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Trichomonas vaginalisTrichomonas VaginitisTrichomonasTrichomonas InfectionsAntitrichomonal AgentsVaginaMetronidazoleTritrichomonas foetusParasitologyVaginal DischargeLeukorrheaPyruvate SynthaseSexually Transmitted DiseasesVaginosis, BacterialVaginitisGardnerella vaginalisGonorrheaGiardia lambliaUrethritisAntiprotozoal AgentsOrnidazoleCandidiasis, VulvovaginalProtozoan ProteinsTritrichomonasTinidazoleDNA, ProtozoanTrichomonadidaMycoplasma hominisVaginal SmearsVaginal DiseasesChlamydia trachomatisAmebicidesNeisseria gonorrhoeaeChlamydia InfectionsMycoplasma genitaliumTotiviridaeSpecimen HandlingOrganellesUrineGenes, ProtozoanEntamoebaNifuratelNew OrleansReproductive Tract InfectionsLung Diseases, ParasiticCulture MediaRNA VirusesSexually Transmitted Diseases, BacterialGiardiaDichlorophenEncyclopedias as TopicProtozoan Infections
ProtozoaBacterial vaginosisEntamoebaChlamydiaVaginalis infectionGiardiaInfectionImmunoassayAnaerobicGlycolytic enzymesParasitic protozoanPathogensTrichomonadsAssayNucleicAntigensHerpesVaginalCytosolicSpeciesInhibitionBiosynthesisTrichomoniasisInfectionsSecretionAmplificationDetectionInsightsCervicalTargetsMolecular weightFoundOccursSymptomsTestActivityCapableMainDirectActivationCellsApproximatelyRangeControlStep
Protozoa4
Bacterial vaginosis2
Entamoeba5
  • Entamoeba histolytica , Giardia duodenalis , and Trichomonas vaginalis . (cdc.gov)
  • This study analyzed the incidence of Entamoeba gingivalis and Trichomonas tenax in samples of dental biofilm and saliva from patients with gingivitis / periodontitis and in healthy subjects. (bvsalud.org)
  • These findings suggest that Entamoeba gingivalis more common in the early stages of periodontitis, while Trichomonas tenax is considered a protozoan of the gingival sulcus. (bvsalud.org)
  • Analisar a incidência de Entamoeba gingivalis e Trichomonas tenax em amostras de biofilme dental e saliva de pacientes com gengivite/periodontite e de indivíduos saudáveis. (bvsalud.org)
  • Estes achados sugerem que a Entamoeba gingivalis aparece mais em estágios iniciais da periodontite, enquanto que o Trichomonas tenax é considerado um protozoário do sulco gengival. (bvsalud.org)
Chlamydia1
  • The BD Viper System also allows laboratories to test samples in panel mode for T. vaginalis , C. trachomatis , and N. gonorrhea , or in batch mode for chlamydia and gonorrhea, trichomonas, and herpes on the same automated platform. (aacc.org)
Vaginalis infection1
  • Trichomonas vaginalis infection in males has been found to cause asymptomatic urethritis and prostatitis. (wikipedia.org)
Giardia2
Infection9
  • Trichomonas vaginalis, a parasitic protozoan, is the etiologic agent of trichomoniasis, and is a sexually transmitted infection. (wikipedia.org)
  • The possible contribution of mucin degrading enzymes to the pathogenesis of infection is, therefore, not to be underestimated. (bmj.com)
  • 2) Symptoms of Trichomonas infection in birds (symptoms of canker disease). (pet-informed-veterinary-advice-online.com)
  • Trichomonas vaginalis is the most common non-viral sexually transmitted infection. (cdc.gov)
  • Trichomonas vaginalis is likely the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in the United States. (cdc.gov)
  • A randomized controlled trial in HIV-uninfected women demonstrated that multidose metronidazole 500 mg twice daily for 7 days reduced the proportion of women with Trichomonas infection at 1 month test of cure compared with women receiving single-dose therapy (2 g). (cdc.gov)
  • The tincture was able to reduce both the rate of growth and the rate of reproduction of Trichomonas vaginalis , and was found to be effective in halting the recurrence of Candida albicans infection. (beauty104.com.tw)
  • It seems to prevent infection and repair tissue damaged by infection, partially through inhibiting the activity of the enzyme hyaluronidase. (beauty104.com.tw)
  • Trichomonas vaginalis (TV) is a flagellated protozoan parasite of the genital tract causing trichomoniasis, a common sexually transmitted infection (STI) affecting men and women [ 1 , 2 ]. (biomedcentral.com)
Immunoassay1
  • Since fecal examination is very labor-intensive and requires a skilled microscopist, antigen detection tests have been developed as alternatives using direct fluorescent antibody (DFA), enzyme immunoassay (EIA), and rapid, dipstick-like tests. (cdc.gov)
Anaerobic3
  • Trichomonas vaginalis is an anaerobic, flagellated protozoan parasite and the causative agent of a sexually transmitted disease called trichomoniasis. (wikipedia.org)
  • These adaptations include reduction or elimination of most mitochondrial metabolic pathways and the use of oxidative stress enzymes generally associated with anaerobic prokaryotes. (jcvi.org)
  • Homocysteine alpha,gamma-lyase from the anaerobic protozoan parasite Trichomonas vaginalis has been cloned from genomic DNA using PCR methods and expressed in Escherichia coli with a vector containing the T7 promoter. (unipr.it)
Glycolytic enzymes2
  • therefore, they may be targets for many diverse proteolytic and glycolytic enzymes. (bmj.com)
  • Fermentation of cellulosic biomass goes through an atypical glycolytic pathway in this thermophilic bacterium, with various glycolytic enzymes capable of utilizing different phosphate donors, including GTP and inorganic pyrophosphate (PP i ), in addition to or in place of the usual ATP. (biomedcentral.com)
Parasitic protozoan1
  • The most pervasive nonviral sexually transmitted disease, a parasitic protozoan known as Trichomonas vaginalis (T. vaginalis), poses a deadly and intensifying threat. (adelphi.edu)
Pathogens1
  • 25 Tests) Detects elevated vaginal fluid sialidase activity, an enzyme produced by bacterial pathogens associated wit. (cliawaived.com)
Trichomonads2
Assay3
  • FDA has cleared BD Diagnostics' BD ProbeTec Trichomonas vaginalis Qx Amplified DNA Assay for the diagnosis of trichomoniasis on the BD Viper System with XTR Technology. (aacc.org)
  • 25 Tests) The OSOM Trichomonas Rapid Test is an immunochro-matographic assay that detects pathogen antigens directly f. (cliawaived.com)
  • The artus T. vaginalis QS-RGQ Kit is an in vitro real-time PCR assay for the direct qualitative detection of Trichomonas vaginalis DNA purified from clinician-collected vaginal swabs, endocervical swabs, and urine samples (male and female) from symptomatic and asymptomatic subjects as an aid in the diagnosis of trichomoniasis. (qiagen.com)
Nucleic2
  • The specific primers and specific fluorescent probes are designed for the nucleic acid conserved region of Trichomonas vaginalis (TV). (biokeyqpcr.com)
  • Of the five approaches, the assays that provide the most rapid diagnosis, specifically the detection of antibodies by rapid serologic methods, and specific detection of cellular components, including antigens, enzymes, or nucleic acid sequences (especially with amplification), have gained the most acceptance. (meridianbioscience.com)
Antigens1
Herpes1
Vaginal1
Cytosolic3
  • Methionine adenosyltransferase (MAT) is a cytosolic ubiquitous enzyme that synthesizes S-adenosyl-L-methionine (SAM), a molecule that is one of the most important metabolites in living cells. (biomedcentral.com)
  • A cytosolic ferredoxin-independent hydrogenase possibly mediates hydrogen uptake in Trichomonas vaginalis. (cuni.cz)
  • Type B enzymes are distant from Type A Class II aldolases, which consists of a number of bacterial and fungal enzymes and also contains the cytosolic FBA of Euglena gracilis. (ncl.ac.uk)
Species5
  • Trichomonas gallinae is a protozoan organism that is commonly found in the mouth, throat, gastro-intestinal tract and upper respiratory tract of pigeons, doves, turkeys, chickens, canaries, raptors (birds of prey) and a variety of psittacine (parrot) bird species including budgerigars, cockatiels and Amazon parrots. (pet-informed-veterinary-advice-online.com)
  • Avian Trichomonas is a parasitic organism that infests the upper gastro-intestinal tract (esophagus, crop and proventriculus), mouth, oropharynx (throat region) and upper respiratory tract of a range of different bird species. (pet-informed-veterinary-advice-online.com)
  • The species of Trichomonas that affects birds including: pigeons, doves, turkeys, chickens, canaries, raptors (birds of prey), various parrot species (e.g. budgerigars, cockatiels and Amazon parrots) as well as certain other types of birds is called Trichomonas gallinae (there is also another species of Trichomonas that affects pigeons, which is called Trichomonas columbae ). (pet-informed-veterinary-advice-online.com)
  • The various Trichomonas species (there are many species of Trichomonas in addition to T. gallinae ) have distinct clumps of flagella protruding from the anterior end of their bodies (the exact number of flagella present is one clue scientists use to determine the particular species of a Trichomonas organism that they have found). (pet-informed-veterinary-advice-online.com)
  • Depending on the species of Trichomonas you are looking at, physical differences may exist in such features as: the number of anterior flagella, the size and length of the undulating membrane, the size and shape and position of the parabasal body and the length of the axostyle. (pet-informed-veterinary-advice-online.com)
Inhibition3
  • Terbinafine is an Allylamine antifungal that inhibits biosynthesis of Ergosterol (an essential components if fungal cell membrane) via inhibition of Squalene Epoxidase enzyme causing fungal cell death. (medeasy.health)
  • The mechanism of action is associated with inhibition of COX activity - the main enzyme metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. (medicatione.com)
  • The mechanism of action associated with inhibition of the enzyme COX, which leads to inhibition of prostaglandin synthesis from arachidonic acid. (medicatione.com)
Biosynthesis2
  • Actinomycetes lack the enzymes for GSH biosynthesis, but as a substitute, they utilize alternative low molecular weight thiols (LMW), such as bacillithiol (BSH) and MSH, ergothioneine (ESH) [ 1 ] . (encyclopedia.pub)
  • MSH biosynthesis involves five enzymes, and the substrates myo -inositol-1-phosphate (Ins-P), UDP- N -acetyl glucosamine (UDP-GlcNAc), and Cysteine (Cys) represented in Figure 1 . (encyclopedia.pub)
Trichomoniasis3
Infections2
  • Ornidazole belongs to the nitroimidazole group of antibiotics and is used to treat amoeba and trichomonas infections. (medeasy.health)
  • Our results could provide useful insights for targeting related enzymes," Dr. Stockman explained, "and the most potent compounds discovered may also be broadly applicable to infections caused by related parasites. (adelphi.edu)
Secretion1
  • Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases. (cuni.cz)
Amplification1
  • The artus T. vaginalis QS-RGQ Kit contains reagents and enzymes for the specific amplification and direct detection of a multiple repeat region within T. vaginalis genomic DNA. (qiagen.com)
Detection1
Insights1
  • 2014 ) Rubrerythrin from Trichomonas vaginalis- structural insights into its mechanism of action Acta Crystallographica Section a Foundations and Advances . (academictree.org)
Cervical2
  • The role of hydrolytic enzymes in the pathogenesis of sexually transmitted diseases and their effect on cervical mucus are discussed in this review. (bmj.com)
  • 1, 2 This review approaches the role of mucin degrading enzymes from the potential interaction of micro-organisms with the cervical mucus barrier, and discusses the contribution that mucin degrading enzymes may make to microbial colonisation of the reproductive tract. (bmj.com)
Targets1
  • It will take at least three to four more years to evaluate whether these two enzymes are viable drug targets," Dr. Stockman said. (adelphi.edu)
Molecular weight2
  • Mucinases are enzymes capable of degrading mucins (the complex high molecular weight molecules that are the major non-aqueous components of mucous gels). (bmj.com)
  • The enzyme is a homotetramer with a monomer molecular weight of 43K and contains pyridoxal phosphate. (unipr.it)
Found3
  • Numerous publications were found describing the production of hydrolytic enzymes in sexually transmitted diseases. (bmj.com)
  • Trichomonas tenax was found in 22.53% of the biofilm samples (16.66% from gingivitis, 41.67% from periodontitis and 41.67% from healthy patients) and 9.81% of the saliva samples (20% from gingivitis, 40% from periodontitis and 40% from healthy patients).The presence of these microorganisms was related to the type of periodontal disease (p=0.001), but not with age (p=0.178) or risk factors (p=0.194). (bvsalud.org)
  • The first marinerelement transposons outside of animals were found in trichomonas vaginalis. (web.app)
Occurs1
  • Methionine adenosyltransferase (MAT) is a ubiquitous essential enzyme that, in eukaryotes, occurs in two relatively divergent paralogues: MAT and MATX. (biomedcentral.com)
Symptoms2
  • Trichomonas disease symptoms, modes of transmission (means of disease spread), medical treatment options and tips for ongoing Trichomonas prevention are all included, along with information on how to diagnose the condition. (pet-informed-veterinary-advice-online.com)
  • Testing for Trichomonas is too often neglected, but recommended, for recurrent or persistent symptoms. (medscape.com)
Test1
  • In what represented the first known application of fragment screening to ribohydrolase enzymes, he would test a diverse set of chemical compounds to see which ones had the intended effect. (adelphi.edu)
Activity3
  • The enzyme catalyses the template-dependent polymerization of nucleotides into duplex DNA in the 5'→3' direction and also exhibits 5' exonuclease activity. (kleverlab.eu)
  • The Trichomonas rHCYase is selective for homocysteine with respect to very low cysteinase activity in contrast to the alpha,gamma-lyase from Pseudomonas putida, which has very high cysteinase activity with respect to homocysteine. (unipr.it)
  • Helps with depression (inhibitor of the activity of an enzyme known as monoamine oxidases MAO used in antidepressants) and with immune and immunosuppressive disorders, e.g. (vitacare-biotechnology.co.nz)
Capable1
Main1
Direct1
  • Partial or complete degradation of mucin molecules by microbial enzymes is often a fundamental step in disruption of defensive mucosal barriers, as these constitute direct interfaces between internal and external environments. (bmj.com)
Activation1
  • MSH maintains the intracellular redox homeostasis, allowing the appropriate working of many biological processes, counting enzyme activation, DNA synthesis, and cell-cycle regulation. (encyclopedia.pub)
Cells2
  • And because the parasite cannot generate them on its own, "T. vaginalis must scavenge them from host cells using nucleoside salvage pathway enzymes," Dr. Stockman said. (adelphi.edu)
  • This process requires an enzyme a transposase that is encoded within some of these transposons fig. Protocoi for piggybac integration into target cells 1. (web.app)
Approximately3
  • We now demonstrate that this enzyme can also phosphorylate sedoheptulose-7-phosphate (an intermediate in the pentose phosphate pathway), with the V max and K m of F6P being approximately 15 folds higher and 43 folds lower, respectively, in comparison to sedoheptulose-7-phosphate. (biomedcentral.com)
  • The enzyme was purified to approximately 90% purity using heat treatment at 50 degreesC, precipitation steps with polyethyleneimine, polyethylene glycol 8000, and high sodium chloride, DEAE-Sepharose FF chromatography, and phenyl-Sepharose 6 FF chromatography. (unipr.it)
  • The CYP2C19 enzyme metabolizes approximately 15% of all prescribed drugs. (aacc.org)
Range1
  • In order to breach this barrier, micro-organisms may produce a range of hydrolysing enzymes called mucinases. (bmj.com)
Control1
Step1
  • Enzyme is activated by 15 min incubation step at 95°C. This prevents the extension of non-specifically annealed primers and primer-dimers formed at low temperatures during the PCR setup. (kleverlab.eu)