• Trifunctional enzyme subunit beta, mitochondrial (TP-beta) also known as 3-ketoacyl-CoA thiolase, acetyl-CoA acyltransferase, or beta-ketothiolase is an enzyme that in humans is encoded by the HADHB gene. (wikipedia.org)
  • HADHB is a subunit of the mitochondrial trifunctional protein and has thiolase activity. (wikipedia.org)
  • Trifunctional protein deficiency is characterized by decreased activity of long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD), long-chain enoyl-CoA hydratase, and long-chain thiolase. (wikipedia.org)
  • Beta-ketoadipyl CoA thiolase (EC 2.3.1. (lbl.gov)
  • 3-ketoacyl-CoA thiolase OS=Klebsiella pneumoniae subsp. (uu.nl)
  • 3-ketoacyl-CoA thiolase OS=Aeromonas hydrophila subsp. (uu.nl)
  • 3-ketoacyl-CoA thiolase OS=Marinomonas sp. (uu.nl)
  • ATP synthase, alpha subunit, C-terminal [Interproscan]. (ntu.edu.sg)
  • ATP synthase peripheral stalk subunit. (gsea-msigdb.org)
  • 18874) imidazoleglycerol phosphate synthase%2C cyclase subunit CP001857 CDS Arcpr_0021 19046. (go.jp)
  • This gene encodes the beta subunit of the mitochondrial trifunctional protein, a catalyst of mitochondrial beta-oxidation of long chain fatty acids. (wikipedia.org)
  • The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. (wikipedia.org)
  • Nitrate reductase delta subunit [Interproscan]. (ntu.edu.sg)
  • The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. (nih.gov)
  • It contains enoyl-CoA hydratase, long-chain-3-hydroxyacyl-CoA dehydrogenase, and acetyl-CoA C-acyltransferase activities and plays an important role in the metabolism of long chain FATTY ACIDS. (bvsalud.org)
  • The HADHB protein catalyzes the final step of beta-oxidation, in which 3-ketoacyl CoA is cleaved by the thiol group of another molecule of Coenzyme A. The thiol is inserted between C-2 and C-3, which yields an acetyl CoA molecule and an acyl CoA molecule, which is two carbons shorter. (wikipedia.org)
  • The substrate specificities of different NAT enzymes are mainly determined by the identities of the first two N-terminal residues of the target protein. (hmdb.ca)
  • 16465618 ). In addition to the NAT enzymes and protein-based acetylation, N-acetylation of free glutamine can also occur. (hmdb.ca)
  • protein_coding" "Cz12g19130.t1","No alias","Chromochloris zofingiensis","Clp protease proteolytic subunit /Translocation-enhancing protein TepA [Interproscan]. (ntu.edu.sg)
  • SYP7 group Qc-type SNARE protein","protein_coding" "MA_10436714g0010","No alias","Picea abies","acyl-CoA thioesterase","protein_coding" "MA_135972g0010","No alias","Picea abies","Acyl-CoA-binding domain-containing protein 3 OS=Oryza sativa subsp. (ntu.edu.sg)
  • subunit alpha of MPP mitochondrial signal peptidase heterodimer","protein_coding" "Zm00001e017599_P001","No alias","Zea mays","Protein disulfide isomerase-like 2-2 OS=Oryza sativa subsp. (ntu.edu.sg)
  • GapMind searches the predicted proteins for candidates by using ublast (a fast alternative to protein BLAST) to find similarities to characterized proteins or by using HMMer to find similarities to enzyme models (usually from TIGRFams ). (lbl.gov)
  • Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam ). (lbl.gov)
  • protein_coding" "AAC74185","ptsG","Escherichia coli","fused glucose-specific PTS enzymes: IIB component/IIC component [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74323","adhE","Escherichia coli","fused acetaldehyde-CoA dehydrogenase/iron-dependent alcohol dehydrogenase/pyruvate-formate lyase deactivase [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74888","manY","Escherichia coli","mannose-specific enzyme IIC component of PTS [Ensembl]. (ntu.edu.sg)
  • A mitochondrial protein consisting of four alpha-subunits and four beta-subunits. (bvsalud.org)
  • Roles of hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha, a lipid metabolism enzyme, in Wilms tumor patients. (nih.gov)
  • Pyruvate dehydrogenase (PDH) is an enzyme complex that catalyzes the conversion of pyruvate into acetyl-coA in vivo. (biomedcentral.com)
  • The aim of this study was to clone the mRNA sequence of the Acyl-CoA dehydrogenase long chain ( ACADL ) gene of goats and explore the effect of ACADL on the differentiation of subcutaneous fat cells on this basis. (animbiosci.org)
  • 7524) oxaloacetate decarboxylase alpha subunit CP001857 CDS Arcpr_0006 complement(7556. (go.jp)
  • Through a series of chemical reactions of pyruvate decarboxylation, the glycolytic pathway (the final product is pyruvate) and the tricarboxylic acid cycle (the initial reactant is acetyl-coA) can be effectively connected [ 7 ]. (biomedcentral.com)
  • Functional annotation resulted in the identification of almost all genes involved in diverse lipid-metabolic pathways, including the novel fatty acid desaturase/epoxygenase, diacylglycerol acyltransferase 1 and 2, and phospholipid:diacylglycerol acyltransferases. (researchsquare.com)
  • 30054468 ). These enzymes consist of three main oligomeric complexes NatA, NatB, and NatC, which are composed of at least a unique catalytic subunit and one unique ribosomal anchor. (hmdb.ca)
  • This enzyme is usually homomeric, but I3R3D0 and I3RA71 are non-catalytic subunits of an enzyme from Haloferax mediterranei that also contains a "normal" catalytic subunit ( I3R3D1 , I3RA72 ). (lbl.gov)
  • This methylation is formed below with: an phosphorylation acetyl-CoA with an calcium maltose, a level with a setting a004614, a consistent domain with an alpha, and a process with A, water and actomyosin dynamics to occur these three melanocytes of loop. (evakoch.com)
  • Consequently, LW1564 promoted the phosphorylation of acetyl-CoA carboxylase, which inhibited lipid synthesis. (biomed.news)
  • 39504) translation initiation factor 2%2C alpha subunit CP001857 CDS Arcpr_0045 complement(39546. (go.jp)
  • Glycine-tRNA ligase, alpha subunit [Interproscan]. (ntu.edu.sg)
  • Malic enzyme, N-terminal domain [Interproscan]. (ntu.edu.sg)
  • DMSO reductase anchor subunit (DmsC) [Interproscan]. (ntu.edu.sg)
  • GINS subunit, domain A [Interproscan]. (ntu.edu.sg)
  • Two major QTLs, uuqA5-6 and uuqA5-7 , simultaneously affected the fatty acids, except C18:0, in most of environments, with the homologous genes fatty acid desaturase 2 ( FAD2 ) and glycerol-3-phosphate sn-2-acyltransferase 5 ( GPAT5 ) occurring in the confidence interval of uuqA5-6 , while phosphatidic acid phosphohydrolase 1 ( PAH1 ) was assigned to uuqA5-7 . (biomedcentral.com)
  • Histone acetyltransferases (HATs) neutralize the positive charge on lysine residues which interacts with the negative charge on Idarubicin HCl the DNA phosphate backbone through the addition of acetyl groups (for review see Kouzarides 2007 Day and Sweatt 2011 This has two main effects (Barrett and Wood 2008 First it physically relaxes chromatin structure which is conducive to gene expression. (biodiversityhotspot.org)
  • We found significant dysregulation of genes encoding drug-metabolizing enzymes and stress response components of the NRF2- mediated oxidative damage pathway, potentially representing key genes in African-American esophageal squamous carcinogenesis. (biomedcentral.com)
  • As subunits enzyme is, the E bacillus hormones tested by the G1 and S enzymes, are involved and the ions of the invalid visitors are. (evakoch.com)
  • Lysosomal enzyme tripeptidyl peptidase 1 destabilizes fibrillar Aβ by multiple endoproteolytic cleavages within the β-sheet domain. (uni-bielefeld.de)
  • N-Acetyl-L-glutamine (NAcGln) or N-Acetylglutamine, belongs to the class of organic compounds known as N-acyl-alpha amino acids. (hmdb.ca)
  • N-acetyl amino acids can be produced either via direct synthesis of specific N-acetyltransferases or via the proteolytic degradation of N-acetylated proteins by specific hydrolases. (hmdb.ca)
  • Furthermore, stearoyl-CoA desaturase-1 (SCD1), a transcriptional target of SREBP1, mediates the ferroptosis-suppressing activity of SREBP1 by producing monounsaturated fatty acids. (biomed.news)
  • 16465618 ). Aminoacylase I is a soluble homodimeric zinc binding enzyme that catalyzes the formation of free aliphatic amino acids from N-acetylated precursors. (hmdb.ca)
  • The download Hanging Sam: A Military Biography of General of Insulin like Growth Factor Binding Proteins( IGFBPs) phase 50 response pathway good research with reviewed N cell and C formation enzymes binding for conjugating Insulin like Growth Factors I and II( IGF I and IGF II). (evakoch.com)
  • GON7 subunit of KEOPS complex [Source. (gsea-msigdb.org)
  • The complex mainly consists of three enzymes, which are respectively called E1, E2 and E3 components of PDH according to the order in which they participate in the reactions. (biomedcentral.com)
  • 2013). Finally chromatin remodeling involves large multi-subunit complexes that can alter nucleosome positioning and the wrapping of DNA (reviewed in Hargreaves et al. (biodiversityhotspot.org)
  • As an important intermediate metabolite, acetyl-coA not only participates in tricarboxylic acid cycle as well as the glyoxylate cycle but also provides carbon source for the synthesis of mycolic acid and lipids [ 8 , 9 ]. (biomedcentral.com)
  • Decreases in these enzymes have been shown to lead to increased TAG production as fatty acid biosynthesis is favoured. (biomedcentral.com)
  • Palmityl-CoA, also known as palmitoyl CoA or CoA, palmitoyl, belongs to the class of organic compounds known as long-chain fatty acyl coas. (ymdb.ca)
  • this enzyme is involved in acetyl CoA production and has been linked to TAG accumulation in microalgae. (biomedcentral.com)