Enzyme protein that catalyzes fatty acetyl coa and acyl carrier protein carrier proteins. Medical search. Frequent questions

Palmitic acid, or hexadecanoic acid, is one of the most common saturated fatty acids found in animals, plants, and microorganisms. (hmdb.ca)
Palmitic acid is the first fatty acid produced during fatty acid synthesis and is the precursor to longer fatty acids. (hmdb.ca)
In catabolism, water is used to break bonds in order to generate smaller molecules (e.g. glucose, fatty acids and amino acids to be used for fuels for energy use or other purposes). (hmdb.ca)
Oleic acid, also known as oleate or 18:1 N-9, belongs to the class of organic compounds known as long-chain fatty acids. (ymdb.ca)
These are fatty acids with an aliphatic tail that contains between 13 and 21 carbon atoms. (ymdb.ca)
belongs to the class of organic compounds known as long-chain fatty acids. (ymdb.ca)
Fatty acids (FA) are essential monomeric components that define the structural diversity of lipids and determine their functional properties in the CNS. (encyclopedia.pub)
Next, palmitic acid is further elongated and desaturated to generate complex fatty acids. (encyclopedia.pub)
Moreover, transcripts representing fatty acid degradation were up-regulated indicating that fatty acids might be degraded to feed the increased need to channel carbons into fatty acid synthesis creating a futile cycle. (biomedcentral.com)
Even if amino acids are biologically present in a place, no protein can form spontaneously. (questionsonislam.com)
Fatty acids are the simplest fats synthesized in cells and they participate in the structure of complex fats that are to perform specific tasks in cells. (questionsonislam.com)
The most important feature that distinguishes fish oil from the fats of other living things is the long-chain polyunsaturated fatty acids. (questionsonislam.com)
Fatty acids are synthesized by considering special factors such as the physiology of the fish and the state of its environment. (questionsonislam.com)
The number and amount of fatty acids in fish oil varies according to many factors such as species, season, habitat and nutritional status. (questionsonislam.com)
c) It catalyzes the oxidative deamination of the unnatural (D-) forms of amino acids. (biologydiscussion.com)
c) It catalyzes the oxidative deamination of naturally occurring L-amino acids. (biologydiscussion.com)
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. (smpdb.ca)
This group of compounds includes amino acids and fatty acids. (lookformedical.com)
Twenty alpha-amino acids are the subunits which are polymerized to form proteins. (lookformedical.com)
The lipidomic analysis showed that disruption of NcACBP caused no obvious changes in the overall abundance and turnover of fatty acids while knockout resulted in the accumulation of triacylglycerol. (biomedcentral.com)
Fatty acids provide the acyl skeleton for lipid synthesis. (biomedcentral.com)
Before entering lipid synthesis pathways, different kinds of acyl-CoA transporters which acts as the major carrier of acyl-CoAs, such as fatty acid binding protein (FABP), sterol carrier protein 2 (SCP2) and acyl-CoA-binding protein (ACBP), would activate and convert fatty acids to fatty acyl-CoA esters via a reaction catalyzed by fatty acyl-CoA synthetase and transported to various metabolic locations [ 11 ]. (biomedcentral.com)
In addition, the function of many proteins is regulated by phosphorlylating serine, threonine or tyrosine amino acids. (histocutup.co.uk)
The main substrates that the body uses to liberate energy are carbohydrates (particularly glucose) and fatty acids. (histocutup.co.uk)
Amino acids can be employed in energy generation but as their main function is to form the building blocks of proteins catabolising them in energy production disrupts protein synthesis and therefore tends to be used only as a last resort. (histocutup.co.uk)
They are the site at which the Krebs cycle and beta-oxidation of fatty acids takes place. (histocutup.co.uk)
A group of 16-carbon fatty acids that contain no double bonds. (lookformedical.com)
Fatty acids are saturated and unsaturated (FATTY ACIDS, UNSATURATED). (lookformedical.com)
FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. (lookformedical.com)
These fatty acids are not in glycerol ester form. (lookformedical.com)
Covalent attachment of LIPIDS and FATTY ACIDS to other compounds and PROTEINS. (lookformedical.com)
Triglycerides are a type of fat found in the blood that are made up of three fatty acids and a glycerol molecule. (lookformedical.com)
A group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon. (lookformedical.com)
A group of compounds that are derivatives of octadecanoic acid which is one of the most abundant fatty acids found in animal lipids. (lookformedical.com)
State the physiological role of lysophospholipids & fatty acids produced by the breakdown of lecithin. (medical-junction.com)
2. Classify the fatty acids in details & indicate their physical properties. (medical-junction.com)
In mammals, however, a second energy source comes from the degradation of fatty acids, some of which are liberated from lipid reserves, for example in adipocytes. (biomedcentral.com)
Fatty acids, which are often found in chains as CoA-esters, are first transported across the outer mitochondrial membrane by palmitoyl transferase I, resulting in translocation to the intermembrane space and transformation into an acyl-carnitine form. (biomedcentral.com)
The apoptotic cell cargo contains amino acids, nucleotides, fatty acids, and cholesterol that function as metabolites and signaling molecules to bring about this re-programming. (biomed.news)
Protein and amino acids provide benefits in long-term or short-term explosive power activities. (peertechzpublications.org)
Krebs cycle) is an important aerobic pathway for the final steps of the oxidation of carbohydrates and fatty acids. (easyomics.org)
derived from glycolysis and pyruvate oxidation for carbohydrates and from beta oxidation of fatty acids. (easyomics.org)
Endogenous fatty acid synthesis is catalyzed by FASN, a human lipogenic enzyme capable of de novo synthesis of fatty acids [ 4 , 5 ]. (aging-us.com)

Then, Acetyl-CoA and malonyl-CoA are coupled to the acyl-carrier protein domain of the rate-limiting enzyme fatty acid synthase (FASN) [ 4 ] . (encyclopedia.pub)
Risperidone upregulates fatty acid synthase (FASN) and sterol regulatory element-binding protein 1 (SREBP1) expression in hepatocyte cultures and mouse liver by targeting the hepatic SREBP-1c/FASN couple, which is also one of the mechanisms by which risperidone induces weight gain ( 24 ). (frontiersin.org)
F 1 F 0 -ATP synthase is a large enzyme complex made up of over 22 subunits. (biomedcentral.com)
The preferred route for protons in the intermembrane space to re-enter the matrix, in an attempt to flow down the gradient and re-establish equilibrium, is to enter through the ATP synthase enzyme complex. (biomedcentral.com)
Experiments using purified enzymes from cows and yeast revealed that the number of protons required by ATP synthase to make a single ATP molecule is almost twice as high for lower eukaryotes as it is for animals[ 5 ]. (biomedcentral.com)
Thus, the production of ATP by the ATP synthase enzyme has significantly increased in efficiency during the evolution of multicellular organisms from early eukaryotic ancestors. (biomedcentral.com)
Disruption of adipocyte de novo lipogenesis (DNL) by deletion of fatty acid synthase (FASN) in mice induces browning in inguinal white adipose tissue (iWAT). (biomed.news)
However, a systematic analysis of fatty acid synthase across pan-cancers has not been carried out. (aging-us.com)
Methods: We investigated the oncogenic roles of fatty acid synthase in 33 cancers based on the cancer genome atlas and gene expression omnibus. (aging-us.com)
Results: Fatty acid synthase is profoundly expressed in most cancers and is an important factor in predicting the outcome of cancer patients. (aging-us.com)
Fatty acid synthase expression is related to tumor-infiltrating immune cells in tumors (e.g. (aging-us.com)
Moreover, hormone receptor binding- and fatty acid metabolic process-associated pathways are involved in the functional mechanisms of fatty acid synthase. (aging-us.com)
Conclusions: This study provides a complete understanding of the oncogenic role of fatty acid synthase in human tumors. (aging-us.com)
The Cancer Genome Atlas (TCGA) project and gene expression omnibus (GEO) dataset contain useful genomic information sets of various tumors [ 1 - 3 ] and can be employed to identify the potential oncogenic role of fatty acid synthase (FASN). (aging-us.com)
Starting from the N-terminus, these units include β-ketoacyl synthase (KS), acetyl/malonyl transacylase (AT/MT), β-hydroxyacyl dehydratase (DH), enoyl reductase (ER), β-ketoacyl reductase (KR), acyl carrier protein (ACP), and thioesterase (TE). (aging-us.com)

The resulting acetyl-CoA is carboxylated to yield malonyl-CoA by acetyl-CoA carboxylase (ACC). (encyclopedia.pub)
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. (smpdb.ca)
We explore which of these metabolite changes triggers adipose browning by generating eight adipose-selective KO mouse models with loss of ATP-citrate lyase (ACLY), acetyl-CoA carboxylase 1 (ACC1), ACC2, malonyl-CoA decarboxylase (MCD) or FASN, or dual KOs ACLY/FASN, ACC1/FASN, and ACC2/FASN. (biomed.news)

Transcripts encoding enzymes in photosynthesis and starch synthesis were instead down-regulated. (biomedcentral.com)
To be available for TAG synthesis, carbons from sucrose must first be converted to pyruvate through cytosolic or plastidic glycolytic pathways and at some point be imported into the plastid to yield acetyl-coenzyme A (CoA) which feeds fatty acid (FA) synthesis with carbon backbones. (biomedcentral.com)
The formation of fat synthesis mechanisms in fish cells and the enzymes involved there through aprocess based on coincidences is impossible. (questionsonislam.com)
By focusing on the critical roles of different metabolic programs, such as glycolysis, oxidative phosphorylation, fatty acid oxidation, fatty acid synthesis, and amino acid metabolism, as well as their essential regulators in modulating Treg proliferation, migration, and function, we hope to provide new insights into Treg cell-targeted antitumor immunotherapies. (biomedcentral.com)
Lipid synthesis requires bulk carbon skeleton acyl-CoAs, the transport of which depends on the acyl-CoA binding protein (ACBP). (biomedcentral.com)
Cells require a constant supply of energy to perform vital functions, including nutrient uptake, protein synthesis, DNA replication, and active transport across cell membranes. (microbiologynote.com)
enzyme domain p75NTR( POLK) is a family domain integration recognition that is most unrelated in synthesis polymerase origin( TLS) across nucleosome trans of Release points, last as purine insulin( Tg) and active( OGUA), back not as selected mast binds, enhanced as receptor stretch while person play( BPDE-G)( Zhang et al. (erik-mill.de)
A coenzyme A derivative which plays a key role in the fatty acid synthesis in the cytoplasmic and microsomal systems. (lookformedical.com)
Strikingly, adipose ACC1 KO induces a strong iWAT thermogenic response similar to FASN KO while also blocking malonyl-CoA and palmitate synthesis. (biomed.news)
Thus, ACC1 and FASN are strong suppressors of adipocyte thermogenesis through promoting lipid synthesis rather than modulating the DNL intermediates acetyl-CoA or malonyl-CoA. (biomed.news)

Here, transcriptome analysis and fatty acid profiling from developing V. galamensis seeds were integrated to uncover the critical metabolic pathways responsible for high EFA accumulation and identify the targets that could be used in assembly of EFA biosynthesis pathway in existing oilseed crops. (researchsquare.com)
Transcriptome sequencing revealed that all homologs induced the same general patterns with a drastic shift in gene expression profiles of leaves from that of a typical source tissue to a source-limited sink-like tissue: Transcripts encoding enzymes for plastid uptake and metabolism of phosphoenolpyruvate, fatty acid and oil biosynthesis were up-regulated, as were also transcripts encoding starch degradation. (biomedcentral.com)
We examined the enzyme protein and biosynthesis of human trifunctional protein harboring enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase activity in cultured skin fibroblasts from two patients with long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. (rhea-db.org)
A fatty acid coenzyme derivative which plays a key role in fatty acid oxidation and biosynthesis. (lookformedical.com)

d) It is highly significant in the liver and kid-neys of birds which excrete uric acid as the end product of purine metabolism and also of protein and amino acid catabolism. (biologydiscussion.com)
Drug metabolism is generally associated with liver enzymes. (nature.com)
It is an amino acid derivative and an essential cofactor for fatty acid metabolism. (lookformedical.com)
Perilipin 5 (PLIN5) is a lipid-droplet-associated protein that coordinates intracellular lipolysis in highly oxidative tissues and is thought to regulate lipid metabolism in response to phosphorylation by protein kinase A (PKA). (uci.edu)

However, adipocyte FASN knockout (KO) increases acetyl-coenzyme A (CoA) and malonyl-CoA in addition to depletion of palmitate. (biomed.news)
Preventing elevation of acetyl-CoA and malonyl-CoA by depletion of adipocyte ACLY or ACC1 in combination with FASN KO does not block the browning of iWAT. (biomed.news)
The human FASN protein is composed of six catalytic units. (aging-us.com)
Additionally, several features (e.g., gene expression, survival prognosis, genetic alteration, DNA methylation, protein phosphorylation, immune cells, or relevant cellular pathways) were gathered to evaluate the regulatory mechanism of FASN in the tumorigenesis of cancers. (aging-us.com)
Further, the "HomoloGene" function of the NCBI was used to conduct conserved functional domain analysis of the FASN protein in different species. (aging-us.com)

Initially, citrate is converted to acetyl-CoA by ATP-citrate lyase (ACLY). (encyclopedia.pub)

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (smpdb.ca)
We have identified a cytosolic acyl-CoA binding protein, with highly conserved amino acid residues and a typical acyl-CoA binding domain in N. caninum . (biomedcentral.com)

ELOVLs are located in the endoplasmic reticulum (ER) and catalyze FA elongation via the condensation of a malonyl-CoA to an acyl-CoA molecule to yield 3-ketoacyl-CoA, which is the first rate limiting step in the elongation cycle of FAs [ 8 ] . (encyclopedia.pub)
Search proteins in UniProtKB for this molecule. (rhea-db.org)

The re-entry of the protons occurs through the enzyme ATP synthetase. (histocutup.co.uk)

Functional annotation resulted in the identification of almost all genes involved in diverse lipid-metabolic pathways, including the novel fatty acid desaturase/epoxygenase, diacylglycerol acyltransferase 1 and 2, and phospholipid:diacylglycerol acyltransferases. (researchsquare.com)
Expression systems for lactic acid bacteria have been developed for metabolic engineering applications as well as for food-grade recombinant protein production. (biomedcentral.com)
It is generally assumed that unless they are genetically aberrant, normal cells are equipped with common metabolic machinery (i.e., transporters and enzymes) to cope with the changing nutritional environment. (wiley.com)
Cellular respiration is a vital metabolic process that occurs within cells, enabling the conversion of energy stored in carbohydrates into energy carriers, most notably adenosine triphosphate (ATP). (microbiologynote.com)
Through a series of interconnected metabolic pathways, the potential energy stored in the chemical bonds of these molecules is harnessed and transferred to energy carriers, which power other essential cellular processes. (microbiologynote.com)
The NADH and NADPH derived from various metabolic reactions in the mitochondrial matrix interact with the proteins of the mitochondrial respiratory chain and result in hydrogen ions (protons) being pumped out of the matrix into the space between the inner and outer mitochondrial membranes. (histocutup.co.uk)
Various metabolic pathways can feed into the citric acid cycle provided that they generate acetyl CoA. (histocutup.co.uk)
Lysosomal function is critical for organismal homeostasis-mutations in genes encoding lysosomal proteins cause severe human disorders known as lysosomal storage diseases, and lysosome dysfunction is implicated in age-associated diseases including cancer, neurodegeneration and metabolic syndrome. (stanford.edu)

To assess the quality of biodiesel produced, fatty acid methyl esters (FAME) composition was studied. (hindawi.com)
The NcACBP recombinant protein was able to specifically bind acyl-CoA esters in vitro . (biomedcentral.com)
Enzymes from the transferase class that catalyze the transfer of acyl groups from donor to acceptor, forming either esters or amides. (lookformedical.com)

Although lipids are a distinct class of biomolecules, we shall see that they often occur combined, either covalently or through weak bonds, with members of other classes of bio-molecules to yield hybrid molecules such as glycolipids , which contain both carbohydrate and lipid groups, "and lipoproteins , which contain both lipids and proteins. (medmuv.com)
A common saturated fatty acid found in fats and waxes including olive oil, palm oil, and body lipids. (lookformedical.com)
MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)

The diminution of trifunctional protein was associated with a decreased activity of enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and 3-ketoacyl-CoA thiolase, when measured using medium-chain to long-chain substrates. (rhea-db.org)
The 3-hydroxy-acyl-CoA dehydrogenase activity with medium-chain to long-chain substrates was decreased drastically, with minor changes in activities of the two other enzymes. (rhea-db.org)
Taken together, the results obtained show that in both patients, long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency is caused by an abnormality in the trifunctional protein, even though there is a heterogeneity in both patients. (rhea-db.org)
Complex II of the chain is the succinate dehydrogenase enzyme complex. (histocutup.co.uk)
As well as being an integral cofactor for succinate dehydrogenase, FAD also assists other enzymes that require oxidation-reduction support. (histocutup.co.uk)

To be somatic nucleus nucleotide through coupled uracil kDa at such cancers, transporters serve a scaffold, replaced to as activation deficit( TLS), which translocates form protein to Get complex classes. (erik-mill.de)

By comparison, we found that various genes associated with acyl editing, fatty acid β-oxidation, triacylglycerol assembly and oil-body formation had greater expression levels at middle developmental stage (38 DAP), which are consistent with the fast accumulation of EFA in V. galamensis developing seed, implying their fundamental roles in EFA production. (researchsquare.com)
However, we previously demonstrated that the grisemycin (grm) cluster contained cryptic dehydratase and epimerase genes by heterologous expression of this biosynthetic gene cluster in Streptomyces lividans and proposed that two genes (grmH and grmL) with unknown functions catalyze dehydration and epimerization reactions. (hokudai.ac.jp)
By the mid 1980s, techniques largely had switched from those of the biochemistry of intermediates and enzymes to the identification of mutations in genes. (medscape.com)

Intersecting analysis, molecular docking, and pathway validation analysis showed that risperidone influences the adipocytokine signaling pathway by targeting MAPK14 (mitogen-activated protein kinase 14), MAPK8 (mitogen-activated protein kinase 8), and RXRA (retinoic acid receptor RXR-alpha), thereby inhibiting long-chain fatty acid β-oxidation by decreasing STAT3 (signal transducer and activator of transcription 3) expression and phosphorylation. (frontiersin.org)

The following points highlight the five main enzymes involved in oxidative process. (biologydiscussion.com)
The electron carriers then enter the electron transport chain, located in the inner mitochondrial membrane, where oxidative phosphorylation takes place. (microbiologynote.com)

Enzyme Nomenclature, 1992) EC 4. (lookformedical.com)

a) Enzymes that catalyse the removal of hy-drogen from a substrate but use only oxy-gen as a hydrogen acceptor to form water as a reaction product (with the exception of uricase and monoamine oxidase which form H 2 O 2 ). (biologydiscussion.com)
Most frequently the process consists of the reaction of an acid with an alcohol in the presence of a trace of mineral acid as catalyst or the reaction of an acyl chloride with an alcohol. (lookformedical.com)
Although direct identification of abnormal protein structure still was not possible, such defects could be inferred, indirectly, by demonstrating alterations in the kinetic properties of patients' enzymes (ie, rates of reaction as concentrations of cofactor or substrate were varied) or in the rate at which heating the enzyme altered its catalytic properties. (medscape.com)

Enzymes that catalyze the cleavage of a carbon-carbon bond by means other than hydrolysis or oxidation. (lookformedical.com)
The resulting acetyl-CoA molecules enter the Krebs cycle, generating additional carbon dioxide, ATP, and electron carriers (such as NADH and FADH2). (microbiologynote.com)
The acetyl group of acetyl CoA contains two carbon atoms. (histocutup.co.uk)
A saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. (lookformedical.com)
The two-carbon acetyl group in acetyl-CoA is transferred to the four-carbon compound of oxaloacetate to form the six-carbon compound of citrate. (easyomics.org)

In this study, we confirmed that both GrmH and GrmL, which were shown to constitute a protein complex by a co-purification experiment, were required to catalyze the dehydration, epimerization, and proteolytic cleavage of a precursor peptide GrmA by in vivo experiments. (hokudai.ac.jp)

10% of that in control cells, due to a very rapid degradation of protein newly synthesized in the mitochondria. (rhea-db.org)
b) In cells from patient 2, the rate of degradation of newly synthesized trifunctional protein was faster than that in control cells, giving rise to a trifunctional protein amounting to 60% of the control levels. (rhea-db.org)
This enzyme is involved in the degradation of N -acetylneuraminate. (qmul.ac.uk)

An enzyme that catalyzes reversibly the conversion of palmitoyl-CoA to palmitoylcarnitine in the inner mitochondrial membrane. (lookformedical.com)
Subsequently, acyl-carnitines are translocated across the inner mitochondrial membrane by cartinine acyl translocase. (biomedcentral.com)

Then, 3-ketoacyl-CoA is reduced and dehydrated to produce trans-2-enoyl-CoA, which is finally reduced to form the elongated acyl-CoA. (encyclopedia.pub)

Mtb is equipped with enzymes that catalyse biotransformation reactions on xenobiotics with consequences either in its favour or as a hindrance by deactivating or activating chemical entities, respectively. (nature.com)

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity). (smpdb.ca)
CRISPR/Cas9 disruption of the mitochondrial citrate carrier showed that CIC is required for biochemical differentiation of trophoblasts. (biomed.news)

As electrons are shuttled through the complexes I, III and IV by electron carriers, protons (H + ) are moved from the mitochondrial matrix into the intermembrane space. (biomedcentral.com)

A change in structure was in those days thought to be due to a change in an amino acid somewhere in the peptide chain of the protein. (medscape.com)

This allows the recycling of the electron carriers (NADH) back into their oxidized forms (NAD+), enabling glycolysis to continue. (microbiologynote.com)

Catalytic heterogeneity of the mutant enzyme in two patients. (rhea-db.org)

Moreover, an intermediate-enzyme adduct with a NOS-covalent linkage was observed in the later site, where it acts as a two-scissile-bond linkage facilitating nucleophilic addition and cofactor-free decarboxylation. (hokudai.ac.jp)

Four protein complexes in the inner membrane make up the electron transport chain (ETC, also known as the electron transport system), which converts the redox energy stored as NADH and FADH 2 into chemical energy in the form of ATP. (biomedcentral.com)

Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2). (smpdb.ca)

g) This enzyme system contains copper, a component of several oxidase enzymes. (biologydiscussion.com)
The regulatory download Your Brain on Latino Comics: From Gus Arriola to Los Bros Hernandez (Cognitive Approaches to Literature and Culture) 2009 II hotspot partners mitotically act to the pain knowledge, where they are repaired by CD4+ particle pre-tRNAs for fatty oxidase( Berger & Roche 2009, Zhou & Blum 2004, Watts 2004, Landsverk et al. (evakoch.com)

Comparison of the stability and substrate specificity of purified peroxisomal 3-oxoacyl-CoA thiolases A and B from rat liver. (rhea-db.org)
globin in the presence is also activated into liver sites by AQP9 included in the enzyme heterodimer of reactions. (evakoch.com)

Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). (smpdb.ca)

The corresponding gene, AtWRINKLED1 ( AtWRI1, At3g54320), encodes a protein with two APETALA2-ethylene responsive element-binding protein (AP2/EREBP) motifs that is a signature for plant-specific transcription factors involved in a wide range of developmental processes [ 5 , 6 ]. (biomedcentral.com)
The energy released during cellular respiration, in the form of ATP and other energy carriers, fuels various anabolic processes within the cell . (microbiologynote.com)

Human biochemistry that involves enzymes usually performs optimally around a biologically neutral pH of 7.4. (hmdb.ca)

Here, we report a noncanonical FAD-dependent enzyme Orf1 that adds a glycine-derived N-formimidoyl group to glycinothricin to form the antibiotic BD-12. (hokudai.ac.jp)

In mammals, FA elongation depends on a set of enzymes termed elongation of very long-chain fatty acid enzymes (ELOVLs) [ 7 ] . (encyclopedia.pub)

In complexes, the other enzymes affect cleaved CBF1( or RBPJkappa), while in channels they are required Lag-1, immediately that the m ' CSL ' demonstrates separated been to this produced feature experience breast. (evakoch.com)

These include cytochromes, which are haem-containing proteins that use iron to carry electrons and coenzyme Q, which can transport both electrons and protons. (histocutup.co.uk)

The aggregation of both amyloid beta (Abeta) peptides extracellularly and Tau proteins intracellularly plays key roles in the pathological consequences of AD, which lead to cholinergic neurodegeneration and eventually death. (inra.fr)

In anabolism, water is removed from molecules (through energy requiring enzymatic chemical reactions) in order to grow larger molecules (e.g. starches, triglycerides and proteins for storage of fuels and information). (hmdb.ca)

The recombinant NcACBP protein was expressed to verify the binding activities of NcACBP in vitro , and the heterologous expression of NcACBP in Δacbp yeast in vivo . (biomedcentral.com)

It causes the production of abnormal proteins with impaired biological activity. (lookformedical.com)

This enzyme is also part of the citric acid cycle and uses the electron carrier flavin adenine dinucleotide (FAD/FADH). (histocutup.co.uk)

Anatomy5

Organisms10

Diseases1

Chemicals and Drugs88

Analytical, Diagnostic and Therapeutic Techniques and Equipment16

Phenomena and Processes26

Technology, Industry, Agriculture2

Information Science3

Health Care2

Acids43

Synthase15

Carboxylase3

Synthesis10

Biosynthesis4

Metabolism4

FASN5

Lyase1

Highly conserved2

Molecule2

Synthetase1

Metabolic8

Esters3

Lipids3

Dehydrogenase5

Transporters1

Genes3

Signaling pathway1

Oxidative2

Nomenclature1

Reaction3

Carbon5

Precursor1

Degradation3

Inner mitochon2

Enoyl1

Biotransformation1

Citrate2

Mitochondrial matrix1

Amino acid1

Glycolysis1

Catalytic1

Cofactor1

NADH1

Converts1

Oxidase2

Liver2

Methyl group1

Processes2

Biochemistry1

Form1

Elongation1

Complexes1

Protons1

Peptides1

Triglycerides1

Yeast1

Abnormal1

Electron1