• CARL pioneered computational mapping of 'chaotic' heart rhythm disturbances (arrhythmias), targeting mechanistic drivers for atrial and ventricular fibrillation (AF, VF) using machine learning and computational models. (stanford.edu)
  • This study examined the utility of endocardial unipolar voltage mapping for detection of viable intramural-epicardial atrial myocardium. (bvsalud.org)
  • Perform echocardiography and/or MRI, primarily to exclude arrhythmogenic right ventricular cardiomyopathy, as well as to assess for other potential causes of arrhythmias. (medscape.com)
  • However, its potential utility in ventricular myocardium is unknown. (bvsalud.org)
  • At the Lab of Neuroimaging of Dr. Arthur Toga, PhD at UCLA, he developed optical mapping and image processing software to study somatosensory cortex (Research MD, 1995). (stanford.edu)
  • However, such an examination is necessary to exclude other potential cardiac causes of syncope or cardiac arrest in an otherwise healthy patient (eg, heart murmurs from hypertrophic cardiomyopathy or from a valvular or septal defect). (medscape.com)
  • Brugada syndrome is a disorder characterized by sudden death associated with one of several ECG patterns characterized by incomplete right bundle-branch block and ST-segment elevations in the anterior precordial leads. (medscape.com)
  • Three types of ST-segment elevation in Brugada syndrome, as shown in the precordial leads on ECG in the same patient at different times. (medscape.com)
  • The overall magnitude of the heart's electrical potential is then measured from twelve different angles ("leads") and is recorded over a period of time (usually ten seconds). (wikipedia.org)
  • action potentials]] of the individual cardiomyocytes are averaged. (ecgpedia.org)
  • Here we show that an increase in the late Na + current ( I NaL ) in aging cardiomyocytes prolongs the action potential (AP) and influences temporal kinetics of Ca 2+ cycling and contractility. (nature.com)
  • Unipolar signals gathered from mapping were used to calculate R:S within the left atrium of each animal. (utah.edu)
  • However, such an examination is necessary to exclude other potential cardiac causes of syncope or cardiac arrest in an otherwise healthy patient (eg, heart murmurs from hypertrophic cardiomyopathy or from a valvular or septal defect). (medscape.com)
  • If the cardiac muscle cells are electrically stimulated, they depolarize (the resting potential changes from negative to positive) and contract. (ecgpedia.org)
  • The electrical signal is written in blue and shows the action potential. (ecgpedia.org)
  • On the ECG, an action potential wave coming toward the electrode is shown as a positive (upwards) signal. (ecgpedia.org)
  • The upstroke of the action potential (AP) triggers Ca 2+ entry via L-type channels, which results in cytosolic Ca 2+ rise by the translocation of Ca 2+ from the sarcoplasmic reticulum (SR) to the cytoplasm, initiating cell contraction 7 . (nature.com)
  • This cohort study now analyzes the outcome of recurrent incisional hernia repair assessing potential risk factors based on data from the Herniamed registry. (bvsalud.org)
  • The FAO/WHO conclusions recognized the potential carcinogenic risk to the general public from consumption of starchy fried and baked foods containing acrylamide, and listed several research areas that should be investigated (Attachment 1). (nih.gov)
  • Left panel shows a type 1 ECG pattern with pronounced elevation of the J point (arrow), a coved-type ST segment, and an inverted T wave in V1 and V2. (medscape.com)
  • 1 The utilisation of modern 3D electroanatomical mapping and PVI-based ablation approaches in carefully selected patients with AF often offers therapeutic benefit. (aerjournal.com)
  • Three types of ST-segment elevation in Brugada syndrome, as shown in the precordial leads on ECG in the same patient at different times. (medscape.com)