• The effects of vacuum packaging on browning, phenolic content, the enzyme activity of phenylalanine ammonia lyase (PAL), polyphenol oxidase (PPO), and peroxidase (POD), and PPO , PAL , POD , and ERF genes expression in fresh-cut lotus root were studied. (ashs.org)
  • This polyphenolic compound is known to be a strong anti-oxidant which scavenges reactive oxygen species (ROS) directly or effectively inhibits ROS-generating enzymes ( e.g. xanthine oxidase, lipoxygenase). (rsc.org)
  • 5,5-Dithiobis(2-nitrobenzoic acid) pyrene derivative-carbon nanotube electrodes for NADH electrooxidation and oriented immobilization of multicopper oxidases for the development of glucose/O2 biofuel cells. (univ-grenoble-alpes.fr)
  • Substrates containing a -COOH group are inhibitors for catechol oxidase. (lookformedical.com)
  • I advanced understanding of the contribution of metals to enzyme-catalysed reactions and employed state-of-the-art technologies ( e.g. cryo-EM, ancestral gene reconstruction) to develop enzyme inhibitors as leads for novel biocides (herbicides, fungicides, antibacterial compounds) and engineer enzymes with enhanced catalytic properties for industrial applications in the advanced manufacturing sector ( i.e. cell-free enzyme cascades, next-gen fertilisers). (edu.au)
  • In vitro production of enzymatically active O. volvulus prolyl 4-hydroxylase should facilitate identification of specific inhibitors of the parasite enzyme. (embl.de)
  • Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Human Oxyntomodulin (OXM) in samples from Serum, plasma and other biological fluids with no significant corss-reactivity with analogues from other species. (tuberculosisdrugresearch.org)
  • Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Multimerin 2 (MMRN2) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids. (youngresearch.eu)
  • Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Dynein Heavy Chain Domain Containing Protein 1 (DNHD1) in samples from Tissue homogenates and other biological fluids. (youngresearch.eu)
  • The detection and quantitation method consists of an enzyme-linked immunosorbent assay ( ELISA ). (kits-elisa.com)
  • The enzyme catalyzes the oxidation of o-diphenols to o-quinones without hydroxylating monophenols, the additional activity of tyrosinase. (lookformedical.com)
  • The enzyme polyphenol oxidase (PPO) is nearly ubiquitous in Kingdom Plantae and catalyzes the oxidation of phenolic compounds into highly reactive quinones. (ashs.org)
  • Substrate specificity of catechol oxidase from Lycopus europaeus and characterization of the bioproducts of enzymic caffeic acid oxidation. (lookformedical.com)
  • 12,13 However, its catechol structure ( o -dihydroxyl structure in the B-ring) leads to pro-oxidant properties by generating ROS during its oxidation process, which may result in quinone toxicity. (rsc.org)
  • The genes/ enzymes (CYP2D6, COMT and PNMT) that are involved in the biosynthesis of morphine have variations that affect their functionality. (nel.edu)
  • protein_coding" "AAC74185","ptsG","Escherichia coli","fused glucose-specific PTS enzymes: IIB component/IIC component [Ensembl]. (ntu.edu.sg)
  • Glucose sensor based on magnetic particles (MPs) with immobilized enzymes glucose oxidase (GOx) and horseradish peroxidase (HRP) was developed and the GOx catalyzed reaction was visualized by a smart-phone-integrated camera. (nel.edu)
  • The presented assay showed complying results with reference method (standard spectrophotometry based on enzymes glucose oxidase and peroxidase inside plastic cuvettes) with linear dependence and correlation coefficient 0.999 in concentration range between 0 and 4 mmol/l. (nel.edu)
  • 14,15 Conversely, its pro-oxidant activity may enhance cellular defence against oxidants by stimulating the redox-regulated signal transduction pathway which leads to the gene expression of anti-oxidative enzymes such as heme oxygenase-1 (HO-1) and glutathione peroxidase (GPx). (rsc.org)
  • In cells , antioxidants such as glutathione , mycothiol or bacillithiol , and enzyme systems like superoxide dismutase , can prevent damage from oxidative stress . (wikipedia.org)
  • Molecular phylogenetic analysis, tests on growth characteristics, enzyme assays, and comparative analysis of volatile compounds, were carried out for this purpose. (springer.com)
  • It is a complex of copper-containing proteins that acts also on a variety of substituted catechols. (lookformedical.com)
  • It is likely to act as a bioactive compound by exerting reactive oxygen species (ROS)-scavenging activity and/or binding to specific proteins such as oxidative enzymes and transcriptional factors in signal transduction pathways. (rsc.org)
  • NAD(P)H:quinone reductase (NQO1) and other antioxidant enzymes, whose gene expression are commonly under the regulation of the transcription factor Nrf2, can serve as target proteins utilized toward development of disease-modifying therapy for PD. (en-journal.org)
  • I have successfully focused my research on the investigation of enzyme-catalysed reactions, their optimisation for applications in biotechnology and the synthesis of small molecules that mimic their structure and catalytic function ( i.e. biomimetics). (edu.au)
  • They completed this by tailoring the exosome surfaces with molecules known as catechol, which is a chelating agent that types complexes with metallic ions. (myspaceastronomy.com)
  • Because of the presence of ROS-generating enzymes such as tyrosine hydroxylase and monoamine oxidase, the DAergic neurons are particularly prone to oxidative stress. (en-journal.org)
  • Clinical case of extremely elevated levels of alkaline phosphatase (ALP) enzyme detected in the 3rd trimester of gestation, the diagnostic and therapeutic procedures, delivery and puerperium are presented. (nel.edu)
  • The complex-forming property of catechol permits them to drive fusions between exosomes when they're combined with metallic ions reminiscent of Fe 3+ . (myspaceastronomy.com)
  • This hypothesis was tested based on phylogenetic analysis of the rDNA ITS region, morphological characters of basidiomes and pure cultures, growth rates and optimum growth temperature experiments, mycelial confrontation tests, enzyme activity tests and volatile organic compound (VOC) production. (springer.com)
  • Enhanced peroxidase activity associated with the hypersensitive response of Solanum dulcamara to the ball mite Aceria cladophthirus (Acari: Eriophyoidea). (indianentomology.org)
  • Transgenic tobacco ( Nicotiana tabacum ) plants expressing jrPPO1 display greater than 10-fold increases in leaf PPO activity compared with wild-type tobacco, demonstrating that jrPPO1 encodes a functional enzyme. (ashs.org)
  • The enzyme responsible for collagen maturation is prolyl 4-hydroxylase, making this enzyme a central activity in cuticle biosynthesis and a potentially important chemotherapeutic target. (embl.de)
  • These findings highlight that synthetic metalloenzymes may provide an efficient tool for disentangling the role of axial ligand orientation over peroxidase activity. (ward-lab.ch)
  • 2000. A metabolite of methoxychlor, 2,2-bis( p hydroxyphenyl)-1,1,1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme. (cdc.gov)
  • This review highlights some of the functional differences in the critical enzymes required for the biosynthesis of morphine that may affect human health. (nel.edu)
  • My seminal work into enzyme mechanisms, regulation and engineering received international acclaim evidenced by invitations to provide plenary and keynote lectures and review articles in prestigious journals. (edu.au)
  • Alternative sites for cell density regulation of the enzyme could rely on its sensitivity to sulfhydryl groups. (embl.de)
  • protein_coding" "AAC74888","manY","Escherichia coli","mannose-specific enzyme IIC component of PTS [Ensembl]. (ntu.edu.sg)
  • An enzyme of the oxidoreductase class that catalyzes the reaction between catechol and oxygen to yield benzoquinone and water. (lookformedical.com)
  • The ability of bacterial laccases to be generated both intracellularly and extracellularly, with active enzymes across a broad pH and temperature range, was investigated. (biomedcentral.com)
  • Clinical Significance: Amylase also has medical history in the use of Pancreatic Enzyme Replacement Therapy (PERT). (wikipedia.org)
  • A. Bhagwat, F. Zhang, C.H. Collins, and J.S. Dordick (2021), "Influence of Bacterial Culture Medium on Peptidoglycan Binding of Cell Wall Lytic Enzymes," J. Biotechnol.330, 27-34. (rpi.edu)
  • A. Bhagwat, M. Mixon, C.H. Collins, and J.S. Dordick (2020), "Opportunities for Broadening the Application of Cell Wall Lytic Enzymes", Appl. (rpi.edu)
  • This was in flip achieved by attaching the catechol onto antibodies that concentrate on particular cell markers, reminiscent of CD9. (myspaceastronomy.com)
  • Feeding on poplar leaves by caterpillars potentiates foliar peroxidase action in their guts and increase plant resistance. (indianentomology.org)
  • High levels of 1-MHis tend to inhibit the enzyme carnosinase and increase anserine levels. (pathbank.org)
  • Laboratory tests showed elevated (as much as a 10.5-fold increase) values of alkaline phosphatase enzyme, 94.05% of which was placental isoenzyme. (nel.edu)
  • These compartments have a number of enzymes that work collectively to execute necessary mobile capabilities. (myspaceastronomy.com)
  • A survey of wound- and methyl jasmonate-induced leaf polyphenol oxidase in crop plants. (indianentomology.org)
  • In the biomedical, environmental, and food quality control, agricultural, and pharmaceutical industries, enzyme-based biosensors have become an important tool for qualitative and quantitative measurement of a variety of target analytes. (jpionline.org)
  • Defensive role of tomato Polyphenol oxidase against cotton bollworm ( Helicoverpa armigera ) and Beet armyworm ( Spodoptera exigua ). (indianentomology.org)
  • The foliar application of its crude formulation @ 108 spores ml-1 had significant influence on the induction of defense related enzymes and components against A. craccivora infestation in cowpea. (indianentomology.org)
  • Phase II enzymes present in the intestinal epithelial cells and the liver cells facilitate their metabolic conversion to glucuronide and sulfate conjugates. (rsc.org)