OrganismsChemicals and Drugs
Ephedra sinicaEphedraEphedrineCaragana
HuangStapfEphedraceaeSpeciesShrubPseudoephedrineMedicinalGenusAlkaloidsAlkaloidChromium picolinateSeedsExtractToxicityBotanicalNevadensisIntermediaHerbDietary supplementsStemsStimulantPlantSupplementsRarely gives rise to side effectsCaffeine and ephedraAthletic performanceAsthmaFoundDiureticsStimulantsBotanicalsProductsCardiovascular diseaseChinaEfficacyMormonCombinationPotentially seriousLongWeight
Huang7
  • It is the primary source of the medicinal preparation ephedra, also known by its Chinese name ma huang. (wikipedia.org)
  • Ephedra sinica , also known as Ma Huang. (researchgate.net)
  • The Chinese botanical ephedra, or ma-huang, is sold as a dietary supplement in the United States. (nih.gov)
  • Dietary supplements that contain ephedra alkaloids (sometimes called ma huang) are widely promoted and used in the United States as a means of losing weight and increasing energy. (nih.gov)
  • FAMILY: Ephedraceae GENUS: Ephedra SPECIES: Sinica COMMON NAMES: Ask-for-trouble, Chinese Ephedra, Chinese Joint Fir, Chinesisches Meertraubel, Ma-huang, Ts'ao Ma-huang Ephedra sinica is a perennial horsetail plant which can grow up to 75 cm in height. (entheology.com)
  • The Ephedra (Ephedra Sinica or Ma Huang) Plant originated in China, and has been around for 1000's of years. (mysupplementstore.com)
  • The assign ephedra (ma huang) contains multiple chemical compounds, but the most pre-eminent is ephedrine. (estranky.cz)
Stapf2
  • 2. Inhibitory effect of ephedrannins A and B from roots of Ephedra sinica STAPF on melanogenesis. (nih.gov)
  • Dietary supplements containing herbal ephedra (chiefly Ephedra sinica Stapf. (nih.gov)
Ephedraceae4
  • [3] Ang Ephedra sinica sakop sa kahenera nga Ephedra , ug kabanay nga Ephedraceae . (wikipedia.org)
  • Premise of the Study Ephedra sinica (Ephedraceae) is a gymnosperm shrub with a wide distribution across Central and Eastern Asia. (bibbase.org)
  • article{jiao_development_2019, title = {Development of novel {EST}-{SSR} markers for {Ephedra} sinica ({Ephedraceae}) by transcriptome database mining}, volume = {7}, issn = {2168-0450}, url = {https://onlinelibrary.wiley.com/doi/abs/10.1002/aps3.1212}, doi = {10.1002/aps3.1212}, abstract = {Premise of the Study Ephedra sinica (Ephedraceae) is a gymnosperm shrub with a wide distribution across Central and Eastern Asia. (bibbase.org)
  • Ephedra is one of the largest genera of the Ephedraceae family, which is distributed in arid and semiarid regions of the world. (herbconer.com)
Species12
  • Cross-species amplifications were successfully conducted with two related Ephedra species for all 11 di- or trinucleotide simple sequence repeats. (bibbase.org)
  • Other Ephedra species with similar medicinal properties to ephedra grow throughout the northern hemisphere. (herbsandremedies.club)
  • In North America, related species were used to treat fevers and relieve kidney pain, while in India, Ephedra species were taken for asthma, hay fever, and rheumatism. (herbsandremedies.club)
  • North American ephedra species, such as E. nevadensis (known as Mormon tea), contain little or no ephedrine or other alkaloids [ 10 ]. (nih.gov)
  • Ephedra is best Grown in Rocky Deserts and Mountains, Beverages Made from Ephedra named as Yellow River, Mormom Tea, Whorehouse Tea, there are 10 Species in North America, and is Planted in Early Spring! (mysupplementstore.com)
  • about the possible interactions between herbal ephedra and biologically active compounds in the other plant species that are constituents of many dietary supplements. (nih.gov)
  • Ephedrine is a natural alkaloid obtained from ephedra species like ephedra sinica and ephedra officialis. (egpat.com)
  • It is usually found in other species such as Ephedra sinica. (herbconer.com)
  • Whereas other species contain ephedrine, ephedra nevadensis does not contain ephedrine. (herbconer.com)
  • Yoh should therefore be careful when othering for Mormon tea, lest you'd be served Ephedra tea, which are likely made from other Ephedra species, instead of Mormon tea. (herbconer.com)
  • Ephedra nevadensis (Nevada Ephedra) is an American species of Ephedra that can be found in dry areas of western North America. (ndgbotanicals.com)
  • This is why this species of Ephedra commonly gets the name Mormon Tea. (ndgbotanicals.com)
Shrub4
  • Ephedra is a low evergreen shrub with small scaly leaves. (nih.gov)
  • Ephedra pachyclada is an evergreen Shrub. (pfaf.org)
  • Ephedra is an evergreen shrub-like plant native to Central Asia and Mongolia. (livingwellmagazine.net)
  • The medical history of amphetamine-like compounds extends back over a century, beginning with the identification of ephedrine as the active ingredient in extracts from the Ephedra sinica shrub, which had long been used in traditional Chinese and Indian medicine. (medscape.com)
Pseudoephedrine1
Medicinal3
  • The Ephedra Plant offers many medicinal benefits besides weight loss, by raising your metabolism and heart rate. (mysupplementstore.com)
  • The most frequently mentioned medicinal herb was Ephedra sinica (7 cases) and the most commonly reported AEs were abdominal pain (8 cases), dizziness (6 cases), diarrhea (5 cases), and vomiting (5 cases) were followed in order. (jkom.org)
  • The extract form Ephedra has been used in China for medicinal purposes for several thousand years. (ncats.io)
Genus4
  • Chinese medicine Ephedra (the genus of plants) Ephedra (US-specific page on ephedrine-containing dietary supplements, observed (negative) health effects of these, and corresponding regulatory actions toward them) List of herbs with known adverse effects Bell, A. & Bachman, S. (2011). (wikipedia.org)
  • However, in some instances, mormon tea commercialized products are being adulterated by other Ephedra genus plants, which contain Ephedrine. (herbconer.com)
  • Be careful to read each label to see if the product is of other Ephedra genus plants or purely Ephedra nevadensis. (herbconer.com)
  • Although Ephedra nevadensis is from the same genus as Ephedra sinica and Ephedra major, it does not contain the chemical ephedrine. (ndgbotanicals.com)
Alkaloids8
  • The U.S. Food and Drug Administration (FDA) banned the sale of dietary supplements containing ephedrine alkaloids (stimulant compounds found in Ephedra sinica and some other plants) in the United States in 2004. (nih.gov)
  • This document summarizes the results of an evidence-based review on the efficacy and safety of ephedra and ephedrine alkaloids for weight loss or to enhance athletic performance (power and endurance). (nih.gov)
  • The FDA requested an independent review of reports of adverse events related to the use of supplements that contained ephedra alkaloids to assess causation and to estimate the level of risk the use of these supplements poses to consumers. (nih.gov)
  • We reviewed 140 reports of adverse events related to the use of dietary supplements containing ephedra alkaloids that were submitted to the FDA between June 1, 1997, and March 31, 1999. (nih.gov)
  • Thirty-one percent of cases were considered to be definitely or probably related to the use of supplements containing ephedra alkaloids, and 31 percent were deemed to be possibly related. (nih.gov)
  • Among the adverse events that were deemed definitely, probably, or possibly related to the use of supplements containing ephedra alkaloids, 47 percent involved cardiovascular symptoms and 18 percent involved the central nervous system. (nih.gov)
  • Dietary supplements containing ephedrine alkaloids from herbal sources (ephedra) are brought to the attention of the CSWG as part of an ongoing National Institutes of Health (NIH) Office of Dietary Supplements (ODS) research initiative on the safety and efficacy of these products. (nih.gov)
  • Some agents, often components of herbal preparations at far greater concentrations than the ephedrine alkaloids, may profoundly influence the toxicity attributed to ephedra supplements. (nih.gov)
Alkaloid4
  • The pharmacologic activity of an ephedra sample depends on its alkaloid composition. (nih.gov)
  • For patients with a history of benign prostate hyperplasia, the author will first consult the Chinese Medicine team to establish whether any herbal medicine has the ingredient ephedra alkaloid (麻黃). (hkmj.org)
  • Concern that naturally occurring non-ephedrine alkaloid constituents of Ephedra spp. (nih.gov)
  • Ephedrine (l-form) is an alkaloid, which was initially purified from Ephedra plant. (ncats.io)
Chromium picolinate1
  • Ephedra-containing performance enhancers often contain caffeine and other ingredients, such as chromium picolinate or l -carnitine, and may be consumed with other performance enhancers, such as androstenedione and creatine monohydrate. (nih.gov)
Seeds2
  • In traditional medicines also, Ephedra roots, stem bark, leaves, and even seeds are being used to make infusions for treating kidney diseases. (herbconer.com)
  • Once mature, Ephedra nevadensis will begin to produce clusters of yellow flowers that will eventually lead to the development of small cones that contain the seeds. (ndgbotanicals.com)
Extract3
Toxicity1
Botanical1
  • Although this analysis raises concerns about the safety of botanical dietary supplements containing ephedra, most of these case reports are not documented sufficiently to support an informed judgment about the relationship between the use of ephedra-containing dietary supplements or ephedrine and the adverse event in question. (nih.gov)
Nevadensis4
Intermedia1
Herb3
  • Ephedra is an herb and Chinese folk medicine with evidence for weight loss, but owing to concerns about adverse health effects, including cardiovascular, psychiatric, and neurologic consequences, it was banned by the US Food and Drug Administration (FDA) in 2004. (medscape.com)
  • Ephedra is a strongly stimulant, acrid-tasting herb that has a central place in Chinese and other herbal traditions. (herbsandremedies.club)
  • Ephedra has been banned in the U.S. due to frequent abuse of the herb, as an amphetamine-type "high" and, at excessive dosage, in weight-loss regimens. (herbsandremedies.club)
Dietary supplements10
  • Prior to the ban, ephedra was an ingredient in some dietary supplements promoted for weight loss, increased energy, and enhanced athletic performance. (nih.gov)
  • Almost no new research on ephedra has been performed in the years since its use in dietary supplements was banned in the United States. (nih.gov)
  • Prior to the ban, research showed that dietary supplements containing ephedra/ephedrine (usually in combination with caffeine) had modest short-term effects on weight loss. (nih.gov)
  • The use of ephedrine, ephedrine plus caffeine, or dietary supplements containing ephedra and botanicals with caffeine is associated with a modest but statistically significant increase in weight loss over a relatively short time (less than or equal to 6 months). (nih.gov)
  • No studies have assessed the effect of dietary supplements containing ephedra and botanicals on athletic performance. (nih.gov)
  • RAND analyzed adverse event reports filed with the U.S. Food and Drug Administration (FDA) and with a manufacturer of ephedra-containing dietary supplements as well as published case reports. (nih.gov)
  • In 2004, the FDA banned the U.S. sale of dietary supplements containing ephedra. (livingwellmagazine.net)
  • Ephedra use may lead to serious health problems when used with other dietary supplements or medicines. (livingwellmagazine.net)
  • As the Senate Committee noted, the number of Americans taking dietary supplements containing ephedra has risen dramatically. (nih.gov)
  • Dr. Paul Coates, Director of the NIH Office of Dietary Supplements, provided information on existing studies of ephedra. (nih.gov)
Stems1
  • Chemical constituents of the stems of Ephedra sinica. (hkmj.org)
Stimulant1
  • Constitution End-piece Products inaugurate containing caffeine and ephedra/ephedrine were inaugurate to be more efficient in compensation Power Escape and Energy Boosting then Just Ma Haung by Itself, The Consummate ‚lan Stimulant Combo Ephedra & Caffeine. (estranky.cz)
Plant1
  • An ointment made from Ephedra plant may be applied topically as well, to hasten the time it would take to complete wound closure. (herbconer.com)
Supplements7
  • In 2004, the FDA banned the use of ephedra in nutritional supplements and the composition of Hydroxycut was altered, with removal of ephedra. (nih.gov)
  • You might remember that in 2004, the FDA actually banned ephedra-containing dietary and performance-enhancing supplements. (theconversation.com)
  • Ban against ephedra supplements at any does upheld. (vitanetonline.com)
  • Can I Stack Ephedra With Other Weight Loss Supplements? (mysupplementstore.com)
  • Ephedra can be stacked with other weight loss supplements like Hi-Tech CLA, As long as the product you are stacking with ephedra doesn't contain stimulants, you will be fine. (mysupplementstore.com)
  • The products listed are the most popular stacking partners for ephedra weight loss supplements. (mysupplementstore.com)
  • The nomination of ephedra containing supplements to the National Toxicology Program (NTP) is part of the expanded effort by the ODS. (nih.gov)
Rarely gives rise to side effects1
Caffeine and ephedra1
  • Initial ingredients in the products included caffeine and ephedra which in animal studies led to weight loss. (nih.gov)
Athletic performance1
Asthma4
  • Today, ephedra is used in the West and in China for problems ranging from chills and fevers to asthma and hay fever. (herbsandremedies.club)
  • Ephedra is used principally in current Western herbal medicine as a treatment for asthma and hay fever, and for the acute onset of colds and flu. (herbsandremedies.club)
  • Ephedra does not cure asthma but in many cases it is very effective in treating the symptoms and thus making life somewhat easier for the sufferer. (pfaf.org)
  • What Ephedra Is Used For Ephedra has been used for more than 5,000 years in China and India to treat conditions such as colds, fever, flu, headaches, asthma, wheezing, and nasal congestion. (livingwellmagazine.net)
Found7
  • Ephedra has been found to activate beta-adrenergic receptors and stimulate thermogenesis in brown adipose tissue, resulting in weight loss. (medscape.com)
  • [ 8 ] Ephedra has been commonly found in combination with caffeine and aspirin, which appear to acts synergistically with ephedra to enhance weight loss. (medscape.com)
  • Before the FDA's 2004 ban of ephedra, a review published in JAMA [ 10 ] found that ephedra was associated with modest, short-term weight loss averaging 0.9 kg/mo. (medscape.com)
  • An NCCAM-funded study that analyzed phone calls to poison control centers found a higher rate of side effects from ephedra, compared with other herbal products. (livingwellmagazine.net)
  • Other studies and systematic reviews have found an increased risk of heart, psychiatric, and gastrointestinal problems, as well as high blood pressure and stroke, with ephedra use. (livingwellmagazine.net)
  • A phenethylamine found in EPHEDRA SINICA. (bvsalud.org)
  • What Other Ingredients Are Commonly Found In Ephedra Products & Stacks? (mysupplementstore.com)
Diuretics2
  • My Supplement Store sells energy drinks and gels, fat burners, diuretics, and ephedra products. (mysupplementstore.com)
  • Ephedra-based diet aids often contain other stimulants, such as caffeine (guarana), as well as salicin, diuretics, and cathartics. (nih.gov)
Stimulants1
  • People with a history of cardiovascular disease, those taking high doses of ephedra, and those taking it in combination with other stimulants such as caffeine would be expected to be at increased risk, but some of the severe events occurred in people with no preexisting medical problems, people taking relatively low doses of ephedra, or people taking ephedra alone. (nih.gov)
Botanicals1
  • Results of controlled trials show that the use of synthetic ephedrine, ephedrine plus caffeine, or ephedra plus botanicals containing caffeine is associated with 2-3 times the risk of nausea, vomiting, psychiatric symptoms such as anxiety and change in mood, autonomic hyperactivity, and palpitations compared with placebo. (nih.gov)
Products7
  • According to the RAND report, the number of deaths, myocardial infarctions, cerebrovascular accidents, seizures, and serious psychiatric illnesses in young adults is sufficient to warrant further evaluation of the safety of these products in a controlled manner (such as a hypothesis-testing case-control study) to test the possibility that consumption of ephedra or ephedrine causes these serious adverse events. (nih.gov)
  • In 2004, Hydroxycut products containing ephedra were withdrawn from use in the United States because of cardiovascular risks and in 2009 because of hepatotoxicity. (nih.gov)
  • Although evidence of modest weight loss secondary to ephedra-caffeine ingestion exists, potentially serious adverse effects have led the U.S. Food and Drug Administration to ban the sale of these products. (aafp.org)
  • Products containing ephedra should be taken about 1 hour before meals and workouts. (mysupplementstore.com)
  • We currently offer 11 ephedra products. (mysupplementstore.com)
  • Both men and women can take ephedra products. (mysupplementstore.com)
  • Ephedra is an effective stand-alone weight loss supplement, but when combined with other products its effectiveness works even more efficiently. (mysupplementstore.com)
Cardiovascular disease1
China2
  • Native to northern China and Inner Mongolia, ephedra often grows in desert areas. (herbsandremedies.club)
  • In China, ephedra is popular for chills and fevers, coughs and wheezing, and in combination with rehmannia (Rehmannia glutinosa) it is given to treat kidney yin deficiency. (herbsandremedies.club)
Efficacy1
  • Although ephedra has had some efficacy as a nutraceutical weight-loss agent, at least in the short term, it is not considered safe and therefore should not be recommended to patients as an aid to weight loss. (medscape.com)
Mormon1
Combination2
  • Caffeine has been shown to have a synergistic effect on weight loss when used in combination with either ephedra or polyphenols. (medscape.com)
  • 4 Metabolife 356, an ephedra-containing combination supplement, was the top-selling diet supplement with $70 million in sales, representing a 127 percent increase from sales in 2000. (aafp.org)
Potentially serious1
Long1
  • Ephedra may be effective in promoting weight loss when taken for up to 6 months, however it's unclear whether this benefit will continue long-term. (pharmachoice.com)
Weight1
  • In addition to its synergistic effect with polyphenols and ephedra, caffeine may play a role in weight loss through indirect mechanisms. (medscape.com)