• The biofilm bacteria can share nutrients and are sheltered from harmful factors in the environment, such as desiccation, antibiotics, and a host body's immune system. (wikipedia.org)
  • They can be found very early in Earth's fossil records (about 3.25 billion years ago) as both Archaea and Bacteria, and commonly protect prokaryotic cells by providing them with homeostasis, encouraging the development of complex interactions between the cells in the biofilm. (wikipedia.org)
  • The first colonist bacteria of a biofilm may adhere to the surface initially by the weak van der Waals forces and hydrophobic effects. (wikipedia.org)
  • Hydrophobicity can also affect the ability of bacteria to form biofilms. (wikipedia.org)
  • Biofilm is a complex matrix consisting of extracellular polysaccharides, DNA, and proteins that protect bacteria from a variety of physical, chemical, and biological stresses allowing them to survive in hostile environments. (intechopen.com)
  • Bacteria can be found in planktonic form or in specific conditions, as sessile aggregates on both biotic and abiotic surfaces originating complex structures known as biofilm. (intechopen.com)
  • The biofilm matrix consists of polysaccharides, proteins, and DNA and constitutes a stubborn source that protects bacteria from a variety of physical, chemical, and biological stresses. (intechopen.com)
  • Six diatom species displayed specific anti-inflammatory, anticancer (blocking human melanoma cell proliferation), and anti-biofilm (against the bacteria Staphylococcus epidermidis ) activities whereas, none of the other microalgae were bioactive against the conditions tested for. (frontiersin.org)
  • Bacteria living in colonies form a protective shield known as a biofilm. (traceminerals.com)
  • 8 Later research found it could block biofilm formation of a number of bacteria, including the dental pathogen Enterococcusfaecalis . (traceminerals.com)
  • Resident skin bacteria, such as Staphylococcus epidermidis and Staphylococcus aureus, are thought to play a role in the pathogenesis of miliaria, possibly through formation of biofilms. (medscape.com)
  • To help prevent biofilms from forming on the surfaces of these devices, researchers at Harvard's School of Engineering and Applied Sciences and Wyss Institute for Biologically Inspired Engineering have developed a new coating technology that sheds any bacteria forming on it. (medgadget.com)
  • Bacteria accumulates into adhesive colonies called biofilms , which help them survive and protect them from outside threats. (zmescience.com)
  • To test the effectiveness of the super slippery surface, the study's lead author Noah MacCallum, an exchange undergraduate student at SEAS, exposed treated and untreated medical tubing to Pseudomonas aeruginosa , Escherichia coli , and Staphylococcus epidermidis , which are common pathogenic bacteria that form biofilms and are the most common culprits in blood and urinary infections. (zmescience.com)
  • With widespread antibiotic resistance cropping up in many strains of infection-causing bacteria, developing out-of-the-box strategies to protect patients from bacterial biofilms has become a critical focus area for clinical researchers," said Wyss Institute Founding Director Donald Ingber , who is also the Judah Folkman Professor of Vascular Biology at Harvard Medical School and Boston Children's Hospital and Professor of Bioengineering at Harvard SEAS. (zmescience.com)
  • 1,2 The unique structure of biofilms protects bacteria from the surrounding environment, conferring a capacity for persistence against phagocytosis, oxidative stresses, nutrient/oxygen restriction, metabolic waste accumulation, interspecies competition, and conventional antimicrobial agents. (rsc.org)
  • 2,9-11 A comprehensive understanding of the interactions between bacteria and materials with different surface topographies may pave the way for more effective strategies to control biofilm growth. (rsc.org)
  • Bacteria survive in various environments by forming biofilms. (biomedcentral.com)
  • In this study, we evaluated the ability of two types of biosurfactants (rhamnolipids and surfactin) to inhibit growth and biofilm formation ability of oral pathogenic bacteria such as Aggregatibacter actinomycetemcomitans , Streptococcus mutans , and Streptococcus sanguinis . (biomedcentral.com)
  • Rhamnolipids inhibited the growth and biofilm formation ability of all examined oral bacteria. (biomedcentral.com)
  • Streptococcus mutans , a representative bacteria of tooth decay [ 10 ], forms plaques (biofilm) on tooth surfaces and produces lactate from sugars such as sucrose, which demineralizes teeth and causes dental caries. (biomedcentral.com)
  • Therefore, removal of biofilms formed by periodontopathogenic bacteria prevents a variety of diseases. (biomedcentral.com)
  • Anti-bacterial agents and disinfectants are effective against planktonic bacteria (bacteria suspended in liquid), however, they are not effective against biofilm-forming bacteria due to the difficulty of chemicals penetrating the biofilm. (biomedcentral.com)
  • Therefore, biofilm matrix gives the additional resistance power to bacteria which makes them to not only tolerate harsh conditions but also resistant to antibiotics which lead to the emergence of bad bugs infections like multi drug resistant, extensively drug resistant and totally drug resistant bacteria. (biomedcentral.com)
  • In her paper, she states that biofilms are a protective layer created by microbes including bacteria and mold. (nodawaynews.com)
  • The most important bacteria of the conjunctival microbiota are Staphylococcus epidermidis, diphteroid rods, Corynebacterium spp. (dergisi.org)
  • The result of our study suggests that there are no significant changes in bacterial ratios before and after lens use, but bacteria such as S. epidermidis can predispose to infections by using slime production and contact lens factor. (dergisi.org)
  • Any drug impairing crucial processes for bacterial life will inevitably lead to the development of drug-resistant strains, whereas the inhibition of biofilm formation might prevent the onset of bacterial resistance. (intechopen.com)
  • In this section, we will focus on proteins involved in biofilm formation as useful targets for the development of new drugs that can effectively and specifically impair biofilm formation with slight effects on cell survival, thus avoiding the generation of drug-resistant strains. (intechopen.com)
  • There are between 10 and 24 strains of S. epidermidis on healthy adult skin. (dermnetnz.org)
  • S. epidermidis strains that produce PAS-positive extracellular polysaccharide substances (EPS) [4]. (dermnetnz.org)
  • Miliaria is not associated with non-EPS producing strains of S. epidermidis or another coagulase-negative staphylococcus, such as S. haemolyticus and S. hominis . (dermnetnz.org)
  • Of note, up to 62% of S. epidermidis strains on the forehead and back produce EPS [4,5]. (dermnetnz.org)
  • In an experimental setting, only the strains of S epidermidis that produce EPS can induce miliaria. (medscape.com)
  • In-vitro biofilm formation of staphylococcal strains on CaP bone grafts: CaP bone grafts will be incubated in pooled human serum. (forschung3r.ch)
  • In-vivo biofilm formation of staphylococcal strains on CaP bone grafts: Biofilm will be formed in tissue cages in the back of guinea pigs. (forschung3r.ch)
  • The strains were allowed to form biofilm in vitro. (jmb.or.kr)
  • The objective of the present study was to evaluate the antibacterial, antibiofilm, and synergistic effect of triterpene 3ß,6ß,16ß-trihydroxyilup-20(29)-ene (CLF1) against Staphylococcus aureus and Staphylococcus epidermidis strains. (bvsalud.org)
  • The synergistic effect with ampicillin was observed only for S. epidermidis strains. (bvsalud.org)
  • Moreover, CLF1 significantly inhibited the biofilm formation and disrupted preformed biofilm of the all strains. (bvsalud.org)
  • Before lens usage, slime positive S. epidermidis strains were found as 45-50% but after lens usage it was 59% in hydrogel contact lens users and 70.2% in silicone hydrogel contact lens users. (dergisi.org)
  • For the investigation of slime production, 82 (50.9%) of 161 S. epidermidis strains were found positive by using Congo red agar, 61 (37.8%) by standard tube method and 91 (56.5%) by molecular methods. (dergisi.org)
  • Analysis of a flow culture of Pseudomonas aeruginosa through untreated PDMS and iPDMS tubing shows at least an order of magnitude reduction of biofilm formation on iPDMS, and almost complete absence of biofilm on iPDMS after a gentle water rinse. (medgadget.com)
  • The carboxybetaine precursors undergo rapid, self-catalysed hydrolysis at the water/material interface and provide critical anti-fouling properties that lead to undetectable bacterial attachment and zero biofilm formation after six months of constant exposure to Pseudomonas aeruginosa and Staphylococcus epidermidis under the static condition in a nutrient-rich medium. (european-coatings.com)
  • Here, we investigated bacterial attachment, cell alignment and biofilm formation of Pseudomonas aeruginosa on periodic nano-pillar surfaces with different pillar spacing. (rsc.org)
  • 4,5 For example, Pseudomonas aeruginosa , an organism well-known for its capacity to form biofilms, is an opportunistic pathogen and is one of the top three causes of opportunistic human infections, 6 causing nosocomial infections in catheter lines, or chronically infecting the lungs of cystic fibrosis patients. (rsc.org)
  • To this end, the anti-biofilm effect of cell-free supernatant of Pseudomonas sp. (unisa.it)
  • Among these isolates 44.29% were assessed as strong biofilm forming. (rjptonline.org)
  • Six gram-positive isolates (54.55%) and 31 isolates (48.44%) of gram-negative bacilli were strong biofilm forming. (rjptonline.org)
  • Resistance to antibiotics was higher among biofilm forming isolates than non-biofilm forming ones. (rjptonline.org)
  • Formation and properties of in vitro biofilms of ica-negative Staphylococcus epidermidis clinical isolates. (alliedmortgage.ca)
  • Her research was on PAC Power: Analysis of the effect of cranberry proanthocyanidin (PAC) on biofilm density of clinical and commensal Staphylococcus epidermidis (S. epidermidis) isolates, a two-year study. (nodawaynews.com)
  • Whole genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteremia is caused by a limited number of closely related sequence types. (cdc.gov)
  • As a demonstration, we show the preparation of silicone-coated polyurethane catheters and significant reduction of Escherichia coli and Staphylococcus epidermidis biofilm formation on the catheter surface. (medgadget.com)
  • Otherwise, secondary ADF is an uncommon (0.3% - 2%) and life-threatening long-term complication of aortic reconstructive surgery, with only hypothetic and speculative pathogenesis (mechanical erosion, lack of interposed retroperitoneal tissue, excessive pulsation of redundantly placed grafts, septic procedures by Staphylococcus epidermidis ¡°biofilm¡± infection, inadequate prosthetic materials). (sciencedaily.com)
  • TAE6080, a possibly new bacterium isolated in 1994 during water column samplings near the French Antarctic station Dumont d'Urville, is capable of inhibiting the formation of Staphylococcus epidermidis biofilm, known to be an important opportunistic pathogen in infections associated to medical devices. (unisa.it)
  • My research was based on Staphylococcus epidermidis biofilm formation. (nature.com)
  • Bacterial biofilms play an important role in UTIs, responsible for persistent infections leading to recurrences and relapses. (mdpi.com)
  • Now, with the increasing use of implanted medical equipment, they have become leading pathogens for nosocomial infections owing to their ability to form biofilms on foreign material [1,2]. (dermnetnz.org)
  • Collectively, S. epidermidis and S. haemolyticus account for the majority of foreign body and premature neonatal infections due to coagulase-negative staphylococci [1]. (dermnetnz.org)
  • Bacterial biofilms are a cause of countless challenging infections originating from implanted medical devices, urinary and intravenous catheters, and other clinical tools that interface with the human body. (medgadget.com)
  • Harvard researchers have demonstrated a powerful, long-lasting repellent surface technology that can be used with medical materials to prevent infections caused by biofilms. (zmescience.com)
  • 3 Bacterial biofilms can cause persistent human infections and can foul the surface of medical devices. (rsc.org)
  • 3,6 Biofilm formation by P. aeruginosa is responsible for antimicrobial tolerance and causes major problems for treatment of infections. (rsc.org)
  • 3,8 Therefore, it is important to develop biomaterials that can control biofilm growth thereby reduce infections. (rsc.org)
  • These implant-associated infections are typically caused by micro-organisms that grow in biofilms (1). (forschung3r.ch)
  • The planned experiment will compare the data of our in-vitro biofilm experiments on bone grafts with data from biofilms produced in-vivo in an established animal model for foreign body infections (5-7). (forschung3r.ch)
  • This study aimed to investigate the etiologic agents of diabetic foot infections, their antimicrobial resistance and biofilm formation ability. (rjptonline.org)
  • There are many approaches being used to control infections by suppressing its formation but CRISPR-CAS (gene editing technique) and photo dynamic therapy (PDT) are proposed to be used as therapeutic approaches to subside bacterial biofim infections, especially caused by deadly drug resistant bad bugs. (biomedcentral.com)
  • Her paper also states that S. epidermidis is the leading cause of biofilm-associated infections related to medical devices such as catheters, shunts, artificial valves and orthopedic devices. (nodawaynews.com)
  • Especially biofilm formation of S. epidermidis is very important for contact lens related infections. (dergisi.org)
  • In this study, 21 diatoms, 7 dinoflagellates, and 4 flagellate species were grown in three different culturing conditions and the corresponding extracts were tested for possible antioxidant, anti-inflammatory, anticancer, anti-diabetes, antibacterial, and anti-biofilm activities. (frontiersin.org)
  • The material demonstrates both critical anti-biofilm properties and tunable mechanical properties. (european-coatings.com)
  • According to the researchers, this zwitterionic polyurethane is the first material to demonstrate both critical anti-biofilm properties and tunable mechanical properties. (european-coatings.com)
  • Liquid-infused polymers could be used to prevent biofilms from ever taking hold, potentially reducing rates of infection and therefore reducing dependence on antibiotic use. (zmescience.com)
  • Researchers have presented a noveal approach to prevent biofilms. (european-coatings.com)
  • Mechanical removal of biofilm on titanium discs: An in vitro study. (gu.se)
  • Effectiveness of topical adjuvants in reducing biofilm formation on orthopedic implants: an in vitro analysis. (harvard.edu)
  • We recently established an in-vitro setting to analyse biofilm formation on bone grafts and bone graft substitutes (3), and showed in-vitro the importance to monitor (i) material properties (3), and (ii) incubation conditions (4) when investigating biofilm formation on bone grafts. (forschung3r.ch)
  • Importantly, it remains unclear whether these in-vitro data are meaningful for in-vivo biofilm formation. (forschung3r.ch)
  • The aim of this project is (i) to compare in-vitro and in-vivo biofilm formation on the surface of calcium phosphate (CaP, Fig. 1) bone grafts, and (ii) to establish an in-vitro setting for biofilm formation to reduce the number of animals needed in preclincial trials for testing infect susceptibility of bone grafts in general. (forschung3r.ch)
  • In-vitro biofim formation on bone grafts will be compared with in-vivo biofilm formation. (forschung3r.ch)
  • The results should form a basis to develop a valid in-vitro screening test for biofilm formation on the surface of medical devices, helping to reduce the number of animals needed for definitive pre-clinical in-vivo tests. (forschung3r.ch)
  • Capsicumicine, a New Bioinspired Peptide from Red Peppers Prevents Staphylococcal Biofilm In Vitro and In Vivo via a Matrix Anti-Assembly Mechanism of Action. (univ-rennes.fr)
  • Furthermore, genome sequencing, assembly and mining revealed a plethora of putative biosynthetic gene clusters that might be involved in biofilm disruption. (unisa.it)
  • Silver-doped biopolymer films also totally impair the formation of bacterial biofilms, with undetectable biofilm cells in several cases (∼7.5 log or 99.99999% inhibition). (researchgate.net)
  • The experimental and genomic data presented here open the venue to further investigations on the molecular basis underlying biofilm inhibition. (unisa.it)
  • Metabolic activity of the bacterial biofilm communities have altered as compared to the planktonic one such as increased rates of EPS production, activation or inhibition of particular genes associated with biofilm formation and decreased growth rate [ 39 ]. (biomedcentral.com)
  • Biofilm prevention, inhibition and controlling process (antibiofilm) using natural or synthetic peptides derived from 2S-sulfur-rich seed storage protein 2-like protein or their peptidomimetic (synthetic) derivatives. (univ-rennes.fr)
  • Biofilm formation requires three different stages: cell attachment to a solid substrate, adhesion, and growth. (intechopen.com)
  • We report here that myricetin, but not its glycosylated form, can remarkably decrease the production of several S. aureus virulence factors, including adhesion, biofilm formation, hemolysis and staphyloxanthin production, without interfering with growth. (nature.com)
  • Planar and tubular geometry silicone substrates can be infused with nontoxic silicone oil to create a stable, extremely slippery interface that exhibits exceptionally low bacterial adhesion and prevents biofilm formation. (medgadget.com)
  • The experiment confirmed what scientists believed - that the surface greatly reduces biofilm adhesion and largely (though not totally) eliminated biofilm formation. (zmescience.com)
  • Red pepper peptide coatings control Staphylococcus epidermidis adhesion and biofilm formation. (univ-rennes.fr)
  • The aim of this study was to investigate the antibacterial and antibiofilm properties of low viscosity chitosan on S. epidermidis growth and biofilm formation. (niom.no)
  • However, only collagen scaffolds loaded with 100 μg/ml of Cefaclor showed adequate antibacterial properties against both E-coli and Staphylococcus epidermidis . (phys.org)
  • Superinfection of the showed only one or two lesions and, that except for itching lesions had led to pustule formation, suppuration, and and local pain, no clinical pathology was observed. (cdc.gov)
  • En mayo de 2007 obtuve el Certificate of Training in Molecular Biological Techniques en el Department of Molecular Biology y desde Junio de 2008 a Junio de 2009 completé el Certificate in Clinical Research en el Center for Translational Science Activities en Mayo Clinic College of Medicine, Rochester Minnesota. (unav.edu)
  • Un 40% de esos trabajos han sido publicados en revistas del primer cuartil entre las que destacan New England Journal of Medicine, Lancet, Lancet Infectious Diseases, Clinical Infectious Diseases, Clinical Microbiology Reviews, Antimicrobial Agents and Chemotherapy, Journal Clinical Microbiology, Journal Antimicrobial Chemotherapy, Mayo Clinic Proceedings y Malaria Journal. (unav.edu)
  • Biofilms may form on living (biotic) or non-living (abiotic) surfaces and can be prevalent in natural, industrial, and hospital settings. (wikipedia.org)
  • Bacterial cells can colonize surfaces and form biofilms that consist of microbial cells embedded in extracellular polymeric substances (EPS). (rsc.org)
  • Cranberry extracts containing PAC have been shown to affect biofilm production emitted by S.epidermidis by interfering with bacteria's ability to adhere to surfaces. (nodawaynews.com)
  • The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides, proteins, lipids and DNA. (wikipedia.org)
  • The microbial cells growing in a biofilm are physiologically distinct from planktonic cells of the same organism, which, by contrast, are single cells that may float or swim in a liquid medium. (wikipedia.org)
  • Biofilms are an ensemble of microbial cells irreversibly associated with a surface and enclosed in an essentially self-produced matrix. (intechopen.com)
  • Such bacterial biofilms tend to form on medical equipment, including surgery equipment heart valves, urinary catheters, intravenous catheters, and implants. (zmescience.com)
  • The microbial diversity of biofilm communities of central venous catheters was not satisfactory examined. (muni.cz)
  • Microbes form a biofilm in response to a number of different factors, which may include cellular recognition of specific or non-specific attachment sites on a surface, nutritional cues, or in some cases, by exposure of planktonic cells to sub-inhibitory concentrations of antibiotics. (wikipedia.org)
  • Microbial forms living in biofilms are morphologically and functionally distinct from those of free-floating (planktonic) forms of the same species. (jmb.or.kr)
  • Staphylococcus epidermidis Contributes to Healthy Maturation of the Nasal Microbiome by Stimulating Antimicrobial Peptide Production. (harvard.edu)
  • The biofilms susceptibility was assessed by enumeration of colony-forming units (CFUs) and quantification of total biomass by crystal violet staining. (bvsalud.org)
  • After the irrigation protocol, the biofilm susceptibility to disinfecting solutions (n=10) was determined by colony-forming unit (CFU) quantification. (bvsalud.org)
  • Publishing their results today in the journal Biomedical Materials , the team from the National University of Ireland Galway show that stabilised collagen scaffolds loaded with a particular antibiotic were able to prevent both Escherichia coli and Staphylococcus epidermidis from forming. (phys.org)
  • Subpopulations of cells within the biofilm differentiate to perform various activities for motility, matrix production, and sporulation, supporting the overall success of the biofilm. (wikipedia.org)
  • Biofilm spreading by the adhesin-dependent gliding motility of Flavobacterium johnsoniae. (chikarasato.com)
  • For example, if Staphylococcus aureus cells are living in a biofilm, they are often extremely difficult to kill with antibiotics. (nature.com)
  • The biofilm is resistant to antibiotics, disinfectants and the host's immune system. (nodawaynews.com)
  • She wrote "microbes can actually become a thousand times more resistant to antibiotics when protected by a biofilm. (nodawaynews.com)
  • Coagulase-negative staphylococci are gram-positive, aerobic organisms distinguished from the closely related Staphylococcus aureus by the group's inability to form coagulase, an enzyme that promotes thrombus formation via the conversion of fibrinogen into fibrin [2]. (dermnetnz.org)
  • Small molecules produced by commensal Staphylococcus epidermidis disrupt formation of biofilms by Staphylococcus aureus . (ku.edu)
  • Then samples will be infected by inoculation with 1 x 105 colony-forming units (cfu) of either S. aureus ATCC 29213 (MSSA), S. aureus ATCC 43300 (MRSA) or S. epidermidis RP62A ATCC 35984 (MSSE). (forschung3r.ch)
  • These tissue cages, which have been prefilled with CaP grafts, will be infected by inoculation with 1 x 105 cfu of either S. aureus ATCC 29213 (MSSA), S. aureus ATCC 43300 (MRSA) or S. epidermidis RP62A ATCC 35984 (MSSE). (forschung3r.ch)
  • Scanning electron microscopy (SEM) images showed changes in the cell morphology and structure of S. aureus ATCC 700698 biofilms (a methicillin-resistant S. aureus strain). (bvsalud.org)
  • The results clearly demonstrated that rhamnolipids inhibit biofilm formation after the initiation process, however, they do not affect attachment or maturation. (biomedcentral.com)
  • iii) colony formation and biofilm maturation. (biomedcentral.com)
  • The aim of this project is to study of species composition of biofilm communities by cultivation and molecular methods and assessment of the differences in poly-microbial communities in relation to therapy failure, length of insertion of catheter, its type and other factors including predominating microbial species. (muni.cz)
  • A biofilm comprises any syntrophic consortium of microorganisms in which cells stick to each other and often also to a surface. (wikipedia.org)
  • Biofilms can attach to a surface such as a tooth or rock, and may include a single species or a diverse group of microorganisms. (wikipedia.org)
  • A biofilm usually begins to form when a free-swimming bacterium attaches to a surface. (wikipedia.org)
  • The formation of a biofilm begins with the attachment of free-floating microorganisms to a surface. (wikipedia.org)
  • This blockage results in the leakage of sweat en route to the skin surface, either in the dermis or epidermis, with relative anhidrosis. (medscape.com)
  • Surface topography designed to achieve spatial segregation has shown promise in delaying bacterial attachment and biofilm growth. (rsc.org)
  • In particular, surface modifications that physically create rational surface topographies have attracted attention in recent years, and have shown to inhibit bacterial attachment and biofilm growth without the use of antimicrobials. (rsc.org)
  • Biofilms are three-dimensional structures consisting of various microbial populations attached to a surface by extracellular polymeric substances (EPS) produced by these microorganisms [ 1 ]. (biomedcentral.com)
  • Glycopeptidolipids are indispensable for initial surface attachment during biofilm formation in Mycobacterium smegmatis [ 111 ]. (biomedcentral.com)
  • Growth pattern of Mycobacterium species are different such as M. chelonae and M. fortuitum form biofilm as vertical and entire surface growth, respectively [ 93 ]. (biomedcentral.com)
  • 2. Filamentous Extracellular Network and Cell-to-Cell Connections at the Biofilm Surface. (chikarasato.com)
  • To corroborate these results, biofilms were observed by scanning electron microscopy (SEM) and confocal microscopy. (biomedcentral.com)
  • Four teeth were analyzed by scanning electron microscopy (SEM) to confirm the presence of biofilm. (bvsalud.org)
  • Treatment of established biofilm with NEBB resulted in biofilm-disruption, involving significant reductions in biofilm mass and metabolic activity for Candida and both Staphylococcus species. (jmb.or.kr)
  • S.epidermidis was the most frequently isolated species in conjunctival microbiota before and after lens usage. (dergisi.org)
  • Streptococcus sanguinis is another plaque-forming strain that has been reported to cause infective endocarditis by forming biofilms on the endocardium and heart valves [ 11 ]. (biomedcentral.com)
  • This group comprises predominantly of S. epidermidis, S. haemolyticus, S. capitis, S. hominis, S. simulans and S. warneri [1]. (dermnetnz.org)
  • A cell that switches to the biofilm mode of growth undergoes a phenotypic shift in behavior in which large suites of genes are differentially regulated. (wikipedia.org)
  • Rhamnolipids inhibit oral bacterial growth and biofilm formation by A. actinomycetemcomitans Y4, and may serve as novel oral drug against localized invasive periodontitis. (biomedcentral.com)
  • Therefore, inhibiting the growth of oral pathogens, as well as effectively preventing biofilm formation contribute to reducing these risks. (biomedcentral.com)
  • Thus, there is a requirement for the development of a simpler and more effective oral care capable of inhibiting oral bacterial growth and biofilm formation. (biomedcentral.com)
  • For P. aeruginosa , low doses of NEBB significantly reduced biofilm mass and metabolic activity while higher doses of NEBB increased biofilm mass and metabolic activity. (jmb.or.kr)
  • In 90.16% of MDR pathogens, biofilm formation was positive. (rjptonline.org)
  • Due to the great involvement of diabetic foot ulcer in non-traumatic foot amputations, it is of significance to identify the causative pathogens of these ulcers, their antibiogram and biofilm formation in order to select the proper therapy. (rjptonline.org)
  • The post-treatment biofilm mass was evaluated by crystal-violet staining, and metabolic activity was measured using the MTT assay. (jmb.or.kr)
  • The observations were largely in concordance with the biofilm assay results. (biomedcentral.com)
  • Average biofilm mass and metabolic activity for NEBB-treated biofilms were compared to the average of untreated control cultures. (jmb.or.kr)
  • For B. burgdorferi , we observed reduced biofilm mass, but the remaining residual biofilm showed a mild increase in metabolic activity, suggesting a shift from metabolically quiescent, treatment-resistant persister forms of B. burgdorferi to a more active form, potentially more recognizable by the host immune system. (jmb.or.kr)
  • Miliaria is thought to be caused by blockage of the sweat ducts, which results in the leakage of eccrine sweat into the epidermis or dermis. (medscape.com)
  • In miliaria rubra, obstruction occurs deeper within the epidermis and results in extremely pruritic erythematous papules. (medscape.com)
  • In contrast, in miliaria rubra, the leakage of sweat into the subcorneal layers produces spongiotic vesicles and a chronic periductal inflammatory cell infiltrate in the papillary dermis and lower epidermis. (medscape.com)
  • For this purpose, we aimed to examine the changes in the presence of biofilm-forming S. epidermidis and other coagulase-negative staphylococci in conjunctival swabs taken before and after lens usage in 140 patients (90 hydrogel, 50 silicone hydrogel) who were prepared to wear lenses. (dergisi.org)
  • Although physical methods are fundamental for removing oral biofilms, there is a wide variation in its efficiency due to individual differences. (biomedcentral.com)
  • Biofilms can form on the teeth of most animals as dental plaque, where they may cause tooth decay and gum disease. (wikipedia.org)
  • Microbial biofilms form on liquid/solid interfaces in nature, such as rocks and clay particles and decaying plant materials. (jmb.or.kr)
  • Aggregatibacter actinomycetemcomitans has been strongly associated with localized aggressive periodontitis via its ability to form biofilms in the subgingival cavity [ 12 ]. (biomedcentral.com)
  • Biofilm cultures were treated with NEBB containing enzymes targeted at lipids, proteins, and sugars, also containing the mucolytic compound N-acetyl cysteine, along with antimicrobial extracts from cranberry, berberine, rosemary, and peppermint. (jmb.or.kr)
  • Pseudonajide is a short peptide antibiotic derived from snake venom that acts at low concentration interfering with cell wall and inhibiting biofilm. (univ-rennes.fr)
  • The S. epidermidis group of coagulase-negative staphylococci are of particular importance. (dermnetnz.org)
  • Biofilm production was correlated with multidrug resistance. (rjptonline.org)
  • Techniques to inhibit biofilm formation are essential and have wide applications. (biomedcentral.com)