AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesInformation Science
TeratocarcinomaTeratomaEmbryonal Carcinoma Stem CellsTretinoinCell DifferentiationTumor Cells, CulturedBucladesineCell LineNeoplasms, ExperimentalTesticular NeoplasmsEndodermAntigens, CD15Hybrid CellsBeta-GlobulinsGrowth Differentiation Factor 3Molecular Sequence DataTranscription, GeneticBase SequenceBlastocystUridine Diphosphate N-AcetylgalactosamineRNA, MessengerHSP47 Heat-Shock ProteinsReceptors, Retinoic AcidNeoplastic Stem CellsEmbryo, MammalianCarcinoma, EmbryonalClone CellsRNA, NeoplasmCell AggregationGlucose-6-Phosphate IsomeraseNucleic Acid HybridizationCloning, MolecularNeoplasm TransplantationGenesButyric AcidDNAGene Expression RegulationTheophyllineAntigens, NeoplasmDNA, NeoplasmAmino Acid SequenceRetroviridaeTransfectionMice, Inbred StrainsPromoter Regions, Genetic
TDGF1CriptoFamilyCellGrowth factorDifferentiationProteinInducesReceptorHuman
TDGF11
  • Teratocarcinoma-derived growth factor 1 is a protein that in humans is encoded by the TDGF1 gene. (wikipedia.org)
Cripto2
  • Targeting the Cripto-1/TAK-1/NF-kappaB/Survivin pathway may be an effective approach to combat apoptosis resistance in cancer. (cusabio.com)
  • Human Cripto-1, also known as teratocarcinoma-derived growth factor-1 (TDGF-1), is a member of the Epidermal growth factor-cripto FRL1 cryptic (EGF-CFC) family (Cripto in humans, FRL1 in Xenopus, and Cryptic in mice), which is indispensable for early embryonic development[ 4 ]. (biomedcentral.com)
Family1
  • CFC1 inhibited Activin A-induced NB cell differentiation and Smad2 phosphorylation in NB cell lines, indicating its involvement in tumorigenesis related to EGF-CFC co-receptor family molecule pathways. (oncotarget.com)
Cell1
  • The term "oncotarget" encompasses all molecules, pathways, cellular functions, cell types, and even tissues that can be viewed as targets relevant to cancer as well as other diseases. (oncotarget.com)
Growth factor3
  • 8. Hinokitiol induces cell death and inhibits epidermal growth factor-induced cell migration and signaling pathways in human cervical adenocarcinoma. (nih.gov)
  • Cripto is an EGF-CFC or epidermal growth factor-CFC, which is encoded by the Cryptic family 1 gene. (assaysolution.com)
  • This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. (nih.gov)
Differentiation2
Protein2
  • Cryptic family protein 1B acts as a receptor for the TGF beta signaling pathway. (assaysolution.com)
  • It has been associated with the translation of an extracellular protein for this pathway. (assaysolution.com)
Induces1
  • 14. Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells. (nih.gov)
Receptor1
  • Activation and overexpression of programmed death 1 (PD-1) receptor is considered to one of the pathways to inhibit T-cell response in human leprosy. (bvsalud.org)
Human1
  • In humans developmental origin and pathways of thymic DCs were mainly studied in culture (18-20) or in immunodeficient mouse-human chimeras (21) using cord blood (CB) and fetal or newborn thymus for a progenitor source. (smartrailexpo-europe.com)