalitis and meningitis, autoimmune disease (limbic encephalitis) and genetic disorders may cause temporal lobe epilepsy. (wikipedia.org)
- 1 In temporal lobe epilepsy (TLE), the most common pathology is hippocampal sclerosis (HS), 2 with the study of HS-TLE informing TLE's archetypal neuropsychological profile of anterograde memory impairment. (neurology.org)
- The objective of this study is to evaluate whether there is a relationship between temporal lobe epilepsy with and without hippocampal sclerosis, and fiber changes in the uncinate fasciculus, and response to treatment with antiepileptic drugs (AEDs), using the technique of diffusion tensor image (DTI). (fapesp.br)
20221
- 2022). Temporal lobe interictal spikes disrupt encoding and retrieval of verbal memory: A subregion analysis. (upenn.edu)
Medial temp1
- 2023). A learned map for places and concepts in the human medial temporal lobe. (upenn.edu)
Left temporal lobe1
- We shed light on this question through a case study of an individual (EG) born without a left temporal lobe. (biorxiv.org)
Chronic temporal lobe epi1
- Sparks FT, Liao Z, Li W, Grosmark A, Soltesz I , Losonczy A. Hippocampal adult-born granule cells drive network activity in a mouse model of chronic temporal lobe epilepsy. (neurotree.org)
Atrophy4
- Thalamic atrophy and cognition in unilateral temporal lobe epilepsy. (utah.edu)
- Longitudinal and cross-sectional analysis of atrophy in pharmacoresistant temporal lobe epilepsy. (mpg.de)
- Mapping limbic network organization in temporal lobe epilepsy using morphometric correlations: insights on the relation between mesiotemporal connectivity and cortical atrophy. (mpg.de)
- This article is aimed to describe the case of a 23 years old female with left hemifacial atrophy and dermatologic, dental, and neurologic compromise, associated with refractory temporal lobe epilepsy evidenced in neuroimaging and electrodiagnostic testings. (j-epilepsy.org)
20181
- Epilepsia 2018 8 59 (9): e152-e156. (cdc.gov)
Medically3
- The "Natural" History of Medically Treated Temporal Lobe Epilepsy: What Can an Evidence-Based Approach Tell Us? (hindawi.com)
- We systematically reviewed the literature to describe the "natural" history of medically treated temporal lobe epilepsy (TLE). (hindawi.com)
- Temporal lobe epilepsy (TLE) is the most frequent medically refractory epilepsy syndrome seen in epilepsy outpatient clinics. (hindawi.com)
20211
- Epilepsia 2021, 62 (3), 729-741. (ncl.ac.uk)
Cortical6
- Medial prefrontal and anterior cingulate cortical thickness predicts shared individual differences in self-generated thought and temporal discounting. (mpg.de)
- Graph-theoretical analysis reveals disrupted small-world organization of cortical thickness correlation networks in temporal lobe epilepsy. (mpg.de)
- Increased temporo-limbic cortical folding complexity in temporal lobe epilepsy. (mpg.de)
- Cortical thickness analysis in temporal lobe epilepsy: reproducibility and relation to outcome. (mpg.de)
- La displasia cortical focal en el lóbulo temporal se asocia a EPILEPSIA DEL LÓBULO TEMPORAL. (bvsalud.org)
- Focal cortical dysplasia in the temporal lobe is associated with TEMPORAL LOBE EPILEPSY. (bvsalud.org)
Pediatric2
- Default mode network deactivation in pediatric temporal lobe epilepsy: Relationship to a working memory task and executive function tests. (ucdavis.edu)
- Oyegbile TO, VanMeter JW, Motamedi G, Zecavati N, Santos C, Chun CLE, Gaillard WD, Hermann B. Executive dysfunction is associated with an altered executive control network in pediatric temporal lobe epilepsy. (ucdavis.edu)
Cerebral Cortex1
- Abnormal, non-neoplastic cell proliferation of the CEREBRAL CORTEX confined to an area in any lobe. (bvsalud.org)
Psychiatric2
- 71 Psychiatric disorders are more common among those with epilepsy, and the highest prevalence occurs among those with temporal lobe epilepsy. (wikipedia.org)
- Quality of life and comorbid medical and psychiatric conditions in temporal lobe epilepsy. (utah.edu)
Genetic1
- Infections, brain injury, a tumor, genetic mutations , or changes in brain structure all can cause temporal lobe epilepsy. (teenshealth.org)
Familial1
- Familial temporal lobe epilepsy: a common disorder identified in twins. (medscape.com)
Patients2
- In many cases, epilepsy surgery can lead to very good results for patients with temporal lobe epilepsy. (teenshealth.org)
- Basal temporal sulcal morphology in healthy controls and patients with temporal lobe epilepsy. (mpg.de)
Surgical1
- Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. (medscape.com)
20231
- Epilepsia;64(10): 2827-2840, 2023 10. (bvsalud.org)
Radiosurgery1
- The value of radiosurgery as a "lesion generator" was based on small and large animal studies that defined the critical dose, the volume, and the temporal evolution of the radiosurgical lesion. (surgicalneurologyint.com)
Cognition2
- Extrahippocampal integrity in temporal lobe epilepsy and cognition: thalamus and executive functioning. (utah.edu)
- However, another network implicated in high-level cognition- the domain-general multiple demand, MD, network-is robustly present in both right and left frontal lobes, suggesting that EG's left frontal cortex is capable of supporting non-linguistic cognitive functions. (biorxiv.org)
Onset1
- Temporal lobe epilepsy is the most common type of focal onset epilepsy among adults. (wikipedia.org)
Pathology1
- Mapping thalamocortical network pathology in temporal lobe epilepsy. (mpg.de)
Amygdala1
- Synergism of perampanel and zonisamide in the rat amygdala kindling model of temporal lobe epilepsy. (uni-muenchen.de)
Neuroinflammation1
- Identification of brain regions predicting epileptogenesis by serial [F-18]GE-180 positron emission tomography imaging of neuroinflammation in a rat model of temporal lobe epilepsy. (uni-muenchen.de)
Distinguish1
- Memory test distinguish between patient with focal temporal and extratemporal lobe epilepsy. (bvsalud.org)
Brain5
- Here, we aimed to study brain dystrophin distribution and expression in both, human and experimental temporal lobe epilepsy (TLE). (frontiersin.org)
- The temporal lobes are on the sides of the brain, behind the temples. (teenshealth.org)
- Imaging structural and functional brain networks in temporal lobe epilepsy. (mpg.de)
- High-level language processing is supported by a left-lateralized fronto-temporal brain network. (biorxiv.org)
- In the adult human brain, language processing recruits a fronto-temporal network (e.g. (biorxiv.org)
Molecular2
- Given these observations, insight into the molecular mechanism responsible for the subclass-specific vulnerability of interneurons to SE-induced cell death may provide a deeper understanding of temporal lobe epileptogenesis. (jneurosci.org)
- In 2005, based upon research involving several large French-Canadian families that presented with temporal lobe epilepsy, an expanded conceptualization of the molecular genetics of the autosomal recessive form NA was attained. (medscape.com)
Development2
- Excitotoxic cell death is one of the precipitating events in the development of temporal lobe epilepsy. (jneurosci.org)
- Given that frontal cortex in general exhibits protracted development, frontal language areas presumably emerge later and/or mature more slowly than temporal language areas. (biorxiv.org)
Publication1
- We have the opportunity today to talk about a recent publication [ 1 ] of yours in Epilepsia about the responsive neurostimulator (RNS). (medscape.com)
Volume1
- MRI volume loss of subcortical structures in unilateral temporal lobe epilepsy. (utah.edu)